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"This book provides a state-of-the-art approach to the molecular basis of hematologic diseases and its translation into improved diagnostics and novel therapeutic strategies. Several representative hemato-oncologic malignancies are analyzed in detail: acute lymphoblastic leukemia, acute myeloid leukemia, B-cell Non-Hodgkin lymphomas, multiple myeloma, chronic lymphocytic leukemia, chronic myeloid leukemia, myelodysplastic syndromes, and myeloproliferative neoplasms. Experts in the field describe the molecular methods applied for modern diagnostics and therapies, such as hematopoietic stem cell transplantation, donor recipient matching, banking of biological material, analyses of post-transplant chimerism, and minimal residual disease monitoring. The volume concludes with an extensive section comprising thorough step-by-step protocols of molecular techniques in hematology, all of them validated in the authors? own laboratories."

"Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes w."

"[This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field., This book offers an overview of state-of-the-art in non amplified DNA detection methods and provides chemists, biochemists, biotechnologists and material scientists with an introduction to these methods. In fact all these fields have dedicated resources to the problem of nucleic acid detection, each contributing with their own specific methods and concepts. This book will explain the basic principles of the different non amplified DNA detection methods available, highlighting their respective advantages and limitations. Non-amplified DNA detection can be achieved by adopting different techniques. Such techniques have allowed the commercialization of innovative platforms for DNA detection that are expected to break into the DNA diagnostics market. The enhanced sensitivity required for the detection of non amplified genomic DNA has prompted new strategies that can achieve ultrasensitivity by combining specific materials with specific detection tools. Advanced materials play multiple roles in ultrasensitive detection. Optical and electrochemical detection tools are among the most widely investigated to analyze non amplified nucleic acids. Biosensors based on piezoelectric crystal have been also used to detect unamplified genomic DNA. The main scientific topics related to DNA diagnostics are discussed by an outstanding set of authors with proven experience in this field.]"

"This completely updated second edition of Radiation exposure and image quality in x-ray diagnostic radiology provides the reader with detailed guidance on the optimization of radiological imaging. The basic physical principles of diagnostic radiology are first presented in detail, and their application to clinical problems is then carefully explored. The final section is a supplement containing tables of data and graphical depictions of X-ray spectra, interaction coefficients, characteristics of X-ray beams, and other aspects relevant to patient dose calculations. In addition, a complementary CD-ROM contains a user-friendly Excel file database covering these aspects that can be used in the reader’s own programs. "

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ABSTRACTOral bacteria are the first human microbiome to encounter the food we eat. To date, most research has focused on the role of oral bacteria in the development and progression of caries and periodontal disease; however, little is known about the microbial communities that maintain a healthy oral cavity. This book, Oral Microbial Communities: Genomic Inquiry and Interspecies Communication, helps readers understand how multispecies microbial communities function to maintain and promote oral health as well as disease. It explores the immense opportunities presented by readily accessible, genetically tractable, genome-sequenced oral species that naturally form multispecies communities. Emphasizing the use of genomic inquiry to probe questions, Oral Microbial Communities examines multispecies community interactions, spatiotemporal organization, and gene function. Readers will find coverage of all the major microbe species currently under investigation by leading oral microbiologists. In particular, the book highlights model systems that study oral bacterial interactions, including biofilm growth using saliva as the source of nutrition."

"Post genomics drug discovery and research explores and discusses some of the most important topics in post-genomics life and biopharmaceutical sciences. It provides an introduction to the field, outlining examples of many techniques currently used, as well as those still under development, which are important for the research of biopharmaceutical discovery in the post-genomics era.Integrates several developing and cutting-edge technologies and methods like bioinformatics, experimental therapeutics, and molecular recognitionIncludes discussion on topics such as : computer-aided ligand design, peptide and protein chemistry and synthesis, synthesis of active natural products, and the use of emerging technologies like proteomics, nanotechnology, or bioengineering."

"A rapid and simple to amplify genomic DNA sequences nanking mini-Tn5 transposon insertion was developed....."