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"An ulcer is an area of discontinuity of an epithelial surface. Ulceration is the commonest oral soft tissue disorders and vary greatly in term of etiology signs and symptoms, prognosis and treatment. Abnormalities of immune system can cause oral mucosal ulceration. The purpose of this paper is to discuss the management of some of the more common oral ulcer associated with immunologic disorders. Because the natural history and treatment varies with the diagnosis, the practitioner should became familiar with the clinical aspects of the various type of ulcerations so that appropriate treatment can be instituted."

"The oral mucosa is the target of a number of infectious processes caused by a range of organism. Viruses is one of the organism which is considered in oral mucosa damage. Recently, the main viruses causing oral mucosal infections are the large herpes group. This article discuss herpes simplex virus and varicella zoster virus that cause herpetic stomatitis and gherpes zoster with particular attention to the typical oral manifestations current treatment options. Dentists should recognice the clinical appearances of the diseases, so the appropriate therapy can be done."