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"In February 2016, the Minister of Health decided to increase the use of research findings in improving the quality of the national health policy and planning. The Ministry of Health has instructed the National Institute of Health Research and Development or NIHRD to play a stronger role of monitoring and evaluating all health programs, because their opinion and research findings should be the basis for changes in national health policies and planning. Compared to the past, the Ministry of Health has increased the research budget for evidence-based research tremendously. However, there is a gap between the information needs of program and policy makers and the information offered by researchers. A close dialogue is needed between the users (program managers, policy makers and planners) and the suppliers (researchers and evaluators) to ensure that the evidence-based supplied by research is useful for programs, planning and health policy."

"Due to particular conditions, sometimes actual height can not be measured. Thus, this study was conducted to develop height prediction model of adolescent from knee height and ulna length. This cross sectional study involved 205 students of SMPN 7 Depok and SMAN 6 Depok. Subjects’s identity was recorded using questionairre, while stature height, knee height, and ulna length was measured directly. Prediction models was developed using multiple regression. Height prediction model from knee height has the highest R2 and the lowest MAE with equation Height (cm) = 38,422 - 1,878 Sex + 1,453 Age (year) + 2,071 knee height (cm).

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Tinggi badan aktual terkadang tidak dapat diukur karena beberapa kondisi tertentu. Oleh karena itu, penelitian ini bertujuan mengembangkan model prediksi tinggi badan pada remaja berdasarkan tinggi lutut dan panjang ulna. Penelitian pontong lintang ini melibatkan 205 murid SMPN 7 Depok dan SMAN 6 Depok. Data identitas subjek diperoleh melalui pengisian kuesioner, sedangkan tinggi badan, tingi lutut, dan panjang ulna diukur langsung. Model prediksi dikembangkan menggunakan regresi ganda. Model prediksi tinggi badan dari tinggi lutut memiliki R2 terbesar dan MAE terkecil dengan persamaan Tinggi Badan (cm) = 38,422 - 1,878 Jenis Kelamin + 1,453 Umur (thn) + 2,071 Tinggi Lutut (cm)."

"Latar belakang: luka bakar berat dapat disertai dengan trauma inhalasi, yang akan memicu respons lokal dan sistemik, sehingga menyebabkan berbagai komplikasi, termasuk systemic inflammatory response syndrome (SIRS) dan sepsis. Berbagai kondisi ini menyebabkan hipermetabolime dan hiperkatabolisme, yang membutuhkan tatalaksana nutrisi adekuat untuk membantu proses penyembuhan pasien. Berbagai kelompok ahli telah memberikan rekomendasi tatalaksana nutrisi pada luka bakar berat dan sakit kritis. Namun, akibat keterbatasan sarana dan prasarana, tidak semua rekomendasi dapat dilaksanakan, sehingga tatalaksana nutrisi diberikan secara optimal. Metode: serial kasus ini terdiri atas empat pasien luka bakar berat, yang disebabkan oleh api, dan disertai trauma inhalasi, yang menyebabkan berbagai komplikasi, sepsis, multiple organ dysfunction syndrome (MODS) dan multiple organ failure (MOF). Tatalaksana nutrisi diberikan secara bertahap sesuai dengan keadaan pasien. Pemberian nutrisi diawali dengan nutrisi enteral dini (NED) dalam waktu 2448 jam setelah luka bakar, sebesar 10 kkal/kg BB, menggunakan drip intermiten. Selanjutnya, nutrisi diberikan sebesar 2025 kkal/kg BB pada fase akut dan 2530 kkal/kg BB/hari pada fase anabolik. Setelah pasien keluar dari intensive care unit (ICU), target kebutuhan energi menggunakan persamaan Xie, dengan protein 1,52,0 g/kg BB/hari, lemak 2530%, dan karbohidrat (KH) 5565%. Mikronutrien diberikan berupa multivitamin antioksidan, vitamin B, asam folat, dan vitamin D. Pasien dalam serial kasus ini juga mendapatkan nutrisi spesifik glutamin sebesar 0,3 g/kg BB/hari, selama 510 hari. Hasil: tiga pasien mengalami perbaikan klinis, kapasitas fungsional, dan laboratorium. Pasien selamat dan dipulangkan untuk rawat jalan. Masa rawat pasien yang selamat berturut-turut 33 hari, 70 hari, dan 43 hari. Seorang pasien mengalami perburukan dan MOF, hingga meninggal dunia setelah dirawat selama 23 hari di ICU. Kesimpulan: tatalaksana nutrisi optimal dapat menunjang penyembuhan luka serta menurunkan angka morbiditas dan mortalitas pasien luka bakar berat dengan trauma inhalasi dan sepsis.

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;Background: severe burn trauma combined with inhalation injury initiates local and systemic response, resulting in various complications such as systemic inflammatory response syndrome (SIRS) and sepsis. These conditions stimulate hypercatabolic process, leading to the increase of nutrition requirement. Adequate nutritional support is necessary in order to control both inflammatory and metabolic response, and also to improve healing process. To date, nutritional recommendations specific for severe burn trauma and critical illness have been established. However, many problems including patient?s condition and lack of resources exist, so optimal nutritional support that fits our settings was delivered. Method: this serial case focused on four severely burned patients caused by flame. Subjects with inhalation trauma and complications such as sepsis, multiple organ dysfunction syndrome (MODS), and multiple organ failure (MOF) were included in this study. Nutritional support was delivered according to clinical conditions, patient?s tolerance, and laboratory findings. Early enteral nutrition was initiated within 2448 hours post burns, starting from 10 kcal/kg BW/day with intermittent gravity drip method. Nutrition was gradually increased in order to reach the target of energy for critically ill patients, which is 2025 kcal/kg BW/day in acute phase or 2530 kcal/kg BW/day in anabolic recovery phase. Xie Equation was used to calculate target of total energy for burned patient. Protein requirement was 1.52.0 g/kg BW/day. Lipid and carbohydrate given were 2530% and 5565% from calorie intake, respectively. Micronutrient supplementation including antioxidants, vitamin B, folic acid, and vitamin D was also provided. Glutamin as specific nutrient was delivered by 0.3 g/kg BW/day in 510 days. Results: improvement of clinical condition, functional capacity, and laboratory parameters was observed in three patients, who could be discharged from hospital and asked to come back for outpatient care. Their lengths of stay were 33 days, 70 days, and 43 days, respectively. However, one patient experienced worsening of condition and died after 22 days of care in Intensive Care Unit (ICU). Conclusions: optimal nutritional support for severely burned patients with inhalation trauma and sepsis is necessary in order to improve healing process, as well as decrease morbidity and mortality."

"ABSTRAKBerkembangnya tekonologi membuat munculnya banyak mobile application salah satunya aplikasi kesehatan XYZ. Aplikasi XYZ memediasi konsultasi kesehatan dan pembelian obat sehingga dapat dilakukan secara online. Penelitian ini membahas tentang intension to use aplikasi kesehatan XYZ dengan mengadopsi Integreated Theori Trust-TAM. Penelitian ini menggunakan metode kuantitatif dengan objek penelitian Komunitas X. Dari hasil penelitian terbukti bahwa aplikasi XYZ mampu untuk membentuk kepercayaan antara dokter dan pasien tanpa harus bertemu tatap muka dalam menjalinkomunikasi digital dan terdapat hubungan pengaruh antara perceived usefulness, perceived ease of use dan trust terhadap intention to use aplikasi kesehatan berbasis online XYZ. Trust menjadi faktor utama dalam penentuan intention to use.

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ABSTRACTThe development of technology makes the emergence of many mobile applications, one of which is XYZ health applications. The XYZ application mediates health consultations and drugs purchases so that it can be done online. This study discusses the intention to use XYZ health applications by adopting an Integrated Theory Trust-TAM. This study uses quantitative methods with the object of research is Community X. From the results of the research, it is proven that XYZ application is able to form trust between doctors and patients without having to meet face to face in establishing digital communication and there is a relationship of influence between Perceived Usefulness, Perceived Ease of Use and Trust has an influence on intention to use XYZ online based health applications. Trust is a major factor in determining intention to use."

"ABSTRACTThe development of male hormonal contraception is based on a decrease in sperm concentration without affectinglibido and sexual potency. The combination of depot medroxy progesterone acetate (DMPA) + extract of Javanese longpepper (JLP) with dosages of 0.94 mg and 1.88 mg decreases the concentration of spermatozoa. However, it remainsunknown whether the combination influences body weight, hematology, and blood biochemistry. Therefore, it isnecessary to investigate the effect of DMPA + JLP extracts on the body weight, hematology, and blood biochemistry ofmale rats (RattusnorvegicusL.) using Sprague-Dawley strains. The research uses a completely randomized design (CRD); one group control and two treatment groups. In the first group, the castrated rats were given oral administration extracts of JLP (CJ) with doses of 0, 0.94, 1.88, 2.82, and 3.76 mg. In the second group, the rats were injected with 1.25mg DMPA and given an oral administration extract of JLP. Injection was given in week-0 and 12. Administration was conducted every day from week 7-18. Analysis of the normality and homogeneity of data is done before the ANOVA test. Data that is abnormal and not homogeneous are tested with non-parametric statistical Kruskal-Wallis. This studyshows that the combination of minimal doses of DMPA and administration variousdoses of extracts of JLP does notaffect body weight and hematology (erythrocyte, hemoglobin, hematocrite), and the blood biochemistry of rats, such asthe values of SGPT, SGOT, HDL, and triglycerides (p< 0.05), but rather the total cholesterol and LDL (p< 0.05). Furthermore, it is concluded that the combination of the minimal dosage of DMPA and weaned various dosages of JLPextracts affect the total value and LDL cholesterol but do not influence body weight, nor hematology and blood biochemistry. Such combinations can be drawn on for asafe male contraceptive model t by taking into account the value of the total cholesterol and LDL during its use."