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"Because of its high predictability of success, implant therapy is a reliable treatment for replacement of missing teeth. The concept of immediate implant loading has been widely accepted in terms of early esthetic and functional recovery. However, there is little biological evidence to support this concept. The objective of this study was to examine the interactive effects of mechanical loading and surface roughness of immediately loaded titanium implants on bone formation in rats. Screw-shaped anodized titanium implants were either untreated (smooth) or acid-etched. Two implants were inserted parallel to each other in the tibiae of rats, and a closed coil spring (2.0 N) was immediately applied. Trabecular and cortical bone around both implants was analyzed using microtomographic images, and a removal torque test was performed at weeks 1, 2, and 4. Immediate loading of acid-etched implants resulted in significant decreases in bone mineral density, contact surface area, and cortical bone thickness. These effects were not observed after immediate loading of smooth implants. Conversely, loading did not influence acid-etched implant fixation; however, smooth implant fixation at week 1 was significantly reduced. These results imply that surface roughness regulates bone response to mechanical stress and that immediate loading might not inhibit osseointegration for smooth and rough implants in the late healing stages."

"Angiogenesis plays a key role in bone formation and maintenance. Bone formation has been reported to initiate in the concavities rather than the convexities in a hydroxyapatite substratum and the implant threads of dental implants. The aim of the present study was to evaluate the number of the blood vessels inside the concavities and around the convexities of the threads of implants in a rabbit tibia model. A total of 32 thread-shaped implants blasted with apatitic calcium phosphate (TCP/HA blend) (Resorbable Blast Texturing, RBT) (Maestro, BioHorizons®, Birmingham, AL, USA) were inserted in 8 rabbits. Each rabbit received 4 implants, 2 in the right and 2 in left tibia. Implants were retrieved after 1, 2, 4, and 8 weeks and treated to obtain thin ground sections. Statistically significant differences were found in the number of vessels that had formed in in the concavities rather than the convexities of the implants after 1 (p = 0.000), and 2 weeks (p = 0.000), whilst no significant differences after 4 (p = 0.546) and 8 weeks (p = 0.275) were detected. The present results supported the hypothesis that blood vessel formation was stimulated by the presence of the concavities, which may provide a suitable environment in which mechanical forces, concentrations and gradients of chemotactic molecules and blood clot retention may all drive vascular and bone cell migration."

"Penambahan dopan logam Cu dilakukan dalam modifikasi permukaan permukaan Ti6Al4V, untuk merancang fotokatalitik sistem dengan efisiensi tinggi di bawah cahaya tampak. Mendopankan logam Cu pada permukaan fotokatalis menggunakan metode photo-assisted deposition. Variasi konsentrasi logam Cu (0,05 M; 0,10 M; 0,15 M) dilakukan untuk memperoleh kondisi optimum fotokatalis yang aktif dibawah cahaya tampak. Hasil karakterisasi SEM-EDX dan XRD, menunjukkan bahwa sampel yang dianodisasi dengan elektrolit gliserol memiliki morfologi dan kristalinitas lebih baik dibandingkan sampel yang dianodisasi dengan elektrolit asam. Hasil uji pembentukan biofilm secara in vitro dengan bakteri Streptococcus mutans menunjukkan sampel yang didopankan dengan dopan Cu berkonsentrasi 0,15 M memiliki kinerja fotokatalitik yang paling baik, dengan hasil sebesar 99% persentase disinfeksi bakteri dibandingkan dengan model kontrol pada jam ke-16 pengukuran. Hasil ini menunjukkan sampel yang didopankan dengan dopan Cu berkonsentrasi 0,15 M merupakan kondisi optimum untuk menghambat pembentukan biofilm dalam penelitian ini

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Optimization of morphology and crystallinity of TiO2 nanotubes (TNT) fabricated on the surface of Ti6Al4V with anodizing method using a variation of the type of electrolyte. To design a system with high efficiency photocatalytic under visible light, the addition of a transition metal dopant antibacterial namely Cu (Copper). Cu-doped surface on the dental implat using photo-assisted deposition method. Variations in the concentration of Cu (0.05 M; 0.10 M; 0.15 M) were performed to obtain the optimum conditions photocatalysts active under visible light. Results of SEM-EDX and XRD characterization, indicate that the sample which is anodized with glycerol electrolyte, have better morphology and crystallinity than the sample which is anodized with acid electrolyte. The test results of in vitro biofilm formation test by Streptococcus mutans showed sample of which doped with Cu that have concentration of 0,15 M has the best photocatalytic performance, with percentage of disinfection of bacteria at 99% compared with the control model at 16th hour measurement. These results show the samples TNT/G/0,15 which doped with Cu dopant concentration of 0,15 M is an optimum condition to inhibit biofilm formation in the study"

"Implan gigi merupakan perawatan medis bagi gigi tanggal yang diakibatkan oleh berbagai kelainan periodontitis, maupun karies, trauma, serta kelainan pada perkembangan dan genetik, dengan tingkat keberhasilan mencapai 95% ditandai oleh kemampuan implan gigi melakukan osseointegrasi. Osseointegrasi dipengaruhi oleh beberapa hal, termasuk kualitas dan kuantitas tulang, serta desain implan gigi. Kegagalan implan gigi dapat terjadi pada tulang dengan kualitas lebih rendah akibat kelelahan yang berlebihan, serta desain implan gigi yang tidak memadai. Pada beberapa penelitian yang telah dilakukan, menunjukkan bahwa fitur self-tapping memiliki tingkat keberhasilan yang sama dengan implan gigi tanpa fitur ­­self-tapping, namun dengan torsi insersi yang lebih sederhana, sehingga dapat mengurangi risiko kerusakan tulang dan meningkatkan stabilitas primer dengan meminimalisir jumlah drilling yang digunakan. Penelitian ini dilakukan dengan melakukan simulasi finite element pada variasi desain cutting flute, berupa sudut kemiringan celah pemotong, panjang celah pemotong, dan jumlahnya, untuk menjalankan fungsi self-tapping. Simulasi ini dijalankan dengan memberikan pembebanan oklusal pada implan gigi yang dipasang pada tulang berdensitas rendah (tulang tipe III). Dari simulasi tersebut, dilakukan analisis distribusi tegangan dan strain yang terjadi pada implan gigi. Desain implan gigi dengan tiga buah celah pemotong dengan sudut kemiringan 5? di sepanjang badan implan yang berulir memiliki nilai tegangan Von Mises maksimum paling rendah, sebesar 92,127 MPa, bersesuaian dengan nilai strain maksimum paling rendah, yaitu 0,000555.

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Dental implant is a medical treatment for missing tooth caused by various conditions such as periodontitis, cavities, trauma, as well as abnormalities in growth and genetics, with a success rate of up to 95%, characterized by the ability of dental implants to achieve osseointegration. Osseointegration is affected by several factors, including the quality and quantity of bone, as well as the design of dental implants geometry. Dental implants failure can occur in lower quality bone due to excessive fatigue and inadequate implant design for acquired conditions. Research indicates that self-tapping features have the same success rate as dental implants without self-tapping features, but offer simpler insertion torque, reducing the risk of bone damage and improving primary stability by minimizing the drilling procedures. This study was conducted by performing finite element simulations on various cutting flute design, including the angle of the cutting flute, length of the cutting flute, and the number of cutting flute, to provide a self-tapping function. The simulation was conducted by applying occlusal loading to dental implants placed in low-density bone (bone type III). From the simulation, an analysis of stress distribution and strain in dental implants. Among the developed dental implant designs, the one featuring three cutting flutes at a 5? angle along the threaded implant body exhibits the lowest maximum Von Mises stress value of 92,127 MPa, as well as the lowest maximum strain value of 0,000555."

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Latar Belakang: Implan gigi sebagai alternatif perawatan kehilangan gigi dapat mengalami kegagalan akibat distribusi stress yang berlebihan. Desain implan berupa implant thread depth menjadi bagian penting dari struktur implan yang dapat mempengaruhi distribusi stress. Adapun arah pembebanan dan tulang dengan densitas rendah merupakan faktor lain yang dapat mempengaruhi distribusi stress. Tujuan: Untuk mengetahui gambaran distribusi stress pada single implant dengan variasi ukuran thread depth dan arah pembebanan di tulang densitas rendah. Metode: Penelitian ini adalah penelitian observasional deskriptif. Model 3D regio posterior tulang maksila  dan tiga implan dengan komponen implan berupa panjang 10 mm, diameter 4,1 mm, thread pitch 0,8 mm, thread shape berupa V-thread dan kedalaman thread depth yang terbagi menjadi 0,25 mm; 0,35mm; dan 0,45mm dibuat dengan modeling software dan disusun menjadi solid model. Dilakukan simulasi pemberian beban preload 200 N arah axial pada screw dan dilanjutkan dengan pemberian beban mastikasi sebesar 100 N arah axial dan oblique pada molar pertama. Dilakukan analisis dengan metode finite element untuk mengetahui distribusi stress berupa von Mises stress pada komponen implan dan tulang. Hasil : Nilai von Mises stress maksimum tertinggi pada pembebanan axial (abutment = 222,63 MPa, implant body = 179,68 MPa, dan screw = 154,97 MPa), pada pembebanan oblique (abutment = 1086,9 MPa, implant body = 852,46 MPa, dan screw = 628,56 MPa). Pada tulang alveolar, nilai von Mises stress maksimum dengan pembebanan axial pada masing-masing thread depth (0,25 mm = 29,421 MPa; 0,35 mm = 30,201 MPa; 0,45 mm = 31,091 MPa), dan dengan pembebanan oblique pada masing-masing thread depth (0,25 mm = 74,103 MPa; 0,35 mm = 75,102 MPa; 0,45 mm = 76,557 MPa). Kesimpulan : Hasil metode finite element menunjukkan bahwa pada pembebanan axial, abutment mengalami peningkatan stress seiring peningkatan thread depth. Pada pembebanan oblique seluruh komponen implan mengalami peningkatan stress seiring peningkatan thread depth. Nilai von Mises stress terbesar pada tulang ditemukan pada thread depth 0,45 mm dengan pembebanan oblique.

 

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Background: Dental implants as an alternative treatment for tooth loss can fail due to excessive stress distribution. Implant design in the form of implant thread depth is an important part of the implant structure that can affect stress distribution. The direction of loading and low-density bone are other factors that can affect stress distribution. Objective: To determine the overview of stress distribution of a single implant with varying thread depth in low-density bone. Methods: This study was a descriptive observational study. A 3D model of the posterior region of the maxillary bone and three implants with implant components of 10 mm length, 4 mm diameter, 0.8 mm thread pitch, V-thread thread shape, and thread depth divided into 0.25 mm; 0.35mm; and 0.45mm were created with modeling software and compiled into a solid model.  Simulation of 200 N axial preload was applied to the screw and followed by 100 N axial and oblique mastication load on the first molar. Finite element method analysis was performed to determine the stress distribution in the form of von Mises stress on the implant and bone components. Results: The highest maximum von Mises stress values under axial loading (abutment = 222.63 MPa, implant body = 179.68 MPa, and screw = 154.97 MPa), under oblique loading (abutment = 1086.9 MPa, implant body = 852.46 MPa, and screw = 628.56 MPa). In alveolar bone, the maximum von Mises stress value with axial loading at each thread depth (0.25 mm = 29.421 MPa; 0.35 mm = 30.201 MPa; 0.45 mm = 31.091 MPa), and with oblique loading at each thread depth (0.25 mm = 74.103 MPa; 0.35 mm = 75.102 MPa; 0.45 mm = 76.557 MPa). Conclusion: The results of the finite element analysis showed that in axial loading, the abutment experienced increased stress as thread depth increased. In oblique loading, all implant components experienced increased stress as thread depth increased. The largest von Mises stress value in the bone was found at a thread depth of 0.45 mm with oblique loading.

 

 

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"Latar belakang : Kasus kehilangan gigi seringkali menjadi masalah bagi kebanyakan orang. Salah satu perawatan yang dapat dilakukan pada kasus kehilangan gigi adalah dengan penggunaan implan gigi. Tingkat keberhasilan implan salah satunya yaitu dilihat dari osseointegrasi. Berbagai macam modifikasi permukaan implan yang ada merupakan strategi yang telah dilakukan dan dikembangkan untuk mempercepat osseointegrasi. Dengan demikian, peneliti tertarik untuk mengetahui hubungan permukaan implan terhadap proses osseointegrasi. Tujuan: Mengetahui permukaan implan yang paling umum ditemukan pada pasien 40 – 65 tahun, serta hubungan permukaan implan terhadap osseointegrasi. Metode: Penelitian ini menggunakan desain penelitian deskriptif analitik untuk menganalisis korelasi dengan metode pendekatan retrospektif dimana sampel berasal dari data IPKGII sebanyak 3629 pasien pemasangan implan. Sesuai tujuan penelitian, permukaan yang diambil adalah permukaan yang paling umum ditemukan yaitu SLA (merk: Alpha Bio, Dentium, Dentium Superline, TRI, TRI TV), SA (merk: Osstem, Osstem GS, Osstem TS, dll), SLActive (merk: Straumann RN, Straumann WN, dll). Berdasarkan data yang tersedia, osseointegrasi diukur dari rentang waktu tanggal pemasangan implan hingga pemasangan protesa pada pasien. Hasil: Dalam penelitian ini, terdapat hubungan yang bermakna signifikan antara kelompok permukaan implan yang paling banyak ditemukan pada pasien usia 40 – 65 tahun, yaitu permukaan SLA, SA, dan SLA Active (p < 0,05). Kesimpulan: Hasil penelitian sejalan dengan teori bahwa permukaan implan, dalam penelitian ini seperti jenis permukaan SLA, SA, dan SLActive memiliki hubungan dengan proses osseointegrasi melalui stabilitas implan.

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Background : Tooth loss often becomes an issue for most people. One of the treatments that can be done in case of tooth loss is the use of dental implants Implant success rate is measured by osseointegration. Various designs and modifications of existing implant surfaces are evidence of strategies that have been undertaken and developed to accelerate osseointegration. Thus, researcher is interested in discovering the effect of implant surface modification on the osseointegration process. Objective: Discovering the most common implant surfaces found in patients 40 – 65 years old, as well as the correlation between implant surface and osseointegration process. Metode: This study used a descriptive analytical research design to analyze correlation using a retrospective approach method in which sample was from IPKGII data of 3629 implants in patients According to the research objectives, the surfaces taken are the most commonly found surfaces, namely SLA (brands: Alpha Bio, Dentium, Dentium Superline, TRI, TRI TV), SA (brands: Osstem, Osstem GS, Osstem TS, etc.), SLActive (brands: Straumann RN, Straumann WN, etc.). Based on available data, osseointegration was measured from the date of implant placement to the patient's prosthesis installation. Result: In this study, there was a significant correlation between the most common group of implant surfaces used in patients aged 40 – 65 years the length of time until osseointegration occurs (p < 0.05). Conclusion: The research results are parallel with the theory that the implant surface, such as SLA, SA, and SLAactive in this research, has a correlation with the osseointegration process through implant stability."

"Kehilangan gigi telah menjadi salah satu permasalahan yang umum untuk ditemukan di Indonesia, dengan angka sekitar 19% kasus gigi hilang akibat dicabut ataupun tanggal sendiri. Untuk mengatasi permasalahan kehilangan gigi, implan gigi merupakan alternatif yang banyak digunakan karena sudah terbukti dapat memberikan hasil yang baik secara jangka panjang. Keberhasilan pemasangan implan gigi dinilai berdasarkan tingkat stabilitasnya, yang terbagi kembali menjadi stabilitas primer dan stabilitas sekunder. Kedua jenis stabilitas tersebut saling berkaitan. Kekhawatiran akan pemasangan implan gigi banyak ditemukan pada kasus dimana pemasangan dilakukan pada pasien dengan tulang berkepadatan rendah. Tulang tempat terpasangnya implan gigi yang memiliki kualitas dan kepadatan yang kurang baik memiliki risiko kegagalan implan yang lebih tinggi. Untuk dapat meningkatkan tingkat stabilitas implan, banyak dilakukan proses modifikasi desain dan permukaan implan gigi, seperti penambahan fitur self-tapping dan peningkatan kekasaran permukaan badan implan. Fabrikasi dilakukan untuk menghasilkan purwarupa implan gigi dengan variasi sudut kemiringan dan panjang cutting flute, sebagai bagian dari fitur self-tapping. Purwarupa akan melalui proses surface treatment untuk mendapatkan tingkat kekasaran yang optimum untuk penggunaannya pada tulang berkepadatan rendah. Purwarupa akan diuji dengan uji torsi insersi dan uji pull-out test. Purwarupa 1 menunjukkan performa terbaik dengan nilai kekasaran permukaan sebesar 1,0636 μm, serta nilai insertion torque value dan pull-out load sebesar 22,4415 Ncm dan 317,068 N.

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Tooth loss has become a common health issue in Indonesia, with approximately 19% of cases resulting from extraction or natural loss. Dental implant are widely used as an alternative due to their proven long-term effectiveness. The success of dental implant placement is evaluated based on its stability, which can be categorized as primary stability and secondary stability. Both types of stability are interrelated with one another. Concerns about dental implant placement are often encountered when dealing with patients with low bone density. Poor quality and low-density bone in the implant insertion site might result in a higher risk of implant failure. To improve implant stability, various modifications are made to the design and surface of the implant body, such as adding self-tapping features and increasing the surface roughness of the implant body. Fabrication is done to produce dental implant prototypes with variations in in angulation and length of the cutting flute, as a part of the self-tapping feature. These prototypes will undergo surface treatment to achieve an optimal level of surface roughness for use in low bone density. Each prototypes are then tested using insertion torque test and pull-out tests. Prototype 1 showed the best performance with a surface roughness value of 1,0636 μm, as well as an insertion torque value of 22,4415 Ncm and a pull-out load of 317,068 N."

"Osteoporosis has become a worldwide problem and has been known as a silence disease. Nowadays, there are a lot of diagnostic tools for detecting osteoporosis. Eighty eight postmenopausal were included and underwent digital panoramic, digital periapical, and conventional radiography. Ultrasound bone densitometry of os calcis used as goldstandard. Correlation between stiffness index (SI) with a digital dental, digital panoramic and conventional dental radiography are 0.170 (p = 0.11), -0382 (p = 0.001) and 0.246 (p = 0.021) respectively. Significant relationship was found between the SI only with digital panoramic and conventional dental. The highest correlation was found between SI values with mandibular Inferior Cortex on digital panoramic (-0.382, Pearson Correlation Tests). Correlationbetween digital panoramic radiographs and the SI values was the highest of the three radiographic modalities in this study. This indicates that evaluation of cortical bone is more accurate than cancellous bone. Bone quality evaluation in patients at high risk for osteoporosis using panoramic and dental conventional radiograph by dentist, contributes in preventing further occurrence of osteoporosis which in turn could reduce mortality and morbidity of osteoporosis inIndonesia."

"Kehilangan gigi merupakan masalah yang umum terjadi di masyarakat. Untuk itu diperlukan implant gigi dengan desain dan material yang dapat meningkatkan osseointegrasi dan juga kekuatan mekanik yang baik. Salah satu metode untuk membuat implant gigi ini yaitu dengan metode metal injection molding. Wrought material Ti6Al4V dengan dimensi 5 mm x 5 mm x 3 mm yang sudah dilakukan surface treatment dengan pengamplasan grit P80, P180, dan P600 dimasukkan ke dalam cetakan berbentuk kubus dengan dimensi 5 mm x 5 mm x 5 mm kemudian diinjeksikan Feedstock Ti6Al4V hingga cetakan terisi penuh dan menempel pada wrought material Ti6Al4V. selanjutnya dilakukan proses solvent debinding dengan larutan heksana selama 3 jam pada temperature 60 °C dan dilanjutkan thermal debinding dengan temperature 600 °C dengan heating rate 5 °C/menit dengan waktu tahan 60 menit menggunakan atmosfer argon. Proses sintering menggunakan temperature 1150 °C dengan waktu tahan 60 menit, 90 menit, dan 120 menit pada atmosfer argon dengan flow rate 1 liter/menit. Hasil penelitian menunjukkan bahwa waktu tahan sintering berpengaruh pada persentase porositas dan juga kekerasan material Ti6Al4V. Pada kekerasan material porous Ti6Al4V terdapat peningkatan kekerasan sedangkan pada wrought material Ti6Al4V terjadi penurunan kekerasan pada waktu tahan sintering 120 menit karena fenomena pertumbuhan butir. Kekasaran permukaan sangat berpengaruh pada shear bond strength pada permukaan dengan nilai kekasaran permukaan yang tinggi maka shear bond strength juga akan semakin tinggi. Pada penelitian ini hasil shear stress yang tertinggi sebesar 1,5406 Mpa pada kekasaran permukaan Ra sebesar 2,3677 μm

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Tooth loss is a common problem in society. For this reason, dental implants with designs and materials that can improve osseointegration and good mechanical strength are needed. One of the methods for making dental implants is the metal injection molding method. Wrought material Ti6Al4V with dimensions of 5 mm x 5 mm x 3 mm which has been surface treated with grinding paper P80, P180, and P600 is inserted into a cube-shaped mold with dimensions of 5 mm x 5 mm x 5 mm then injected with Feedstock Ti6Al4V until the mold is filled full and attached to the wrought Ti6Al4V material. The solvent debinding process with hexane was carried out for 3 hours at a temperature of 60 °C and continued by thermal debinding at a temperature of 600 °C with a heating rate of 5 °C/minute with a holding time of 60 minutes using an argon atmosphere. The sintering process uses a temperature of 1150 °C with holding times of 60 minutes, 90 minutes, and 120 minutes in an argon atmosphere with a flow rate of 1 liter/minute. The results showed that the sintering resistance time affects the percentage of porosity and also the hardness of the Ti6Al4V material. In the hardness of the porous Ti6Al4V material there is an increase in hardness, while in the wrought material Ti6Al4V there is a decrease in the hardness at a sintering time of 120 minutes due to the grain growth phenomenon. Surface roughness is very influential on the shear bond strength on a surface with a high surface roughness value, the shear bond strength will also be higher. In this study, the highest shear stress was 1.5406 Mpa at a surface roughness Ra of 2.3677 μm"