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Mahdi Jufri
Depok: Fakultas Farmasi Universitas Indonesia, 2003
T39585
UI - Tesis Membership  Universitas Indonesia Library
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"Niosomes are non ionic surfactant vesicles that have potential application in the delivery of hydrophobic or amphilic drugs. We developed proniosomes, a dry formulation using a maltodextrin as a carrier coated with non ionic surfactant, which can be used to produce niosomes within a minutes by addition of hot water
followed by agitation. A novel method is reported here for rapid preparation of proniosomes with wide range of surfactant loading. Maltodextrin DE 5-10 was hidrolyzed from tapioca starch using Thermamyl L 120 da Novo at 85o C. The result from SEM analyses shown that proniosomes appear very similar to the maltodextrin, but the surface was more smooth. Niosome suspensions which was observed under the optical microscopy and particle size analyzer were evaluated as
drug carrier using ibuprofen as a model. The result provide an indication of maltodextrin DE 5-10 from tapioca starch are potentialy carrier in the proniosome preparation which can be used for producing niosomes. "
[Fakultas Farmasi Universitas Indonesia, Universitas Indonesia], 2004
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Artikel Jurnal  Universitas Indonesia Library
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Juheini Amin
"Maltodextrin utilization of topioca strarch as a film coating on amoxyllin tablet: Maltodextrin is produced by hydrolized of strach used enzyme or acid, that reduced the amount of sugar 20 maximal .In this research,maltodextrin DE 5 to 10 was made from tapioca starch (Manihot utillissima Pohl) by using Temamyl L-120 Novo enzyme as a-amylase at 85 oC for 65 minute.Maltodextrin De 5 to 10 with particlesize 60 mesh (250 um) was used as fil coating on amoxycillin tablet in order to reduce a bad smell .AS a standard of coating was used pharmacoad 645w. The coating tables were evaluated according to Fi III an IV included visual test. Weight uniformity, size uniformity, hradness, friability,desintegration time, dissolution test and smell test.The result of this research showed that maltodextrin DE 5-10 from tapioca starch fulfill the terms above. The best formula is maltodextrin 10 %, PEG 400 5% and Na Alginat 5% from polymer weight."
Depok: Universitas Indonesia, 2002
SAIN-7-1-2002-23
Artikel Jurnal  Universitas Indonesia Library
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