Ditemukan 117 dokumen yang sesuai dengan query
This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how...
Weinheim, Germany: Wiley-Vch, 2008
e20375710
eBooks Universitas Indonesia Library
Classified by their mode of action, all important classes of analgesics are presented here, including recent developments that have not yet been introduced to the market. Altogether, more than 300 compounds are described. A carefully designed layout presents the most relevant information at a glance, including compound structure, physical properties,...
Weinheim, Germany: Wiley-Vch, 2002
e20375675
eBooks Universitas Indonesia Library
How are medicines transported intact through the body to their specific target sites without triggering side effects? The answer is "Drug targeting".
This thoroughly application-oriented book gives comprehensive answers to this and many other questions that confront scientists daily in chemical, pharmaceutical and medical research. A concise overview of the most...
Weinheim, Germany: Wiley-VCH, 2001
e20385352
eBooks Universitas Indonesia Library
Designed as a first-stop reference for researchers and professionals in toxicology, pharmacology and medicine, this handbook is the to tie together the knowledge from many disciplines that has so far been available only from widely dispersed sources in the primary literature. As such, it presents the complete picture on what...
Weinheim, Germany: Wiley-VCH, 2010
e20393909
eBooks Universitas Indonesia Library
Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease. The first part of the book surveys current methodologies for finding and validating drug candidates that act via...
Weinheim: Wiley-VCH, 2009
e20393916
eBooks Universitas Indonesia Library
With its particular emphasis on the constitutive activity of G-protein-coupled receptors (GPCRs)s, this book comprehensively discusses an important biological process that has not yet been covered in such depth in any other existing books on GPCRs. The international team of highly distinguished authors addresses in detail current models and concepts,...
Weinheim, Germany: Wiley-VCH, 2005
e20393932
eBooks Universitas Indonesia Library
Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically.
Despite their significance, until now, no book has been dedicated to hydrolysis...
Weinheim, Germany: Wiley-Vch, 2003
e20394191
eBooks Universitas Indonesia Library
Explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods....
Weinheim: Wiley-VCH, 2003
e20394257
eBooks Universitas Indonesia Library
The book covers a broad spectrum of topics, ranging from pioneering research in the field of classical steroid hormones to very recently discovered orphan receptors and their modulators. State of the art technologies are also discussed in the individual chapters that help to develop a deeper insight into the biochemical...
Weinheim, Germany: Wiley-VCH, 2008
e20394371
eBooks Universitas Indonesia Library
Contents:
1. Ethanol
2. Passivrauchen am Arbeitsplatz
3. Aenderung der Einstufung Krebserzeugender Arbeitsstoff...
Weinheim: Wiley-VCH, 1999
e20394419
eBooks Universitas Indonesia Library
