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Freddy Julianto
"Fisik yang tidak aktif menempati peringkat keempat dalam daftar faktor risiko kematian. Bukti ilmiah semakin banyak mendukung bahwa dengan menjadikan latihan fisik sebagai bagian dari gaya hidup, dapat menurunkan risiko terjadinya berbagai penyakit. Namun, kelelahan otot dan nyeri otot juga banyak dirasakan oleh orang tidak terlatih yang baru memulai latihan. Penumpukan asam laktat di dalam otot sering dihubungkan dengan terjadinya kelelahan otot dan nyeri otot ini, yang akan memengaruhi kenyamanan melakukan latihan fisik. Saat ini, belum ada obat – obatan ataupun intervensi yang direkomendasikan secara resmi untuk menunda munculnya kelelahan otot atau nyeri otot. Penelitian ini menilai pengaruh akupunktur manual terhadap kenyamanan melakukan latihan fisik yang dievaluasi dengan menilai rerata kadar asam laktat, denyut nadi, tekanan darah sistolik dan diastolik, skala Borg untuk menilai tingkat kelelahan, serta Visual Analogue Scale (VAS) untuk menilai nyeri otot. Dua puluh enam pasien dibagi secara acak menjadi dua, kelompok akupunktur manual (n=13) dan akupunktur sham (n=13). Kedua kelompok menerima seri akupunktur yang sama, sebanyak 12 sesi dengan jarak 1 – 3 hari. Kedua kelompok juga melakukan latihan fisik yang sama, yaitu treadmill dengan intensitas sedang selama sepuluh menit, sebelum dan setelah seri terapi akupunktur. Penilaian rerata kadar asam laktat, denyut nadi, tekanan darah, skala Borg, dan VAS dilakukan dua kali, yaitu setelah latihan fisik sebelum memulai terapi pertama dan setelah latihan fisik setelah terapi terakhir. Hasil menunjukkan terdapat perbedaan bermakna pada rerata kadar asam laktat, denyut nadi, tekanan darah sistolik, tekanan darah diastolik, skala Borg, dan VAS pada kelompok akupunktur manual dibandingkan akupunktur sham. Rerata kadar asam laktat setelah terapi akupunktur 12 kali (p = 0,041). Rerata denyut nadi setelah terapi akupunktur 12 kali (p = 0,042). Rerata tekanan darah sistolik setelah terapi akupunktur 12 kali  (p = 0,024). Rerata tekanan darah diastolik setelah terapi akupunktur 12 kali (p = 0,035). Skala Borg setelah terapi akupunktur 12 kali (p = 0,043). VAS setelah terapi akupunktur 12 kali (p = 0,049). Penemuan ini menunjukkan bahwa terapi akupunktur manual memberikan pengaruh yang lebih baik terhadap kenyamanan melakukan latihan fisik.

Physical inactivity ranks fourth in the list of risk factors for death. Scientific evidence increasingly supports that by making physical exercise a part of lifestyle, it can reduce the risk of various diseases. However, muscle fatigue and muscle aches are also felt by many untrained people who are just starting training. The buildup of lactic acid in the muscles is often associated with the occurrence of muscle fatigue and muscle pain, which will affect the comfort of doing physical exercise. At present, there are no drugs or officially recommended interventions to delay the appearance of muscle fatigue or muscle aches. This study assessed the effect of manual acupuncture on the comfort of physical exercise which was evaluated by assessing the mean levels of lactic acid, pulse, systolic and diastolic blood pressure, the Borg scale to assess the level of fatigue, and the Visual Analogue Scale (VAS) to assess muscle pain. Twenty-six patients were randomly divided into two groups, manual acupuncture (n = 13) and sham acupuncture (n = 13). Both groups received the same series of acupuncture, with 12 sessions spaced 1-3 days. Both groups also did the same physical exercise, which was a treadmill with moderate intensity for ten minutes, before and after the acupuncture therapy series. The average assessment of lactic acid levels, pulse rate, blood pressure, the Borg scale, and VAS was carried out twice, namely after physical exercise before starting the first therapy and after physical exercise after the last therapy. The results showed that there were significant differences in the average levels of lactic acid, pulse, systolic blood pressure, diastolic blood pressure, Borg scale, and VAS in the manual acupuncture group compared to sham acupuncture. Average lactic acid levels after acupuncture therapy 12 times (p = 0.041). Mean pulse rate after acupuncture therapy 12 times (p = 0.042). The mean systolic blood pressure after acupuncture therapy was 12 times (p = 0.024). Average diastolic blood pressure after acupuncture therapy 12 times (p = 0.035). Borg scale after acupuncture therapy 12 times (p = 0.043). VAS after acupuncture therapy 12 times (p = 0.049). These findings indicate that manual acupuncture therapy has a better effect on the comfort of physical exercise."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
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UI - Tugas Akhir  Universitas Indonesia Library
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Andy Ishak
"Luka bakar didefinisikan sebagai kerusakan jaringan yang terjadi akibat aksi panas baik secara langsung maupun tidak langsung. Meskipun telah banyak kemajuan yang dibuat dalam terapi luka bakar, namun penyembuhan luka yang lambat masih menjadi tantangan dalam perawatan luka bakar. Akupunktur manual dapat mempercepat penyembuhan luka bakar melalui efek anti-inflamasi, meningkatkan re-epitelisasi dan angiogenesis. Sedangkan laser akupunktur merupakan terapi yang menggunakan laser enersi rendah untuk merangsang titik akupunktur. Penelitian ini menilai pengaruh akupunktur manual dan laser akupunktur terhadap kecepatan penyembuhan luka bakar yang diamati secara makroskopik dan mikroskopik. Tiga puluh enam tikus Wistar jantan dibagi secara acak kedalam kelompok kontrol (n=12), kelompok akupunktur manual (n=12), dan kelompok laser akupunktur (n=12). Setelah dilakukan induksi luka bakar, pengukuran luka dan perlakuan diberikan setiap dua hari sekali selama 14 hari. Separuh jumlah dari setiap kelompok diterminasi pada hari ke-7 dan separuh sisanya diterminasi pada hari ke-14 untuk dilakukan pengamatan mikroskopik. Pada pengukuran penutupan luas luka hari ke-14, didapatkan perbedaan bermakna (p=0,009) antara kelompok akupunktur manual (66,96 ± 9,17) dibandingkan kelompok kontrol (49,93 ± 9,15), dan perbedaan yang bermakna (p=0,009) antara kelompok laser akupunktur (72,48 ± 14,62) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,451) antara kelompok akupunktur manual dan laser akupunktur. Pada penilaian skoring mikroskopik hari ke-14 didapatkan perbedaan yang bermakna (p<0,001) antara kelompok akupunktur manual (16,17 ± 1,17) dibandingkan kelompok kontrol (10,33 ± 1,21), dan perbedaan yang bermakna (p=0,004) antara kelompok laser akupunktur (17,83 ± 1,47) dibandingkan kelompok kontrol. Namun tidak didapatkan perbedaan bermakna (p=0,058) antara kelompok akupunktur manual dan laser akupunktur. Hasil penelitian menunjukkan bahwa baik terapi akupunktur manual ataupun laser akupunktur dapat digunakan sebagai terapi tambahan untuk mempercepat penyembuhan luka bakar.

Burns are defined as tissue damage that occurs as a result of the direct or indirect action of heat. Although many advanced treatments have been made in burn therapy, slow wound healing remains a challenge in burn treatment. Acupuncture can accelerate burn healing through its anti-inflammatory effect, increasing re-epithelialization and angiogenesis. While laser acupuncture is a therapy that uses low energy lasers to stimulate acupuncture points. This study assessed the effect of manual acupuncture and laser acupuncture on the speed of wound healing which were observed macroscopically and microscopically. Thirty-six male Wistar rats were randomly divided into control group (n=12), acupuncture group (n=12), and laser acupuncture group (n=12). After burn induction, wound measurements and treatments were given every two days for 14 days. Half of the numbers from each group were terminated on the 7th day and the remaining half were terminated on the 14th day for microscopic observation. On the 14th day of measurement of wound closure, there was a significant difference (p=0.009) between the acupuncture group (66.96 ± 9.17) compared to the control group (49.93 ± 9.15), and a significant difference (p =0.009) between laser acupuncture group (72.48 ± 14.62) compared to control group. However, there was no significant difference (p=0.451) between acupuncture and laser acupuncture groups. On the 14th day of microscopic scoring, there was a significant difference (p<0.001) between the acupuncture group (16.17 ± 1.17) compared to the control group (10.33 ± 1.21), and a significant difference (p = 0.004) between the laser acupuncture group (17.83 ± 1.47) versus the control group. However, there was no significant difference (p=0.058) between acupuncture and laser acupuncture groups. The results showed that either acupuncture therapy or laser acupuncture could be used as an adjunct therapy to accelerate burn healing."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Tugas Akhir  Universitas Indonesia Library
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Ferry Aditya Phan
"[ABSTRAK
Uremik pruritus masih menjadi masalah dan mengurangi kualitas hidup pada pasien hemodialisis, meskipun telah banyak kemajuan dalam teknik dialisis, serta terapi yang ada belum memberikan hasil yang maksimal. Terapi akupunktur dapat dikembangkan sebagai terapi pendamping pada terapi hemodialisis untuk mengurangi gejala uremik pruritus. Penelitiasn ini merupakan penelitian akupunktur pertama di Indonesia dengan subyek pasien hemodialisis. Tiga puluh tujuh pasien hemodialisis dengan uremik pruritus dibagi dalam dua kelompok secara acak, kelompok akupunktur (n=18) mendapat terapi akupunktur pada titik tunggal LI11 Quchi, sementara kelompok kontrol (n=19) mengunakan jarum plasebo The Park Sham Device. Terapi akupunktur dilakukan saat hemodialisis, seminggu dua kali sebanyak 12 kali. Skor pruritus dinilai menggunakan kuesioner pruritus 5D sebelum terapi, setelah terapi ke-4, ke-8 dan setelah terapi ke-12, serta penilaian lanjutan 4 dan 8 minggu setelah terapi selesai. Perbedaan bermakna skor pruritus 5D antara kelompok akupunktur dan kelompok kontrol terjadi setelah akhir terapi akupunktur (7,89±0,832 vs 10,63±3,166; p=0,003) dan penilaian lanjutan 4 minggu setelah terapi selesai(8,06±1,830 vs 10,95±3,341; p=0,001). Terapi akupunktur efektif menurunkan skor uremik pruritus pada pasien hemodialisis yang menjalani dialisis seminggu dua kali.

ABSTRACT
Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.;Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week., Uremic pruritus still gives problems for hemodialysis patients especially to reducing their quality of life, although it has been many advancements in dialysis techniques, recent therapies not yet provide optimum results. Acupuncture has a role as a complement in hemodialysis therapy to alleviate the symptoms of uremic pruritus in hemodialysis patients. This study is the first acupuncture research in Indonesia with the subject of hemodialysis patients. Thirty-seven hemodialysis patients with uremic pruritus were divided randomly into two groups, the acupuncture group (n = 18) received acupuncture treatment at a single point LI11 Quchi, while the control group (n = 19) using a placebo needle The Park Sham Device. Acupuncture treatment was done simultaneously with hemodialysis therapy, twice a week for 12 times. The pruritus scores was assessed using a 5D pruritus questionnaire before treatment, after 4th, 8th, 12th acupuncture treatment and at 4 and 8 weeks follow up. Significant differences 5D pruritus scores between the acupuncture group and the control group occurred after the end of acupuncture treatment (7.89±0.832 vs 10.63±3.166; p = 0.003) and at 4 weeks follow up (8.06±1.830 vs. 10.95±3.341; p = 0.001). Acupuncture treatment is effective in lowering the score of uremic pruritus in hemodialysis patients who undergo dialysis twice a week.]"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Edith Anggina
"ABSTRAK
Detrusor underactivity DU adalah berkurangnya kekuatan dan/atau durasi kontraksi yang mengakibatkan pengosongan kandung kemih yang memanjang atau inkomplit. Sebanyak enam pasien dengan diagnosis DU diinklusikan dalam penelitian ini. Akupunktur tanam benang dilakukan dengan menggunakan polydioxanone PDO yang ditusukkan di titik akupunktur BL33 dan CV3 dengan teknik penetrating needling. Akupunktur tanam benang dilakukan sebanyak satu kali. Transcutaneous tibial nerve stimulation TTNS dilakukan sebanyak 3 kali seminggu selama 4 minggu. Hasilnya penelitian menunjukkan tidak terdapat perbedaan bermakna antara rerata volume berkemih sebelum 72,00 70,48 dan setelah 158,17 139,58 akupunktur tanam benang dan TTNS, p = 0,115, namun didapatkan peningkatan dengan rerata 86,17 110,80. Tidak terdapat perbedaan bermakna antara nilai PVR sebelum 164,00 173,69 dan setelah 74,83 126,28 terapi, p = 0,151, namun didapatkan penurunan sebesar 89,17 129,07. Tidak terdapat perbedaan bermakna antara rerata Qmax sebelum 4,12 3,28 dan setelah 12,35 9,20 , p = 0,085, namun didapatkan peningkatan sebesar 8,23 9,41. Terdapat perbedaan bermakna antara skor kualitas hidup sebelum dan setelah terapi dengan p = 0,017. Kesimpulan : akupunktur tanam benang dan TTNS dapat meningkatkan volume berkemih, menurunkan PVR, dan meningkatkan Qmax penderita DU, dan dapat memperbaiki kualitas hidup penderita DU secara signifikan. ABSTRACT
Detrusor underactivity DU is a contraction of reduced strength and/or duration resulting in prolonged and/or incomplete bladder emptying. A total of six DU patients were included in this research. We did thread-embedding acupuncture by inserting polydioxanone PDO into BL33 and CV3 acupuncture points with penetrating needling techniques. Thread-embedding acupuncture was given once. Transcutaneous tibial nerve stimulation TTNS was given 3 times in a week during 4 weeks. The results showed no significant differences between before and after treatment on voided volume 72,00 70,48 and 158,17 139,58 , p = 0,115, but there was improvement with mean 86,17 110,80. There was no significant difference between before and after treatment on PVR 164,00 173,69 and 74,83 126,28 , p = 0,151, but there was improvement with mean 89,17 129,07. There was no significant difference between before and after treatment on Qmax 4,12 3,28 and 12,35 9,20 , p = 0,085, but there was improvement with mean 8,23 9,41. There was significant difference between before and after treatment on quality of life scoring with p = 0,017. Conclusion : thread embedding acupuncture and TTNS increase voided volume, and Qmax, decrease PVR, improve quality of life in in detrusor underactivity patients significantly "
2017
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UI - Tugas Akhir  Universitas Indonesia Library
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Newanda Mochtar
"ABSTRAK
Latar belakang:Migren adalah serangan nyeri kepala primer, bersifat spesifik,
paroksismal, dengan atau tanpa aura, dengan manifestasi subjektif baik sebelum
maupun sesudah serangan, merupakan nyeri kepala tipe kronik dengan gejala rekurensi,
menyerang usia produktif dan dapat menyebabkan penurunan produktivitas kerja hingga
80%, sehingga akan mempengaruhi kualitas hidup dan kehidupan perekonomian dan
pendidikan secara global yang mengarah kepada kerugian bagi penderita migren dan
institusi tempat penderita migren bersekolah ,bekerja serta dalam kehidupan keluarga
penderita. Dengan tingginya angka prevalensi dan disabilitas pada penderita migren,
dilain pihak sampai saat ini pengobatan yang tepat terhadap migren belum didapatkan
secara maksimal maka diperlukan pendalaman dalam pengobatan maupun pencegahan
migren sangat dibutuhkan., dan sampai saat ini belum didapatkan obat yang pasti, baik
terhadap pencegahan dan pengobatan, sehingga perlu dikembangkan terapi yang dapat
memberikan pertolongan yang lebih akurat pada penderita migren
Tujuan penelitian ini adalah menilai keberhasilan dalam penatalaksanaan migren dalam
mengurangi frekuensi serangan, mengurangi intensitas serangan dan mengurangi durasi
serangan dari minggu ke-0,ke-4 hingga ke-8. Metode: Uji klinis acak tersamar tunggal
dengan kontrol dilakukan terhadap 34 subjek dengan migren yang dialokasikan secara
acak kedalam kelompok manual akupunktur (n=17), serta kelompok medikamentosa
(n=17). Penilaian menilai frekuensi, durasi dan intensitas serangan migren yang dinilai
pada saat sebelum perlakuan, minggu ke-4 dan minggu ke-8 dari baseline. Hasil: Hasil
penelitian menunjukkan terdapat perbedaan bermakna antara kedua kelompok pada
rerata jumlah frekuensi (p=0,040), durasi (p=0,012) dan intensitas (p=0,003) serangan
migren pada minggu ke-4 dibandingkan dengan medikamentosa. Serata terdapat
perbedaan yang bermakna antara kedua kelompok pada rerata jumlah jumlah frekuensi
(p=0,029), durasi (p=0,001) dan intensitas (p<0,001) serangan migren pada minggu ke-
8. Kesimpulan: Intervensi akupunktur manual dapat menurunkan frekuensi, durasi dan
intensitas serangan migren lebih baik dibandingkan dengan preventif farmakologi asam
valproat pada minggu ke-4 dan minggu ke-8.

ABSTARCT
Migraine is a primary headache attack, specific, paroxysmal, with or without aura, with subjective manifestations both before and after the attack, a chronic
type of headache with symptoms of recurrence, attacks at productive age and can cause a decrease in work productivity up to 80%, so that it will affect the quality of life, economic life and education globally which leads to losses for migraine sufferers and
institutions where migraine sufferers attend school, work and in the lives of sufferers
families. With the high prevalence and disability rates for migraine sufferers, on the
other hand, the right treatment for migraine has not yet been obtained to the maximum,
it is necessary to deepen the treatment and prevention of migraine is needed, and until
now there has been no definitive cure, both for prevention and treatment, so it is
necessary to develop therapies that can provide more accurate relief for migraine
sufferers. The purpose of this study is to assess the success in managing migraine in
reducing the frequency of attacks, reducing the intensity of attacks and reducing the
duration of attacks from weeks 0, 4 to 8. Methods: A randomized controlled trial with
control was conducted on 34 subjects with migraine who were randomly allocated into
the manual group of acupuncture (n = 17), as well as the medicine group (n = 17). The
assessment of frequency, duration and intensity of migraine attacks assessed at the time
before treatment, at the fourth and eight week from baseline. Results: The results
showed there were significant differences between the two groups in the mean number
of frequencies (p = 0.040), duration (p = 0.012) and intensity (p = 0.003) of migraine
attacks at the fourth week. There were significant differences between the two groups in
the average number of frequencies (p= 0.029), duration (p=0.001) and intensity
(p<0.001) of migraine attacks at the eight week. Conclusion: Manual acupuncture
interventions can reduce the frequency, duration and intensity of migraine attacks
better than the use of valproic acid in the fourth and eight week."
2019
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UI - Tesis Membership  Universitas Indonesia Library
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Irman
"Pendahuluan: COVID-19 merupakan penyakit yang disebabkan oleh infeksi virus SARS-CoV-2. Gejala klinis COVID-19 yang paling sering dialami adalah demam dan batuk. Infeksi SARS-CoV-2 ke dalam tubuh pejamu akan menimbulkan respon imun dari pejamu yang akan menyebabkan terjadinya inflamasi sistemik. Hal ini dapat dilihat dari peningkatan berbagai penanda inflamasi, salah satunya adalah C-Reactive Protein (CRP). Saat ini belum ada terapi spesifik yang efektif untuk mengatasi COVID-19. Akupunktur yang merupakan modalitas terapi non-farmakologi yang telah terbukti dapat memberikan efek anti-inflamasi. Saat ini belum ada penelitian uji klinis akupunktur yang meneliti penanda inflamasi terhadap pasien COVID-19 yang telah dipublikasi. Tujuan penelitian ini adalah untuk mengetahui bagaimana efektivitas akupunktur dalam menurunkan kadar CRP dan memperbaiki gejala batuk yang dialami pasien COVID-19 gejala ringan-sedang.
Metode: Sebuah penelitian pilot dengan desain studi uji klinis acak tersamar tunggal. Dua puluh dua pasien COVID-19 terkonfirmasi melalui pemeriksaan RT-PCR yang memiliki gejala ringan-sedang yang sedang dirawat inap di rumah sakit dikelompokan dalam dua kelompok: kelompok perlakuan yang mendapat terapi standar dan intervensi akupunktur manual dan kelompok kontrol yang mendapat terapi standar. Intervensi akupunktir manual dilakukan setiap 2 hari dengan total 6 sesi terapi. Sebelum intervensi dilakukan pengukuran kadar CRP dan penentuan onset batuk dan setelah 6 sesi akupunktur dilakukan dilakukan pengukuran kadar CRP dan penentuan periode lama batuk.
Hasil: Terjadi penurunan rerata kadar CRP pada kedua kelompok (p=0,397). Penurunan kadar CRP pada kelompok perlakuan lebih besar dibandingkan kelompok kontrol. Gejala batuk lebih singkat pada kelompok perlakuan dibandingkan pada kelompok kontrol dan perbedaan ini bermakna secara statistik (p = 0,01).
Kesimpulan: Kombinasi akupunktur manual dan terapi standar menurunkan kadar CRP dan penurunannya lebih besar dibandingkan dengan terapi standar. Namun, penurunan kadar CRP tidak bermakna secara statistik. Dan mempersingkat gejala batuk yang dialami pasien COVID-19 gejala ringan-sedang secara bermakna.

Introduction: COVID-19 is a disease that caused by infection of SARS-CoV-2. The most common clinical symptoms of COVID-19 are fever and cough. SARS-CoV-2 infection into the host's body will cause an immune response which will cause systemic inflammation. This can be seen from the increase in various inflammatory markers, one of which is C-Reactive Protein (CRP). Currently there is no specific therapy that is effective for curing COVID-19. Acupuncture is a non-pharmacological therapeutic modality that has been shown to provide anti-inflammatory effects. Currently, there are no published studies of acupuncture clinical trials examining inflammatory markers in COVID-19 patients. The purpose of this study was to determine how effective acupuncture in reducing CRP levels and improving cough symptoms experienced by COVID-19 with mild-moderate symptoms patients.
Methods: A pilot study with an experimental study design single blind randomized clinical trial. Twenty-two COVID-19 patients confirmed by RT-PCR examination who had mild-moderate symptoms who were being hospitalized were divided into two groups: the treatment group who received standard therapy and manual acupuncture intervention and the control group who received standard therapy. Manual acupuncture intervention was performed every 2 days for a total of 6 therapy sessions. Before the intervention, the CRP level was measured and the onset of the cough was determined and after 6 acupuncture sessions, the CRP level was measured and the period of cough was determined.
Results: There was a decrease in the mean of CRP levels in both groups (p = 0.397). The decrease in CRP levels in the treatment group was greater than the control group. Cough symptoms were shorter in the treatment group than in the control group and this difference was statistically significant (p = 0.01).
Conclusion: The combination of manual acupuncture and standard therapy reduced CRP levels and the decrease was greater than that of standard therapy. However, the reduction in CRP levels was not statistically significant. And shorten the cough symptoms experienced by mild-moderate COVID-19 patients significantly.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Tugas Akhir  Universitas Indonesia Library
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Putu Bagus Surya Witantra Giri
"Penyakit Paru Obstruktif Kronik (PPOK) kini telah menjadi penyebab kematian terbanyak keempat di dunia. Masih tingginya angka mortalitas pada tatalaksana PPOK mengharuskan pengembangan modalitas terapi yang terus-menerus. Penelitian ini bertujuan untuk mengetahui pengaruh terapi kombinasi akupunktur tanam benang dan medikamentosa terhadap indeks BODE pasien PPOK. Uji klinis acak tersamar ganda dengan pembanding dilakukan terhadap 48 pasien yang dialokasikan ke dalam kelompok kasus (kombinasi akupunktur tanam benang dan medikamentosa) atau kelompok kontrol (kelompok akupunktur sham dan medikamentosa). Akupunktur tanam benang dilakukan pada titik BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu dan ST40 Fenglong sebanyak 2 kali dengan interval 15 hari. Indeks BODE sebagai keluaran primer dinilai pada hari ke-1 dan hari ke-30. Hasil penelitian menunjukkan perbedaan yang bermakna secara statistik maupun klinis antar kedua kelompok. Rerata penurunan indeks BODE 1,83 lebih rendah pada kelompok kasus dibandingkan dengan kelompok kontrol (p =0,000). Disimpulkan bahwa terapi kombinasi akupunktur tanam benang dan medikamentosa lebih efektif menurunkan Indeks BODE dibandingkan dengan medikamentosa saja.

Chronic Obstructive Pulmonary Disease (COPD) is now becoming the fourth leading cause of death in the world. Since high level of mortality following COPD medication, continous research to improve treatment modalities keeps on progressing. This study aimed to establish the effect of acupoint-catgut embedment combined with medical treatment on BODE index of COPD patient. A double blind randomized controlled trial has been conducted on 48 patient allocated into acupoint-catgut embedment with medication group (case group) or sham acupuncture with medication group (control group). Acupoint-catgut embedment was done on BL13 Feishu, BL43 Gaohuangshu, BL20 Pishu, BL23 Shenshu and ST40 Fenglong, 2 times with interval 15 days. BODE index as primary outcome was assessed on day-1 and day-30. The result shown statistically and clinically important difference between groups. BODE index was reduced 1,83 point lower in case group (p = 0,000). By that result, acupoint-catgut embedment combined with medical treatment is concluded more effective than medical treatment solely in reducing BODE index."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2014
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Robin Martilo Djajadi
"Pendahuluan: Peningkatan kadar kolesterol didalam plasma darah atau hiperlipidemia merupakan faktor predisposisi terjadinya aterosklerosis. Faktor risiko diet tinggi lemak amat mempengaruhi tingginya kadar kolesterol darah. Permasalahan kepatuhan dalam perubahan diet dan efek samping obat penurun kolesterol menjadi alasan perlunya terapi pilihan lain yang aman dan efektif. Penelitian menunjukkan bahwa elektroakupunktur pada titik ST40 Fenglong dapat digunakan sebagai terapi untuk memperbaiki kadar kolesterol darah. Salah satu modalitas akupunktur yang sedang berkembang adalah laser akupunktur. Tujuan penelitian ini adalah untuk mengetahui bagaimana efektivitas laser akupunktur dibandingkan dengan elektroakupunktur pada titik ST40 Fenglong dalam memperbaiki kadar kolesterol otal, indeks aterogenik, dan berat lemak dinding abdomen pada tikus model diet tinggi lemak.
Metode: Desain studi ini adalah studi eksperimental dengan randomised control group posttest only. Dua puluh empat tikus Wistar jantan, usia 10 minggu dengan berat badan 200–250 gram dibagi menjadi 4 kelompok yaitu: kelompok diet normal, kelompok diet tinggi lemak tanpa perlakuan akupunktur, kelompok diet tinggi lemak dengan elektroakupunktur dan kelompok diet tinggi lemak dengan laser akupunktur. Elektroakupunktur dan laser akupunktur dilakukan 3 kali seminggu dengan total 12 sesi. Dilakukan pengukuran kadar kolesterol total, indeks aterogenik, dan berat lemak dinding abdomen setelah 12 sesi.
Hasil: Rerata kadar kolesterol total, indeks aterogenik, dan berat lemak dinding abdomen pada kelompok tikus model diet tinggi lemak yang mendapat laser akupunktur lebih rendah dibandingkan pada kelompok tikus model diet tinggi lemak yang mendapat elektroakupunktur, namun tidak berbeda bermakna secara statistik (p > 0,05).
Kesimpulan: Laser akupunktur memiliki kecenderungan lebih baik dalam mencegah peningkatan kolesterol total, indeks aterogenik, dan peningkatan berat lemak dinding abdomen akibat konsumsi diet tinggi lemak dibandingkan dengan elektroakupunktur
Introduction: Hyperlipidemia is an increased concentration of fat in blood plasma and is a predisposing factor for atherosclerosis. Risk factor such as high-fat diet greatly affect blood cholesterol levels. The problem of adherence to diet changes and cholesterol medication side effects are reasons to look for other alternative therapies that are safe and effective. Research shows that electroacupuncture at the ST40 Fenglong point can be used as a therapy to improve blood cholesterol levels. One of the acupuncture modalities is laser acupuncture. The purpose of this study was to determine the effectiveness of laser acupuncture compared to electroacupuncture at the ST40 Fenglong point for improving total cholesterol levels, atherogenic index, and abdominal wall fat weight in high fat diet model rats.
Methods: This study was an experimental study with posttest only randomized control group. Twenty-four male Wistar rats, aged 10 weeks with a body weight of 200–250 grams were divided into 4 groups: the normal diet group, the high-fat diet without acupuncture treatment group, the high-fat diet with electroacupuncture group and the high-fat diet with laser acupuncture group. Electroacupuncture and laser acupuncture treatments were performed 3 times a week for a total of 12 sessions. Total cholesterol levels, atherogenic index, and abdominal wall fat weight were measured after 12 sessions.
Results: The mean total cholesterol levels, atherogenic index, and weight of abdominal wall fat in the high-fat diet model group which received laser acupuncture treatment was lower than that in the high-fat diet group which received electroacupuncture group, but did not significantly differ (p> 0.05).
Conclusion: Compared to electroacupuncture, laser acupuncture has a better tendency at preventing increases in total cholesterol level, atherogenic index, and abdominal wall fat weight due to high-fat diet consumption."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
cover
Rachma Novita Indrarini
"ABSTRAK
Latihan fisik merupakan hal yang penting untuk kesehatan namun dapat pula meningkatkan stres oksidatif yang menyebabkan peningkatan Reactive Oxygen Species ROS . Superoksida dismutase SOD adalah antioksidan endogen yang terdapat dalam tubuh, merupakan enzim yang mengkatalisis dismutasi ion superoksida radikal O2- menjadi hidrogen peroksida H2O2 dan molekul oksogen O2 sebagai perlawanan terhadap stres oksidatif.Akupunktur merupakan salah satu modalitas terapi yang diharapkan dapat mengurangi stress oksidatif yang terjadi akibat latihan fisik. Penelitian ini dilakukan pada tiga puluh pria tidak terlatih yang dibagi secara acak menjadi dua kelompok, kelompok akupunktur manual n = 15 yang dilakukan penusukan pada titik akupunktur ST36 dan SP6 bilateral, dan kelompok plasebo n = 15 yang dilakukan penusukan jarum pada plester tanpa menembus kulit. Terapi akupunktur dilakukan satu kali selama 30 menit segera setelah subyek selesai melakukan latihan fisik akut.. Penilaian kadar SOD darah dinilai sebelum latihan fisik dan satu jam setelah melakukan latihan fisik. Hasil penelitian ini menunjukkan terdapat perbedaan bermakna secara statistik selisih kadar SOD antara sebelum dan sesudah latihan fisik antara kelompok akupunktur manual dan kelompok plasebo p = 0,001.

ABSTRACT
Physical exercise is important for health but can also increase oxidative stress that induce Reactive Oxygen Species ROS . Superoxide dismutase SOD is endogenous antioxidants found in the body, an enzyme that catalyzes the dismutation of radical superoxide ions O2 into hydrogen peroxide H2O2 and oxygen molecules O2 against oxidative stress Acupuncture is one of the therapeutic modalities that is expected to reduce oxidative stress that occurs due to physical exercise. The study was conducted on thirty untrained men who were randomly divided into two groups, the manual acupuncture group n 15 performed acupuncture therapy at bilateral ST36 and SP6 acupuncture points, and the placebo group n 15 performed the needle stitching on the plaster without penetrating the skin. Acupuncture therapy is performed once for 30 minutes immediately after the subjects have finished acute physical exercise. Assessment of the blood SOD level was assessed before physical exercise and one hour after physical exercise. The results of this study showed a statistically significant difference in the difference between the level of SOD before and after physical exercise between the manual acupuncture group and placebo group p 0.001. "
2017
SP-Pdf
UI - Tugas Akhir  Universitas Indonesia Library
cover
Nila Marwiyah
"[ABSTRAK
Nyeri dan kecemasan merupakan hal yang normal ketika ibu menghadapi
persalinan, namun jika mengalami nyeri dan kecemasan yang berlebihan akan
menimbulkan komplikasi selama proses persalinan. Penelitian ini bertujuan untuk
mengetahui pengaruh paket Touching, Massage, Acupressure (T.M.A) oleh
keluarga terhadap nyeri persalinan dan proses persalinan. Penelitian ini
merupakan operasional research. Sampel dalam penelitian ini 94 ibu hamil yang
dibagi menjadi dua kelompok yaitu 47 orang sebagai kelompok intervensi dan 47
kelompok kontrol yang diambil dengan teknik consecutive sampling.
Pengumpulan data menggunakan kuesioner FPRS, FAS, lembar observasi proses
persalinan dan wawancara. Hasil wawancara keluarga mengatakan bahwa
pengetahuan keluarga bertambah dan adanya manfaat setelah penerapan paket
T.M.A. Hasil uji statistik dengan menggunakan Chi Square menunjukan bahwa
ada perbedaan yang bermakna pada proses persalinan (power, p=0,028);
passanger p=0,006; passageway p=0,048; position p=0,048; psikologis p=0,000)
dan nyeri persalinan (p=0,003) antara kedua kelompok intervensi dan kontrol. Hal
ini menunjukan bahwa pendampingan keluarga dengan menggunakan paket
T.M.A berpengaruh terhadap proses persalinan dan nyeri persalinan. Paket T.M.A
diharapkan menjadi intervensi non farmakologis dalam keperawatan untuk
menurunkan nyeri dan kecemasan pada ibu bersalin.

ABSTRAK
Pain and anxiety is normal when a mother facing labor. Excessive pain and
anxiety will cause complications during childbirth. This research aimed to know
the effect of touching package, Massage, Acupressure (TMA) by the family to the
pain of labor and delivery process. This research operasional research. The
sample were 94 pregnant women that divided into two groups: 47 as intervention
group and 47 control group that taken with consecutive sampling technique.
Collection data using questionnaires FPRS, FAS and observation sheet delivery
process. The results obtained in the interview, participant said that family
knowledge has increased and they feel the benefit of the TMA package. The
quantitatif result showed there was a significant difference in labor process
(power, p=0,028); passenger p=0,006; passageway p=0,048; position p=0,048;
psychological response p=0,000) and pain (p=0,003) between the intervention and
control groups. This shows that the family what used TMA package influence on
labor process and pain. Touching package, Massage, Acupressure (TMA) is
expected as an intervention non farmakologis in decreased pain and anxiety
maternal.;Pain and anxiety is normal when a mother facing labor. Excessive pain and
anxiety will cause complications during childbirth. This research aimed to know
the effect of touching package, Massage, Acupressure (TMA) by the family to the
pain of labor and delivery process. This research operasional research. The
sample were 94 pregnant women that divided into two groups: 47 as intervention
group and 47 control group that taken with consecutive sampling technique.
Collection data using questionnaires FPRS, FAS and observation sheet delivery
process. The results obtained in the interview, participant said that family
knowledge has increased and they feel the benefit of the TMA package. The
quantitatif result showed there was a significant difference in labor process
(power, p=0,028); passenger p=0,006; passageway p=0,048; position p=0,048;
psychological response p=0,000) and pain (p=0,003) between the intervention and
control groups. This shows that the family what used TMA package influence on
labor process and pain. Touching package, Massage, Acupressure (TMA) is
expected as an intervention non farmakologis in decreased pain and anxiety
maternal.;Pain and anxiety is normal when a mother facing labor. Excessive pain and
anxiety will cause complications during childbirth. This research aimed to know
the effect of touching package, Massage, Acupressure (TMA) by the family to the
pain of labor and delivery process. This research operasional research. The
sample were 94 pregnant women that divided into two groups: 47 as intervention
group and 47 control group that taken with consecutive sampling technique.
Collection data using questionnaires FPRS, FAS and observation sheet delivery
process. The results obtained in the interview, participant said that family
knowledge has increased and they feel the benefit of the TMA package. The
quantitatif result showed there was a significant difference in labor process
(power, p=0,028); passenger p=0,006; passageway p=0,048; position p=0,048;
psychological response p=0,000) and pain (p=0,003) between the intervention and
control groups. This shows that the family what used TMA package influence on
labor process and pain. Touching package, Massage, Acupressure (TMA) is
expected as an intervention non farmakologis in decreased pain and anxiety
maternal., Pain and anxiety is normal when a mother facing labor. Excessive pain and
anxiety will cause complications during childbirth. This research aimed to know
the effect of touching package, Massage, Acupressure (TMA) by the family to the
pain of labor and delivery process. This research operasional research. The
sample were 94 pregnant women that divided into two groups: 47 as intervention
group and 47 control group that taken with consecutive sampling technique.
Collection data using questionnaires FPRS, FAS and observation sheet delivery
process. The results obtained in the interview, participant said that family
knowledge has increased and they feel the benefit of the TMA package. The
quantitatif result showed there was a significant difference in labor process
(power, p=0,028); passenger p=0,006; passageway p=0,048; position p=0,048;
psychological response p=0,000) and pain (p=0,003) between the intervention and
control groups. This shows that the family what used TMA package influence on
labor process and pain. Touching package, Massage, Acupressure (TMA) is
expected as an intervention non farmakologis in decreased pain and anxiety
maternal.]"
2015
T42987
UI - Tesis Membership  Universitas Indonesia Library
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