Hasil Pencarian  ::  Simpan CSV :: Kembali

"L'ouvrage présente les données générales sur la pharmacologie de l’activité anti–infectieuse (et surtout l’activité anti-bactérienne) puis sur les principales pathologies infectieuses susceptbles d’être traitées par les des médications phytothérapiques (plantes sous forme de gélules, spécialités phytothérapiques à bases d’extrait(s) de plantes, huiles essentielles issues de plantes aromatiques). Enfin il traite des principales plantes utilisées en thérapeutique anti-infectieuse."

"This book, with the focus on the most advanced cutting-edge breakthroughs, covers all the essential aspects of the field of molecular farming in plants: from expression technologies to downstream processing, from products to safety issues, and from current advances and holdups to future developments. "

"Contents: The European legislation (directive 2004/24/EC) brings clarification and recognition to herbal medicinal products / Giuseppe NisticoÌ? and Dagmar Roth-Behrendt -- Taxonomy, morphology, and ecology of medicinal plants: a botanical perspective / Simon Pierce, Alessandra Luzzaro, and Bruno E.L. Cerabolini -- Ethnopharmacological approaches used to identify medicinal plants / Tsukasa Sakurada ... [et al.] -- Medicinal plants : molecular biology/biotechnology approach -- Candida Vannini ... [et al.] -- Breeding and cultivation of medicinal plants / Christoph Carlen -- Sample preparation, analytical methods, and chemical standardization of medicinal plants -- Angela Perrone ... [et al.] -- The role of zebrafish in the future of natural product discovery -- Alexander D. Crawford, Camila V. Esguerra, and Peter A.M. de Witte -- Phytocomplexes versus single-entity drugs : the never-ending dilemma in herbal medicine / Elizabeth M. Williamson -- Molecular modes of action of drugs used in phytomedicine / Michael Wink -- Bioavailability issues of nonnutrient plant and fruit constituents / Mariusz Konrad Piskula and Junji Terao -- From identification to clinical translation of medicinal plants / Gian Franco Gensini ... [et al.] -- Recommendations for reporting randomized controlled trials of herbal medicine interventions / Joel J. Gagnier ... [et al.] --Pharmacovigilance methods and systems in herbal medicines / Gioacchino Calapai -- Mechanisms and clinical relevance of herb drug interactions from the perspectives of pharmacokinetics / Laura Berliocchi ... [et al.] -- Nature?s gift to photodynamic medicine : hypericin, a herbal photosensitizer is a component of hypericum perforatum / Heinrich Walt -- Plants and plant-derived products as cancer chemopreventive agents / Douglas M. Noonan, Ilaria Sogno, and Adriana Albini -- From standard tanacetum parthenium extract to a stabilized derivative of parthenolide : studies in animal models of pain / Rosaria Greco ... [et al.] -- Antiviral effects of essential oils used traditionally in phytomedicine / JuÌ?rgen Reichling and Paul Schnitzler -- The neuroprotective capacity of achyrocline satureioides (Lam) D.C. and its flavonoids : mechanisms of action / Federico Dajas ... [et al.] -- Recent progress in echinacea research / Karin Woelkart and Rudolf Bauer -- Contribution of herbal medicine to human health : a brief history / Luigi Antonio Morrone ... [et al.] -- Quality issues of current herbal medicines / Paola Montoro, Sonia Piacente, and Cosimo Pizza -- Herbal medicines in the developing world : South America / Federico Dajas and Felicia Rivera-Megret -- Herbal medicines : epidemiology of their utilization, a perspective on the industrialized world / Anna Loraschi and Marco Cosentino."

"Il termine panax ginseng evoca la panacea, nome dato dagli antichi a piante dalle grandi proprietà terapeutiche. Mentre il nome cinese si traduce all’incirca come “uomo dalle gambe allargate”, il mistero circa le le sue origini lo avvicinano storicamente alla celebre radice di mandragora dalle forme antropomorfe. Questa pianta dall’effetto rinforzante ha molte altre virtù e proprietà biologiche, di cui il potenziale terapeutico e immunostimolante è notevole. Come tutta una serie di piante denominate adattogene, è la diretta concorrente di un’altra tra le araliaceae, il ginseng americano o panax quinquefolium. Cosa sappiamo del Ginseng? Rari sono i casi di piante così ampiamente studiate dal punto di vista medico e scientifico. Questa opera fornisce un’ampia panoramica delle conoscenze a disposizione, dagli studi classici ai dati scientifici più aggiornati, proponendo una definizione della parola adattogena, fino ad oggi mancante. Il volume cataloga inoltre le altre piante dette adattogene precisando in cosa esse si differenziano dal ginseng."

"This handbook paves the way to success in plant-based drug development, systematically addressing the issues facing a pharmaceutical scientist who wants to turn a plant compound into a safe and effective drug. Plant pharmacologists from around the world demonstrate the potentials and pitfalls involved, with many of the studies and experiments reported here."

"[

Telah dilakukan penelitian makrozoobentos di Situ Agathis dan Situ Mahoni masing-masing pada 2014 dan 2010. Penelitian ini bertujuan untuk mengukur komposisi, keanekaragaman, kemerataan, dan dominasi, kemudian mengukur nilai kesamaan kedua komunitas makrozoobentos. Penelitian dilakukan pada bulan Agustus 2024. Setiap perairan dibagi menjadi 3 titik berdasarkan arah aliran air, yaitu inlet, midlet, dan outlet. Sampel makrozoobentos diperoleh dengan ekman grab dan jaring. Parameter air yang diukur adalah suhu, keasaman, turbiditas, kecerahan, dan kadar DO (dissolved oxygen). Komunitas makrozoobentos masing-masing perairan dianalisis dengan indeks keanekaragaman Shannon-Wiener, indeks kemerataan, dan indeks dominasi Simpson. Komunitas kedua perairan dibandingkan dengan menghitung indeks kesamaan Sorensen. Teramati 8 spesies makrozoobentos selama penelitian: Pomacea canaliculata, Filopaludina javanica, Pila scutata dan Lymnaea rubiginosa teramati pada kedua perairan. Gyraulus convexiusculus dan Indoplanorbis exustus hanya teramati di Situ Agathis. Melanoides tuberculata, dan Parathelphusa Bogoriensis hanya teramati di Situ Mahoni. Hasil penelitian di Situ Agathis dan Situ Mahoni menunjukan bahwa nilai keanekaragaman rata-rata adalah sedang, nilai kemerataan rata-rata adalah tinggi, nilai dominasi rata-rata adalah rendah, dan nilai kesamaan antara kedua komunitas adalah 67%. Parameter air air yang tidak ideal untuk makrozoobentos memiliki dampak negatif terhadap keanekaragaman komunitas makrozoobentos.

---

There have been previous studies on the communities of macrozoobenthos in lake Agathis and lake Mahoni in 2014 and 2010 respectively. This study aims to measure the diversity, eveness, and dominance level of macrozoobenthos communities in both lakes. Sampling is done on August 2024. Each lake is divided into 3 spots based on the flow of the water; inlet, midlet, and outlet. Makrozoobentos samples are obtained with an ekman grab and a net. The water parameters measured are temperature, acidity, turbidity, clarity, and dissolved oxygen levels. Eack macrozoobenthos community is analyzed with the Shanno-Wiener diversity index, the eveness index, and the Simpson dominance index. Both communities are compared with the Sorensen similarity index. Eight species of makrozoobentos are observed in the study. Pomacea canaliculata, Filopaludina javanica, Pila scutata and Lymnaea rubiginosa are found in both lakes. Gyraulus convexiusculus and Indoplanorbis exustus are only found in lake Agathis. Melanoides tuberculata and Parathelphusa Bogoriensis are only found in lake Mahoni. The study finds that lake Agathis and lake Mahoni have an average level of diversity, a high eveness value, a low dominance value, and have a 67% similarity value. Unideal water parameters have a negative effect on the diversity of macrozoobenthic communities.

;, ]"

"Sistem penghantaran obat ke kolon merupakan salah satu solusi alternatif untuk pengobatan terkait penyakit di kolon, salah satunya dalam mengobati fibrosis kolon. Salah satu obat yang digunakan untuk antifibrosis adalah tetrandrine. Tujuan dari penelitian ini adalah membuat dan mengkarakterisasi beads kitosan-tripolifosfat tetrandrine dengan metode gelasi ion dengan variasi konsentrasi larutan sambung silang tripolifosfat 3% (Formula 1), 4% (Formula 2), dan 5% (Formula 3). Karakterisasi beads diuji dengan scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffraction, moisture content, dan uji daya mengembang. Beads yang telah terbentuk berwarna kuning keemasan dengan ukuran rata-rata 907 ? 944 μm untuk formula 1, 900 - 973 μm untuk Formula 2, dan 1003 ? 1028 μm untuk Formula 3. Dari hasil karakterisasi Formula 3 merupakan formula yang terbaik dan digunakan untuk penyalutan. Beads Formula 3 dilakukan penyalutan menggunakan Eudragit L100-55 dan Eudragit L100 dengan masing-masing konsentrasi Eudragit L100-55 10% (Formula 3A), Eudragit L100-55 12,5% (Formula 3B), Eudragit L100 10% (Formula 3C), dan Eudragit L100 12,5% (Formula 3D). Pada uji pelepasan obat pada beads yang telah disalut, dilakukan dalam medium HCl pH 1,2 (2 jam), dapar fosfat pH 7,4 (3 jam), dan dapar fosfat pH 6,8 (3 jam). Hasil pelepasan kumulatif obat pada Formula 3A, Formula 3B, Formula C, dan Formula D secara berturut-turut adalah sebesar 40,15%, 37,97%, 45,85%, dan 41,70%. Berdasarkan hasil yang diperoleh, Formula 3C adalah formula yang paling baik dalam melepas tetrandrine di medium dapar fosfat 6,8 karena berhasil melepaskan obat yang paling besar diantara formula yang lain. Selain itu juga Formula 3C juga telah berhasil menjaga keberadaan beads ketika melewati lambung tikus yang telah diuji melalui uji pentargetan secara in vivo.

---

Drug delivery to the colon is an alternative solution for treatment in colon which one is fibrosis. Tetrandrine is a drug that has anti-fibrosis effects. The aim of this research was preparation and charactherization of chitosan-tripolyphosphate tetrandrine beads which was prepared by ionic gelation method with variation in sodium tripolyphosphate concentration 3% (Formula 1), 4% (Formula 2), and 5% (Formula 3). The characteristics of beads were investigated by scanning electron microscopy (SEM), differential scanning calorimetry (DSC), X-ray diffraction, moisture content, release studies, and swelling measurements. Beads was produced are yellow-gold colour which has average size of beads, 907 ? 944 μm, 900 - 973 μm, and 1003 ? 1028 μm for formula 1, 2, 3, respectively.

The result of characterization, Formula 3 was the best formula. Formula 3 was coated with Eudragit L100-55 and Eudragit L100 with several concentrations; Eudragit L100-55 10% (Formula 3A), Eudragit L100-55 12,5% (Formula 3B), Eudragit L100 10% (Formula 3C), and Eudragit L100 12,5% (Formula 3D). Drug release tests conducted in the medium pH 1.2 (2 hours), phosphate buffer pH 7.4 (3 hours), and phosphate buffer pH 6 (3 hours).

The results of drug release was 40.15%, 37.97%, 45.85%, 41.70% for Fornula 3A, 3B, 3C, 3D, respectively. Based on these results can be concluded that Formula 3C was the best formulation which has higher drug release than others. Additionally, Formula 3C also had managed to keep the existence of beads when passing through the stomach of rat that have been tested through in vivo targeting test.

"