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"ABSTRAKTujuan penelitian untuk mengetahui efektifitas SDF dalam menghambataktivitas karies gigi sulung serta melihat hubungan keadaan intraoral dengankeefektifitasan SDF dalam menghambat aktivitas karies gigi sulung pada anak. 115anak karies dentin aktif pada anak 2,5-6 tahun diaplikasikan SDF, selanjutnyadievaluasi setelah 3 dan 10 bulan dan keadaan intraoral diperiksa. Evaluasi setelah 10bulan menunjukkan 69,7% permukaan karies aktif menjadi terhenti. Uji statistikmenunjukkan karies aktif yang diaplikasikan SDF memiliki peluang 9.9 kali menjaditerhenti setelah 3 bulan, dan 6.4 kali setelah 10 bulan. Serta terdapat korelasi negatifbermakna secara statistik antara pulpitis dan skor pufa dengan keberhasilanintervensi SDF.

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ABSTRACTThe purpose of this study was to determine the effectiveness of SDF ininhibiting dental caries activity on primary teeth and find the relationship betweenintraoral situation with effectiveness of SDF in inhibiting childhood caries activity.115 children 2,5-6 years were applicated SDF on teeth that have active dentin caries,and then evaluated after 3 and 10 months. Intraoral state was examined. Evaluationafter 10 months showed 69.7% surface active caries to be arrested. The statistical testshowed that the active caries applied SDF have chance 9.9 times becoming arrestedafter 3 months, and 6.4 times after 10 months. There is a negative correlationstatistical significance of pulpitis and PUFA index with SDF intervention success."

"Karies merupakan masalah kesehatan gigi mulut yang paling tinggi pada anak usia 3-5 tahun di Indonesia. Mengobati karies sejak dini dapat menghilangkan rasa sakit dan meningkatkan kualitas hidup anak. SDF merupakan salah satu perawatan karies pada gigi sulung. 59 anak usia 3-5 tahun di Serpong diaplikasikan SDF pada permukaan gigi sulung yang karies dan di evaluasi setelah 3 bulan. Ibu subjek diberikan kuisioner pengukuran kualitas hidup sebelum dan sesudah aplikasi SDF. Setelah dioleskan SDF, 89,36% karies terhenti. Kualitas hidup 59 subjek meningkat setelah aplikasi SDF (p < 0,05). SDF efektif dalam menghentikan karies gigi sulung dan meningkatkan kualitas hidup anak.

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Caries is the highest oral health problem in children aged 3-5 yeard old in Indonesia. Early caries treatment can heal tootache and increase quality of life. SDF is one of caries treatment for primary teeth. 59 children aged 3-5 years old were applied SDF and evaluated 3 months later. Mothers are given quality of life questionairre before and after SDF application. After SDF application, 89,36% caries are arrested. Quality of life of the subjects are increased after SDF application (p<0,05). SDF is effective in treating primary teeth caries and increase children quality of life."

"Tujuan: Diketahuinya perbandingan efektiftas aplikasi silver diamine fluoride dengan propolis fluoride dalam menghambat karies gigi sulung. Metode: 224 anak usia 4-5 tahun dengan karies dentin aktif dialokasikan secara random pada satu diantara 3 kelompok perlakuan untuk pengobatan lesi karies dentin gigi sulung: Kelompok 1- Aplikasi Silver Diamine Fluoride, Kelompok 2- Aplikasi Propolis Fluoride, dan Kelompok 3- Kontrol. Evaluasi pemeriksaan dilakukan setelah 7 hari, 1 bulan dan 3 bulan untuk menilai banyaknya lesi karies yang menjadi terhenti. Hasil: Setelah 3 bulan, 163 (72,8%) anak menyelesaikan penelitian. Persentase karies yang menjadi terhenti adalah 88,68%, 55,78% dan 2,13% untuk Kelompok 1, Kelompok 2 dan Kelompok 3. Kesimpulan: Aplikasi Silver Diamine Fluoride atau Propolis Fluoride efektif menghambat lesi karies gigi sulung. Silver Diamine Fluoride lebih efektif dalam menghambat lesi karies dibanding Propolis Fluoride, tetapi Propolis Fluoride memiliki keunggulan tidak membuat perubahan warna gigi menjadi hitam.

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Objective: To compare the effectiveness of topical application of silver diamine fluoride (SDF) solution and topical application of propolis fluoride in arresting active dentine caries in primary teeth.

Methods: A total of 224 children, aged 3-4 years, were randomly allocated to one of three groups for treatment of carious dentine cavities in their primary teeth: group 1- application of SDF, group 2 ? application of Propolis Fluoride, group 3 ? control. Follow-up examinations were carried out 7 days, 1 month and 3 months to assess whether the treated caries lesions had become arrested.

Results: After 3 months follow up, 163 (72,8%) children remained in the study. The caries arrest rates were 88,68%, 55,78% dan 2,13% for group 1, group 2 and group 3.

Conclusion: Application of SDF solution or Propolis Fluoride solution can arrest active dentine caries. Topical application of SDF is more effective than Propolis Fluoride in inhibiting caries lesions progression, but Propolis Fluoride has the advantage that the arrested caries lesion will not turn black in colour like SDF."

"Studi ini bertujuan untuk mengetahui efek aplikasi SDF pada anak usia 36-71 bulan dalam menghentikan karies aktif dan menurunkan faktor risiko karies. Sampel yang digunakan adalah anak-anak PAUD Rama-rama yang dibagi menjadi dua kelompok secara acak: kelompok kontrol dan perlakuan. Skor karies dan pH plak anak diperiksa sebelum dan tiga bulan setelah dilakukan aplikasi SDF. Kuesioner ADA Caries Risk Assessment diisi oleh ibu subjek saat baseline. Terdapat perbedaan bermakna pada jumlah karies aktif dan pH plak anak kelompok perlakuan setelah dilakukan aplikasi SDF. Dapat disimpulkan bahwa SDF berpotensi efektif dalam menghentikan karies aktif gigi sulung dan menurunkan faktor risiko karies.

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The study aimed to assess the effect of SDF application to 36-71 months children in arresting active caries and decreasing caries risk factor. Samples were children at PAUD Rama-rama, randomly divided into two groups: control and intervention group. Caries score and plaque pH were examined before and three months after SDF application. ADA Caries Risk Assessment questionnaire was filled by subject’s mother. There were significant differences at number of active caries and plaque pH in intervention group after SDF application. It was concluded that SDF was potentially effective in arresting active caries on primary teeth and decreasing caries risk factor. rama randomly divided into two groups which are control and intervention group Teeth caries score and plaque pH were examined before and three months after SDF application ADA Caries Risk Assessment questionnaire was answered by subject rsquo s mother Result There were significant differences at number of active caries on decayed teeth p 0 000 mean SD 2 61 2 44 extracted teeth p 0 001 mean SD 1 10 2 80 and plaque pH p 0 008 mean SD 6 53 0 40 in control gorup compared to intervention group after SDF application Conclusion SDF was potentially effective in arresting active caries on primary teeth and decreasing caries risk factor."

"Karies merupakan penyakit infeksius yang paling sering terjadi pada anak di Indonesia. Oleh karena itu, dibutuhkan solusi yang dapat mengatasi karies, salah satunya dengan aplikasi Silver Diamine Fluoride (SDF). Tujuan: membahas evaluasi aplikasi SDF dalam mengatasi karies anak dan faktor-faktor yang berhubungan dengan persentase karies terhenti setelah aplikasi SDF. Metode: Studi kohort untuk evaluasi dan cross sectional dengan subjek penelitian 115 anak usia 3-5 tahun yang memiliki karies dentin aktif. Kuesioner diisi oleh orangtua untuk mengetahui faktor risiko karies. Hasil: Evaluasi pada 3 dan 10 bulan memperlihatkan permukaan karies aktif berpeluang terhenti 9.9 dan 6.8 kali setelah diaplikasi SDF, dibandingkan dengan yang tidak diaplikasi. Kesimpulan: SDF efektif menghentikan karies aktif anak serta meringankan rasa sakit yang diderita anak akibat karies sehingga berpotensi meningkatkan quality of life anak.

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Dental caries is one of the most prevalent infectious disease in children in Indonesia. Therefore, solution to overcome caries is needed.

Objective: evaluate Silver Diamine Fluoride (SDF) applications to overcome caries in children and factors related to the percentage of arrested caries after SDF application.

Method: Cohort study to evaluation and cross sectional with 115 children aged 3-5 years old who had active dentin caries were the subjects. Caries risk factors questionnaires filled by parents subject.

Results: Active caries which were applied SDF had odd ratios 9.9 and 6.8 times being arrested after 3 and 10 months, respectively, compared with those not applied.

Conclusion: SDF is effective to arrest caries and decrease toothache suffered by children, thus potentially increase the quality of life of children."

"Latar belakang: ECC adalah masalah kesehatan penting di Indonesia. Prevalensi dan keparahan usia dibawah tiga tahun meningkat, pencegahan harus dilakukan saat gigi erupsi. Gigi sulung berperan dalam proses tumbuh kembang anak, pemeliharaannya melibatkan peran ibu, antara lain pada pola pemberian ASI. Tujuan: Diketahuinya hubungan pola pemberian ASI dan berbagai faktor risiko kejadian ECC dan ditemukannya model pencegahan yang sesuai di DKI Jakarta. Metode: Cross-sectional pada 424 anak usia 6-24 bulan, wawancara, pemeriksaan klinis dan laboratorium.Hasil:Faktor prediktor ECC:plak, usia anak, cara pemberian, lama kontak ASI, dan kapasitas buffer saliva. Kesimpulan: Model menjelaskan 52,5% variasi ECC dengan akurasi prediksi 82%. Dihasilkan soft ware dan kartu sebagai alat bantu pencegahan ECC.

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Background: ECC is an important health problem in Indonesia. Under 3-yr-old prevalence and severity tend to increase, prevention must start since teeth eruption. Primary teeth plays role in the child development, oral care mainly involves the mother?s role, among others, breastfeeding pattern. Purpose: To determine relationship between breastfeeding patterns and ECC risk factors to find a prevention model in Jakarta. Methods: Cross-sectional study on 424 children aged 6-24 months, interviews, clinical and laboratory examinations. Result: ECC predictor factors: dental plaque, age, breastfeeding pattern, salivary buffer capacity. Summary:Model explained 52.5% variation in ECC with 82% accuracy prediction. Soft ware and card were developed as prevention model."

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Latar belakang: Early Childhood Caries (ECC) atau karies anak usia dini masih merupakan masalah kesehatan yang serius terutama di kalangan anak-anak. Streptococcus mutans diketahui sebagai penyebab utama dari ECC. Sementara bakteri lain seperti jamur, yaitu, Candida albicans, dianggap terlibat dalam proses perkembangan ECC. Resistensi atau kerentanan terhadap karies juga dipercaya dapat berkorelasi secara signifikan dengan perubahan komponen protein saliva. Beberapa mikroorganisme oral dan protein saliva tersebut dapat berfungsi sebagai biomarker untuk memprediksi risiko dan prognosis karies. Tujuan: Mengetahui kuantitas dari antigen Streptococcus mutans serotype c dan Candida albicans pada saliva pasien ECC serta menganalisis hubungan keduanya yang dikaitkan dengan OHI-S dan skor dmf-t. Metode: S. mutans serotype c dan Candida albicans yang diisolasi dari sampel saliva pasien ECC dan caries free diuji menggunakan Indirect ELISA untuk memperoleh kuantitas antigen S. mutans serotype c dan Candida albicans, yang selanjutnya dikorelasikan dengan OHI-S dan skor dmf-t pasien ECC dan caries free. Hasil: Kuantitas antigen S. mutans serotype c dan Candida albicans paling tinggi ditemukan pada pasien caries-free. Kuantitas antigen S. mutans serotype c paling tinggi ditemukan pada pasien dengan OHI-S sangat baik, sebaliknya pada Candida albicans kuantitas paling tinggi ditemukan pada pasien dengan OHI-S sedang. Secara statistik tidak terdapat perbedaan yang signifikan antara kuantitas antigen S. mutans serotype c dan Candida albicans pada pasien ECC dan caries-free. Secara statistik terdapat perbedaan yang signifikan antara kuantitas antigen Candida albicans pada kelompok OHI-S baik dan sedang, namun tidak pada antigen S. mutans serotype c. Pada pasien ECC dan caries free, antigen S. mutans serotype c dan Candida albicans memiliki arah dan bentuk korelasi yang positif. Kesimpulan: Peningkatan kuantitas antigen Streptococcus mutans serotype c dan Candida albicans tidak mencerminkan kondisi mulut pasien ECC maupun caries free. Peningkatan kuantitas antigen Streptococcus mutans serotype c dan Candida albicans dapat mencerminkan kondisi OHI-S pasien. Streptococcus mutans serotype c dan Candida albicans pada pasien ECC berkorelasi sementara pada pasien caries-free tidak.

 

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Background: Early Childhood Caries (ECC) or early childhood caries is still considered as serious health problem, especially among children. Streptococcus mutans is known as a major cause of ECC. While other bacteria such as fungi, that is, Candida albicans, are considered to be involved in the ECC progression. Resistance or susceptibility to caries is also believed to be significantly correlated with changes in salivary protein components. Some of these oral microorganisms and salivary proteins can be functioned as biomarkers to predict caries risk and prognosis. Objective: To determine the quantity of Streptococcus mutans serotype c and Candida albicans antigens in the saliva of ECC patients and analyze the relationship between the two antigens and associated with OHI-S and dmf-t scores. Methods: S. mutans serotype c and Candida albicans were isolated from saliva samples of ECC and caries free patients were tested using Indirect ELISA to obtain the quantity of S. mutans serotype c and Candida albicans antigen, which were correlated further with OHI-S and dmf-t scores of ECC and caries free patients. Results: The highest quantity of S. mutans serotype c and Candida albicans antigens was found in caries-free patients. The highest quantity of S. mutans serotype c antigen was found in patients with very good OHI-S, whereas the highest quantity of Candida albicans was found in patients with moderate OHI-S. There was no statistically significant difference between the quantity of S. mutans serotype c antigens and Candida albicans in ECC and caries-free patients. There is a significant difference statistically between the quantity of Candida albicans antigen in the good and moderate OHI-S group, but not in the S. mutans serotype antigen c. In patients with ECC and caries free, S. mutans serotype c antigens and Candida albicans have a positive direction and form of correlation. Conclusion: Increasing the quantity of Streptococcus mutans serotype c and Candida albicans antigens did not reflect the oral condition of ECC or caries free patients. The increase in the quantity of Streptococcus mutans serotype c and Candida albicans can reflect the patient's OHI-S condition. Streptococcus mutans serotype c and Candida albicans in ECC patients correlated but in caries-free patients they did not correlate.

 

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"Early Childhood Caries (ECC) adalah penyakit multifaktorial yang terdiri dari faktor etiologi, faktor demografi (usia, sosial ekonomi, tingkat pendidikan ibu) dan faktor perilaku (konsumsi makanan kariogenik, kebiasaan menyikat gigi, indeks plak, keluhan sakit gigi, dan kontrol ke dokter gigi). Penelitian ini mengguakan desain Cross Sectional dengan Uji Chi-Square. Hasil uji tersebut menunjukkan adanya perbedaan bermakna antara usia, sosial ekonomi, tingkat pendidikan ibu, konsumsi makanan kariogenik, indeks plak, keluhan sakit gigi, dan kontrol ke dokter gigi terhadap ECC dengan (p<0,05). Akan tetapi, dalam penelitian ini hanya kebiasaan menyikat gigi yang tidak berhubungan bermakna dengan ECC (p>0,05).

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Early Childhood Caries (ECC) is a multifactorial disease which factors are etiology factors, demographic factors (age, socioeconomic , mothers‟ level of education), and behavior factors (cariogenic diet, tooth brushing habit, plaque index, toothache complaints and dental visit). Cross sectional study with statiscal analysis using Chi- square showed that ages, socio-economic, mother‟s level of education, cariogenic diet, plaque index, dental visit, and toothache complaints have correlation with ECC (p<0,05). However, there are no correlation between tooth brushing habit with ECC (p>0,05)."

"Tujuan: Penelitian ini untuk mengetahui hubungan antara indeks plak terhadap efikasi Propolis Fluoride dalam menghambat aktivitas karies. Metode: 246 anak dengan karies aktif pada anak usia 36-71 bulan diaplikasikan Propolis Fluoride. 149 anak merupakan kelompok perlakuan dengan diberi perlakuan sikat gigi serta edukasi kesehatan gigi dan mulut rutin. Sedangkan 97 anak merupakan kelompok kontrol hanya diberi edukasi kesehatan gigi dan mulut pada saat baseline. Evaluasi pemeriksaan dilakukan setelah 3 bulan untuk menilai persentase karies yang menjadi arrested dan hubungannya dengan indeks plak. Hasil: Pada saat evaluasi 3 bulan persentase karies arrested pada kelompok perlakuan 62,44 sedangkan pada kelompok kontrol 46,18. Terdapat perbedaan bermakna rata-rata indeks plak dan jumlah karies aktif antara kelompok perlakuan dan kontrol. Terdapat hubungan yang signifikan bernilai negatif antara indeks plak dan persentase karies arrested. Terdapat hubungan yang signifikan bernilai positif antara skor tindakan dan persentase karies arrested. Kesimpulan: Terdapat hubungan yang signifikan antara indeks plak dan efikais Propolis Fluoride dalam menghambat aktivitas karies.

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Objective To determine the relationship between plaque index and efficacy of propolis fluoride in inhibiting caries activity. Method 246 children aged 36 71 month were applied Propolis Fluoride on every tooth surface that has active caries. 149 children are intervention group, they have been treated toothbrushing program and give them routine Dental Health Education. 97 children are control group only have been given Dental Health Education on the baseline. The evaluation and examination were conducted after 3 months to measure the percentage of arrested caries and the correlation with plaque index. Result At the 3 months evaluation, the percentage of arrested caries for both group of intervention and control were 62,44 and 46,18 respectively. There was a significant difference in mean plaque index and the number of active caries between two groups. There was a significant correlation between the plaque index and the percentage of arrested caries. There was a significant correlation between the behavior score and the percentage of arrested caries. Both correlation has negative and positive value respectively. Conclusion There is a significant correlation between plaque index and efficacy of Propolis fluoride in inhibiting caries activity."

"Karies gigi merupakan penyakit progresif yang terjadi akibat demineralisasi enamel gigi oleh aktivitas bakteri kariogenik yang menghasilkan asam, khususnya Streptococcus mutans. Dari berbagai penelitian, sediaan fluoride topikal terbukti memiliki efektivitas tinggi dalam menghentikan aktivitas karies gigi dengan biaya produksi yang rendah serta mudah untuk diaplikasikan. Tujuan penelitian ini adalah untuk memformulasikan sediaan alternatif fluoride topikal NH4F 5% dengan ekstrak etanol propolis (EEP) dalam suatu sistem mikroemulsi yang memiliki stabilitas, kemampuan antibakteri dan remineralisasi yang baik dalam menghentikan aktivitas karies gigi. Hasil penelitian menunjukkan bahwa formulasi 2,7% EEP; 6,3% surfaktan; dan 90,9% larutan NH4F 5% memiliki stabilitas penyimpanan terbaik. Uji antibakteri menunjukkan sediaan uji memiliki daya inhibisi pertumbuhan bakteri kariogenik sekitar 78-80%, dengan nilai konsentrasi hambat mínimum (KHM) pada pengenceran 6,25%. Hasil Scanning Electron Microscopy (SEM) dan Energy Dispersive X-Ray (EDX) menunjukkan sediaan berhasil meremineralisasi permukaan enamel gigi dengan deposit fluoride hingga 5 - 6 x dibandingkan kontrol. Kesimpulan dari penelitian ini adalah sediaan mikroemulsi propolis fluoride (PF) dapat menjadi alternatif sediaan fluoride topikal yang memiliki efektivitas tinggi dalam menghentikan aktivitas karies gigi.

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Dental caries is a disease caused by demineralization of tooth enamel by the activity of cariogenic bacteria that produce acid, especially Streptococcus mutans. From various studies, preparation of topical fluoride is proven to have higher efficacy in preventing dental caries with low production cost and easy to apply. The objective of this research is to formulate alternatife agent topical fluoride NH4F 5% mixed with extract ethanol propolis (EEP) in the microemulsion system that has high stability, antimicrobial activity, and remineralisation to arrest teeth caries activity.

The result shows that formulation 2,7% EEP; 6,3% surfactan; and 90,9% NH4F solution has the highest perervation stability. Antibacterial test shows three simple have ability to inhibit cariogenic bacteria development around 78-80% with mínimum inhibtory concentration (KHM) value at 6,25% dilution. Scanning Electron Microscopy (SEM) and Energy Dispersive X-Ray (EDX) result show that sample succesfuly reminerilize enamel surface with fluoride deposite up to 5 - 6 x compared by control. The conculsion from this research is microemulsion agent propolis fluoride (PF) can become topical fluoride alternatife that has high effectivity."