Ditemukan 117 dokumen yang sesuai dengan query
The challenge remains to find the proper combination of these techniques in view of their respective potential, limitations, and costs, in order to pick up the right compounds quickly while keeping the risk of eliminating ‘good’ candidates as low as possible. Potential and limitations of a number of approaches to...
Weinheim, Germany: Wiley-VCH, 2001
e20394491
eBooks Universitas Indonesia Library
The authors here a new approach, based on recent findings on an underestimated PAH components. They describe occurrence, occurrence and biological activity of a number relevant for humans polycyclic aromatic hydrocarbons and thus provide a comprehensive overview of the problem. The book is the result of intensive scientific work in...
Weinheim: Wiley-VCH, 2004
e20394501
eBooks Universitas Indonesia Library
This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for...
Weinheim, Germany: Wiley-VCH, 2010
e20394568
eBooks Universitas Indonesia Library
Rautio, Jarkko., editor
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing...
Weinheim: Wiley-VCH, 2011
e20394584
eBooks Universitas Indonesia Library
The book closes with chapters on recent progress in technologies: protein engineering to promote crystallization, micro-crystallization, and high-throughput crystallography. Withitsbroadperspective,thebookprovidesastate-of-the-artoverviewonimportant results and techniques that are relevant for protein 3D structure-based drug design...
Weinheim, Germany: Wiley-VCH, 2004
e20394586
eBooks Universitas Indonesia Library
Klebl, Bert., editor
This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current...
Weinheim: Wiley-VCH, 2011
e20394589
eBooks Universitas Indonesia Library
Computational methods are transforming the work of chemical and pharmaceutical laboratories. Increasingly faster and more exact simulation algorithms have made quantum chemistry a valuable tool in the search for active substances.
Written by a team of leading international quantum chemists, this book is aimed at both beginners as well as experienced...
Weinheim, Germany: Wiley-VCH, 2003
e20394593
eBooks Universitas Indonesia Library
Contents :
1. Zusammenfassung und Empfehlungen
2. AnlaB und Anliegen
3. Das Fachgebiet
4. Toxikologie in Deutschland
5. Toxikologie im Ausland
6. DFG-Denkschrift 1975 und ihre Folgen
7. Literatur
8. Anhan...
Weinheim, Germany: Wiley-VCH, 2000
e20395089
eBooks Universitas Indonesia Library
Im zweiten band dieses modular aufgebauten Lehrbuchs wird die exposition und toxische wirkung der wichtigsten toxischen chemikalien abgehandelt. (Nano-) partikuläre stoffe, metalle, anorganische und organische verbindungen werden systematisch betrachtet und in ihren chemischen eigenschaften, expositionen, wirkmechanismen und toxikodynamik beschrieben, ergänzt durch experimentelle daten von mensch und tier. ein besonderes highlight...
Weinheim: Wiley-VCH, 2010
e20395091
eBooks Universitas Indonesia Library
Perfekt abgestimmt auf die moderne Ausbildung zum Toxikologen, werden in diesem Lehr- und Prüfungsbuch alle wichtigen Konzepte und wissenschaftlichen Grundlagen der Toxikologie erklärt: von der molekularen Toxikologie bis hin zu Risk Assessment und Epidemiologie. Besonderes Highlight sind mehrere Kapitel zu den aktuellen Hauptarbeitsfeldern der Toxikologie, u.a. die Kontrolle und Bewertung...
Weinheim: Wiley-VCH, 2010
e20395092
eBooks Universitas Indonesia Library
