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"Joint sealant is used for concrete pavement joints. To fulfill jpint sealant requirements, laboratory tests have been carried out except weathering test, therefore for this purpose, experiments by simulation on concrete pavement is required in order to conform to all requirements for use in sealing joints in concrete pavements..."

"Latar belakang: Perdarahan sendi berulang merupakan morbiditas utama pada pasien hemofilia karena dapat menimbulkan artropati hemofilik yang menyebabkan keterbatasan gerak dan disabilitas sehingga menurunkan kualitas hidup. Penelitian bertujuan mengetahui korelasi pemeriksaan klinis sendi, penilaian aktivitas fungsional dan kualitas hidup pada anak hemofilia.Metode: Penelitian dengan desain potong lintang di RSCM pada Agustus−November 2022 pada anak 4−16 tahun, hemofilia A atau B derajat sedang atau berat yang mengalami perdarahan sendi berulang. Penelitian dilakukan dengan menilai HJHS, PedHALshort serta Haemo-QoL dan mencari korelasi skor HJHS dengan skor PedHALshort dan Haemo-QoL.Hasil: Sebanyak 95 subyek hemofilia, dengan hemofilia A (77,3%) dan 70,1% hemofilia berat. Skor HJHS median 4 (1−9), skor PedHALshort median 74,5 (62,73-89,09), skor Haemo-QoL mean (SD) 74,51 (15,58). Skor HJHS berkorelasi negatif sedang dengan PedHALshort (r= -0,462, p< 0,0001), skor HJHS berkorelasi sedang dengan Haemo-QoL (r= 0,469, p< 0,001).Simpulan: Semakin tinggi skor HJHS menunjukkan adanya kerusakan pada sendi maka semakin rendah skor PedHALshort dan semakin tinggi skor Haemo-QoL yang menunjukkan semakin terganggu aktivitas fungsional serta kualitas hidupnya.

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Background: Recurrent joint bleeding is the major morbidity in patient with hemophilia that can cause hemophilic arthropathy causes limitation of daily activities, disability, and reducing quality of life. Research objective are to determine the relationship between the clinical evaluation of joints, the assessment of functional activity determined and assessment of the quality of life with HJHS, so we can diagnose arthropathy, prevent disability and better management.

Methods: Study with cross-sectional design at RSCM on August-November 2022, children aged 4-16, with moderate or severe hemophilia A and B with recurrent joint bleeding. The study was conducted by assessing HJHS, PedHALshort and Haemo-QoL, determine the relationship between HJHS with PedHALshort and Haemo-QoL score.

Result: A total of 95 hemophilia subjects, with hemophilia A (77.3%) and 70.1% severe hemophilia. HJHS median score 4 (1-9), PedHALshort median score 74.5 (62.73-89.09), Haemo-QoL mean (SD) 74.51 (15.58). The HJHS score had a moderate negative correlation with PedHALshort (r= -0.462, p<0.0001), the HJHS score had a moderate correlation with Haemo-QoL (r= 0.469, p<0.001).

Conclusion: The higher of HJHS score indicates a joint disorder, the lower of PedHALshort and the higher of Haemo-QoL indicates the more impaired functional activity and poorer quality of life."

"Latar Belakang: Artritis Reumatoid (AR) merupakan penyakit inflamasi sendi autoimun yang multi-sistemik persisten, eksaserbatif dan progresif. Anti-mutated citrullinated vimentin antibodies (Anti MCV) adalah autoantibodi golongan anti citrullinated protein antibody (ACPA) yang memiliki sensitifitas sama namun lebih spesifik dibandingkan dengan anti cyclic citrullinated protein (Anti CCP). Anti MCV berkaitan erat dengan gen HLA DRB1*04 yang berperan penting dalam patogenesis AR. Studi korelasi anti MCV dengan destruksi sendi dan aktifitas penyakit masih kontroversial dan karakteristik pasien AR di Indonesia yang berbeda, menjadi alasan penting dilakukannya penelitian ini. Tujuan: Mengetahui hubungan antara kadar anti MCV dengan destruksi sendi dan aktifitas penyakit pada pasien artritis reumatoid. Metode: Penelitian ini merupakan studi potong lintang pada 37 pasien AR berdasarkan kriteria EULAR/ACR 2010 yang berobat di poliklinik Reumatologi RSCM periode September-Nopember 2014 dengan metode consecutive sampling. Anti MCV diukur dengan metode ELISA. Penilaian destruksi sendi menggunakan skor Sharp yang dimodifikasi Van der Heijde (SSvH) sedangkan aktifitas penyakit dinilai dengan disease activity score (DAS) 28 meliputi DAS 28-CRP dan DAS 28-LED. Korelasi anti MCV dengan destruksi sendi dan aktifitas penyakit dinilai dengan uji korelasi Spearman serta p untuk kemaknaan. Data penyerta lain adalah data demografis, jenis dan dosis terapi, status gizi, faktor reumatoid (FR), CRP, LED, dan darah tepi. Hasil: Sebanyak 37 subjek diikutsertakan pada penelitian ini, dengan 34 (91,9%) adalah perempuan. Anti MCV positif ditemukan 26 subjek (70,3%), sedangkan FR positif ditemukan 21 (56.%). Median anti MCV didapatkan 26 IU/ml (minimal 10 IU/ml, maksimal 151 IU/ml) termasuk titer rendah. Median SSvH yaitu 31 (2-107), dengan nilai median erosi 5(0-49) dan joint space narrowing (JSN) 26 (0-64). Rerata nilai DAS 28-CRP 2,69 (SB 1,34) dan median DAS 28-LED 4,08 (2,10-5,97) yang masing-masing termasuk dalam kelompok aktivitas penyakit rendah dan sedang.Pada analisis bivariat didapatkan korelasi positif yang lemah antara anti MCV dengan SSvH sebesar r = 0,393 (p=0,016) dan korelasi positif yang lemah antara anti MCV dengan skor DAS 28-CRP (r=0,365, p=0,013) namun tidak ada korelasi antara anti MCV dengan skor DAS 28-LED. Simpulan: Terdapat korelasi positif lemah yang bermakna antara titer anti MCV dengan destruksi sendi dan skor aktivitas penyakit DAS 28-CRP, korelasi antara titer anti MCV dengan skor DAS 28-LED tidak ada.

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Background: Rheumatoid Arthritis is a multi-systemic, persistent, exasperated and progressive auto immune joint inflamation disease. Anti-mutated citrullinated vimentin antibodies (Anti MCV) is an auto antibody in the category of anti citrullinated protein antibody (ACPA) that has same sensitivity but more specific compared with anti cyclic citrullinated protein (anti CCP). Anti MCV is closely related to gen HLA DRB1*04 which has important role in pathogenesis of rheumatoid arthritis. Study on correlation between anti MCV and joint destruction and disease activity is still controversial and the different characteristics of AR patients in Indonesia become a strong reason for this study.

Objective: The aim of this study was to described the correlation between anti-mutated citrullinated vimentin (anti MCV) with joint destruction and disease activity of in rheumatoid arthritis patients.

Methods: This is a cross-sectional study on 37 RA patients based on criteria of EULAR/ACR 2010 who came to Rheumatology outpatient clinic Cipto Mangunkusumo Hospital, period of September ? November 2014 with the method of consecutive sampling. Anti MCV is measured with ELISA method, while joint destruction is scored with Sharp score modified with Van der Heijde ( SSvH ). disease activity score (DAS) 28 is used in disease activity covering DAS 28-CRP and DAS 28-LED. Correlation between anti MCV and joint destruction as well as disease activity is measured with Spearman correlation test with p for significance. Other supporting data include demography, type and dose of therapy, nutrition status, rheumathoid factor, CRP, LED, and peripheral blood.

Results: 37 subjects were taken into this study, with 34 (91,9%) are women. Positive anti MCV was found in 26 subjects (70,3%) while positive FR was found in 21 subjects (56%). Median of anti MCV was obtained 26 IU/ml (minimal 10 IU/ml, maximal 151 IU/ml )which is including in low titer. Median of SSvH was 31 (2 ?107) with erosion median score of 5 (0-49) and joint space narrowing (JSN) of 26 (0-64). Average score of DAS 28-CRP was 2,69 (SD1,34) and median score of DAS 28-LED was 4,08 (2,10-5,97), each of which is included in low and medium disease activity. In bivariate analysis it?s found that there is a weak significant positive correlation between anti MCV and SSvH of r = 0,393 (p=0,016) and between anti MCV and score of DAS 28-CRP (r= 0,365 , p=0,013) but there is no correlation between anti MCV and score of DAS 28-LED.

Conclusion: There is a weak significant positive correlation between anti MCV and joint destruction and level of disease activity score DAS 28-CRP. Apart from that, there is no correlation between anti MCV and DAS 28-LED."

"Nyeri sendi merupakan salah satu gangguan pada sistem muskuloskeletal yang mengalami perubahan akibat proses penuaan. 66 % lansia yang tinggal di komunitas mengalami nyeri sendi. Nyeri kronis memiliki implikasi besar bagi kesehatan, fungsi, dan kualitas hidup lansia. Penelitian ini bertujuan mengetahui pengaruh latihan yoga ringan terhadap nyeri sendi dan status kesehatan lansia di Kota Depok. Desain penelitian ini menggunakan quasi experimental dengan pendekatan pre and post with control group. Intervensi yang diberikan berupa latihan yoga ringan. Pengambilan sampel dengan cara multistage random sampling dengan jumlah sampel 74 lansia. Instrumen penelitian yang digunakan adalah indeks WOMAC nyeri dan survey kesehatan Short Form-12 (SF-12). Analisis bivariat menunjukkan latihan yoga ringan berpengaruh terhadap tingkat nyeri (p=0,000) dan status kesehatan (p=0,0000). Latihan yoga ringan layak dijadikan sebagai salah satu intervensi keperawatan untuk menurunkan nyeri sendi dan meningkatkan status kesehatan lansia.

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Joint pain is one of the problems in musculoskeletal system associated with aging process. Approximately 66% older person in the community experiencing joint pain. Chronic pain has a big impact on older person health, function, and quality of live. The aim of this study was to identify the effect of gentle yoga exercise on joint pain and health status of elderlies at Depok's City. The design of this study was quasi experimental with pre and post with control group. Gentle yoga exercise was used as the intervention of this study. A total number of 74 older person was taken using multistage random sampling. The instruments used were WOMAC pain and health survey Short Form-12 (SF-12). Bivariate analysis showed pointing out gentle yoga exercises affected the level of pain (p = 0.000) and health status (p = 0.0000). Gentle yoga exercises could be one of the nursing intervention to decrease joint pain and improve health status in older person."

"Penelitian ini bertujuan mengetahui efektivitas pre ambulasi dan latihan ROM terhadap peningkatan luas gerak sendi pasca bedah fraktur ekstremitas bawah. Desainnya adalah quasi eksperimen dengan pretest-posttest with control terhadap 15 responden kelompok intervensi dan 15 kelompok kontrol. Kelompok intervensi diberikan pre ambulasi dan latihan ROM selama 5 hari, 3 kali sehari, selama 15 menit, sedangkan kelompok kontrol diberikan latihan ROM, menggunakan goniometer sebelum dan setelah intervensi. Hasil penelitian menunjukkan tidak ada perbedaan bermakna peningkatan luas gerak sendi antara kedua kelompok, dimana pangkal paha p= 0.092, lutut p= 0.001, dan kaki p= 0.495. Latihan ini menjadi standar prosedur pasien pasca bedah fraktur ekstremitas bawah.

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This study aims to know the effectiveness of pre ambulation and ROM exercises to increase joint range of motion post-surgical in fractures of the lower limb. The design was quasi experimental pretest-post test with control of the 15 respondents intervention group and 15 the control group. The intervention group received pre ambulation and ROM exercises for 5 days, three times a day, 15 minutes. The control group was given ROM training course, with a goniometry before and after the intervention. The results shows no significant difference obtained average - the average increase joint range of motion between two groups in which to groin p= 0.092, knee p= 0.001, and feet p= 0.495. This exercises may be standard procedure in patients with postoperative lower extremity fractures."

"Peristiwa gempa bumi yang cukup sering terjadi di Indonesia seketika dapat merusak bahkan meruntuhkan seluruh komponen bangunan. Maka selayaknya bangunan yang dibangun di Indonesia memiliki sistem struktur penahan gempa dimana salah satu sistem struktur penahan gempa yang paling sering digunakan ialah Special Moment Resisting Frame dikarenakan daktilitasnya yang lebih tinggi. Mekanisme keruntuhan SMRF diawali dengan proses pelelehan yang ditandai dengan munculnya sendi plastis. Pengaruh target sendi plastis pada kolom dasar dengan mekanisme leleh lentur terhadap perilaku struktur secara keseluruhan terlihat dari analisis pushover dimana daktilitas struktur akan menurun. Selain itu, digunakan dua profil yang berbeda untuk membandingkan penggunaan profil CFST dan baja WF dimana profil WF memiliki kekuatan, kekakuan, dan daktilitas yang lebih tinggi. Penggunaan sambungan semi-rigid untuk suatu struktur memiliki pengaruh dimana kekuatan dan kekakuannya menurun sedangkan daktilitasnya akan meningkat. Penelitian ini menggunakan dua program yaitu ETABS untuk perancangan bangunan serta DRAIN-2DX untuk analisis kinerja struktur.

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The earthquake phenomenon that usually occur in Indonesia can ruin or even destroy building components immediately. Therefore, buildings that constructed in Indonesia should have an earthquake resistance system, one of them is Special Moment Resisting Frame. This system has widely used in many buildings because it has high ductility and ability to dissipating energy. Collapse mechanism of SMRF building starts with yielding that marked by the existence of plastic hinge. The effect of plastic hinge that occur in column bases with flexural yielding mechanism on behavior of the overall structure can be seen from pushover analysis results which the ductility of structure will be reduced. Furthermore, the use of different profile Wide Flange and Concrete Filled Steel Tubes in the same building can affect the performance of that building, which the building with WF profile has higher strength, stiffness, and ductility. The type of connection that used is also affect performance of the buildings. Strength and stiffness will reduce while the ductility will increase. This research use two programs which is ETABS for designing the building and DRAIN 2DX for performance building analysis."