Ditemukan 3767 dokumen yang sesuai dengan query
Weinheim: John Wiley & Sons, 2013
660.29 EMU
Buku Teks SO Universitas Indonesia Library
"Bridging academic research and industrial applications, this is the first modern approach to relate fundamental research to the applied science of colloids. This text examines the role of colloid and interface science in pharmacy, as well as pharmaceutical formulations and drug delivery. It then goes on to treat pharmaceutical suspensions and emulsions, including multiple emulsions, as well as liposomes and the role of nanotechnology in drug delivery. A final section is devoted to the hot topic of stem cell research."
Weinheim, Germany: Wiley-VCH, 2007
e20395871
eBooks Universitas Indonesia Library
Vold, Robert D.
Reading, MA: Addison-Wesley, 1983
541.33 VOL c
Buku Teks SO Universitas Indonesia Library
Kurniawan Pambudi
"Minyak biji jinten hitam yang dikenal memiliki khasiat sebagai obat herbal mempunyai bau dan rasa yang khas. Oleh karena itu dibuat sediaan emulsi minyak biji jinten hitam tipe O/W. Penelitian ini bertujuan untuk menutupi bau dan rasa serta mengetahui stabilitas sediaan emulsi yang baik dari esktraksi Jinten hitam (Nigella sativa Linn) dengan emulgator Span 80 dan Tween 80 dengan variasi konsentrasi 20%,50% dan 70 % dari jumlah minyak biji jinten hitam dalam sediaan. Evaluasi yang dilakukan meliputi volume sedimentasi, viskositas, ukuran partikel, uji stabilitas fisik, pH, dan penetapan kadar. Dari hasil pengujian, emulsi dengan konsentrasi emulgator 70% memiliki stabilitas yang baik. Formula emulsi tersebut telah dapat memperbaiki aroma dan rasa minyak biji jinten hitam, tetapi belum untuk penampilannya.
The black seeds cumin oil known to have efficacy as medicinal herbs having peculiar odor and taste. Hence preparation made emulsify oils black seeds cumin type O/W. This study aims to cover odor and taste and knowing stability emulsion preparation of black cumin esktract (nigella sativa linn) with emulgator span 80 and tween concentration with variations 20%, 50% and 70% of the oil of cumin black seeds in preparation. Evaluation volume discontinuous, conducted include viscosity, size of particles, the physical stability pH levels and determination. The evaluation of emulsion with concentration emulgator 70% having good stability. This formula could prove the odor and taste of black seeds cumin oil."
Depok: Fakultas Farmasi Universitas Indonesia, 2013
S45435
UI - Skripsi Membership Universitas Indonesia Library
"UK Colloids 2011, the first multi-day conference on the topic of colloid science held in the UK for many years, jointly organized by the RSC Colloid and Interface Science Group and the SCI Colloid and Surface Science Group. This title collects together a selection of 20 papers, mostly presented during the Conferenc"
Berlin: Springer, 2012
e20406098
eBooks Universitas Indonesia Library
Suesti Devi Purnamasari
"Natrium diklofenak adalah obat antiinflamasi yang dapat mengiritasi lambung dan mengalami metabolisme lintas pertama. Untuk mengatasi hal ini, natrium diklofenak dibuat dalam bentuk sediaan transdermal. Dalam penelitian ini dibuat dua bentuk sediaan transdermal yaitu emulsi dan mikroemulsi, guna membandingkan perbedaan jumlah kumulatif natrium diklofenak yang terpenetrasi. Formulasi sediaan emulsi dan mikroemulsi menggunakan Virgin Coconut Oil sebagai fase minyak dengan natrium diklofenak sebagai model obat. Daya penetrasi sediaan emulsi dan mikroemulsi melalui kulit diuji secara in-vitro dengan alat sel difusi Franz menggunakan membran abdomen tikus galur Spraque-Dawley. Jumlah kumulatif natrium dikofenak yang terpenetrasi selama 8 jam dari sediaan emulsi dan mikroemulsi berturut-turut adalah 911,00 ± 3,67 μg/cm2 dan 445,41 ± 6,14 μg/cm2. Fluks natrium diklofenak pada sediaan emulsi dan mikroemulsi berturut-turut adalah 107,42 ± 1,25 μg/cm2.jam dan 49,29 ± 0,63 μg/cm2.jam. Persentase kumulatif jumlah natrium diklofenak dalam sediaan emulsi dan mikroemulsi yang terpenetrasi berturut-turut adalah 15,68 ± 1,17 % dan 8,80 ± 0,12 %. Selain itu juga dilakukan uji stabilitas fisik meliputi cycling test, uji sentrifugasi dan pengamatan pada penyimpanan selama 8 minggu pada suhu kamar (28° ± 2°C), suhu rendah (4° ± 2°C) dan suhu tinggi (40° ± 2°C). Hasil penelitian menunjukkan bahwa sediaan mikroemulsi memiliki stabilitas fisik yang lebih baik daripada sediaan emulsi.
Diclofenac sodium is a drug that can irritate the gastrointestinal tract and has first pass metabolisme, to overcome this problem, diclofenac sodium was made in transdermal dosage form. In the present study was formulated two kinds of transdermal dosage form in order to compare the differences in the total cumulative penetration of diclofenac sodium, i.e. emulsion and microemulsion using Virgin Coconut Oil as Oil Phase. Penetration ability through skin was examined by in-vitro Franz diffusion cell test using Sprague-Dawley rat abdomen skin. Total cumulative amount of diclofenac sodium penetrated from emulsion and microemusion were 911,00 ± 3,67 μg/cm2 and 445,41 ± 6,14 μg/cm2, respectively. Flux of diclofenac sodium from emulsion and microemulsion were 107,42 ± 1,25 μg/cm2.jam and 49,29 ± 0,63 μg/cm2.jam, respectively. The cumulative percentage of diclofenac sodium penetrated from emulsion and microemulsion were 15,68 ± 1,17 % and 8,80 ± 0,12 %, respectively. On the other hand, stability test including cycling test, centrifugation test and eight weeks storage at room temperature (28° ± 2°C), low temperature (4° ± 2°C) and high temperature (40° ± 2°C) was also done. The results showed that the microemulsion was more physically stable than emulsion."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2012
S43302
UI - Skripsi Open Universitas Indonesia Library
Suci Syafitri Utami
"Kurkumin merupakan salah satu bahan alam yang berfungsi sebagai antiinflamasi. Kurkumin memiliki bioavailabilitas yang rendah, dan tidak larut dalam air. Oleh karena itu, dapat diaplikasikan dalam bentuk nanoemulsi. Teknologi ini digunakan untuk meningkatkan kelarutan dan bioavailabilitas pada obat lipofilik. Tujuan penelitian ini ialah membuat dan membandingkan penetrasi dari sediaan nanoemulsi, nanoemulsi gel, dan emulsi gel kurkumin. Nanoemulsi dan nanoemulsi gel dibuat dengan 36% Tween 80 sebagai surfaktan, minyak kelapa sawit dan virgin coconut oil (VCO) sebagai fase minyak, dan etanol 96% sebagai kosurfaktan. Sedangkan emulsi gel dibuat dengan 15% Tween 80 sebagai surfaktan dan karbopol 940 2% sebagai gelling agent. Nanoemulsi, nanoemulsi gel, dan emulsi gel dibuat dan diukur ukuran globulnya menggunakan zetasizer. Ukuran partikel nanoemulsi, nanoemulsi gel dan emulsi gel berturut-turut ialah 10,07, 7,981, dan 4553 nm. Uji penetrasi in vitro kurkumin dilakukan menggunakan sel difusi Franz. Nanoemulsi gel memiliki jumlah kumulatif tertinggi yaitu 88,88± 22,58μg.cm-².
Curcumin is one of the natural compounds that used as an antiinflammation. Curcumin has a low bioavailability and insoluble in water. Because of that, curcumin can be applied in nanoemulsion form. This technologies being applied to enhance the solubility and bioavailability of lipophilic drugs.The aim of this study was to prepared and compared the in vitro penetration study of nanoemulsion, nanoemulsion gel, and emulsion gel curcumin. Nanoemulsion and nanoemulsion gel were prepared by 36% Tween 80 as surfactant, palm oil and virgin coconut oil (VCO) as oil phase, and 96% ethanol as cosurfactant. While emulsion gel were prepared by 15% tween 80 as surfactant and 2 % carbopol 940 as gelling agent. Their droplets size were measured using a zetasizer. Droplet size of nanoemulsion, nanoemulsion gel, and emulsion gel were 10.07, 7.981, and 4553 nm, respectively. In vitro penetration study was determined with Franz diffusion cell. Nanoemulsion gel showed the highest cumulative amount which was 88.88± 22.58μg.cm-²."
Depok: Fakultas Farmasi Universitas Indonesia, 2012
S43026
UI - Skripsi Open Universitas Indonesia Library
Hervee Novelda
"Red palm oil (RPO) mengandung antioksidan yang larut dalam lemak seperti karotenoid (α dan β-karoten, likopen), vitamin E (dalam bentuk α, β, dan δ tokotrienol dan tokoferol), dan ubikuinon. Red palm oil (RPO) dapat digunakan sebagai upaya mencegah stunting dan kekurangan gizi karena nilai gizi yang jauh lebih tinggi daripada minyak goreng yang beredar di pasaran. Akan tetapi, belum terdapat banyak studi mengenai pemanfaatan red palm oil (RPO) dalam hal tersebut. Penelitian ini bertujuan untuk memperoleh formula emulsi dari red palm oil (RPO). Sediaan emulsi red palm oil (RPO) dibuat menggunakan 5% sukrosa ester palmitat untuk mengemulsifikasi 5% (F1), 10% (F2), dan 15% (F3) red palm oil (RPO) dengan madu untuk menambah kestabilan, kemudian dilakukan karakterisasi fisik untuk mengetahui stabilitas emulsi selama 12 minggu. Hasil menunjukkan bahwa selama 12 minggu ketiga formula emulsi stabil berdasarkan parameter organoleptis, pH, homogenitas viskositas, ukuran partikel, dan zeta potensial. Hasil uji hedonis pada 30 orang responden menunjukkan bahwa formula F1 paling disukai para responden. Dengan demikian, dalam penelitian ini formula F1 menghasilkan hasil uji yang paling baik.
Red palm oil (RPO) contains fat-soluble antioxidants such as carotenoids (α and β-carotene, lycopene), Vitamin E (in the form of α, β, and δ tocotrienols and tocopherols), and ubiquinone. Red palm oil (RPO) can be used as an effort to prevent stunting and nutritional deficiencies due to its significantly higher nutritional value compared to cooking oils available in the market. However, there haven't been many studies regarding the utilization of red palm oil (RPO) in this matter. This study aims to obtain an emulsion formula from red palm oil (RPO). The red palm oil (RPO) emulsion preparations were made using 5% sucrose ester palmitate to emulsify 5% (F1), 10% (F2), and 15% (F3) red palm oil (RPO) with honey to enhance stability. Subsequently, a physical characterization was conducted to determine the emulsion's stability over a period of 12 weeks. The results showed that all three emulsion formulas remained stable over the 12-week period based on organoleptic parameters, pH, viscosity homogeneity, particle size, and zeta potential. Hedonic testing results from 30 respondents indicated that Formula F1 was the most preferred by the respondents. Therefore, in this study, Formula F1 yielded the best test results."
Depok: Fakultas Farmasi Universitas Indonesia, 2023
S-pdf
UI - Skripsi Membership Universitas Indonesia Library
Mahdi Jufri
2011
MK-Pdf
UI - Makalah dan Kertas Kerja Universitas Indonesia Library
Ohshima, Hiroyuki
Oxford: Elsevier, 2014
615.2 OHS c
Buku Teks SO Universitas Indonesia Library