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"Exercise and Disease Management is designed to help managed care physicians, their patients, other health care professionals, and interested readers integrate current exercise guidelines into their practices."

"Exercise-induced bronchospasm (EIB) sering dijumpai pada atlet remaja. Penelitian untuk mengetahui prevalensi EIB pada atlet remaja di Indonesia belum pernah dilakukan. Penelitian ini dilakukan untuk mengetahui prevalensi EIB pada atlet Sekolah Olahraga Ragunan dengan menggunakan tes latihan di laboratorium. Setiap atlet melakukan latihan sepeda statis (Monark, Swedia) hingga mencapai intensitas latihan minimal pada 90% laju jantung maksimal. ?Force expiratory ventilation? (FEV) diperiksa dengan menggunakan spirometri (Minato AS-PAL, Jepang) pada menit ke 0, 5, 10 dan 20 pasca latihan. Diagnosis EIB ditentukan bila terdapat penurunan FEV1 10% atau lebih dibanding nilai basal. Suhu dan kelembaban ruangan selama penelitian berkisar 28°C-31°C dan 74%-82%. Sebanyak 168 atlet mengikuti penelitian ini. Terdapat 23 atlet yang terbukti positif EIB. Persentase penderita EIB terbanyak adalah di cabang taekwondo (54,5%). Jumlah atlet yang terbukti EIB yang berasal dari cabang yang kurang asmogenik sebanyak 16 orang (70%). Terdapat 17 atlet wanita (17,5%) dan 6 atlet laki-laki (8,4%) yang menderita EIB. Ternyata, prevalensi EIB pada atlet remaja cukup besar, dan terjadi lebih banyak pada atlet wanita. Selain itu, tes latihan yang dilakukan di laboratorium dapat mendiagnosis EIB pada atlet dari cabang olahraga yang kurang mencetuskan EIB.

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AbstractExercise-induced bronchospasm (EIB) is a common condition among adolescent athletes. There has been no study examining the prevalence of EIB among adolescent athletes in Indonesia. This study aimed to get the prevalence of EIB among Ragunan Sport School athletes by laboratory exercise challenge. Subjects performed static cycle ergometer exercise (Monark, Sweden) to reach minimal workload of 90% maximal heart rate. Force expiratory ventilation (FEV1) was examined by spirometry (Minato AS-PAL, Japan) at minute 0, 5, 10 and 20 post exercise. The EIB was defined as a decline of FEV1 as much as 10% or more from baseline value. Room temperature and humidity were 28°C-31°C and 74%-82% respectively. There were 168 athletes from 12 sport types who participated in this study. Among them, 23 athletes (13.7%) were EIB positive. The highest percentage of EIB was in taekwondo (54.5%). Sixteen athletes with EIB (70%) were from less asthmogenic sports. Athletes with EIB consisted of 17 (17.5%) females and 6 (8.4%) males. In conclusion, the prevalence of EIB among adolescent athletes was moderately high, and was more prevalent in female. More over, laboratory exercise challenge could elicit EIB in less asthmogenic sport. "

"ABSTRAKOverweight dan obesitas adalah akumulasi lemak yang berlebihan yang dapat mengganggu kesehatan. Obesitas merupakan salah satu risiko untuk terjadinya gangguan kardiometabolik. Adanya polimorfisme gen UCP1, menyebabkan bervariasinya respons terhadap olahraga teratur SALI.Penelitian ini bertujuan menganalisis pengaruh senam aerobik low impact SALI pada perempuan obes abdominal yang memiliki polimorfisme gen UCP1 terhadap parameter kardiometabolik lingkar pinggang LP , kadar trigliserida TG dan penanda inflamasi Monocyte Chemmoattractant Protein-1 MCP1 .Desain penelitian adalah non randomized controlled trial. Intervensi 12 minggu terhadap 55 orang wanita obes abdominal, terdiri dari 32 orang kelompok intervensi SALI dan 23 orang kelompok kontrol. Sebelum dan sesudah program dilakukan pemeriksaan parameter kardiometabolik LP, kadar TG dan MCP1. Pemeriksaan polimorfisme -3826 A>G gen UCP1 menggunakan teknik PCR diikuti teknik RFLP.Ditemukan frekuensi genotip AA 21 orang 38,2 , genotip AG 27 49,1 dan genotip GG 7 12,7 , dengan frekuensi alel G 0,40 . Subjek dengan kadar TG ge; 130 mg/dL kelompok SALI 100 responders, Kontrol 55 , dan kelompok kadar TG < 130 mg/dL, 22 . Subjek genotip GG polimorfisme gen UCP1 dengan kadar TG ge; 130 mg/dL high responders. genotip AA low responders. Temuan ini diperkirakan terkait jumlah langkah per hari kelompok genotip GG dengan TG ge; 130 mg/dL lebih tinggi dibandingkan kelompok nonresponders.

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ABSTRACTOverweight and obesity were the accumulation of excessive fat that could harm health. Obesity was a risk for cardiometabolic disorders. The polymorhism of UCP1 gene, caused variations in response to regular exercise. This study aims to investigate the influence of low impact aerobics exercise LIAE in abdominal obes women who had the polymorphism of UCP1 gene on cardiometabolic parameters, waist circumference WC , levels of triglyceride TG and inflammatory markers Monocyte Chemoattractant Protein 1 MCP1 . The study design was non randomized controlled trial. A total of 55 women subjects moderately obes women were divided into two groups on the basis of location. Thirty two subjects of LIAE group and 23 a non LIAE control group. Subjects were not restricted in foods consumed. The study period was 12 weeks. Outcome assessments for analyses were completed at baseline and 12 weeks for cardiometabolic parameters WC, TG and MCP1. Examination of the polymorphism 3826 A G UCP1 gene using PCR technique followed by RFLP technique. The frequencies of three genotypes of 3826 A G polymorphism of UCP1 gene were AA, AG, and GG were of 21 38.2 , 27 49.1 and 7 12.7 respectively with the G allele frequency of 0.40 . Post study obtained the subjects with TG baseline TG ge 130 mg dL 100 LIAE responders group, Control 55 , while TG "

"During exercise, levels of several hormones are acutely increased in the blood. We previously reported that pre-exercise ingestion of a specific combination of amino acids (arginine, alanine, and phenylalanine; A-mix) increases fat mobilization and ketone body synthesis by increasing secretion of adrenalin and glucagon in healthy active young men. Herein, we sought to determine whether this acute hormone response could be induced upon administration of A-mix combined with exercise in patients with obesity during periods of low-intensity exercise. We performed a randomized crossover study of eleven middle-aged men with obesity without regular exercise habits, administered either A-mix (3 g/dose) or a placebo (3 g of dextrin/dose). Thirty minutes after ingestion, each subject subsequently performed workload tests on a cycle ergometer at 40% of peak oxygen consumption for 1 h. Following oral intake of A-mix, the concentration of plasma ketone bodies was significantly increased during exercise. This was accompanied by a significant increase in the area under the concentration-time curve for glucagon. Taken together, these results indicate that pre-exercise ingestion of the A-mix supplement significantly accelerated hepatic ketone body synthesis via stimulation of glucagon secretion during exercise in men with obesity."

"The health values of exercise and eating are separately established as two independent pillars for human life. However, a substantial amount of evidence shows the physiological crosstalk by which exercise might be associated with hunger and satiety, as regulated by gut hormones. A single bout of exercise tends to suppress the blood levels of orexigenic acylated ghrelin (AG) and to increase the levels of anorectic hormones like peptide YY (PYY) and gluca-gon-like peptide-1 (GLP-1). It was reported that, while sustained physical activity increases the drive to eat in the fasting state, this seems to be compensated by an improved satiety response to a meal through changes in the gut hormone systems. A few studies reported exercise-induced reductions in the neural responses to food-related cues in higher brain center networks involved in the attentional, emotional and cognitive functions. The present review introduces the latest research on the effects of various types of exercise on the neuroendocrine networks related to hunger, satiety, appetite, and responses to food-related cues, suggesting the physiological ratio¬nale for the linkage between exercise and eating in humans. Next, the possibilities of the brain science of exercise and eating for improvements in modem human health in various generational groups are discussed."

"This proceedings volume explores a range of sports-related topics, including sports science, exercise, sports engineering and technology, in contributions prepared by respected experts and presented at the 3rd International Colloquium on Sports Science, Exercise, Engineering and Technology (ICoSSEET2016). The goal of the conference was to bring together researchers and practitioners from academia and industry to address current challenges in various sports-related areas, and to establish vital new collaborations. The topics covered can be primarily divided into (1) Sports Science and Exercise, (2) Sports Engineering and Technology Application, and (3) Sports Industry and Management."