Ditemukan 18646 dokumen yang sesuai dengan query
"This reference discusses the predictive power and limitations of current stress testing strategies and emphasizes the critical role of stress testing in the determination of the stability characteristics of pharmaceuticals-offering an extensive compilation of drug degradation studies from real-world examples in the literature. Richly illustrated and extensively referenced, this source details the execution and interpretation of small molecule stress testing studies, provides a comprehensive overview of the major aspects of the prediction of drug degradation, presents up-to-date approaches to pharmaceutical stress testing, and much more"
London: Informa Healthcare, 2011
615.19 PHA
Buku Teks SO Universitas Indonesia Library
Baertschi, Steven W.
"Summary:
"This reference discusses the predictive power and limitations of current stress testing strategies and emphasizes the critical role of stress testing in the determination of the stability characteristics of pharmaceuticals-offering an extensive compilation of drug degradation studies from real-world examples in the literature. Richly illustrated and extensively referenced, this source details the execution and interpretation of small molecule stress testing studies, provides a comprehensive overview of the major aspects of the prediction of drug degradation, presents up-to-date approaches to pharmaceutical stress testing, and much more"--Provided by publisher"
London: Informa Healthcare, cop, 2011
615.19 BAE p
Buku Teks SO Universitas Indonesia Library
Watson, David G.
Edinburgh: Churchill Livingstone Elsevier, 2012
615.190 WAT p
Buku Teks SO Universitas Indonesia Library
"This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation.
"
Weinheim, Germany: Wiley-VCH, 2008
e20395825
eBooks Universitas Indonesia Library
Lee, Mike S.
"Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the context of drug development, including the discovery, preclinical, clinical, and manufacturing phases. In addition to the thorough technical analysis of this tool, LC/MS Applications in Drug Development provides perspective on the significant changes in strategies for pharmaceutical analysis. A process overview of drug development from an analytical point of view is provided along with essential data required to successfully bring a drug to market. The incorporation of LC/MS is illustrated from target to product. Chapters pertaining to the discovery process itself include : proteomics, glycoprotein mapping, natural products dereplication, lead identification screening, open-access LC/MS, in vitro drug screening written for both the analytical chemist who uses LC/MS applications and the pharmaceutical scientist who works with the drugs they produce."
New York: John Wiley & Sons, 2002
e20394207
eBooks Universitas Indonesia Library
"Drug-drug interactions in pharmaceutical development comprehensively reviews the relevant science, industrial practice, and regulatory agency positions on drug-drug interactions. It focuses on the evaluation of potential drug-drug interactions, allowing researchers to address risk factors before a drug is put to market. The book covers both clinical and nonclinical aspects for understanding drug-drug interactions as well as in vitro and in vivo studies for use in studying interactions at the drug discovery stage."
Hoboken, New Jersey: John Wiley & Sons, 2008
e20395865
eBooks Universitas Indonesia Library
Amsterdam: Elsevier/Academic Press, 2011
R 615.19 HAN
Buku Referensi Universitas Indonesia Library
New York: Marcel Dekker, 2000
615.18 DRU
Buku Teks SO Universitas Indonesia Library
Ansel, Howard C., 1933-
Philadelphia: Wolters Kluwer, 2017
615.14 ANS p
Buku Teks SO Universitas Indonesia Library
"Summary:
A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. This book considers these key research and industrial tools."
Oxford: Woodhead Publishing, 2013
615.19 FOR
Buku Teks SO Universitas Indonesia Library