Hasil Pencarian  ::  Simpan CSV :: Kembali

"In Quantitative Modeling in Toxicology leading experts outline the current state of knowledge on the modeling of dose, tissue interactions and tissue responses. Each chapter describes the mathematical foundation, parameter estimation, challenges and perspectives for development, along with the presentation of a modeling template. Additionally, tools and approaches for conducting uncertainty, sensitivity and variability analyses in these models are described."

"This book aimed to bring the reader up to date on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies."

"This book, written by two outstanding scientists in the field, describes the basic principles of toxic mechanisms and organ toxicity, providing detailed information on specific mechanisms or chemicals for exemplification. The goal is to provide sufficient information that the reader becomes familiar with the basic concepts in toxicology to enable him or her to understand the basic principles in toxicology and to evaluate the risks at given exposures. With this basic understanding the reader also will be able to critically evaluate the available information on a chemical and to identify data gaps."

"This first comprehensive treatment of the subject for more than a decade includes the latest research on nanoparticle toxicology. The practical handbook addresses all areas where toxic mixtures are encountered, from environmental via occupational to medical settings, giving special consideration to air and water, and to the specific requirements for study design in mixture toxicology. While no extensive prior knowledge or toxicological experience is required, the practice-oriented case studies and examples in the second part make this the ideal companion for the professional toxicologist in industry or healthcare institutions with little time for academic study."

"The book shows validation of precipitation modeling against observations and derives a set of diagnostic precipitation equations. The book provides detailed discussions of the applications of precipitation equations to the examination of effects of sea surface temperature, vertical wind shear, radiation, and ice clouds on torrential rainfall processes in the tropics and mid-latitudes, and to the studies of sensitivity of precipitation modeling to uncertainty of the initial conditions and to the estimate of precipitation efficiency. "

"Tujuan: menilai prevalensi katarak terinduksi radiasi, serta menghubungkannyadengan dosis paparan radiasi dan penggunaan perlengkapan proteksi radiasi.Metode: Studi potong lintang dan studi kasus-kontrol. Seratus delapan puluh subyekberpartisipasi dalam penelitian. Prevalensi katarak terinduksi radiasi dinilaimenggunakan analisis Scheimpflug pada alat Pentacam®-Oculus. Dosis paparanradiasi kumulatif dan penggunaan perlengkapan proteksi radiasi pada subyekdiidentifikasi melalui kuesioner dan personal dosimeter.Hasil: Prevalensi katarak terinduksi radiasi sebanyak 16.7%. Median dosis radiasikumulatif berdasarkan kuesioner menunjukkan median 0,8 (0.1- 35.6) Gy. Hubungankorelasi positif didapatkan antara dosis radiasi kumulatif dengan densitas lensa (RSpearman= 0.64). Sebanyak 83.9% subyek menggunakan tabir pada 71-100% masakerjanya, tetapi mayoritas subyek penelitian (40.6%), tidak menggunakan kacamatapelindung. Peningkatan risiko katarak terinduksi radiasi meningkat secara bermaknaseiring dengan kepatuhan penggunaan proteksi radiasi yang kurang. Subyek denganproteksi tabir radiasi 31-50% dari masa kerjanya meningkatkan risiko katarak 10.80kali lipat (IK 95% 1.05-111.49, p=0.044). Sementara itu, kelompok proteksi tabirradiasi 51-70% meningkatkan risiko katarak 8.64 kali lipat (p=0.001). Subyek yangtidak memakai kacamata pelindung memiliki OR 164.3 (IK 95% 19.81-1363)dibandingkan dengan kelompok pengguna kacamata pelindung.Kesimpulan: Katarak terinduksi radiasi pada pekerja radiasi bidang kardiologiintervensi tergantung pada dosis paparan radiasi dan penggunaan proteksi radiasi.Oleh karena itu, kepatuhan pekerja radiasi perlu ditingkatkan sesuai ketentuanproteksi radiasi.

---

Objectives: to determine the prevalence of radiation-induced cataract and correlatewith radiation exposure dose and radiation protection use among radiation workers ofinterventional cardiology.Methods: A cross-sectional and retrospective case-control study. One hundred andeighty subjects were included. Prevalence of radiation-induced cataract was assessedusing Scheimpflug analysis on the Pentacam®-Oculus. Individual cumulativeradiation exposure dose and radiation protection use of subjects were identified fromquestionnaire and personal dosimeter.Results: The prevalence of radiation-induced cataract was 16.7%. Median cumulativeradiation dose was 0.8 (0.1-35.6) Gy. A positive correlation was found betweencumulative radiation dose and lens density (RSpearman=0.64). This study showed that83.9% of subjects used ceiling-suspended shield in 71-100% of their working period,however the majority of subjects (40.6%) did not wear protective eyewear.Statistically significant increasing risk of cataract was found along with unresponsiveuse of radiation protection. The subjects using ceiling-suspended shield in 31-50% oftheir working period were increasing their cataract risk by 10.80 times (95% CI 1.05-111.49, p=0.044). Meanwhile, the subjects using protective eyewear in 51-70% oftheir working period were increasing their cataract risk by 8.64 times (p=0.001).Subjects who did not wear protective eyewear had an OR 164.3 (95% CI 19.81-1363)compared to those who wore protective eyewear.Conclusion: Radiation-induced cataract among radiation workers of interventionalcardiology was depend on radiation exposure dose and radiation protection.Therefore, the compliance of radiation safety recommendation should be improved."