Hasil Pencarian  ::  Simpan CSV :: Kembali

"

---

ABSTRACTSince the publication of the first edition of the Handbook of Human Immunology in 1997, major scientific achievements have directly contributed to an increased understanding of the complexities of the human immune system in health and disease. Whether as a result of the sequencing of the entire human genome, or of technological advancements, several new components of the immune system have been revealed, along with new technologies for their measurement and evaluation.Major breakthroughs in the field include an increase in the number of recognized "clusters of differentiation" on the surface of leukocytes and associated cells, the establishment of a chemokine and chemokine receptor nomenclature system, the discovery of more than 30 lymphokines, and humanized monoclonal antibody therapy as a staple of pharmacologic armamentarium.Modeling the previous edition, the text begins with an overview of the immune system, focusing on the role of cell receptors, accessory molecules, and cytokines in immune responses and immunological disorders. It then presents a practical, easy-to-read chapter on "statistics in immunological testing" an invaluable asset for interpreting test results, validating new tests, and developing reference ranges. Simultaneously, the text emphasizes clinically relevant immunological parameters and clarifies the basic principles underlying immune system assays, and applications and interpretations of immune tests. A complete guide to molecular and cellular immunology for practicing clinicians, clinical laboratory professionals, and students, this resource combines basic explanations of laboratory tests with more than 100 tables full of references, and up-to-date information on new developments in immunogenetics. "

"ABSTRAKThe existence of chioramphenicol residues in veterinary products could cause such a serious side effect like aplastic anemia. A specific and sensitive ELISA method to detect chioramphenicol residues was needed to be developed in order to get a more efficient and economical analysing method. In this study, a direct ELISA method has been done using chioramphenicol-bovine serum albumin (CAP-BSA) as antigen and antisera chioramphenicol labelled by enzyme horseradish peroxidase (HRP) as antibody. CAP-BSA with a dilution of 1:200 and antisera chioramphenicol labelled by }iRP with a dilution of 1:125 showed a limit detection of 0.05 ng/ml. CAP-BSA had been synthesized from chloramphenicol sodium succinate and BSA, using mixed anhydride reaction, whereas HRP-labelled antisera chloramphenicol had been synthesized from antisera chioramphenicol and FIRP, using periodate conjugation technique. The production of antisera chloramphenicol has been performed through CAP-BSA immunization using two New Zealand White rabbits resulting in antisera chloramphenicol with a less satisfactory specificity and sensitivity. The recovery assay of chloramphemcol in cow milk gave 98,17% ± 2,88% yield.

---

"

"The aim of this volume is to summarize current knowledge on the cellular and molecular aspects of the aging immune system, with an emphasis on infectious diseases and new therapeutic approaches."