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Hasil Pencarian

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Krista Ekaputri
Gambaran klinis dan fotogrametri parafinoma hidung perempuan Asia = Clinical features and basic photogrammetrics of paraffinoma in Asian nose.
"Praktik injeksi silikon atau parafin cair untuk memperbaiki penampilan pada hidung masih marak. Di lain pihak, rekonstruksi hidung parafinoma untuk mengembalikan ke bentuk normal sulit dicapai. Data objektif mengenai karakter distorsi pada hidung parafinoma dapat berguna untuk menjadi data awal sebagai pembanding untuk evaluasi hasil rekonstruksi hidung parafinoma. Studi ini memanfaatkan Mirror Stand MirS untuk mengambil foto wajah 30 subjek dengan parafinoma hidung. Ukuran fotogrametrik dikonversi menjadi ukuran morfometrik. Hasil pengukuran kemudian dianalisis untuk mendapatkan ciri distorsi dari hidung parafinoma. Ukuran meliputi intercanthal width, nasal root width, alar width, two tip defining points distance, nasofrontal angle, length of the nose radix to pronasion, nasofacial angle, nasion projection, pronasion projection, tip angle, nasolabial angle, columella length, the extend of extended columella danbase of the nose width. Hidung parafinoma memiliki ciri sebagai berikut; nasal root yang lebar (2.70 ± 0.30 cm); jarak two-tip defining pointsyang lebar (2.09 ± 0.22 cm), nasion projectionyang lebar (0.64 ± 0.36 cm), nasolabial angleyang sempit (78.81 ± 15.93), kolumela yang menggantung (0.47 ± 0.31 cm) dan porsi lobular dari tip hidung yang panjang (1.12 ± 0.20 cm).
The practice of injecting liquid silicone or paraffin at the nose for aesthetic purposes still continues today. On the other hand, normal apearance after reconstruction in nose paraffinoma is very difficult to achieve. The objective data regarding distortion characteristic in nose paraffinoma could be use as basic data to assess outcome of reconstruction in paraffinoma nose.Portable Mirror Stand MirS device is used to take standardized facial photographs of 30 patients with paraffinoma of the nose. Photogrammetrics measurements were then converted to morphometric measurement. The result was then analyzed to formulate the distortion characteristic of nose paraffinoma. Basic measurements included intercanthal width, nasal root width, alar width, two tip defining points distance, nasofrontal angle, length of the nose radix to pronasion, nasofacial angle, nasion projection, pronasion projection, tip angle, nasolabial angle, columella length, the extend of extended columella and base of the nose width. Paraffinoma nose has the following characteristics; wide nasal root base (2.70 ± 0.30 cm); wide two-tip defining point rsquo;s distance (2.09 ± 0.22 cm); wide nasion projection (0.64 ± 0.36 cm), acute nasolabial angle (78.81 ± 15.93 cm) hanging columella (0.47 ± 0.31 cm) and long lobular portion of the tip (1.12 ± 0.20 cm). "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Krista Ekaputri
Gambaran klinis dan fotogrametri parafinoma hidung perempuan Asia = Clinical features and basic photogrammetrics of paraffinoma in asian nose / Krista Ekaputri
"ABSTRAK
Praktik injeksi silikon atau parafin cair untuk memperbaiki penampilan pada hidung masih marak. Di lain pihak, rekonstruksi hidung parafinoma untuk mengembalikan ke bentuk normal sulit dicapai. Data objektif mengenai karakter distorsi pada hidung parafinoma dapat berguna untuk menjadi data awal sebagai pembanding untuk evaluasi hasil rekonstruksi hidung parafinoma. Studi ini memanfaatkan Mirror Stand MirS untuk mengambil foto wajah 30 subjek dengan parafinoma hidung. Ukuran fotogrametrik dikonversi menjadi ukuran morfometrik. Hasil pengukuran kemudian dianalisis untuk mendapatkan ciri distorsi dari hidung parafinoma. Ukuran meliputi intercanthal width, nasal root width,alar width,two tip defining points distance,nasofrontal angle,length of the nose radix to pronasion ,nasofacial angle,nasion projection,pronasion projection,tip angle,nasolabial angle,columella length,the extend of extended columella danbase of the nose width.Hidung parafinoma memiliki ciri sebagai berikut; nasal root yang lebar 2.70 0.30 cm ;jarak two-tip defining pointsyang lebar 2.09 0.22 cm , nasion projectionyang lebar 0.64 0.36 cm , nasolabial angleyang sempit 78.81 15.93 , kolumela yang menggantung 0.47 0.31 cm dan porsi lobular dari tip hidung yang panjang 1.12 0.20 cm .
ABSTRACT
The practice of injecting liquid silicone or paraffin at the nose for aesthetic purposes still continues today. On the other hand, normal apearance after reconstruction in nose paraffinoma is very difficult to achieve. The objective data regarding distortion characteristic in nose paraffinoma could be use as basic data to assess outcome of reconstruction in paraffinoma nose.Portable Mirror Stand MirS device is used to take standardized facial photographs of 30 patients with paraffinoma of the nose. Photogrammetrics measurements were then converted to morphometric measurement. The result was then analyzed to formulate the distortion characteristic of nose paraffinoma. Basic measurements included intercanthal width, nasal root width, alar width, two tip defining points distance, nasofrontal angle, length of the nose radix to pronasion , nasofacial angle, nasion projection, pronasion projection, tip angle, nasolabial angle, columella length, the extend of extended columella and base of the nose width. Paraffinoma nose has the following characteristics wide nasal root base 2.70 0.30 cm wide two tip defining point rsquo s distance 2.09 0.22 cm wide nasion projection 0.64 0.36 cm , acute nasolabial angle 78.81 15.93 hanging columella 0.47 0.31 cm and long lobular portion of the tip 1.12 0.20 cm . "
2018
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Puti Adla Runisa
Evaluation of sexual function in post penile reconstruction patients with split thickness skin graft due to siliconoma with IIEF-5 = Evaluasi fungsi seksual pada pasien pasca rekonstruksi silikonoma penis menggunakan tandur kulit dengan IIEF-5
"

atar Belakang: Silikonoma penis merupakan suatu proses inflamasi yang menyebabkan deformitas pada penis, yang disebabkan oleh penyuntikan substansi non-biologis pada penis, dan menyebabkan kerusakan yang hebat. Tata laksana berupa eksisi radikal kadang menjadi satu-satunya pilihan, dengan penutupan defek menggunakan tandur kulit. Namun, tandur kulit menyebabkan kontraktur sekunder dan terputusnya ujung saraf dari kulit, sehingga berpotensi menyebabkan disfungsi seksual. Studi ini dilakukan untuk mengevaluasi pasien tersebut dengan menggunakan IIEF-5.

Metode: Studi ini merupakan studi cross sectional retrograde yang melibatkan pasien silikonoma penis yang di rekonstruksi menggunakan tandur kulit di Rumah Sakit Hasan Sadikin dan Cipto Mangunkusumo dari januari 2015 ke juli 2019. Pasien yang bersedia mengikuti penelitian ini akan dievaluasi fungsi seksualnya menggunakan kuesioner IIEF-5.

Hasil: Terdapat total 36 pasien silikonoma penis yang direkonstruksi dengan tandur kulit, dan 19 pasien bersedia untuk ikut serta pada penelitian ini. Dari total pasien, 16 (84,2%) pasien memiliki fungsi seksual yang normal, 2 (10,5%) mengalami disfungsi ereksi ringan dan 1 (5,3) mengalami disfungsi ereksi ringan-sedang.

Kesimpulan: Pasien dengan silikonoma penis yang mendapatkan rekonstruksi dengan penutupan defek menggunakan tandur kulit memiliki fungsi seksual jangka panjang yang baik, sehingga dapat digunakan sebagai opsi penutupan defek.

Background: The necessity for penile augmentation has been present throughout history, using non-biological high viscosity substances resulting in detrimental damages, leading to siliconoma. Surgical management with radical excision with choices of split thickness skin graft as defect closure option for resurfacing. Nevertheless, the presence of secondary contracture and sensation diminution of the graft might interfere with sexual function. The aim of this study is to evaluate sexual function in penile siliconoma patient post skin graft reconstruction, using Simplified International Index of Erectile Function (IIEF-5).

Methods: This is a retrograde cross-sectional study involving penile siliconoma patients receiving reconstruction using split thickness skin graft at Hasan Sadikin and Cipto Mangunkusumo General Hospital from January 2015 to July 2019. All patients willing to enroll in this study were given the IIEF-5 questionnaire for sexual function evaluation.

Result: A total patient of 36 people was detected through medical record in both centers, and 19 were willing to be enrolled in this study. Among the patients, 16 (84.2%) had normal sexual function and 2(10.5%) Mild and 1(5.3%) had mild to moderate erectile disfunction.

Conclusion: Penile siliconoma patients receiving radical excision and resurfacing using skin graft has a good sexual function, and could be used as a resurfacing option in the treatment of penile siliconoma.

"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Siregar, Marsintauli Hasudungan
Gambaran klinis radiologis histopatologis dan faktor prognostik tumor otak pada anak = Clinical radiology histopathology features and prognostic factor of child brain tumor
"[ABSTRAK
Tumor otak (TO) merupakan penyebab kematian kedua dari
semua kanker yang terjadi pada anak. TO memiliki gambaran klinis, radiologis
dan histopatologis yang sangat bervariasi karena proses pengembangan sel-sel
jaringan otak masih berlanjut sampai usia 3 tahun. Data penelitian mengenai TO
pada anak masih sedikit.
Tujuan: Untuk mengetahui gambaran klinis, radiologis, histopatologis dan faktor
prognostik TO di Departemen Ilmu Kesehatan Anak FKUI/ RS. Dr.
Ciptomangunkusumo Jakarta periode tahun 2010 - 2015.
Metode Penelitian: Kohort retrospektif dilakukan pada semua anak dengan TO
primer yang berobat/dirawat di Departemen Ilmu Kesehahatan Anak FKUI/RS
Dr. Ciptomangunkusumo Jakarta.
Hasil: Didapatkan 88 pasien TO primer, terdiri dari 16 pasien berusia kurang dari
3 tahun dan 72 pasien berusia lebih dari 3 tahun, laki-laki 53% dan perempuan
47%. Anak usia kurang dari 3 tahun mengalami gejala sakit kepala (63%) dan
kejang (56%), berdasarkan radiologis letak TO yang terbanyak adalah di cerebral
ventrikel (25%) dan cerebellum (24%), berdasarkan histopatologis jenis TO yang
terbanyak adalah Astrositoma (31%) dan Medulloblastoma (25%). Anak usia
lebih dari 3 tahun mengalami gejala sakit kepala (81%) dan gangguan penglihatan
(65%), berdasarkan radiologis letak TO yang terbanyak adalah di cerebellum
(24%) dan suprasellar (10 %), berdasarkan histopatologis jenis TO yang
terbanyak adalah Medulloblastoma (21%), Astrositoma (18%) dan Glioma (17%).
Angka kehidupan TO adalah 37 %. Tidak didapatkan faktor prognostik TO yang
bermakna.
Kesimpulan: Gejala TO tersering adalah sakit kepala, berdasarkan radiologis
letak tumor terbanyak adalah di cerebellum serta berdasarkan histopatologis jenis
tumor terbanyak adalah Medulloblastoma dan Astrositoma. Tidak didapatkan
faktor prognostik TO pada anak.
ABSTRACT
Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.;Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor., Background: Primary brain tumors rank second as the most frequent neoplasm in
children. The lesions occurring in neonates or infants have been reported to differ
from those in older children in terms of their clinical presentation, radiology and
histopathology features.
Objective To clarify the clinical presentation, radiology, histopathology features.
and prognostic factor of primary brain tumors in Child Department
Ciptomangunkusumo Hospital Jakarta in 2010 - 2015.
Method: Retrospective cohort using medical records and neuroradiological dan
histopathological studies, we analyzed each patient?s clinical presentation, tumor
location, histopathological diagnosis and treatment then we compared between
under 3 years of age and more 3 years of age . The patients were followed until
their death or until the end of October 2015.
Result: 88 patient of primer brain tumor that consist of 16 patients with under 3
years of age and 72 patients with more 3 years of age. Boys are 53% and girls
are 47% . The most symptoms of children under 3 years of age is headache (63%)
and seizure (56%), based on radiology the most location tumor is cerebral
ventrikel (25%) and cerebellum (24%), based on histopathology the predominant
tumor is Astrositoma (31%) and Medulloblastoma (25%). The most symptoms
of children more 3 years of age is headache (81%) and visual difficulties (65%),
based on radiology the most tumor location is cerebellum (24%) and suprasellar
(10 %), based on histopathology the predominat tumor is Medulloblastoma
(21%), Astrositoma (18%) and Glioma (17%). The life expectancy rate is 37 %.
There is no prognostic factor of brain tumor.
Conclusion: The most symptom of brain tumor is headache, based on radiology
the most tumor location is cerebellum, and based on histopathology the
predominant tumor is Medulloblastoma and Astrositoma. There is no prognostic
factor of brain tumor.]"
2016
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Ayu Putri Laksmidewi
Gambaran Klinis dan Topografi Anatomi CT Sken Otak Pada Stro Iskemik = Clinical Features and Topographic Anatomy CT Brain Scenes in Ischemic Stroke
"Diagnosis strok sering ditegakkan berdasarkan pembuktian klinis dengan anamnesis dan pemeriksaan klinis neurologis saja. Akan tetapi gambaran klinis yang ditemukan tidaklah selalu sama, seringkali bervariasi sehingga diagnosa topis tidak selalu tepat. Diteliti hubungan antara gambaran klinis dengan topografi anatomi/ tipe infark pada CT-sken otak pad a penderita strok iskemik. Penelitian ini dilakukan secara prospektif, "cross sectional" dan bersifat deskriptif analitik. Populasi adalah penderita strok iskernik kejadian pertama berusia 40 tahun dan 65 tahun yang dirawat di ruang perawatan klas III RSUPN-CM Jakarta. Sejak bulan April sampai dengan Juli 1996, didapatkan 52 kasus strok iskemik kejadian pertama. Terdiri dari 34 laki-laki (65,3%) dan perempuan 18 (34,7%) dengan rasio laki : perempuan adalah 1,9 : 1 . Strok trombosis ditemukan terbanyak yaitu 93,9% sedangkan strok emboli 6,1 %. Dari 52 penderita yang diteliti, didapatkan basil CT-sken otak adalah 29 (59,2 %) berupa infark tentorial , 20 (40,8%) adalah infark lakunar, hanya satu kasus ditemukan berupa infark watershed dan dua lainnya dengan infark multipel. Pada pemeriksaan CT otak pertama, dua kasus tidak memperlihatkan adanya gambaran infark sehingga dilakukan pemeriksaan CT otak yang kedua yaitu antara hari ke 7 - 10 , didapatkan hasil berupa infark lakunar pada kedua kasus tersebut. Hemihipatesis ringan ditemukan pada 44,8% strok dengan tipe infark tentorial dan 70 % pada strok lakunar. Hemihipatesis berat hanya ditemukan pada strok dengan tipe infark tentorial. Hemihipestesi ditemukan 55,2% pada strok tipe tentorial dan 75 % pada strok tipe lakunar. Afasis hanya ditemukan pada strok tent
The diagnosis of stroke is often made based on clinical evidence with anamnesis and neurological clinical examination alone. However, the clinical picture found is not always the same, it often varies so that the diagnosis of topis is not always correct. The relationship between clinical features and anatomical topography/type of infarction on brain CT scans in ischemic stroke sufferers was studied. This research was conducted prospectively, "cross sectional" and is descriptive analytic in nature. The population was first-time iskernic stroke sufferers aged 40 years and 65 years who were treated in class III treatment rooms at RSUPN-CM Jakarta. From April to July 1996, there were 52 cases of first-occurrence ischemic stroke. Consisting of 34 men (65.3%) and 18 women (34.7%) with a male: female ratio of 1.9: 1. The highest number of thrombotic strokes was found, namely 93.9%, while embolic strokes were 6.1%. Of the 52 patients studied, brain CT scan results showed that 29 (59.2%) were tentorial infarctions, 20 (40.8%) were lacunar infarctions, only one case was found to be a watershed infarction and the other two were multiple infarctions. In the first brain CT examination, two cases did not show any signs of infarction so a second brain CT examination was carried out, namely between days 7 - 10, the results were lacunar infarcts in both cases. Mild hemihypathesis was found in 44.8% of tentorial strokes and 70% of lacunar strokes. Severe hemihypathesis is only found in strokes with tentorial infarction type. Hemihypesthesia was found in 55.2% of tentorial type strokes and 75% of lacunar type strokes. Aphasis is only found in tentorial strokes."
Depok: Fakultas Kedokteran Universitas Indonesia, 1996
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Deka Larasati
Hubungan Gambaran Klinis, Endoskopi, Histopatologi terhadap Ekspresi HER2 dan Kesintasan Dua Tahun pada Adenokarsinoma Gaster = Association between Clinical, Endoscopy, Histopathology Features with HER2 Expression and Two-Year Survival in Gastric Adenocarcinoma
"Latar Belakang: HER2 merupakan protoonkogen menjadi dasar pemberian terapi sel target pada adenokarsinoma gaster stadium lanjut. Penelitian hubungan antara gambaran klinis, endoskopi dan histopatologi dengan ekspresi HER2 masih menunjukkan hasil yang berbeda. Penelitian tentang HER2 sebagai prediktor kesintasan juga menunjukkan hasil yang berbeda. Penelitian ini bertujuan untuk mengetahui hubungan gambaran klinis, endoskopi, histopatologi dengan ekspresi HER2 dan hubungan antara ekspresi HER2 dengan kesintasan dua tahun.
Metode: Penelitian kohort retrospektif pada subyek adenokarsinoma gaster yang baru terdiagnosis, berusia ³ 18 tahun di 4 rumah sakit di Jakarta, berobat dari 2015-2019, memenuhi kriteria inklusi: memiliki rekam medis yang lengkap, hasil pemeriksaan gastroskopi, blok parafin hasil biopsi. Slide biopsi diwarnai dengan pewarnaan imunohistokimia HER2 dan diinterpretasi dengan kriteria ToGA. Analisis statistik deskriptif dan bivariat dengan menggunakan chi square/tes fisher untuk menilai hubungan antara gambaran klinis, endoskopi, dan histopatologi dengan ekspresi HER2. Analisis kesintasan, bivariat dan multivariat dengan Cox-regresi menentukan pengaruh ekspresi HER2 terhadap kesintasan dua tahun.
Hasil: Ekspresi HER2 positif ditemukan pada 12,3% subyek (15 dari 122 subyek). Ekspresi HER2 cenderung lebih tinggi pada metastasis ke hati, klasifikasi Borrman tipe I/II, diferensiasi baik/sedang, tipe intestinal berdasarkan Klasifikasi Lauren memiliki dengan proporsi masing-masing: 17.6% RR(IK95%)=1.726 (0.665-4.480), 16.1% RR(IK95%)=1,768(0,670-4,662), 14.3% RR(IK95%)=1,304(0,505-3,363), 13.9% RR(IK95%)=1,389(0,505-3,817).Ekspresi HER2 positif tidak berhubungan dengan kesintasan dua tahun, HR (IK95%)=1,12(0,609-2,058).
Simpulan: Matastasis hati, klasifikasi Borrman, letak tumor, diferensiasi tumor dan klasifikasi Lauren tidak berhubungan bermakna secara statistik terhadap ekspresi HER2. Ekspresi HER2 positif tidak berhubungan dengan kesintasan dua tahun pada adenokarsinoma gaster.
Background: HER2 is a proto-oncogene which important for administering of target cell therapy in advanced gastric adenocarcinoma. Research on clinical, endoscopic, and histopathological features shown conflicting in association with HER2 expression. Studies on HER2 as a predictor of survival still show different results. This study aims to determine association of the clinical, endoscopic, and histopathological features with HER2 expression and association of HER2 expression with 2-year survival.
Methods: A retrospective cohort study on newly diagnosed gastric adenocarcinoma subjects, aged 18 years old at 4 hospitals in Jakarta, receiving treatment from 2015-2019, meeting the inclusion criteria: having complete medical record, results of gastroscopy examination, and paraffin block tumor biopsy results. The biopsy slides were stained with HER2 immunohistochemical staining and interpreted according to the ToGA criteria. Descriptive and bivariate analysis by using chi-square or fisher's test assessed the relationship between clinical, endoscopic, and histopathological features with HER2 expression. Survival, bivariate and multivariate analysis with cox regression method were used to determine the effect of HER2 expression on 2-year survival.
Results: Positive HER2 expression was found in 12.3% of subjects (15 of 122 subjects). HER2 expression tends to be higher in metastases to the liver, Borrman classification type I/II, good/moderate differentiation, intestinal type based on Lauren's classification has the respective proportions:17.6% RR (95%CI)=1.726 (0.665-4.480), 16.1% RR (95%CI)=1,768 (0,670-4,662), 14.3% RR (95%CI)=1,304 (0,505-3,363), 13.9% RR (95%CI)=1,389 (0,505-3,817). Positive HER2 expression was not associated with 2-year survival with HR (95%CI) =1.12 (0.609-2.058)."
Depok: Fakultas Kedokteran Gigi Universitas Indonesia, 2022
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ABC telinga, hidung, dan tenggorok = ABC of ear, nose, and throat
"This book follows a symptomatic approach for evaluation and prioritisation of common presentations, and provides guidance on primary care assessment and management, and on when and why to refer for a specialist opinion. Fully revised to reflect the current practice of oto-rhino-laryngology and head and neck surgery, new chapters address the increasing specialization and improved understanding of the likely causes and specialist treatment for symptoms such as tinnitus, nasal discharge, nasal obstruction, facial plastic surgery, head and neck trauma and foreign bodies, and non-specialist assessment and examination. There is new content on rhinoplasty, pinnaplasty, non-melanoma skin tumours, thyroid disease and head and neck cancer, with many new full colour illustrations and algorithms throughout.
ABC of Ear, Nose and Throat is a long established best-selling guide to the management of common conditions of the Ears, Nose and Throat. It follows a symptomatic approach for evaluation and prioritisation of common presentations, and provides guidance on primary care assessment and management, and on when and why to refer for a specialist opinion. Fully revised to reflect the current practice of oto-rhino-laryngology and head and neck surgery, new chapters address the increasing specialization and improved understanding of the likely causes and specialist treatment for symptoms such as tinn."
Jakarta: EGC, 2012
617.51 ABC
Buku Teks SO  Universitas Indonesia Library
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Hernawan
Tingkat sensitivitas dan spesifisitas kombinasi gambaran klinis dan Ultrasonografi untuk diagnosis Sindroma Terowongan Karpal di Rumah Sakit Cipto Mangunkusumo = The level of sensitivity and specificity of the combination of clinical features and Ultrasonography for the diagnosis of Carpal Tunnel Syndrome in Cipto Mangunkusumo Hospital / Hernawan
"Latar Belakang. Perkembangan teknologi dan meningkatnya peran penggunaan tangan di bidang industri, rumah tangga dan perkantoran akan meningkatkan angka kejadian STK. Hal ini akan memiliki dampak negatif di bidang medis, sosial dan ekonomi. Pemeriksaan Ultrasonografi (USG) berguna sebagai penunjang dalam mendiagnosis STK. Kemajuan dalam kualitas dan portabilitas USG telah menempatkan USG sebagai alat pilihan dalam penelitian dan penerapan klinis di bidang neurologi. USG mudah dijumpai di pelayanan kesehatan, memiliki biaya yang murah, waktu pemeriksaan yang singkat dan tidak invasif, serta memiliki sensitivitas dan spesifisitas yang cukup baik dalam mendiagnosis STK.
Metode. Desain penelitian berupa studi potong lintang. Subyek penelitian adalah pasien Poliklinik Neurologi RSCM yang memenuhi kriteria inklusi dan eksklusi. Subyek diperoleh secara konsekutif. Pada subyek dilakukan wawancara, pengisian kuesioner, pemeriksan fisik, elektroneurografi dan ultrasonografi di Poliklinik Neurologi RSCM. Dilakukan analisis data menggunakan perangkat SPSS 17.0.
Hasil. Diperoleh 58 subyek tangan yang masuk kriteria inklusi. Sensitivitas dan spesifisitas kombinasi gambaran klinis dan USG adalah 86,04% dan 73,33%. Sedangkan akurasi kombinasi gambaran klinis dan USG sebesar 82,75%. Terdapat kesesuaian antara pemeriksaan kombinasi klinis dan USG dengan kombinasi klinis dan elektroneurografi dalam mendeteksi STK (kappa = 0,70).
Kesimpulan. Nilai sensitivitas kombinasi gambaran klinis dan USG sama dengan elektroneurografi. Sedangkan spesifisitas kombinasi gambaran klinis dan USG lebih rendah daripada elektroneurografi. Kombinasi gambaran klinis dan USG dapat digunakan sebagai alternatif pemeriksan dalam mendiagnosis STK.
Background. Technological development and the increased use of hands in the fields of industrial, household and office space will increase the prevalence of Carpal Tunnel Syndrome (CTS). This will have a negative impact on medical science, social and economic. Ultrasonography (USG) is useful to support diagnosis of CTS. Progress in the quality and portability of ultrasound has placed ultrasound as a chosen instrument in research and clinical application in the field of neurology. USG is easily found at the health centers, has a lower cost, a short examination time and not invasive, as well as having superior specificity and sensitivity is good enough in diagnosing CTS.
Method. A cross-sectional sectional study was conducted. The research subject were patients of the Neurology Clinic of RSCM Hospital who meet all of the inclusion and exclusion criteria.
Result. Fifthy eight hands were included in this study. The sensitivity and specificity of the combination of clinical features and ultrasonography were 86.04% and 73.33%. While, the accuracy of the combination of clinical features and ultrasonography was 82.75%. There is a conformity between the combination of clinical features and ultrasound with a combination of clinical picture and electroneurography in diagnosing CTS (kappa = 0.70).
Conclusion. The combination of clinical features and ultrasonography has similar sensitivity with electroneurography. Meanwhile, the specificity of the combination of clinical features and ultrasonography is inferior to electroneurography. Thus, the combination of clinical features and ultrasonography can be used as an alternative to electroneurography in diagnosing CTS."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2012
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Asian journal of English languange teaching
Hong Kong: The Chinese University Press, 2001
430 ASJOELT
Majalah, Jurnal, Buletin  Universitas Indonesia Library
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Rahmat Cahyanur
Gambaran klinis dan proporsi hipotiroidisme sekunder pada pasien adenoma hipofisis di Rumah Sakit Cipto Mangunkusumo = Clinical features and proportion of secondary hypothyroidism of pituitary adenoma patient in cipto mangunkusumo general hospital / Rahmat Cahyanur
"Latar Belakang : Adenoma hipofisis merupakan tumor intrakranial yang berasal dari jaringan hipofisis anterior. Manifestasi klinis yang ditimbulkan terkait dengan pendesakan massa dan gangguan sekresi hormon. Salah satu gangguan hormonal yang ditimbulkan adalah hipotiroidisme sekunder. Hipotiroidisme sekunder terkait dengan penurunan kualitas hidup serta peningkatan risiko kardiovaskular.
Tujuan : Penelitian ini bertujuan untuk mengetahui proporsi hipotiroidisme sekunder dan gambaran klinis pasien adenoma hipofisis.
Metode : Penelitian ini adalah studi potong lintang. Data diambil dari rekam medis pasien di Rumah Sakit Cipto Mangunkusumo (RSCM) Jakarta dalam kurun waktu tahun 2007-2012. Data demografis pasien (usia, jenis kelamin), karakteristik klinis, jenis adenoma, data radiologis, serta hasil pemeriksaan hormon (T4 bebas dan TSH) dievaluasi pada peneltian ini.
Hasil : Selama kurun waktu 2007-2012 terdapat 63 pasien adenoma hipofisis di RSCM. Sebanyak 45 pasien memiliki data yang lengkap dan diikutsertakan sebagai subyek pada penelitian ini. Sebagian besar subyek adalah wanita (62,2%). Keluhan utama subyek adalah gangguan penglihatan (55,6%). Gejala atau tanda yang sering ditemukan adalah sakit kepala (86,7%), gangguan penglihatan (77,8%). Pada subyek wanita manifestasi yang pertama kali muncul adalah gangguan penglihatan dan gangguan fungsi seksual (39,3% dan 32,1%). Usia gejala pertama kali muncul lebih muda pada kelompok adenoma fungsional dibandingkan non fungsional (32,9 vs. 40,6). Hampir seluruh kasus yang ditemukan adalah makroadenoma (97,8%). Proporsi subyek yang mengalami hipotiroidisme sekunder adalah 40%. Subyek dengan hipotiroidisme sekunder lebih banyak mengeluhkan gangguan penglihatan dan gangguan ereksi.
Simpulan : Gangguan penglihatan adalah keluhan utama yang sering ditemukan. Pada subyek wanita, keluhan gangguan fungsi seksual bersama dengan gangguan penglihatan adalah manifestasi yang pertama kali muncul. Proporsi hipotiroidisme sekunder pada penelitian ini adalah 40,0 %. Subyek dengan hipotiroidisme sekunder lebih banyak mengeluhkan gangguan penglihatan, gangguan ereksi.
Background : Pituitary adenoma is intracranial neoplasm that arise from anterior pituitary tissue. Clinical manifestations are caused by mass effect and hormonal secretion disorder. One of the hormonal disorder is secondary hypothyroidism. Secondary hypothyroidism is related with increased cardiovascular morbidity and decreased quality of life.
Objectives: This study described the proportion of secondary hypothyroidism and and clinical features of pituitary adenoma patients.
Methods: This study was a cross sectional study. Data were collected from medical record in Cipto Mangunkusumo Hospital, from 2007 to 2012. Demographic data (age, gender), clinical characteristic, radiological result, adenoma type, and hormonal evaluation (free T4 and TSH) were evaluated.
Result : During 2007-2012 there were 63 patients with pituitary adenoma in Cipto Mangunkusumo Hospital.There were 43 patientswho fulfilled the study criteria. Majority of patients were female (62,2%). Visual disturbance was the most common presenting symptom (55,6%). Headache and visual disturbance were symptoms that commonly found, respectively (86,7% and 77,8%). Female subjects suffered visual disturbance and sexual dysfunction as their first occured symptoms, 39,3% and 32,1% respectively. Age at first symptom was younger in the subjects with functional adenoma compared non functional (32,9 vs. 40,6). Almost all cases were macroadenoma (97,8%). Secondary Hypothyroidism proportionin this study was 40 %. Subjects with secondary hypothyroidism had higher frequencies of visual distrubance and erectile dysfunction.
Summary : Visual disturbance is most common presenting symptom. Female subjects tend to had visual disturbance and sexual dysfunction as their first symptom. Secondary Hypothyroidism proportion in this study was 40 %. Subjects with secondary hypothyroidism had larger tumor diameter. Visual disturbance and erectile dysfunction commonly found in subjects with secondary hypothyroidism."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2013
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