Hasil Pencarian  ::  Simpan CSV :: Kembali

"Deteksi dini osteoporosis perlu dilakukan untuk mencegah kegagalan perawatan gigi tiruan. Quantitative Ultrasound (QUS) selama ini dipakai secara luas untuk skrining osteoporosis. Kuesioner Postur-P juga digunakan untuk skrining osteoporosis. Penelitian ini bertujuan untuk menganalisis sensitivitas dan spesifisitas kuesioner Postur-P terhadap QUS dalam penilaian densitas tulang perempuan pascamenopause. Penelitian ini merupakan uji diagnostik. Pengambilan data dilakukan lewat wawancara menggunakan kuesioner Postur-P dan pengukuran densitas tulang menggunakan alat QUS. Hasil penelitian menunjukkan sensitivitas dan spesifisitas kuesioner Postur-P terhadap QUS cukup baik dengan persentase masing-masing sebesar 77,23% dan 75% sehingga kuesioner Postur-P dapat dijadikan sebagai pengganti QUS dalam melakukan skrining osteoporosis.

---

Early detection of osteoporosis needs to be done to prevent the failure of denture treatment. Quantitative Ultrasound (QUS) is widely used for osteoporosis screening. So is Postur-P questionnaire. This research was done to analyze the sensitivity and specificity of the Postur-P questionnaire towards QUS in assessing postmenopausal women bone density. This study was a diagnostic test. Data were collected through interviews using Postur-P questionnaire and bone density was measured with QUS. The results of this study show that the sensitivity and specificity of the Postur-P questionnaire towards QUS are quite good with the value of 77.23% and 75% therefore questionnaire Postur-P can be considered to replace QUS in osteoporosis screening."

"Osteoporosis is a silent disease, i.e. the disease will progress without symptoms or pain until bones start to break. Densitometry examinations to diagnose osteoporosis is relatively expensive for most people in Indonesia. Kusdhany et al have produced a mandibular density index specific for Deutero-Malay postmenopausal women (POSTUR-P). This index can be used to predict osteoporosis risk in mandibular and other bones. The objective of this research was to try out POSTUR-P before using it in the community. The study was a diagnostic test, on 31 Teratai clinic postmenopausal patients of Ciptomangunkusumo Hospital between 50-75 years of age from June to October 2014 and fulfilling inclusion criteria. Densitometry on lumbal and femur bones was used as a gold standard. The result of this study showed that POSTUR-P has high sensitivity and moderate specificity, and appears to be a good screening tool to indicate osteoporosis cases."

"ABSTRAKMiR-21 diketahui berperan dalam proliferasi dan diferensiasi osteoklas, namun peran ekspresi miR-21 serum pada osteoporosis masih belum jelas. Penelitian sebelumnya mendapatkan bahwa ekspresi miR-21 serum berkorelasi positif dengan densitas mineral tulang pada penderita osteoporosis pascamenopause, tetapi penelitian tersebut tidak menganalisis faktor-faktor lainnya yang terlibat dalam osteoporosis pascamenopause.Penelitian ini bertujuan untuk mengetahui peran ekspresi miR-21 serum, konsentrasi RANKL, OPG, TGF- ? 1, sklerostin, rasio RANKL/OPG, kalsium serum dan aktivitas fisis terhadap densitas mineral tulang belakang pada perempuan pascamenopause hipoestrogenik dengan osteoporosis dibandingkan dengan tanpa osteoporosis, dengan point of interest pada ekspresi miR-21 serum.Penelitian ini dilakukan dengan disain uji potong lintang komparatif, di RSUD Ulin Banjarmasin, pada bulan Agustus 2015 sampai Juli 2016. Subjek dibagi menjadi 2 kelompok yaitu perempuan pascamenopause hipoestrogenik dengan osteoporosis dan tanpa osteoporosis. Pengambilan sampel dilakukan dengan metode consecutive. Pemeriksaan ekspresi miR-21 serum menggunakan metode absolute quantification real-time PCR. Analisis statistik menggunakan uji korelasi Spearman, Mann-Whitney U test dan regresi linear berganda.Subjek dibagi menjadi 2 kelompok yaitu perempuan pascamenopause hipoestrogenik dengan osteoporosis PMOP dan tanpa osteoporosis PMNOP masing-masing sebanyak 60 subjek. Median ekspresi miR-21 serum pada PMOP lebih tinggi secara bermakna dibandingkan dan PMNOP p = 0,001 . Ekspresi miR-21 serum, RANKL, rasio RANKL/OPG dan aktivitas fisis berkorelasi bermakna dengan nilai BMD pada PMOP. Aktivitas fisis sedang berkorelasi negatif bermakna dengan ekspresi miR-21 serum pada PMOP dan PMNOP. Analisis regresi linear berganda menggunakan metode backward stepwise mendapatkan persamaan regresi linear: BMD = 1,373 - 0,085 Ln.miR-21 - 0,176 Log 10.RANKL R2 = 52,5 .Simpulan. Ekspresi miR-21 serum pada perempuan pascamenopsuse hipoestrogenik dengan osteoporosis terbukti lebih tinggi dibandingkan dengan tanpa osteoporosis. Ekspresi miR-21 serum terbukti memberikan pengaruh negatif terhadap nilai BMD tulang belakang pada perempuan pascamenopause hipoestrogenik dengan osteoporosis sebesar 8,5 , dengan persamaan regresi linear BMD = 1,373 - 0,085 Ln.miR-21 - 0,176 Log10.RANKL. Persamaan ini dapat menjelaskan nilai BMD tulang belakang sebesar 52,5 . Kata kunci: BMD, miR-21 serum, Osteoporosis, Pascamenopause

---

ABSTRACTMiR-21 is known to play a role in osteoclast proliferation and differentiation, but the role of serum miR-21 expression in osteoporosis remains unclear. Previous research found that serum miR-21 expression was positively correlated with bone mineral density in postmenopausal osteoporosis patients, but the study did not analyze other factors involved in postmenopausal osteoporosis.This study aimed to determine the role of serum miR-21 expression, concentration of RANKL, OPG, TGF- ? 1, sclerostin and serum calcium, RANKL/OPG ratio, and physical activity on bone mineral density of spine in hypoestrogenic postmenopausal women with osteoporosis compared to no osteoporosis, with point of interest on the expression of serum miR-21.This study was conducted by comparative cross sectional design, conducted at Ulin General Hospital Banjarmasin, from August 2015 until July 2016. The subjects were divided into 2 groups of hypoestrogenic postmenopausal women with osteoporosis and without osteoporosis. Sampling was done by consecutive method. Examination of serum miR-21 expression using absolute quantification real-time PCR method. Statistical analysis using Spearman correlation test, Mann-Whitney U test and multiple linear regression.The subjects were divided into 2 groups of hypoestrogenic postmenopausal women with osteoporosis PMOP and without osteoporosis PMNOP each as many as 60 people. Median of serum miR-21 expression at PMOP group was significantly higher compared to PMNOP group p = 0.001 . Serum miR-21 expression, RANKL, RANKL/OPG ratio and physical activity were significantly correlated with BMD values ? ? ? ?in PMOP group. Moderate physical activity was significantly negative correlated with serum miR-21 expression. Multiple linear regression multivariate analysis using backward stepwise method obtained linear regression equation BMD = 1,373 - 0,085 Ln.miR-21 - 0,176 Log10.RANKL R2 = 52,5 .Conclusion. Serum miR-21 expression in hypoestrogenic postmenopausal women with osteoporosis has been shown to be higher compared with no osteoporosis. Serum miR-21 expression proved to have a negative effect on spinal BMD values in hypoestrogenic postmenopausal women with osteoporosis of 8.5 , with linear regression equation BMD = 1.373 - 0.085 Ln.miR-21 - 0.176 Log10.RANKL. This equation can explain the value of spinal BMD by 52.5 . Keywords: BMD, Osteoporosis, postmenopausal, serum miR-21 "

"Latar belakang: Subepidermal low echogenic band (SLEB) adalah gambaran USG berupa area hipoekhoik pada lapisan dermis, tepatnya subepidermal, yang merupakan suatu proses elastosis sebagai penanda dari photoaging.Tujuan: Menilai perbedaan rasio ketebalan SLEB dengan dermis antara kelompok perempuan pra dan pascamenopause dengan menggunakan USG general purpose frekuensi 18 MHz.Metode: Penelitian ini merupakan studi potong lintang komparatif menggunakan data primer dan data sekunder. Data primer diperoleh melalui pengukuran langsung di pipi kanan dan kiri dengan menggunakan USG general purpose frekuensi 18 MHz. Data sekunder diperoleh dari penelitian sebelumnya.Hasil: Rerata usia subjek pramenopause sebesar 29,6 tahun dan rerata usia subjek pascamenopause sebesar 55,7 tahun. Rerata tebal dermis dan rerata tebal SLEB didapatkan lebih tebal pada kelompok pramenopause dibandingkan kelompok pascamenopause. Rasio SLEB – dermis pada kelompok pramenopause didapatkan lebih tebal dibandingkan kelompok pascamenopause.Kesimpulan: Rasio tebal SLEB terhadap tebal dermis pada kelompok pramenopause didapatkan lebih tebal dibandingkan pada kelompok pascamenopause. USG general purpose dapat digunakan dalam menilai tebal dermis dan tebal SLEB, namun diperlukan studi lebih lanjut dalam menilai faktor – faktor lain yang mempengaruhi rasio tebal SLEB terhadap tebal dermis.

---

Background: Subepidermal low echogenic band (SLEB) is an ultrasound image in the form of a hypoechoic area in the dermis layer – subepidermal, to be precise, which is an 2 elastotic process as a marker of photoaging. Objective: Assessing difference in ratio of SLEB to dermis thickness between the premenopausal and postmenopausal groups using the 18 MHz general-purpose ultrasound frequency.

Method: This research is a comparative cross-sectional stuy using primary data and secondary data. Primary data were obtained through direct measurements on the right and left cheeks using general purpose ultrasound with a frequency of 18 MHz. Secondary data was obtained from previous studies.

Result: The mean age of premenopausal subjects was 29.6 years and the average age of postmenopausal subjects was 55.7 years. The mean dermis thickness and mean SLEB thickness were found to be thicker in the premenopausal group than the postmenopausal group. The SLEB – dermis ratio in the premenopausal group was found to be thicker than the postmenopausal group.

Conclusion: The ratio of SLEB thickness to dermis thickness in the premenopausal group was found to be thicker than in the postmenopausal group. General purpose ultrasound can be used in assessing dermis thickness and SLEB thickness, but further studies are needed in assessing other factors that affect the ratio of SLEB thickness to dermal thickness."

"Mamografi merupakan pemeriksaan baku emas dan merupakan modalitas satu-satunya untuk skrining payudara perempuan. Namun efektivitas mamografi menurun terutama pada payudara berdensitas padat. Handheld ultrasonography (HHUS) sering diperlukan sebagai pelengkap mamografi dan dapat meningkatkan sensitivitas dan spesifisitas untuk deteksi kanker payudara berdensitas padat. Automated breast ultrasound (ABUS) merupakan modalitas relatif baru dengan beberapa kelebihan dibandingkan dengan HHUS antara lain reproducible, variabilitas yang rendah, waktu akuisisi lebih singkat dan konsisten, serta ukuran transduser yang lebar sehingga mencakup payudara lebih menyeluruh dan dapat melakukan karakterisasi lesi yang ukurannya melebihi lebar transduser HHUS dengan lebih baik. Saat ini penggunaan ABUS belum merata di rumah sakit di Indonesia, dan penelitian mengenai ABUS masih terbatas, sehingga perlu dilakukan penelitian mengenai ABUS dibandingkan dengan modalitas lain secara lebih obyektif. Tujuan : Penelitian ini bertujuan untuk mengetahui kesesuaian temuan, morfologis, dan lokasi lesi di payudara berdasarkan densitas mamografi dan HHUS dengan densitas mamografi dan ABUS. Metode: Dilakukan pemeriksaan payudara menggunakan mamografi, HHUS GE tipe Logic S8 dengan transduser linear 7-12 MHz, dan ABUS GE Invenia dengan transduser konkaf linear 6-12 MHz. Seluruh pemeriksaan HHUS dan ABUS dilakukan sendiri oleh peneliti di Departemen Radiologi RSCM, dan dikonfirmasi oleh Dokter Spesialis Radiologi konsultan payudara bersertifikasi ABUS untuk menentukan ada atau tidaknya lesi, morfologis, dan lokasi lesi. Kesesuaian hasil pemeriksaan mamografi-ABUS dan mamografi HHUS dianalisis menggunakan uji Mc Nemar. Hasil: Terdapat 30 subyek penelitian dan diperoleh 48 sampel payudara, dengan rentang usia 36-66 tahun (rerata ± SD 51,4 ± 8,5 tahun). Dalam menentukan ada tidaknya lesi, pemeriksaan mamografi- HHUS dan mamografi-ABUS memiliki kesesuaian dengan level sedang (moderate agreement), nilai Kappa 0,43 dan 0,49 (p 0,002 dan p 0,001); dalam menentukan morfologis lesi memiliki kesesuaian dengan level sedang (moderate agreement) dengan nilai Kappa 0,51 dan 0,43 (p 0,000 dan 0,000); serta dalam menentukan lokasi lesi memiliki kesesuaian dengan level fair agreement dengan nilai Kappa 0,37 dan 0,36 (p 0,000 dan 0,000). Simpulan: Kombinasi mamografi-HHUS memiliki kesesuaian dengan level relatif setara dalam menentukan ada tidaknya lesi dan lokasi lesi, namun sedikit lebih tinggi dalam menilai morfologis lesi dibandingkan dengan kombinasi mamografi- ABUS.

---

Background: Mammography is the gold standard and well known to be a powerful screening tool in the detection of breast cancer. However its sensitivity is reduced in women with dense breasts. Additionally, women with dense breasts have an increased risk of developing breast cancer while mammography has a lower sensitivity. Handheld ultrasonography (HHUS) is often needed as a adjunction to mammography, can increase sensitivity and specificity for detection of cancer in dense breast breasts. Automated breast ultrasound (ABUS) is a relative new modality with several advantages compared to HHUS including reproducible, low variability, shorter and consistent acquisition time, and a wide transducer size that covers the breast more thoroughly and can characterize lesions whose size exceeds the width of the transducer HHUS better. At present the use of ABUS is not evenly distributed in hospitals in Indonesia, and research on ABUS is still limited, so it is necessary to conduct research on ABUS compared to other modalities more objectively. Objective : This study aims to determine the alternative selection of HHUS and ABUS examination to detect abnormalities in the breast based on mammographic density. Method: Breast examination using mammography, HHUS GE Logic S8 with 7-12 MHz linear transducer, and GE Invenia ABUS with 6-12 MHz linear concave transducer. All HHUS and ABUS examinations are carried out solely by researchers in the Radiology Department of the RSCM, and are confirmed by an ABUS certified breast consultant radiologist to determine the presence, morphology, and location of the lesion. The suitability of ABUS mammography and HHUS mammography results were analyzed using the Mc Nemar test. Result: There were 30 subjects and 48 breast samples were obtained, with an age range of 36-66 years (mean ± SD 51.4 ± 8.5 years). In determining the presence or absence of lesions, examination of mammography- HHUS and mammography-ABUS is in accordance with moderate agreement and Kappa values 0.43 and 0.49 (p 0.002 and p 0.001); in determining the morphology of the lesion is in accordance with moderate agreement and Kappa value 0.51 and 0.43 (p 0,000 and 0,000); and in determining the location of the lesion is in accordance with fair agreement and Kappa values of 0.37 and 0.36 (p 0,000 and 0,000). Conclusion : The mammographic-HHUS combination is compatible with a relatively equal level in determining the presence or absence of the lesion and location of the lesion, but is slightly higher in assessing the morphology of the lesion compared with the mammographic- ABUS combination. "

"Studi tentang efek kulit buah delima (Punica granatum L.) yang diketahui mengandung asam elagat, telah diteliti meningkatkan kadar osteoblas, kalsium, dan fosfor pada tikus ovariektomi, namun belum diketahui apakah memberikan efek pada wanita pascamenopause. Penelitian ini bertujuan mengevaluasi apakah sediaan komersil kapsul ekstrak kulit buah delima memiliki efek terhadap modulasi petanda pembentukan tulang dan kualitas tulang pada wanita pascamenopause. Penelitian ini merupakan uji klinik pendahuluan fase 1 dengan desain paralel, acak, berpembanding plasebo, dan tersamar ganda, dengan 30 subyek. Subyek dirandomisasi untuk mendapatkan sediaan komersil kapsul ekstrak etanol kulit buah delima 2 x 1100 mg/ hari atau plasebo selama 8 minggu. Sebelum dan sesudah perlakuan, diperiksa kadar osteokalsin, kalsium, dan fosfor. Hasil penelitian ini menunjukkan bahwa pemberian sediaan cenderung menghambat laju perombakan tulang dengan menghambat peningkatan kadar osteokalsin, sebagai salah satu petanda laju perombakan tulang (4,129±5,66 ng/ml pada kelompok plasebo, 1,79±5,04 ng/ml pada kelompok punica, p=0,245), tidak mempengaruhi kadar kalsium (9,13±0,36 mg/dl pada kelompok plasebo, 9,21±0,39 mg/dl pada kelompok punica, p=0,379), dan tidak mempengaruhi kadar fosfor (3,93±0,38 mg/dl pada kelompok plasebo, 4,12±0,41 mg/dl pada kelompok punica, p=0,138). Pemberian sediaan tidak mempengaruhi fungsi hati dan fungsi ginjal, serta dapat ditoleransi dengan baik. Kesimpulan penelitian ini adalah sediaan berpotensi menghambat peningkatan petanda pembentukan tulang dalam darah dan meningkatkan kualitas tulang wanita pascamenopause, serta aman.

---

Studies of pomegranate peel (Punica granatum L.), which contain ellagic acid, was shown to increase osteoblast, calcium, and phosphorus in ovariectomized rats. The effect of the pomegranate peel extracts on postmenopausal women was not known. This study was aimed to evaluate the effect of commercial capsules of pomegranate peel ethanol extracts in the modulation of bone formation and bone quality markers in postmenopausal women. This study is a pilot study of phase 1 clinical trial using parallel, randomized, double-blind, and placebo controlled design, with 30 subjects. Subjects were randomized to receive commercial capsules of pomegranate peel ethanol extracts 2 x 1100 mg/ day or placebo, for 8 weeks. Levels of osteocalcin, calcium, and phosphorus were examined before and after treatment.

This study showed that administration of the commercial capsules in postmenopausal women tends to reduce blood osteocalcin level (4,129±5,66 ng/ml on placebo group and 1,79±5,04 ng/ml on punica group, p=0,245), does not influence on blood calcium level (9,13±0,36 mg/dl placebo group and 9,21±0,39 mg/dl punica group, p=0,379), does not influence on blood phosphorus level (3,93±0,38 mg/dl placebo group and 4,12±0,41 mg/dl on punica group, p=0,138), does not affect the function of liver and kidney, and was well tolerated. In conclusion, this study demonstrated that the commercial capsules potentially reduce marker of bone formation serum level, increase bone quality on postmenopausal women, and safety."

"Latar Belakang. Densitas tulang yang rendah pada usia lanjut antara lain dipengaruhi oleh gangguan produksi dan metabolisme vitamin D, konsumsi alkohol, aktivitas fisik yang kurang, indeks massa tubuh (IMT) yang rendah, merokok yang berlebihan dan asupan kaisium yang rendah. Asupan kalsium, indeks massa tubuh dan kapasitas fisik diketahui berpengaruh pada densitas massa tulang.Korelasi antara asupan kaisium, IMT dan kapasitas fisik dengan densitas massa tulang masih kontroversi dan di Indonesia masih belum banyak diteliti khususnya di Panti Werda.Tujuan. Mengetahui korelasi asupan kalsium, IMT, kapasitas fisik dengan densitas massa tulang lumbal dan femur wanita usia lanjut serta gambaran densitas massa tulang lumbal dan femur, jumlah asupan kalsium, gambaran IMT,dan kapasitas fisik wanita usia lanjut di Panti Werda.Metodalogi. Studi potong lintang dilakukan pada wanita usia lanjut (?60 tahun) di Panti Werda. Subyek penelitian didapat dengan metode cluster random sampling dan yang sesuai dengan kriteria inklusi. Kriteria inklusinya adalah berusia 60 tahun atau lebih, jenis keiamin perempuan, masih dapat mandiri (ADL Barthel >16), dan bersedia ikut daiam penelitian. Dilakukan uji korelasi Pearson dengan aiternatif uji korelasi Spearman jika sebaran data tidak normal untuk mengetahui korelasi antara asupan kalsium, IMT dan kapasitas fisik dengan densitas massa tulang lumbal dan femur.Hasil. Selama periode Maret-Mei 2005 dilakukan penelitian terhadap 51 wanita usia lanjut di 2 Panti Werda Jakarta dan Bekasi. Median usia 70,5 (7,5) tahun, median asupan kalsium 283 gram/hari, IMT 22,28 (4,2) kg/m2 dan kapasitas fisik sebesar 4,8(1,6) Metz. Sedangkan rerata densitas tulang lumbal 0,842(0,I64) gramlcm2 dan densitas tulang femur 0,652(0,097) grarnlcm2. Didapatkan korelasi bermakna antara IMT dengan densitas massa tulang lumbal dan femur (r = 0,677 ; p = 0,000 dan r = 0, 508 ; p = 0,000), dan tidak didapatkan korelasi antara asupan kalsium dengan densitas massa tulang lumbal dan femur (r = 0,146 ; p = 0,308 dan r = 0,096 ; p = 0,501) dan kapasitas fisik dengan densitas massa tulang lumbal dan femur (r=0,016; p=0,913 dan r=0,143 dan nilai p=0,318).Kesimpulan. Didapatkan korelasi antara IMT dengan densitas massa tulang lumbal dan femur sedangkan korelasi antara asupan kalsium dan kapasitas fisik dengan densitas tulang lumbal dan femur wanita usia lanjut di Panti Werda belum dapat dibuktikan. Prevalensi densitas tulang lumbal dan femur wanita usia lanjut di panti werda Jakarta dan Bekasi berkurang sebesar 100% dan 99,8%., asupan kalsiumnya rendah, indeks massa tubuh normal dan kapasitas fisik tingkat menengah.

---

Backgrounds

Low bone density in elderly may be caused by decreased production and metabolic dysfunction of vitamin D metabolism, alcohol consumption, decreased physical activity, low BMI, excessive smoking, and low calcium intake. Calcium intake, BMI and physical capacity had already been known to have influence on BMD. The correlation between calcium intake, BMI and physical capacity with BMD is still controversial and there is not much data in Indonesia regarding of it especially in elderly population.

Objective

To investigate the correlation between calcium intakes, body mass index and physical capacity with lumbar and femoral bone mass density of elderly women in nursing homes.

Methods

A cross sectional study was conducted in elderly women in nursing homes. Subjects were obtained by cluster random sampling method and fulfilled inclusion criteria Inclusion criteria were age more than 60 years old, female, and Barthel index >16. We have done Pearson correlation test with Spearman test as alternative if data distribution was not normal.

Result

A cross sectional study was conducted on 51 elderly women in 2 nursing homes in Bekasi between March and May 2005. Median age was 70.5 years, median calcium intake 283 gram/day, BMI 22.28 ± 42 kg/m2 and physical capacity 4.8 ± 1,6 metz. Mean of lumbar BMD was 0.842 ± 0.164 gram/cm2 and mean femoral BMD was 0.652 ± 0.097 gram/cm2. We found significant correlation between BMI and lumbar and femoral BMD (r).677;p).000 and r =508; p=0.000) and there was no correlation between calcium intake and lumbar and femoral BMD (rO.146;p-0.000 and r=0.096;p=0.50 l ). There were no correlation found between physical capacity and lumbar and femoral BMD (r).016;p 0.913 and r-0.143 and p O.318).

Conclusion

This study showed correlation between BMI and lumbar and femoral BMD. We found no correlation between calcium intake and physical capacity with femoral and lumbar BMD in elderly women in nursing homes in Jakarta and Bekasi. Prevalensi of lumbar BMD and femoral BMD of elderly women in nursing homes in Jakarta was decreased (100% and 99,8%).Calcium intake was low, BMI was normal and physical capacity was moderate level."

"ABSTRAKIn prosthodontics, mandibular bone density plays an important role in the success of treatment. Generally, the aging process will be accompanied by decreasing mandibular bone density. This is more obvious in post menopausal women with low or absent estrogen production. Relationship between mandibular bone density and bone density in other parts of the body is still debatable. The aim of this study was to evaluate this relationship. Periapical radiographs and bone densitographs of 114 post menopausal women were evaluated in a cross sectional study. The results showed a relationship between age and amount of teeth present with decreasing mandibular bone density, and a significant correlation between mandibular bone density and lumbal or femur bone density."

"Untuk mengetahui pola densitas mineral tulang pada wanita pasca menopause dilakukan penelitian secara retrospektif terhadap 40 wanita pasca menopause dengan menggunakan alat Dexa pada tulang L2 – L4. Didapatkan hasil dengan akurasi formula survey 15%: rerata usia menopause 53,25 tahun, 30 % densitas mineral tulang normal, 52,5 % osteopenia & 17,5 % osteoporosis. Pada penelitian ini juga didapatkan ada hubungan yang kuat ( r = 0,547 ) & sangat bermakna ( p = 0,000 ) antara tinggi badan dengan densitas mineral tulang, didapatkan hubungan yang cukup ( r = 0,315 ) & bermakna ( p = 0,047 ) antara berat badan dengan densitas mineral tulang, demikian pula hubungan yang cukup ( r = - 0,301 ) & bermakna ( p = 0,059 ) antara lama menopause dengan densitas mineral tulang, serta tidak didapatkan hubungan antara usia ( r = 0,119 ) maupun Indeks Masa Tubuh ( IMT ) ( r = 0,086 ) dengan densitas mineral tulang. (Med J Indones 2004; 13: 31-9)

---

To identify the pattern of bone mineral density in postmenopausal women through retrospective study in 40 postmenopausal women using Dexa instrument in bones (L2 - L4). Results with 15% of survey formula accuracy were found: mean of menopausal age was 53.25 years, normal bone mineral density 30%, osteopenia 52.5%, and osteoporosis 17.5%. A very strong relationship (r=0.547) and a significant relationship (p=0.000) between body height and bone mineral density were found in this study, and there was a moderate (r=0.315) and significant (p= 0.047) relationship between body weight and bone mineral density, and likewise there was a moderate (r=-0.301) and significant (p=0.059) relationship between duration of menopause and bone mineral density. By contrast, no relationship was found between age (r=0.119) and Body Mass Index (BMI) (r=0.086) and bone mineral density. (Med J Indones 2004; 13: 31-9)"