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"Penyakit kanker merupakan salah satu penyebab kematian dengan angka mortalitas tertinggi. Penelitian ini melaporkan profil pasien kanker yang berdomisili di wilayah Jakarta Utara dan Kepulauan Seribu tahun 2008 ndash; 2012 dengan total 2185 penderita kanker, terdiri dari 740 laki-laki dan 1445 perempuan. Mayoritas pasien bekerja sebagai ibu rumah tangga. Distribusi stadium kanker terbanyak adalah pada stadium 3. Urutan lima kanker terbanyak adalah kanker payudara, kanker serviks, kanker nasofaring, keganasan sistem hematopoetik dan retikuloendotelial, dan kanker ovarium. Pada laki-laki kanker terbanyak adalah kanker nasofaring, sedangkan pada perempuan kanker terbanyak adalah kanker payudara. Distribusi usia pada lima kanker terbanyak adalah pada kelompok 45-54 tahun kecuali sistem hematopoetik dan retikuloendotelial kelompok usia terbanyak pada

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Cancer is one cause of death with the highest mortality rate. This study reports the profile of cancer patients living in North Jakarta and the Thousand Islands of 2008 to 2012 with a total of 2185 cancer patients, consisting of 740 men and 1445 women. The majority of patients work as housewives. The highest stage of cancer distribution is in stage 3. The top five cancer sequences are breast cancer, cervical cancer, nasopharyngeal cancer, hematopoietic and reticuloendothelial system malignancy, and ovarian cancer. In males most cancer is nasopharyngeal cancer, whereas in most cancer women is breast cancer. The age distribution of the five most common cancers is in the 45 54 year group except the hematopoietic and reticuloendothelial system of the most age group at "

"Kanker serviks di Indonesia berdasarkan keganasan pada jenis kelamin wanita, menempati urutan ke 2 dengan prevalensi sebesar 14,4 dan angka mortalitas sebesar 10,3. Dari sisi pembiayaan, pengobatan kanker menempati urutan kedua besar anggaran yang di keluarkan oleh BPJS Kesehatan. Data registrasi kanker sangat dibutuhkan untuk evaluasi dan membuat kebijakan yang tepat guna di rumah sakit dalam rangka meningkatkan kualitas pelayanan kanker. Hospital Based Cancer Registry HBCR merupakan suatu sistem registrasi kanker yang dilakukan di rumah sakit yang dapat menyediakan informasi mengenai informasi umum dari pasien kanker, pengobatan serta hasil dari pengobatan. Penelitian ini dilakukan untuk memperoleh profil kanker serviks di RSCM tahun 2013 berdasarkan data hospital based cancer registry. Penelitian dilakukan dengan mengekstraksi data epidemiologi dan data tumor serviks dari HBCR RSCM tahun 2013 yang kemudian dilakukan analisa deskriptif. Dari hasil penelitian didapatkan bahwa kanker serviks menempati urutan kedua terbanyak dari seluruh keganasan di RSCM 12 ,n= 678, dengan domisili sebagian besar berasal dari luar DKI Jakarta 52,8, n = 358. Usia rata-rata terjadinya kanker serviks adalah 49,48 tahun, tersering terjadi pada rentang usia 45-49 tahun. Dari sisi histopatologi, karsinoma sel skuamosa merupakan jenis histopatologi pada kanker serviks yang paling banyak dijumpai 74,2, n = 447. Tindakan operasi merupakan jenis tindakan yang paling banyak dilakukan pada kanker serviks stadium dini 83,3, n=25, sedangkan tindakan radiasi paling banyak dilakukan pada kanker serviks stadium lokal lanjut 79,9, n=273 .

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Cervical cancer ranks at the second place based on the malignancy among female sex in Indonesia with a prevalence of 14.4 and a mortality rate of 10.3. From a financial perspective, the treatment of cancer ranks second big budget expended by the Indonesian national health insurance. Cancer registration data are needed to evaluate and make appropriate policy in hospitals in order to improve the quality of cancer services. Hospital Based Cancer Registry HBCR is a system of cancer registration in a hospital that can provide information about the general information of cancer patients, treatment, and outcome of treatment. This study was conducted to obtain the profile of cervical cancer in the RSCM in 2013 based on data from RSCM hospital based cancer registry. The study was conducted by extracting the epidemiological data and cervical tumor data from HBCR RSCM in 2013 which was then analyzed descriptively.

The result showed that cervical cancer ranks at the second place from all the malignancy at RSCM 12, n 678, with domicile mostly come from outside Jakarta 52.8, n 358. The average age of cervical cancer was 49.48 years, the most common occurs in the age range 45 49 years. In terms of histopathology, squamous cell carcinoma is the most prevalence type of histopathology of cervical cancer 74.2, n 447. The surgery is a type of action that done for early stage cervical cancer 83,3, n 25, whereas the action of radiation are mostly done in locally advanced cervical cancer 79,9, n 273."

"Kanker merupakan penyebab kematian utama pada negara maju maupun berkembang. Untuk menentukan arah kebijakan rumah sakit dan sebagai basis penelitian di bidang kanker, diperlukan data komprehensif mengenai epidemiologi kanker di Rumah Sakit Cipto Mangunkusumo. Penelitian ini memberikan gambaran profil epidemiologi kanker di Rumah Sakit Cipto Mangunkusumo berdasarkan Registrasi Kanker Berbasis Rumah Sakit RSCM tahun 2013 sebagai berikut. Frekuensi kanker di RSCM pada tahun 2013 adalah 5.554 kasus kanker. Data demografi pasien kanker di RSCM tahun 2013 adalah: mayoritas pasien berusia 45-54 tahun secara keseluruhan, 45-54 tahun untuk wanita dan 55-64 tahun untuk laki-laki. Jumlah pasien perempuan dibandingkan laki-laki adalah 1,5:1. Selama tahun 2013, RSCM lebih banyak melayani pasien kanker dari luar Jakarta dibandingkan dari Jakarta dan pekerjaan yang paling banyak adalah ibu rumah tangga. Secara keseluruhan, kanker payudara, serviks dan leukemia merupakan jenis kanker tersering. Untuk jenis kelamin perempuan yang tersering adalah payudara, serviks dan ovarium. Untuk jenis kelamin laki-laki yang tersering adalah leukemia, nasofaring dan kegasanan kelenjar getah bening limfoma. Sebagian besar pasien kanker payudara dan serviks datang dalam stadium lokal lanjut dan lanjut. Jenis histopatologi yang paling sering dari 3 kasus kanker terbanyak di RSCM tahun 2013 adalah : Karsinoma duktal invasif payudara, karsinoma sel skuamosa tak berkeratin serviks, leukemia limfoblastik akut leukemia.

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Cancer is the leading cause of death in developed and developing countries. To determine the direction of hospital policy and to provide basic data in aiding cancer research, comprehensive cancer epidemiology profile in Cipto Mangunkusumo Hospital is needed. This study provides an overview of cancer epidemiology profile at Cipto Mangunkusumo based on Hospital based Cancer Registry in 2013. The result is as follows frequency of cancer in RSCM in 2013 were 5,554 cancer cases. The demography data of cancer patients in RSCM in 2013 were the majority of patients aged 45 54 overall, 45 54 for women and 55 64 for men. The number of female patients compared with males was 1.5 1. During the year 2013, RSCM serve more cancer patients from outside of Jakarta than from Jakarta, most frequent jobs were housewives.

Overall, breast cancer, cervical cancer and leukemia is the most common cancer type. For female, the most common cancer cases are breast, cervical and ovarian. For male, the most common cancer cases are leukemia, nasopharynx and lymph nodes lymphoma. The majority of breast and cervical cancer patients seeks help in locally advanced and advanced stages. Most common Histopathological typewere invasive ductal carcinoma breast, non keratinized squamous cell carcinoma cervical, acute lymphoblastic leukemia leukemia ."

"[ABSTRAKPenelitian ini bertujuan untuk mengetahui gambaran umum kanker ovarium di Rumah Sakit Ciptomangunkusumo (RSCM) 5 tahun terakhir beserta faktor-faktor yang berhubungan dengan kanker ovarium. Penelitan ini mengambil data pasien kanker ovarium selain tipe borderline yang terdapat di Cancer Registry divisi Ginekologi Onkologi dan masih memiliki rekam medis di RSCM pada periode Januari 2010 – Desember 2014, dilakukan follow up untuk mengetahui kesintasan hidup selama 4 tahun. Kami mendapatkan 98 subyek penelitian. Pada penelitian ini didapatkan insidensi kanker ovarium terbanyak pada usia 45-54 tahun (33,6%), insidensi kanker ovarium menurun dengan bertambahnya jumlah anak, sebagian besar kanker ovarium merupakan tipe epitelial (76,5%) dan sebagian besar pasien didiagnosa pada stadium lanjut (55.1%). Kesintasan hidup 4 pasien kanker ovarium tipe epitelial 77%; tipe germinal 83.3%; tipe stroma 100%. Kesintasan hidup 4 tahun dengan terapi pembedahan 84.1%; pembedahan disertai kemoterapi adjuvan 83.3%; kemoterapi neoadjuvan sebelum pembedahan 68.4%. Terdapat 63% respon komplit pada kelompok kemoterapi adjuvan; dan 41.2% pada kelompok kemoterapi neoadjuvan.

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ABSTRACTThe aim of this research is to describe the incidence of ovarian cancer and its characteristic in Ciptomangunkusumo Hospital in the last 5 year. The data was collected from Gynecology Oncology Division’s Cancer Registry and RSCM’s medical record from Januari 2010 – December 2014, follow up was performed to know the survival. There was 98 subject in this research. The result was : majority incidence of ovarian cancer was in the age 45-54 years old (33,6%); ovarian cancer incidence decrease in parity’s group; the majority histotype was epithelial (76.5%); and most of them were diagnosed on advanced stage (55.1%). The 4 year survival rate for epithelial was 77%; germinal was 83,3%; and stromal was 100%. Based on therapy the 4 year survival rate was 84.1%; 83.3% in adjuvant chemotherapy group; and 68.4% in neoadjuvan chemotherapy. In the group of adjuvant chemotherapy there was 63% complete respon and 41.2% in neoadjuvan chemotherapy.;The aim of this research is to describe the incidence of ovarian cancer and its characteristic in Ciptomangunkusumo Hospital in the last 5 year. The data was collected from Gynecology Oncology Division’s Cancer Registry and RSCM’s medical record from Januari 2010 – December 2014, follow up was performed to know the survival. There was 98 subject in this research. The result was : majority incidence of ovarian cancer was in the age 45-54 years old (33,6%); ovarian cancer incidence decrease in parity’s group; the majority histotype was epithelial (76.5%); and most of them were diagnosed on advanced stage (55.1%). The 4 year survival rate for epithelial was 77%; germinal was 83,3%; and stromal was 100%. Based on therapy the 4 year survival rate was 84.1%; 83.3% in adjuvant chemotherapy group; and 68.4% in neoadjuvan chemotherapy. In the group of adjuvant chemotherapy there was 63% complete respon and 41.2% in neoadjuvan chemotherapy.;The aim of this research is to describe the incidence of ovarian cancer and its characteristic in Ciptomangunkusumo Hospital in the last 5 year. The data was collected from Gynecology Oncology Division’s Cancer Registry and RSCM’s medical record from Januari 2010 – December 2014, follow up was performed to know the survival. There was 98 subject in this research. The result was : majority incidence of ovarian cancer was in the age 45-54 years old (33,6%); ovarian cancer incidence decrease in parity’s group; the majority histotype was epithelial (76.5%); and most of them were diagnosed on advanced stage (55.1%). The 4 year survival rate for epithelial was 77%; germinal was 83,3%; and stromal was 100%. Based on therapy the 4 year survival rate was 84.1%; 83.3% in adjuvant chemotherapy group; and 68.4% in neoadjuvan chemotherapy. In the group of adjuvant chemotherapy there was 63% complete respon and 41.2% in neoadjuvan chemotherapy., The aim of this research is to describe the incidence of ovarian cancer and its characteristic in Ciptomangunkusumo Hospital in the last 5 year. The data was collected from Gynecology Oncology Division’s Cancer Registry and RSCM’s medical record from Januari 2010 – December 2014, follow up was performed to know the survival. There was 98 subject in this research. The result was : majority incidence of ovarian cancer was in the age 45-54 years old (33,6%); ovarian cancer incidence decrease in parity’s group; the majority histotype was epithelial (76.5%); and most of them were diagnosed on advanced stage (55.1%). The 4 year survival rate for epithelial was 77%; germinal was 83,3%; and stromal was 100%. Based on therapy the 4 year survival rate was 84.1%; 83.3% in adjuvant chemotherapy group; and 68.4% in neoadjuvan chemotherapy. In the group of adjuvant chemotherapy there was 63% complete respon and 41.2% in neoadjuvan chemotherapy.]"

"Satu dari tujuh kematian di dunia disebabkan karena kanker. Beban akibat kanker di masa depan diprediksikan akan terus meningkat terutama di negara berkembang termasuk Indonesia. Penelitian ini melaporkan profil epidemiologi penyakit kanker di RSUPN Cipto Mangunkusumo tahun 2011-2012 berdasarkan data Registrasi Kanker Berbasis Rumah Sakit, dengan total 7399 penderita kanker, terdiri dari 2794 laki-laki dan 4605 perempuan. 54.52 penderita berasal dari luar Jakarta. Rentang usia tersering adalah 45-54, 35-44 dan 55-64 tahun. Mayoritas pasien bekerja sebagai ibu rumah tangga, pekerja kantor, dan pedagang. Pada laki-laki, penyakit kanker tersering adalah nasofaring, sistem hematopoetik dan retikuloendotelial, kelenjar getah bening, hepar dan duktus bilier, dan rektum, sedangkan perempuan, serviks uteri, payudara, ovarium, sistem hematopoetik dan retikuloendotelial, dan tiroid dengan mayoritas rentang usia diantara 45-54 tahun, kecuali keganasan sistem hematopoetik dan retikuloendotelial tersering pada usia 5-14 tahun. Kanker nasofaring dan kelenjar getah bening lebih banyak diderita oleh laki-laki, sedangkan keganasan sistem hematopoetik dan retikuloendotelial cukup seimbang jumlahnya antara laki-laki dan perempuan. Sebagian besar penyakit kanker ditemukan pada stadium 3 dan 4. Berdasarkan morfologi tersering, kanker serviks uteri dan nasofaring adalah neoplasma ganas, karsinoma payudara duktal invasif, leukemia prekursor sel limfoblastik dan limfoma non Hodgkin.

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One in seven deaths in the world is due to cancer. The future burden of cancer is predicted to keep rising, especially in developing countries including Indonesia. This study reports on cancer epidemiological profile in Cipto Mangunkusumo National Hospital year 2011 2012 based on Hospital Based Cancer Registry data, with a total of 7399 cancer patients consists of 2794 male and 4605 female. 54.52 patients are from outside Jakarta. Most common age range are 45 54, 35 44 and 55 64 years old. Majority of the patients are housewives, officers, and merchants. In male, the leading sites of cancer are nasopharyngeal, the hematopoietic and reticuloendothelial system, lymph nodes, liver and biliary duct, and rectum, whereas in women there are uterine cervix, breast, ovary, the hematopoietic and reticuloendothelial system, and thyroid with the majority of age between 45 54 years old, except malignancy of the hematopoietic and reticuloendothelial systems are more common in the age range of 5 14. Nasopharyngeal and lymph nodes malignancies are more common in men, whereas the hematopoietic system and reticuloendothelial malignancy is quite balanced between male and female cases. Mostly there are at stage 3 and 4. Based on the most common morphologies, uterine cervix and nasopharyngeal are malignant neoplasms, invasive ductal carcinoma of breast, precursor cell lymphoblastic leukemia and non Hodgkin 39 s lymphoma."