Hasil Pencarian  ::  Simpan CSV :: Kembali

"The Handbook of the Psychology of Aging has become the definitive reference source for information on the psychology of adult development and aging. It provides comprehensive reviews of research on biological and social influences on behavior and age-related changes in psychological function. The seventh edition of the Handbook will contain all new material and include an entirely new section devoted to what neuroscience has discovered on cognitive aging. Contains all the main areas of psychological gerontological research in one volume Entire section on neuroscience and aging Begins with a section on theory and methods Edited by one of the father of gerontology (Schaie) and contributors represent top scholars in gerontology"

"Pendahuluan: Penuaan ditandai dengan banyak hal salah satunya penurunan fungsi kognisi akibat neurodegenerasi, proses yang berkaitan dengan penurunan kadar Brain-derived Neurotrophic Factor (BDNF) sebagai faktor pertumbuhan dalam regenerasi dan pemeliharaan sistem syaraf. Jumlah lansia yang akan meningkat di masa depan menuntut dunia kesehatan untuk mencari pencegahan proses neurodegenerasi ini. Objektif: Meneliti efek Centella asiatica (CA) terhadap fungsi kognisi dan kadar BDNF pada jaringan otak tikus Sprague-Dawley tua. Metode: Penelitian ini menggunakan Tikus Sprague-Dawley (SD) jantan berusia 20-24 bulan sebagai tikus tua dan 8-12 minggu sebagai kelompok tikus muda sebagai pembanding. Tikus-tikus tersebut dibagi menjadi 4 kelompok: kelompok kontrol negatif (diberikan akuades), kelompok kontrol positif (diberikan suplementasi Vitamin E 6 IU/pemberian), kelompok tikus muda berusia 8-12 minggu sebagai perbandingan (diberikan akuades), dan kelompok perlakuan yang diberikan ekstrak etanol daun CA yang diadministrasikan secara oral (300 mg/kg BB/hari) selama 28 hari, 2 kali perlakuan per hari. Selama penelitian, dilakukan pengujian memori jangka pendek menggunakan Y-maze. Pada akhir penelitian dilakukan terminasi dan pengukuran kadar BDNF otak tikus. Hasil: Hasil analisis statistik menunjukkan konsentrasi rata-rata BDNF 44.09±3.854 pada kontrol negatif, 43.09±11.99 pada kontrol positif, 30.2±12.33 pada tikus muda, dan 65.88±13.46 pada kelompok perlakuan CA (mg/pg protein). Kelompok CA memiliki perbedaan yang signifikan dibanding kontrol negatif (p=0,0189). Sedangkan pada uji memori jangka pendek menggunakan Y-maze, tidak ditemukan perbedaan signifikan. Kesimpulan: Hasil menunjukkan pemberian CA efektif dalam meningkatkan kadar BDNF otak tikus SD, sehingga diketahui memiliki efek neuroprotektif. Namun CA tidak ditemukan memiliki efek yang signifikan pada fungsi kognisi tikus SD yang mengalami penuaan.

---

Background: Functional decrease in learning and memory is one of the characteristics of the aging process. Studies showed that lower concentration of Brain-derived Neurotrophic Factor (BDNF) found on the brain, play a role in the phenomenon. BDNF is a growth factor that have a rol eon neuron regeneration and maintenance.

Objective: To determine whether a herbal, Centella asiatica (CA) would increase the BDNF level on the aging brain tissue neurodegeneration.

Methods: Male Sprague-Dawley rats aged 20-24 months as the aged rats and 8-12 weeks as the young rats that used in the study were divided into: negative control (given aquadest), positive control (supplementation of Vitamin E of 6 IU), young rats as a comparison (8-12 weeks old), and treatment groups, which were given ethanol extract of CA leaf administered orally (300 mg/kg BW) for 28 days with each days the treatment were given twice. The short term memory were analyzed by using Y-maze. The rats were terminated and the brain BDNF levels were assessed at the end of the study.

Results: The results showed mean ± SD concentration for BDNF were 44.09±3.854 (negative control), 43.09±11.99 (positive control group), 30.2±12.33 (young rats) and 65.88±13.46 (CA groups) mg/pg protein. The treatment group showed significantly higher tissue BDNF level compared to all group (p=0,0189). The Y-maze results show insignificant different between groups

Conclusion: In conclusion, this result showed that supplementation of CA was effective in increasing brain level of BDNF. However, it doesnt show any effect on Y-maze score."

"Penelitian ini dilakukan untuk mengetahui hubungan antara persepsi diri terhadap penuaan dan kualitas hidup lansia pada domain kesehatan fisik, psikologis, hubungan sosial, danlingkungan.Persepsi diri terhadap penuaan adalah persepsi subjektif atau sikap individu lansia mengenai penuaan yang terjadi pada diri. Kualitas hidup merupakan persepsi individu terhadap posisi kehidupannya dalam konteks budaya dan sistem nilai di mana mereka tinggal, dan kaitannya dengan tujuan, harapan, standar dan hal lainnya yang menjadi perhatian individu tersebut. Alat ukur ATOA (Attitude Toward Own Aging) untuk mengukur persepsi diri terhadap penuaan diberikan pada 94 partisipan yang berusia 60 tahun ke atas. Hasil penelitian menunjukkan korelasi positif antara persepsi diri terhadap penuaan dengan dua domain dari kualitashidup; psikologis dan lingkungan. Tidak terdapat korelasi antara persepsi diri terhadap penuaan dengan dua domain lainnya dalam kualitas hidup; yaitu kesehatan fisik dan hubungan sosial.

---

This study was conducted in order to see whether there is a correlation between self perception of aging and the quality of life in elderly in the domain of physical health, psychological, social relationships, and environment. Self perception of aging is an subjective perceptions or attitude about aging that happen in elderly individuals. The quality of life is an individual perception towards life position in cultural context, value system, and it association with purposes, expectations, standards and other matter which the individual concerned of. The Attitude Toward Own Aging (ATOA) for measuring self perception of aging was given to 94 participants aged 60 years and older. The results showed there was a positive significant correlation between self perception of aging and two out of four domains in the quality of life; psychological and the environment. There was no correlation between: self perception of aging and the other two domains in the quality of life; physical health and social relationship."

"Provides a positive perspective on adult development and aging, enhanced by multicultural and diversity coverage. This third edition includes content on younger and middle-aged adults, providing a balance between adulthood and aging."

"Summary:Written within a bio-psychosocial framework, this book covers the specific ages-stages of adult development and aging. It focuses on "positive aging" and the gains and losses people experience across adulthood."