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"Penelitian ini bertujuan untuk melihat pengaruh work engagement dan resistensi perubahan (resistance to change) dengan komitmen afektif untuk perubahan (affective commitment to change) dan intervensi yang dapat dilakukan untuk meningkatkan komitmen afektif untuk perubahan. Penelitian dilakukan pada perusahaan yang bergerak di layanan kebandaraan dengan partisipan dikhususkan pada karyawan operasional yang melibatkan sebanyak 260 karyawan. Pengambilan data partisipan dilakukan melalui kuesioner daring dengan kuesioner yang terdiri atas komitmen afektif untuk perubahan, resistensi perubahan dan work engagement. hasil analisis data menunjukkan bahwa resistensi perubahan memiliki hubungan negatif dan signifikan dengan komitmen afektif untuk perubahan. Work engagement juga memiliki hubungan yang positif dan signifikan dengan komitmen afektif terhadap perubahan. Dari hasil regresi didapatkan bahwa pada penelitian ini, pengaruh resistensi perubahan dengan komitmen afektif untuk perubahan lebih besar dibandingkan dengan pengaruh work engagement. Pada penelitian ini, intervensi pelatihan komunikasi perubahan telah dilakukan pada karyawan operasional (22 orang) dengan hasil menunjukkan adanya peningkatan pengetahuan perubahan organisasi secara signifikan melalui evaluasi level 2.

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This study was aimed to determine the influence of work engagement and resistance to change on affective commitment to change and training intervention design to enhance affective commitment to change. The research was conducted at airport services company with participants of operational employees as 260 employees. The data was collected by online questionnaire with a questionnaire consisting of affective commitment to change, resistance to change and work engagement. The results showed resistance to change has a significant negative relationship with affective commitment to change. Work engagement also has a significant positive relationship with affective commitment to change. In this study, the result using regression show that resistance to change was better effect on affective commitment to change than work engagement. Following this study the intervention was done for operational employees (22 peoples) on change communication, and the results showed that change communication intervention increased knowledge of organizational change significantly through evaluation level 2."

"Untuk dapat merasa bahagia, kemampuan individu dalam melakukan inhibitory control terhadap informasi negatif yang tidak relevan sangatlah penting. Namun, kondisi emosional yang bersifat sementara seperti mood dan perubahan afek positif dikenal dapat memengaruhi performa fungsi kognitif ini. Penelitian ini bertujuan untuk melihat hubungan antara inhibitory control dan tingkat kebahagiaan dengan mood dan perubahan afek positif sebagai moderator. Sebanyak 119 partisipan yang sehat mental berusia 18 - 35 tahun (M = 21,5 tahun) berpartisipasi dalam penelitian ini. Sejumlah 59 partisipan menerima induksi mood positif dan 60 orang menerima induksi mood netral. Tingkat kebahagiaan diukur menggunakan Subjective Happiness Scale (Lyubomirsky & Lepper, 1999), mood diukur menggunakan The Positive and Negative Affect Schedule (Watson et al., 1988), sedangkan perubahan afek positif diukur dari selisih penilaian afek positif sebelum (Pre PA) dan setelah (Post PA) induksi mood dilakukan. Performa inhibitory control untuk informasi negatif diukur menggunakan tugas Negative Affective Priming. Hasil analisis moderasi dengan PROCESS model 2 menunjukkan bahwa performa inhibitory control untuk informasi negatif adalah prediktor positif dan signifikan untuk tingkat kebahagiaan. Mood memoderasi secara signifikan hubungan antara performa inhibitory control terhadap informasi negatif dan tingkat kebahagiaan, tetapi perubahan afek positif tidak memoderasi hubungan ini. Selain itu, berdasarkan analisis moderasi PROCESS model 1, pada kondisi mood netral, terdapat korelasi positif antara inhibitory control untuk informasi negatif dan tingkat kebahagiaan. Sebaliknya, pada kondisi mood positif, terdapat korelasi negatif antara inhibitory control untuk informasi negatif dan tingkat kebahagiaan. Temuan dalam penelitian ini menunjukkan bahwa dinamika hubungan antara performa inhibitory control dalam menghambat informasi negatif dan tingkat kebahagiaan dipengaruhi oleh mood partisipan.

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Largely influenced by moodIn order to be happy, it is important to hone the ability to inhibit irrelevant negative information. However, temporary emotional states such as mood and changes in positive affect are known to affect the performance of inhibitory control. The current study aimed to examine the moderating roles of mood and changes in positive affect on the relationship between inhibitory control and happiness. A total of 119 mentally healthy participants aged 18-35 years (M = 21.5 years) participated in this study. Fifty-nine participants received positive mood induction and 60 participants received neutral mood induction. Happiness was measured using the Subjective Happiness Scale (Lyubomirsky & Lepper, 1999), mood was measured using The Positive and Negative Affect Schedule (Watson et al., 1988), while changes in positive affect was measured by calculating the difference between the levels of positive affect before (Pre PA) and after (Post PA) the mood induction procedure. Inhibitory control performance for irrelevant negative information was measured using Negative Affective Priming Task. The results of the moderation analysis using PROCESS model 2 showed that inhibitory control performance for negative information was a significant and positive predictor for happiness. Interestingly, mood significantly moderated the relationship between inhibitory control for negative information and happiness, but changes in positive affect did not moderate this relationship. Based on analysis using PROCESS model 1, in neutral mood condition, there was a positive correlation between inhibitory control for negative information and happiness. Conversely, in positive mood condition, there was a negative correlation between inhibitory control for negative information and happiness. Thus, the findings of this study suggest that the relationship between inhibitory control for irrelevant negative information and happiness is largely influenced by mood."

"This volume discusses the current state of research findings related to healthy brain aging by integrating human clinical studies and translational research in animal models. Several chapters offer a unique overview of successful aging, age-related cognitive decline and its associated structural and functional brain changes, as well as how these changes are influenced by reproductive aging. Insights provided by preclinical studies in mouse models and advanced neuroimaging techniques in humans are also presented."

"Pemeriksaan HRCT toraks mengevaluasi secara objektif perubahan pada gambaran parenkim paru akibat respons inflamasi termasuk pada pasien pasca COVID-19. Riwayat terapi selama pasien dirawatinapkan merupakan faktor yang diduga berpengaruh terhadap gambaran HRCT toraks pasca COVID-19. Penelitian ini menganalisis hubungan antara riwayat terapi tersebut dengan gambaran HRCT toraks dengan subjek yang diperiksakan antara Juni 2020-Juli 2021. Metode yang digunakan adalah observasional analitik dengan pendekatan kohort pada data sekunder melalui telusur rekam medis. Pada 73 subjek penelitian dilakukan analisis univariat, bivariat (uji kai kuadrat dan fisher) dan multivariat (uji regresi logistik) dengan variabel independen terdiri atas karakteristik individu (usia, jenis kelamin, komorbiditas, derajat COVID-19) dan riwayat terapi (antivirus, antiinflamasi dan antitrombotik) serta variabel dependen berupa gambaran HRCT toraks. Terdapat gambaran sekuele sebanyak 55 subjek (75,3%) dengan rincian 7 subjek (9,6%) dengan gambaran fibrosis, 5 subjek (6,8%) dengan gambaran GGO, 43 subjek (59,9%) dengan gambaran GGO dan fibrosis serta gambaran nonsekuele sebanyak 18 subjek (24,7%). Gambaran sekuele terhadap variabel masing-masing adalah sebagai berikut: laki-laki dan perempuan yaitu 78,8% dan 66,7% (p=0,025, OR= 0,019-0,770), derajat ringan, sedang dan berat-kritis yaitu 56,5%, 75,0% dan 88,2% (p=0,031-1,096-6,962), subjek dengan dan tanpa warfarin yaitu 57,1% dan 82,7% (p=0,007, OR=0,016-0,517), subjek dengan dan tanpa heparin yaitu 83,3% dan 60,0% (p=0,024, OR= 1,250-23,222), subjek dengan durasi terapi antiinflamasi ≤10 hari dan >10 hari yaitu 61,0% dan 93,5% (p=0,026, OR=1,276-42,609). Laki-laki-laki lebih banyak memiliki gambaran sekuele pasca COVID-19 pada HRCT toraks daripada perempuan. Derajat COVID-19 adalah faktor paling berpengaruh dan menentukan pemilihan terapi rawat inap. Kelompok subjek dengan warfarin memiliki gambaran sekuele pasca COVID-19 pada HRCT toraks lebih banyak daripada tanpa warfarin. Kelompok subjek dengan heparin memiliki gambaran sekuele pasca COVID-19 pada HRCT toraks lebih banyak daripada tanpa heparin. Kelompok subjek dengan durasi terapi antiinflamasi ≤10 hari memiliki gambaran sekuele pasca COVID-19 pada HRCT toraks lebih sedikit daripada dengan terapi antiinflamasi >10 hari.

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Chest HRCT is an objective examination to evaluate alteration in lung parenchyma due to inflammation response including in post COVID-19 patients. Inward patient therapy history is one of factor to be suspected has an influence to chest HRCT features in post COVID-19 patients. This study analyzes a relation between therapy history and chest HRCT features was examined between June 2020 and June 2021. Observational analytic with retrospective approach method is used by medical record explore as secondary data. In 73 subjects in this study, univariate analysis, bivariate analysis (chi square and fisher’s test), and multivariate analysis (logistic regression) had done to perform the description of independent variable consists individual characteristics (age, sex, comorbidity, COVID-19 severity degree) and therapy history (antiviral, antiinflammation, antithrombotic), and chest HRCT features as dependent variable. There are sequelae features in 55 subjects (75.3%) consist of 7 subjects (9.6%) with fibrotic features, 5 subjects (6.8%) with GGO and 43 subjects (59.9%) and also 18 subjects (24.7%) non-sequelae features. Sequelae features for each variable are: male and female are 78,8% vs 66,7% (p=0.025, OR= 0.019-0.770), mild, moderate, and severe-critical COVID-19 severity degree are 56,5% vs 75,0% vs 88,2% (p=0,031-1,096-6,962), subjects with and without warfarin are 57,1% vs 82,7% (p=0,007, OR=0,016-0,517), subjects with and without heparin are 83,3% vs 60,0% (p=0,024, OR= 1,250-23,222), subject with antiinflammation therapy duration ≤10 days is higher risk than >10 days are 61,0% vs 93,5% (p=0,026, OR=1,276-42,609). Males are larger number with post COVID-19 sequelae features in chest HRCT than females. The severity degree of COVID-19 is the most influencing factor and this determines on inpatient therapy selection. Warfarin history subjects are smaller number with post COVID-19 sequelae features in chest HRCT than in without warfarin. Heparin history subjects are larger number with post COVID-19 sequelae features in chest HRCT than in without heparin. Anti-inflammatory therapy duration ≤10 days are smaller number with post COVID-19 sequelae features in chest HRCT than in > 10 days."

"Principles of toxicology : environmental and industrial applications, this edition provides health protection professionals as well as environmental scientists with precise, up-to-date, practical information on how to apply the science of toxicology in both the occupational and environmental setting. Through contributions from leading experts in diverse fields. Principles of toxicology, second edition features :

• - Clear explanations of the fundamentals necessary for an understanding of the effects of chemical hazards on human health and ecosystems
• - Coverage of occupational medicine and epidemiological issues
• - The manifestation of toxic agents such as metals, pesticides, organic solvents, and natural toxins
• - Special emphasis on the evaluation and control of toxic hazards
• - Specific case histories on applying risk assessment methods in the modern workplace
• - Ample figures, references, and a comprehensive glossary of toxicological terms

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