Ditemukan 40 dokumen yang sesuai dengan query
Kazmierski, Wieslaw M., editor
This book focuses on new small molecule approaches to combat viral infections. The chapters describe the discovery and development from bench through the clinic of relatively recently-approved antiviral drugs and compounds in advanced clinical development. Organized by a virus (such as HIV, HCV, RSV, influenza, HBV and CMV) and written...
New Jersey: John Wiley & Sons, 2011
e20375714
eBooks Universitas Indonesia Library
Glennon, Richard A., editor
Although somewhat labor intensive, Drug Discrimination (DD) is of enormous applicability to the understanding of drug action. Drug discrimination : applications to medicinal chemistry and drug studies covers the practical applications of drug discrimination studies for medicinal chemistry, including strengths and limitations versus other pharmacological methods for evaluating drug action....
Hoboken: John Wiley & Sons, 2011
e20385337
eBooks Universitas Indonesia Library
Klebl, Bert., editor
This timely guide to kinase inhibitor drug development is the first to cover the entire drug pipeline, from target identification to compound development and clinical application. Edited by the pioneers in the field, on the drug development side this ready reference discusses classical medicinal chemistry approaches as well as current...
Weinheim: Wiley-VCH, 2011
e20394589
eBooks Universitas Indonesia Library
This book about protein-protein Interactions as drug targets, targeting the MDM2-p53 protein-protein interaction for new cancer therapeutics, the development of small-molecule IAP antagonists for the treatment of cancer, protein-protein interaction targets to inhibit HIV-1 infection, inhibitors of protein-protein interactions paramyxovirus fusion ? a focus on respiratory syncytial virus, rational design...
Berlin: Springer, 2012
e20406020
eBooks Universitas Indonesia Library
Dickenson, Jhon P., author
Chichester, West Sussex: Wiley-Blackwell, 2013
615.19 MOL
Buku Teks Universitas Indonesia Library
Anthony R.M. Coates, editor
This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed that there is a large...
Berlin: [, Springer], 2012
e20417720
eBooks Universitas Indonesia Library
Indah Pratiwi, author
ABSTRAK
Kanker merupakan suatu penyakit yang dapat terjadi karena adanya kegagalan apoptosis. Kegagalan apoptosis ini disebabkan karena MDM2 menghambat aktivitas dari p53 sehingga procaspase-3 tidak teraktivasi menjadi caspase-3. Saat ini, pengobatan kanker telah banyak diterapkan. Namun pengobatan yang lebih efektif selalu dibutuhkan karena penyakit kanker terus bermutasi. Pencarian pun dilakukan dari...
2017
S68473
UI - Skripsi (Membership) Universitas Indonesia Library
This book provides an introduction to the field of biomarkers, how they have been and can be used, and how different approaches can be used to identify, characterize, and monitor biomarkers. The book has chapters on topics including HIV, Cancer, Parkinson's, vascular injury, environmental exposure. A following section discusses the...
Hoboken, New Jersey: John Wiley & Sons, 2010
e20375770
eBooks Universitas Indonesia Library
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. The authors discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining...
Weinheim: Wiley-VCH, 2006
e20395921
eBooks Universitas Indonesia Library
This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition. Additionally, the book covers the inhibition of drug metabolizing and disposition enzymes including transporters (mostly "bad" or "undesirable" enzyme inhibition) as well as the...
Hoboken: John Wiley & Sons, 2010
e20393914
eBooks Universitas Indonesia Library
