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"ABSTRAKWe produced monoclonal antibody NG1 that strongly binds growing axons in the developing nervous system of mice. This antibody intensely labeled the growth cone of cultured neurons. Although these immunostaining patterns suggested the association of growing axons with the antigen recognized by this antibody, the antigen was identified as Nogo protein, an axonal repulsive factor isolated from the myelin. On the basis of this unexpected finding, we discuss the possible functions of Nogo in the developing nervous system."

"This book include 25 chapters contributed by more than 40 distinguished entomologists and introduces the latest progress in entomology, from molecular biology, insect-plant interactions and insecticide toxicology, to emerging technologies in pest management. "

"Scientists tend to take the thought processes that drive their research for granted, often learning them indirectly by observing first their supervisors and then their colleagues. This book emphasises the advantages of being explicit about these thought processes and aims to help those undertaking ecological research to develop a critical attitude to approaching a scientific problem and constructing a procedure for assessment. The outcome is a text which provides a framework for understanding methodological issues and which assists with the effective definition and planning of research. As such it represents a unique resource for anyone embarking on their research career. It also provides a valuable source of information for those more experienced researchers who are seeking to strengthen the methodology underlying their studies or who have an interest in the analysis of research methods in ecology."

"This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development."

"The book presents the first comprehensive molecular theory of the living cell ever published since the cell doctrine was formulated in 1838-1839. It introduces into cell biology over thirty key concepts, principles and laws imported from physics, chemistry, computer science, linguistics, semiotics and philosophy. The author formulates physically, chemically and enzymologically realistic molecular mechanisms to account for basic living processes such as ligand-receptor interactions, enzymic catalysis, force-generating mechanisms in molecular motors, chromatin remodelling, and signal transduction. Possible solutions to basic and practical problems facing contemporary biology and biomedical sciences have been suggested, including pharmacotherapeutics and personalized medicine. "

"This volume brings together contributions from experts in the field of Pasteurella research. Its covers areas such as comparative genomics, pathogenic mechanisms, bacterial proteomics, as well as a detailed description and analysis of PMT and its interaction with host tissues, cells, immune system, and signalling pathways."

"This book discusses, mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses, the role of autophagy and mitophagy, the relationship of apoptosis to aging processe, the role of asymmetric segregation of damage in replicative aging, the role of replication stress, and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined."

"Summary: The definitive "bible" for the field of biomedical engineering, this collection of volumes is a major reference for all practicing biomedical engineers and students. Now in its fourth edition, this work presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personalized medicine, and stem cell engineering. Also included is a historical overview as well as a special section on medical ethics. This set provides complete coverage of biomedical engineering fundamentals, medical devices and systems, computer applications in medicine, and molecular engineering"

"This book includes chapters on classic and modern aspects of centrosome research. Centrosome research focused on primary cilia and their dysfunctions that are implicated in numerous diseases and include cell and molecular details that are important for the specific subtopics. "

"This book will provide a detailed review of existing knowledge on the functional characterization of biological networks. In 15 chapters authored by an international group of prolific systems biology and bioinformatics researchers, it will organize, conceptualize, and summarize the existing core of research results and computational methods on understanding biological function from a network perspective."