Hasil Pencarian  ::  Simpan CSV :: Kembali

""This new book carries on a strong tradition of diagnostically oriented texts established by the Biopsy Interpretation Series, in the present case focused on lesions of the Central Nervous System. Our purpose is to provide a practical guide and concise reference that can be a companion text for the general surgical pathologist, trainees in pathology and neuropathology, and clinicians who treat patients with neurological diseases that require surgical sampling. Given the heavy orientation of the Biopsy Interpretation Series to the busy and serious-minded diagnostician, we have taken this opportunity to create something new and, we think, useful. While there are certainly several excellent books on neuropathology and surgical neuropathology, the majority are reference texts that are comprehensive and encyclopedic, making them less than optimal on a daily basis to assist with interpretation. Because the central concern here is with establishing the correct diagnosis, the content is aimed at anticipating difficult diagnostic decisions and providing concise and reliable guide to their resolution"--Provided by publisher."

"Various aspects, including diagnosis, therapy, and prognosis, of two brain tumors (meningioma and schwannoma) , of brain tumors are discussed in this volume. Insights on the understanding of molecular pathways involved in brain tumor biology are explained. For example, the role of E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling is discussed in detail. Such information will lead to the development of effective aniicancer drugs. The role of molecular genetics and epigenetic mechanisms in schwannomas is explained. Also, is explained the role of cyclin D1 in vestibular schwannoma. The determination of subtypes of meningiomas using perfusion magnetic resonance imaging is explained. Diagnosis of incidentally discovered meningioma and cystic papillary meningioma is also included. Diagnosis of facial nerve schwannoma, vestibular schwannoma, and intermediate nerve schwannoma is explained. Treatments for atypical meningioma, oncocytic meneingioma, intracranial meningioma, and cavernous are presented. Therapeutic methods such as neurosurgery, Gamma knife radiosurgery, and adjuvant radiation for this cancer are included. Large number of other treatments, including radiosurgery, retrosigmoidal craniotomy, and immunotherapy, for vestibular schwannoma patients are detailed."

"Pandemi COVID-19 membawa dampak besar pada pembelajaran anatomi. Pembelajaran anatomi yang secara konvensional dilakukan berbasis kadaver tidak dapat dilakukan atau hanya dapat dilakukan secara terbatas. Aplikasi anatomi tiga dimensi hadir sebagai media pembelajaran anatomi yang dapat memudahkan mahasiswa memahami struktur dan topografi secara akurat. Penelitian ini dilakukan untuk mengetahui hubungan antara penggunaan aplikasi anatomi 3D dengan peningkatan hasil pembelajaran anatomi (nilai pre-post test) sistem saraf pusat pada mahasiswa FKUI angkatan 2023. Desain penelitian yang digunakan adalah quasi-eksperimental. Tiga puluh satu subjek dibagi menjadi dua kelompok yaitu menggunakan aplikasi anatomi 3D (n = 14) dan tidak menggunakan aplikasi anatomi 3D (n =17). Kedua kelompok diberikan materi tambahan berupa referensi buku anatomi. Dilakukan pre-test dan post test pada kedua kelompok untuk menilai hasil pembelajaran. Analisis data dilakukan uji Spearman rank correlation menggunakan aplikasi SPSS ver. 24. Ditemukan korelasi nilai r = 0,07 dengan nilai p = 0,7 (p > 0,05) antara hasil pembelajaran dan penggunaan aplikasi anatomi 3D. Terdapat peningkatan hasil belajar yang lebih tinggi pada kelompok yang menggunakan aplikasi anatomi 3D (30,00) dibandingkan dengan yang tidak menggunakan aplikasi anatomi 3D (26,47). Terdapat hubungan yang sangat lemah dengan tendensi tidak signifikan antara penggunaan aplikasi anatomi 3D dengan peningkatan hasil pembelajaran anatomi (nilai pre-post test) sistem saraf pusat pada mahasiswa FKUI angkatan 2023. Kedua kelompok mengalami peningkatan hasil pembelajaran. Diperlukan analisis lebih lanjut pengaruh preferensi metode pembelajaran anatomi, kemampuan spasial, gaya belajar, dan kecepatan belajar mahasiswa terhadap hubungan antara penggunaan aplikasi anatomi 3D dan hasil pembelajaran anatomi.

---

The COVID-19 pandemic has had a significant impact on anatomy education. Conventional anatomy learning based on cadavers cannot be conducted or can only be done in a limited manner. Three-dimensional anatomy applications are presented as a learning tool that can facilitate students in understanding anatomical structures and topography accurately. This research was conducted to determine the relationship between the use of 3D anatomy applications and the improvement in central nervous system anatomy learning outcomes (pre-post test scores) among 2023 students of the Faculty of Medicine, Universitas Indonesia. The research design used is quasi-experimental. Thirty-one subjects were divided into two groups: one using 3D anatomy applications (n = 14) and one not using 3D anatomy applications (n = 17). Both groups were provided with additional anatomical reference materials. Pre- tests and post-tests were conducted on both groups to assess learning outcomes. Data analysis was performed using the Spearman rank correlation test with SPSS version 24. A correlation with a value of r = 0.07 and a p-value of 0.7 (p > 0.05) was found between learning outcomes and the use of 3D anatomy applications. There was a higher improvement in learning outcomes in the group that used 3D anatomy applications (30.00) compared to the group that did not use 3D anatomy applications (26.47). There is a very weak and non-significant correlation between the use of 3D anatomy applications and the improvement in central nervous system anatomy learning outcomes (pre-post test scores) among 2023 students of the Faculty of Medicine, Universitas Indonesia. Both groups experienced an improvement in learning outcomes. Further analysis is needed to understand the influence of students' preference for anatomy learning methods, student’s spatial abilities, learning styles, and learning speed on the relationship between the use of 3D anatomy applications and anatomy learning outcomes."

"The most recent developments in diagnostic and therapeutic aspects of gliomas (glioblastoma) in the brain are presented. The importance of personalized medicine and clinical validation for targeted therapy are discussed. The identification of various types of biomarkers (determined by molecular genetics) is included, along with their advantages and limitations as markers in tumor detection and diagnosis. The identification and validation of brain cancer (glioblastoma) genes are discussed. The role of cancer stem cells in the initiation and persistence of malignant gliomas is explained, response of glioblastoma cancer stem cells to various growth factors, such as epidermal growth factor receptor kinase inhibitor, is explained. The use of surgical resection, chemotherapy (e.g., temozolomide), immunotherapy, and radiation therapy for glioblastoma patients is included. Biological impediments for chemotherapy and radiotherapy for malignant glioblastoma are pointed out. Standard (established) as well as newer imaging modalities (proton magnetic resonance spectroscopy) are discussed. Also included are proton magnetic resonance spectroscopy in intracranial gliomas, and the use of proton magnetic spectroscopic imaging in determining the infiltration zone in gliomas. The role of molecular signaling in the CNS cancer development is explained, including cell death signaling in glioblastoma multiforme."