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"ABSTRAKPenelitian yang membahas hubungan antara seng dan derajat keparahan akne masih terbatas dengan hasil yang tidak konsisten antara satu penelitian dengan penelitian yang lain. Penelitian ini merupakan penelitian potong lintang komparasi untuk menilai hubungan asupan seng dan konsentrasi seng serum dengan derajat keparahan akne vulgaris berdasarkan kriteria Indonesian Acne Expert Meeting. Dilakukan penilaian asupan seng dan pemeriksaan konsentrasi seng serum terhadap 60 pasien akne vulgaris di Rumah Sakit Cipto Mangunkusumo. Analisis data asupan seng terhadap derajat keparahan akne menggunakan uji T tidak berpasangan sedangkan analisis data konsentrasi seng serum terhadap derajat keparahan akne menggunakan uji Mann-Whitney. Pada penelitian ini, asupan seng pada seluruh subjek berada dibawah nilai Angka Kecukupan Gizi Indonesia dan rerata asupan seng pada kelompok akne ringan lebih tinggi dibandingkan kelompok akne derajat sedang berat. Konsentrasi seng serum pada kelompok akne ringan lebih tinggi dibandingkan kelompok akne derajat sedang berat. Ditemukan perbedaan yang bermakna antara asupan seng pada kelompok akne derajat ringan dengan kelompok akne derajat sedang berat, dan konsentrasi seng serum antara kelompok akne derajat ringan dengan kelompok akne derajat sedang berat.

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ABSTRACTZinc recently known to have an effect on reducing the severity of acne, but this finding was still inconsistent between one study to another. A comparation cross sectional study was conducted to assess the association of zinc intake and serum zinc level with the severity of acne based on Indonesian Acne Expert Meeting criteria. A total of 60 acne patients in Cipto Mangunkusumo Hospital were selected. Data analysis on zinc intake on acne severity using unpaired T test while zinc serum concentration on acne severity with Mann Whitney test. In this study, zinc intake in all subjects was below the Indonesian Recommended Daily Allowance and mean of zinc intake in mild acne group was higher compare to the moderate severe acne group. Zinc serum level in mild acne group was higher compare to the moderate severe acne group. There was a significant difference between zinc intake in mild and moderate severe acne group, and zinc serum level between mild and moderate severe acne group."

"Akne vulgaris (AV) merupakan kelainan kulit menahun folikel pilosebasea yang banyak dijumpai remaja dan dewasa muda. Beberapa penelitian melaporkan adanya hubungan antara seng dan AV. Penelitian dengan desain kasus kontrol ini bertujuan mencari hubungan kadar seng serum dengan derajat keparahan AV berdasarkan klasifikasi Lehmann dan dengan jumlah lesi inflamasi. Tujuh puluh subyek dengan AV, terdiri atas 35 AV ringan (AVR) [kelompok A] dan 35 AV sedang (AVS) dan AV berat (AVB) [kelompok B] berdasarkan klasifikasi Lehmann diperiksakan kadar seng serum yang diukur menggunakan Atomic absorption spectrophotometry. Hasil kadar seng serum kelompok A median (min-maks) 11,15 (10,23-14,21) μmol/L dan kelompok B median (min-maks) 9,93 (6,72-10,69) μmol/L. Kadar seng serum kelompok A lebih tinggi dibandingkan kelompok B (p<0,001). Terdapat korelasi negatif yang bermakna antara kadar seng serum dengan jumlah lesi inflamasi pada AV(r -0,488). Sebagai tambahan didapatkan korelasi negatif kadar seng serum dengan jumlah lesi non inflamasi (r-0,582) ataupun total lesi AV (r-0,662). Hasil penelitian ini membuktikan bahwa kadar seng serum berhubungan dengan derajat keparahan AV menurut klasifikasi Lehmann, yakni kadar seng serum lebih rendah pada AV derajat berat dan sedang dibandingkan derajat ringan, dan sejalan dengan hubungannya terhadap jumlah lesi, baik inflamasi, non inflamasi, dan total lesi.

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Acne vulgaris (AV) is a chronic cutaneous disorder in pilosebaceous follicles affecting many of the adolescents and young adults. Several studies have reported an association between serum zinc level and acne vulgaris. This case-control study aimed to find the relationship between serum zinc level with severity of AV according on Lehmann?s classification and the number of inflamatory lesions. Seventy AV subjects, consisting of 35 subjects with mild AV (Group A) and 35 subjects with moderate and severe AV (Group B) based on Lehmann's classification are measured their serum zinc levels with Atomic absorption spectrophotometry. In group A serum zinc level median (min-max) was 11,15 (10,23-14,21) μmol/L and in group B, median (min-max) was 9,93 (6,72-10,69) μmol/L. Serum zinc levels in group A were statistically significant higher than group B (𝑃𝑃<0,001). There was a negative correlation between serum zinc levels with the number of inflammatory lesions (r-0,488). Additional result obtained were negative correlation between serum zinc levels with number of non-inflammatory lesions (r-0,582) and total lesion of AV (r-0,662). The results of this study proved that serum zinc levels was associated with the severity of AV according to Lehmann's classification,i.e. serum zinc levels were lower in severe and moderate acne compared with mild acne, and in line with its correlation to number of lesions, either inflammatory, non-inflammatory, and total lesions."

"Latar Belakang: Akne vulgaris AV adalah peradangan kronis pilosebasea yang terutama dijumpai pada remaja dan dewasa muda. Peranan diet pada patogenesis AV terus menjadi perdebatan. Salah satu mikronutrien yang diduga berperan dalam patogenesis AV adalah vitamin A atau retinol. Tujuan: Mengetahui kadar retinol serum dan korelasinya dengan derajat keparahan AV, serta asupan vitamin A pasien AV. Metode: Studi potong lintang dengan 20 subjek penelitian SP yang direkrut secara consecutive sampling. Kadar retinol serum diukur menggunakan high performance liquid chromatography HPLC, sedangkan asupan vitamin A dinilai dengan metode food frequency questionnaire FFQ semikuantitatif. Hasil: Rerata kadar retinol serum kelompok AVR, AVS, dan AVB yaitu 0,962 SB 0,145 mol/L, 0,695 SB 0,054 mol/L, dan 0,613 SB 0,125 mol/L. Terdapat korelasi bermakna antara kadar retinol serum dengan derajat keparahan AV r = -0,798, p = 0,000. Rerata asupan vitamin A per hari pada kelompok AVR, AVS, dan AVB sebesar 476,21 SB 221,32 g, 823,71 SB 221,32 g, dan 780,99 SB 530,45 g. Simpulan: Kadar retinol serum ditemukan rendah pada kelompok AVS dan AVB. Hasil penelitian ini membuktikan semakin rendah kadar retinol serum, semakin berat derajat keparahan AV. Tidak terdapat perbedaan asupan vitamin A di antara ketiga kelompok.

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Background: Acne vulgaris AV is a chronic inflammation of pilosebaceus that is primarily found in adolescents and young adults. The role of diet in the pathogenesis of AV continues to be a debate. One of micronutrients alleged in the pathogenesis of AV is vitamin A or retinol.

Objective: This study aims to know the levels of serum retinol and its correlation with the degree of severity of the AV, as well as the patient 39 s intake of vitamin A.

Method: This cross sectional study included 20 subjects divided into mild, moderate, and severe groups based on Lehman rsquo s classification. Serum retinol levels measured using high performance liquid chromatography, whereas the intake of vitamin A was assessed by semiquantitative food frequency questionnaire method.

Results: The mean serum retinol levels of mild, moderate, and severe groups were respectively 0.962 SD 0.145 mol L, 0.695 SD 0.054 mol L, and 0.613 SD 0.125 mol L. There was significant correlation between serum retinol levels with the degree of severity of the AV r 0.798, p 0.000. The mean intake of vitamin A per day of mild, moderate, and severe groups were respectively 476.21 SD 221.32 g, 823.71 SD 221.32 g, and 780.99 SD 530.45 g.

Conclusion: Levels of serum retinol found lower on the moderate and severe groups. The results has proven that the lower the levels of serum retinol, the more severe the degree of severity of the AV. There was no difference in vitamin A intake among the three groups."

"Salah satu faktor yang menentukan BB lahir bayi adalah asupan nutrisi ibu yang adekuat. Beberapa nutrien diketahui memiliki efek terhadap BB lahir bayi di antaranya adalah protein dan seng. Desain penelitian ini adalah cross-sectional dan dilakukan di 10 puskesmas kecamatan di Jakarta Timur sejak Februari hingga April 2015 dengan subjek ibu hamil berusia 19–44 tahun dengan usia kehamilan 32–37 minggu. Data asupan protein didapatkan dengan metode 24-hour recall, sedangkan asupan seng dengan metode Semi Quantitative Food Frequency Questionnaire dan 24-hour recall. Pengambilan darah dilakukan sebelum ibu melahirkan dan diperiksa dengan metode Atomic Absorption Spectrophotometry. Berat badan lahir bayi diukur segera setelah bayi lahir. Sebanyak 116 subjek mengikuti penelitian hingga akhir. Analisis statistik menunjukkan tidak terdapat korelasi antara asupan protein dengan kadar seng serum (r = 0,042, p = 0,653), tidak terdapat korelasi antara asupan seng dengan kadar seng serum (r = 0,155, p = 0,096), tidak terdapat korelasi antara asupan seng dengan BB lahir bayi (r = - 0,09, p = 0,303), dan tidak terdapat korelasi antara kadar seng serum dengan BB lahir bayi (r = -0,116, p = 0,215). Penelitian ini belum berhasil menemukan hubungan antara asupan protein, seng, dan kadar seng serum dengan BB lahir bayi.

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One of the factors affecting birth weight is mother’s adequate nutrient intake. Several nutrients are known to its effect to birth weight, which among them are protein and zinc. A cross-sectional study was conducted in 10 district public health centres in East Jakarta since Februari until April 2015. Subjects of the study were pregnant mothers aged 19–44 years old whose gestational age between 32–37 weeks.

Protein intake was computed based on 24-hour recall method, while zinc intake was computed based on Semi Quantitative Food Frequency Questionnaire and 24-hour recall method. Blood specimens were collected before giving birth and being assesed by Atomic Absorption Spectrophotometry method. Birth weight was measured soon after the baby was born. One hundred and sixteen subjects followed the study until the end.

Statistical analysis showed there were no correlation between protein intake and maternal zinc serum (r = 0,042, p = 0,653), no correlation between zinc intake and maternal zinc serum (r = 0,155, p = 0,096), no correlation between zinc intake and birth weight (r = -0,09, p = 0,303), and no correlation between maternal zinc serum and birth weight (r = - 0,116, p = 0,215). This study has not been able to prove any relationship between maternal intake of protein, zinc, zinc serum and birth weight."

"Latar belakang dan tujuan: Akne vulgaris AV merupakan inflamasi kronik pada unit pilosebasea. Beberapa penelitian telah meneliti kadar 25-hydroxyvitamin D [25 OH D] serum pada pasien AV dengan hasil bervariasi, namun umumnya rendah. Kadar vitamin D diduga terpengaruh oleh pajanan sinar matahari, letak geografis, ras/tipe kulit, dan asupan makanan, sehingga mungkin temuan di Indonesia akan berbeda daripada penelitian terdahulu di luar negeri. Penelitian ini bertujuan untuk mengetahui kadar 25 OH D serum dan hubungan dengan derajat keparahan, lesi inflamasi, noninflamasi, dan total lesi AV. Metode: Penelitian potong lintang ini melibatkan 30 subjek penelitian SP, direkrut secara consecutive sampling, terbagi rata ke dalam kelompok AV ringan AVR, AV sedang AVS, dan AV berat AVB berdasarkan klasifikasi Lehmann. Faktor risiko AV yang berkaitan dengan vitamin D pajanan sinar matahari, penggunaan tabir surya, suplementasi, jumlah lesi, dan kadar 25 OH D serum dinilai pada seluruh SP. Hasil : Median kadar 25 OH D serum pada kelompok AVR, AVS, dan AVB yaitu 16,3 9,1- 17,8 ng/mL, 12,7 9,6-15,6 ng/mL, dan 9,35 4,9-10,9 ng/mL Median pada kelompok AVR dan AVS lebih tinggi dibandingkan AVB.

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Background and objective: Acne vulgaris AV is chronic inflammation of pilosebaceous units. Several studies have investigated the levels of serum 25 hydroxyvitamin D 25 OH D in AV patients with varying outcomes, but mostly decreased. Vitamin D levels are thought to be affected by sun exposure, geographical location, race skin type, and food intake, that research in Indonesia may yield different results. This study aimed to determine the level of serum 25 OH D and its association with the severity and the number of inflammatory, noninflammatory, and total AV lesions.

Methods: This cross sectional study included 30 patients. Subjects were recruited by consecutive sampling, grouped equally into mild, moderate, and severe AV based on Lehmann's classification. The risk factors for inadequate vitamin D such as sun exposures, sunscreen, and suplements, the number of lesions, and serum 25 OH D levels were assessed on all subjects.

Results: The median concentrations of serum 25 OH D in the three groups were respectively 16.3 9.1 17.8 ng mL, 12.7 9.6 15.6 ng mL, and 9.35 4.9 10.9 ng mL p."

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Akne vulgaris (AV) adalah penyakit inflamasi yang kronis pada bagian pilosebasea.  Pada umumnya akne terjadi pada masa pubertas, dewasa muda, dan banyak terjadi pada remaja. AV mempengaruhi 85% dewasa muda usia 12-25 tahun dan secara konsisten menduduki “the top three most prevalence skin condition“ dalam populasi umum Salah satu faktor yang mempengaruhi timbulnya akne vulgaris dan yang masih menjadi perebatan adalah faktor nutrisi. Dengan menggunakan cut-off <20 ng/mL, prevalensi defisiensi vitamin D bervariasi antara 6-70% di Asia Tenggara, hasil penelitian di Malaysia lebih dari setengah (58%) jumlah remaja memiliki 25(OH)D <50 nmol/L. Penelitian ini merupakan studi potong lintang yang membandingkan nilai rerata kadar vitamin D serum antara dua kelompok derajat akne pada remaja siswa sekolah menengah atas usia 15-18 tahun di kota Depok. Jumlah subjek total 60 orang terbagi dalam 2 kelompok, 30 orang kelompok akne vulgaris ringan (AVR) dan 30 orang akne vulgaris sedang-berat (AVS). Rerata kadar vitamin D serum subjek adalah 17,29±6,77 ng/ml. Sebanyak 21 subjek (35%) berada pada kondisi sufisiensi vitamin D dan 39 subjek (65%) berada dalam kondisi insufisiensi-defisiensi (terdiri dari 43,3% insufisiensi, 21,7% defisiensi). Kadar rerata vitamin D serum pada kelompok AVR 15,45±6,7 ng/ml dan pada AVS 19,13±6,8 ng/ml dengan p=0,034.

Kesimpulan : hasil penelitian ini menunjukkan ada hubungan yang bermakna antara kadar vitamin D serum dengan akne vulgaris. vitamin D serum.

 

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Acne vulgaris is a chronic inflammatory disease as a part of pilosebaceus. In general acne occurs during puberty, but it can also occur in young adults, and many occur in adolescents. Acne vulgaris affects 85% of young adults aged 12-25 years and consistently occupies "the top three most prevalence skin conditions" in the general population. One of the factors that influence acne vulgaris and which is still a debate pro and contra are nutritional factors. This study aims to find a relationship between vitamin D serum level and the degree of acne in adolescents. Previous researches that linked vitamin D levels with acne was not conclusive, especially in adolescents. This is a cross-sectional study that compares the mean values of serum vitamin D levels between two groups of acne levels in adolescents of high school students aged 15-18 years in the city of Depok. The total number of subjects was 60 people divided into 2 groups, 30 people in the group of mild acne vulgaris and 30 people with moderate-severe acne vulgaris. The mean of vitamin D level of the subject serum was 17.29 ± 6.77 ng / ml. The mean of vitamin D serum level in the mild group was 15.45 ± 6.7 ng / ml and moderate group was 19.13 ± 6.8 ng / ml with p = 0.034. A significant association was found between serum vitamin D levels and the degrees of acne vulgaris.

Conclusion: there is a significant relationship between serum vitamin D levels and degree of acne vulgaris. The mean of vitamin D level are lower in mild acne group than in moderate group

"

"Latar belakang: Akne vulgaris AV adalah penyakit kulit yang ditandai dengan terjadinya sumbatan dan peradangan kronik pada unit pilosebasea. Penelitian sebelumnya tentang kadar lipid darah pada pasien AV menunjukkan hasil yang bervariasi. Lipid darah diduga memengaruhi aktivitas kelenjar sebasea. Tujuan: Mengetahui korelasi antara kadar lipid darah dan kadar sebum dengan derajat keparahan AV, serta mengetahui korelasi kadar lipid darah dengan kadar sebum kulit wajah. Metode: Studi potong lintang ini dilakukan terhadap 30 pasien AV non-obesitas, yang terbagi berdasarkan tiga derajat keparahan AV. Dilakukan pemeriksaan kolesterol total, trigliserida, LDL, HDL darah dan kadar sebum kulit wajah pada SP. Hasil: Terdapat korelasi yang bermakna antara kadar sebum dengan derajat keparahan AV r = 0,6689, p = 0,0001 . Tidak terdapat korelasi antara kadar kolesterol total, trigliserida, LDL, HDL darah dengan derajat keparahan AV. Tidak terdapat korelasi antara sebum kulit wajah dengan kadar kolesterol total, trigliserida, LDL, HDL darah. Kesimpulan: Hasil penelitian ini menunjukkan bahwa kadar lipid darah tidak memengaruhi keparahan AV dan kadar sebum, sedangkan peningkatan kadar sebum kulit wajah dapat meningkatkan keparahan AV. Kata kunci: akne vulgaris; kadar sebum; lipid darah.

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Acne vulgaris is a common chronic skin disease involving blockage and inflammation of pilosebaceous units. Previous studies about blood lipids in acne patients revealed variable results. Blood lipids were considered affecting sebum production.

Objective: To identify the correlation between blood lipids, sebum excretion rate and acne severity. This study also determines the correlation between blood lipids and sebum excretion rate.

Methods: This study was conducted at Dr. Cipto Mangunkusumo Hospital in Jakarta. This was a cross sectional study with total of 30 non obese AV patients. The patients were divided into 3 groups based on the severity of AV. Total cholesterol, triglycerides, LDL, HDL serum and sebum excretion rate were measured.

Results: The results revealed significant correlation between sebum excretion rate and severity of acne vulgaris r 0,6689, p 0,0001 . There were no correlation between total cholesterol, LDL, triglycerides, HDL and acne severity. Blood lipids had no correlation with sebum excretion rate.

Conclusion: The results of this study has proven that blood lipids does not affect the severity of acne and sebum excretion rate. While increased sebum secretion would increase acne severity. Keywords acne vulgaris blood lipids sebum excretion."

"Latar belakang: Akne vulgaris AV adalah penyakit kulit yang ditandai dengan terjadinya sumbatan dan peradangan kronik pada unit pilosebasea. Penelitian sebelumnya tentang kadar lipid darah pada pasien AV menunjukkan hasil yang bervariasi. Lipid darah diduga memengaruhi aktivitas kelenjar sebasea. Tujuan: Mengetahui korelasi antara kadar lipid darah dan kadar sebum dengan derajat keparahan AV, serta mengetahui korelasi kadar lipid darah dengan kadar sebum kulit wajah. Metode: Studi potong lintang ini dilakukan terhadap 30 pasien AV non-obesitas, yang terbagi berdasarkan tiga derajat keparahan AV. Dilakukan pemeriksaan kolesterol total, trigliserida, LDL, HDL darah dan kadar sebum kulit wajah pada SP. Hasil: Terdapat korelasi yang bermakna antara kadar sebum dengan derajat keparahan AV r = 0,6689, p = 0,0001 . Tidak terdapat korelasi antara kadar kolesterol total, trigliserida, LDL, HDL darah dengan derajat keparahan AV. Tidak terdapat korelasi antara sebum kulit wajah dengan kadar kolesterol total, trigliserida, LDL, HDL darah. Kesimpulan: Hasil penelitian ini menunjukkan bahwa kadar lipid darah tidak memengaruhi keparahan AV dan kadar sebum, sedangkan peningkatan kadar sebum kulit wajah dapat meningkatkan keparahan AV.

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Background: Acne vulgaris is a common chronic skin disease involving blockage and inflammation of pilosebaceous units. Previous studies about blood lipids in acne patients revealed variable results. Blood lipids were considered affecting sebum production.

Objective: To identify the correlation between blood lipids, sebum excretion rate and acne severity. This study also determines the correlation between blood lipids and sebum excretion rate.

Methods: This study was conducted at Dr. Cipto Mangunkusumo Hospital in Jakarta. This was a cross sectional study with total of 30 non obese AV patients. The patients were divided into 3 groups based on the severity of AV. Total cholesterol, triglycerides, LDL, HDL serum and sebum excretion rate were measured.

Results: The results revealed significant correlation between sebum excretion rate and severity of acne vulgaris r 0,6689, p 0,0001 . There were no correlation between total cholesterol, LDL, triglycerides, HDL and acne severity. Blood lipids had no correlation with sebum excretion rate.

Conclusion: The results of this study has proven that blood lipids does not affect the severity of acne and sebum excretion rate. While increased sebum secretion would increase acne severity."

"Proses inflamasi pada kanker kepala dan leher menyebabkan peningkatan sitokin proinflamasi dan sintesis protein fase akut c-reactive protein, CRP yang kemudian menyebabkan perubahan metabolisme dan anoreksia pada penderitanya. Seng merupakan zat gizi yang memiliki peran penting dalam menekan inflamasi, namun dilaporkan sekitar 65 pasien kanker kepala dan leher mengalami kekurangan seng. Penelitian potong lintang ini bertujuan mengetahui korelasi antara asupan seng dan kadar seng serum dengan kadar c-reactive protein CRP sebagai upaya menekan inflamasi sehingga dapat mengurangi morbiditas dan mortalitas pasien kanker kepala leher. Dari 49 subyek yang dikumpulkan secara konsekutif di Poliklinik Onkologi RS Kanker Dharmais, 67,3 adalah laki-laki, rentang usia subyek 46 ndash;65 tahun. Frekuensi terbanyak 65,3 adalah kanker nasofaring dan 69,4 berada pada stadium IV. Seratus persen subyek memiliki asupan seng dibawah nilai angka kecukupan gizi. Rerata kadar seng serum subyek adalah 9,83 2,62 mol/L. Sebanyak 51 subyek memiliki kadar CRP yang meningkat. Terdapat korelasi negatif yang lemah antara kadar seng dengan kadar CRP subyek r =-0,292, p =0,042, namun tidak terdapat korelasi antara asupan seng dengan kadar CRP subyek p =0,86.

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The inflammatory process of head and neck cancer leads to increase the proinflammatory cytokines and the synthesis of c reactive protein CRP , which then causes metabolic alteration and anorexia in the patients. Zinc is one of nutrient that has an important role in suppressing inflammation. It is reported that about 65 of head and neck cancer patients have zinc deficiency. The aim of this cross sectional study is to determine the correlation between zinc intake and serum zinc levels with CRP level as an effort to reduce inflammation to reduce the morbidity and mortality of head and neck cancer patients. Subjects were collected by consecutive sampling in the Oncology Polyclinic Dharmais Cancer Hospital, from 49 subjects 67,3 were men, most subjects were in the age range between 46 ndash 65 years. The highest frequency 65,3 is nasopharyngeal cancer and 69,4 are already in stage IV. All subjects in this study have a zinc intake below the recommended dietary allowance RDA in Indonesia. The mean serum zinc level of the subjects was 9.83 2.62 mol L. Most subjects have elevated CRP levels. There was a weak significant negative correlation between zinc concentration and CRP levels of subjects r 0.292, p 0.042, but there was no correlation between zinc intake and CRP levels of subjects p 0.86. "

"[ABSTRAKPada kehamilan dibutuhkan asupan zat gizi yang adekuat untuk menunjangpembelahan sel dan pertumbuhan yang cepat. Seng merupakan kofaktor dari hampirsekitar 200 enzim yang berperan penting dalam embryogenesis. Defisiensi sengberhubungan dengan komplikasi pada ibu selama kehamilan dan persalinan sertagangguan pertumbuhan dan kelainan kongenital pada janin. Konsentrasi sengserum menurun sejak kehamilan trimester pertama hingga ketiga. Penelitian inimerupakan penelitian dengan desain potong lintang yang bertujuan untukmengetahui korelasi antara konsentrasi seng serum maternal dengan tali pusat padakehamilan trimester ketiga. Penelitian dilakukan di 10 puskesmas di Jakarta Timurpada bulan Maret 2015 sampai bulan April 2015. Pengambilan subyek dilakukandengan cara konsekutif dan didapatkan 63 orang subyek yang memenuhi kriteriapenelitian. Data dikumpulkan melalui wawancara meliputi data usia, usiakehamilan, paritas, pajanan rokok, pendapatan rumah tangga, pendidikan maternal,serta asupan protein, besi, tembaga dan seng dengan metode Food FrequencyQuestionnaire (FFQ) semikuantitatif. Pengukuran antropometri untuk menilaistatus gizi dan pemeriksaan laboratorium yang meliputi konsentrasi seng serum dantali pusat. Didapatkan rerata usia 27,63 ± 4,96 tahun dan sebagian besar subjekberada dalam kategori pendidikan tinggi dan pendapatan tinggi. Asupan sengmenunjukkan 98,4% subjek memiliki asupan seng kurang dari Angka KecukupanGizi (AKG) Indonesia. Nilai median konsentrasi seng serum maternal 53,70 (28.18-67,61) μg/dL dan 82,5% subyek tergolong dalam kategori adekuat. Nilai mediankonsentrasi seng serum tali pusat adalah sebesar 85,11(57.54 - 154,88) μg/dL, sedangkan 65,1% subjek tergolong dalam kategori tidakadekuat. Didapatkan rasio di antaranya 0,63 dengan korelasi tidak bermakna antarakonsentrasi seng serum maternal dengan tali pusat (r=0,04, p=0,78).

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ABSTRACTPregnancy is a period of rapid growth and cell differentiation, when both of themother and the fetus are very susceptible to alterations in dietary supply, especiallyof nutrients which are marginal under normal circumstances. Zinc is required forcellular division and differentiation, and is an essential nutrient for normalembryogenesis. Zinc deficiency has been associated with complications ofpregnancy and delivery, as well as growth retardation and congenital abnormalitiesin the fetus. It has been found that zinc levels keep decreasing during pregnancyfrom first trimester to third trimester. The aim of this cross sectional study was tofind the correlation between serum maternal and cordblood zinc level during thirdtrimester. Data collection was conducted during March 2015 to April 2015 on 10selected primary health service in East Jakarta. Subjects were obtained usingconsecutive sampling method. A total of 63 pregnant subjects had met the studycriteria. Data were collected through interviews including age, gestation age, parity,tobacco exposure, household income, maternal education, zinc intake, proteinintake, iron intake, and copper intake. Anthropometry measurements to assess thenutritional status and laboratory examination i.e blood levels of maternal andcordblood zinc. Mean age was 27.63 ± 4.96 years and majority of the subjects werehigh-educated and well-income. Intake of zinc showed 98.4% of the subjects wereless than recommended dietary allowances (RDA). Median of serum maternal zinclevels was 53.95 (27.97 ? 74.93) μg/dL, while 82.5% the of subjects werecategorized as adequate zinc levels. Median of serum cordblood zinc levels was84.92 (56.95 ? 155.86) μg/dL. No significant correlation was found between serummaternal and cordblood zinc (r=0.04, p=0.78) with the ratio between serummaternal and cordblood zinc was 0.63, Pregnancy is a period of rapid growth and cell differentiation, when both of themother and the fetus are very susceptible to alterations in dietary supply, especiallyof nutrients which are marginal under normal circumstances. Zinc is required forcellular division and differentiation, and is an essential nutrient for normalembryogenesis. Zinc deficiency has been associated with complications ofpregnancy and delivery, as well as growth retardation and congenital abnormalitiesin the fetus. It has been found that zinc levels keep decreasing during pregnancyfrom first trimester to third trimester. The aim of this cross sectional study was tofind the correlation between serum maternal and cordblood zinc level during thirdtrimester. Data collection was conducted during March 2015 to April 2015 on 10selected primary health service in East Jakarta. Subjects were obtained usingconsecutive sampling method. A total of 63 pregnant subjects had met the studycriteria. Data were collected through interviews including age, gestation age, parity,tobacco exposure, household income, maternal education, zinc intake, proteinintake, iron intake, and copper intake. Anthropometry measurements to assess thenutritional status and laboratory examination i.e blood levels of maternal andcordblood zinc. Mean age was 27.63 ± 4.96 years and majority of the subjects werehigh-educated and well-income. Intake of zinc showed 98.4% of the subjects wereless than recommended dietary allowances (RDA). Median of serum maternal zinclevels was 53.95 (27.97 – 74.93) μg/dL, while 82.5% the of subjects werecategorized as adequate zinc levels. Median of serum cordblood zinc levels was84.92 (56.95 – 155.86) μg/dL. No significant correlation was found between serummaternal and cordblood zinc (r=0.04, p=0.78) with the ratio between serummaternal and cordblood zinc was 0.63]"