Ditemukan 40 dokumen yang sesuai dengan query
With chapters provided by international leading experts, this book covers the recent advances in protein and peptide mass spectrometry. Focusing on the pharmaceutical industry, it addresses both emerging techniques, including imaging mass spectrometry, ion mobility, and microwave-assisted mass spectrometry, and recent applications, including pharmaceutical analysis throughout the drug development cycle....
Hoboken: John Wiley & Sons, 2012
e20394585
eBooks Universitas Indonesia Library
This book is the first systems biology text to focus on how systems biology can be specifically applied to enhance drug discovery and development, with particular emphasis on real-world examples. Other texts on systems biology to date have focused on particular subdisciplines of systems biology (such as cellular networks) and...
Hoboken: John Wiley & Sons, 2012
e20394638
eBooks Universitas Indonesia Library
Chemogenomics brings together the most powerful concepts in modern chemistry and biology, linking combinatorial chemistry with genomics and proteomics.
This first reference devoted to the topic covers all stages of the early drug discovery process, from target selection to compound library and lead design.
With the combined expertise of 20...
Weinheim: Wiley-VCH Verlag, 2004
e20376579
eBooks Universitas Indonesia Library
Lin, Guo-Qiang, editor
Presenting an overview of chiral drugs and their impact on the pharmaceutical industry, Chiral drugs : chemistry and biological action provides an integrated perspective of chiral drugs from concept, synthesis, and pharmaceutical properties. The book includes important chiral technologies and reviews of 200 chiral drugs that have either been approved...
Hoboken: John Wiley & Sons, 2011
e20376590
eBooks Universitas Indonesia Library
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early drug development : strategies and routes to first-in-human trials guides drug development organizations in preparing and submitting an Investigational New Drug (IND) application. By explaining the nuts and bolts of...
Hoboken: John Wiley & Sons, 2010
e20393907
eBooks Universitas Indonesia Library
Sotriffer, Christoph., editor
Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional structures of both the small and large molecule are known, their interaction can be tested by computer simulation with a reasonable...
Weinheim: Wiley-VCH, 2011
e20395196
eBooks Universitas Indonesia Library
Explaining the assessment of potential drug compounds, this is an ideal introductory reference for those new to drug discovery. It includes sections on pharmacokinetics and drug metabolism, integration of pharmaceutical development, and predictive safety assessment. Topics include: cost analysis, drug transporters, cytochrome P-450 and drug-drug interactions, plasma protein binding, assessing...
Hoboken: John Wiley & Sons, 2010
e20393919
eBooks Universitas Indonesia Library
Tabrizi, Mohammad A., editor
Translational strategies for development of antibody-based therapeutics should allow understanding of the relationship between the ?unit dose? and ?unit effect? with respect to both beneficial and deleterious effects from early stages of development. The flow of information from later to earlier stages of development should provide opportunities to facilitate selection...
New York: [Springer Science , ], 2012
e20420843
eBooks Universitas Indonesia Library
This book provides an overview of different protein kinases, structure, function, regulation, and their role in cancer. It combines kinase biology with chemistry and pharmacology applications for discovery and development of cancer drugs. The text also describes existing and emerging kinase inhibitors, focusing mostly on small molecules but also alternative...
Hoboken, New Jersey: John Wiley & Sons, 2010
e20394639
eBooks Universitas Indonesia Library
The Drug Discovery Handbook gives professionals a tool to facilitate drug discovery by bringing together, for the first time in one resource, a compendium of methods and techniques that need to be considered when developing new drugs. This comprehensive, practical guide presents an explanation of the latest techniques and methods...
Hoboken, N.J. : Wiley-Interscience , 2005
R 615.19 DRU
Buku Referensi Universitas Indonesia Library
