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Ditemukan 18654 dokumen yang sesuai dengan query
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Artikel Jurnal  Universitas Indonesia Library
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"Sindroma pemanjangan QT (Long QT syndrome) diakibatkan oleh defek genetik, merupakan kasus jarang, sering disertai dengan takikardia ventricular polimorfik (‘torsade de pointes’- TdP) dan dapat menyebabkan kematian mendadak. Dilaporkan kasus seorang wanita 25 tahun dengan riwayat berdebar, sakit kepala dan pingsan yang berulang sejak usia 16 tahun. Rekaman elektrokardiogram menunjukkan adanya ekstra-sistol ventrikular bigemini, interval QT terkoreksi memanjang dan gelombang T abnormal. Pascapersalinan pertama penderita didiagnosis sebagai kardiomiopati peripartal. Juli 2002 dirawat karena masalah pingsan dan kejang disertai TdP dan fibrilasi ventrikular. Keadaan ini dapat diatasi dengan beberapa kali pemberian renjatan aliran arus searah (DC), pemasangan pacu jantung sementara dengan laju jantung yang relatif tinggi. Penderita dipulangkan dengan penyekat beta dan pemasangan pacu-jantung tetap kamar ganda. Selama 4 bulan pemantauan, penderita tanpa keluhan. (Med J Indones 2003; 12: 109-13)

Long QT syndrome (LQTS) is an uncommon disease due to genetic defect and responsible for polymorphic VT (torsade-de pointes-TdP) and sudden cardiac death. A case of 25 year-old woman with palpitation, severe headache and recurrent syncopal episode since 16 year-old is reported. The ECG showed bigeminy ventricular premaure contraction (VPC), prolonged QTc interval and abnormal T wave. Peripartal cardiomyopathy was diagnosed recently after the first delivery. In July 2002, she was hospitalized due to recurrent syncope, seizure proceeded by TdP and VF. On admission she need several times DC shock and temporary pacemaker with relatively high rate. Beta-blocker and implantation of dual chamber permanent pacemaker finally could control the malignant arrhythmias. During follow-up for 4 months, she was doing well and no syncopal episode occurred. (Med J Indones 2003; 12: 109-13)"
Medical Journal of Indonesia, 12 (2) April June 2003:109-113, 2003
MJIN-12-2-AprilJune2003-109
Artikel Jurnal  Universitas Indonesia Library
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Herbowo Agung F. Soetomenggolo
"[ABSTRAK
Latar belakang Long QT syndrome LQTS adalah gangguan irama jantung bergejala kejang yang harus dikenali sejak dini karena dapat menyebabkan kematian mendadak Tujuan Mengetahui angka kejadian LQTS pada pasien dengan keluhan kejang serta karakteristiknya Metode Studi potong lintang terhadap anak yang pernah mengalami kejang tanpa provokasi di poliklinik neurologi anak RSUPN Cipto Mangunkusumo Subyek berusia 6 bulan hingga 17 tahun Panjang QT interval diukur menggunakan EKG dan dinilai menggunakan metode Bazzet Hasil Seratus empat puluh enam pasien kejang mengikuti penelitian ini Usia subyek jenis kelamin serta jenis kejang memiliki sebaran cukup merata Pada penelitian ini didapatkan kelainan penyerta kejang seperti tuli sensorineural autisme keterlambatan perkembangan menyeluruh disabilitas intelektual dan sindroma Rett Sebanyak 20 6 mengalami epilepsi intraktabel Tidak ditemukan subyek dengan pencetus kejang aktivitas fisik dan stres emosional dan hanya 2 7 memiliki riwayat keluarga meninggal mendadak Hasil penilaian QTc pada seluruh subyek di bawah 0 44 detik Nilai QTc terpendek adalah 0 333 detik dan nilai QTc terpanjang adalah 0 437 Nilai tersebut masih dalam rentang normal QTc pada anak Simpulan Pada penelitian ini tidak didapatkan pemanjangan QTc baik pada penderita kejang umum maupun fokal ABSTRACT Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures ; Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures , Background Long QT syndrome LQTS is a heart rhythm disorder with symptom of seizures that should be identified early because it can cause sudden death Aim Knowing the prevalence of LQTS in patients with symptom of seizures and characteristics Method A cross sectional study of children who have experienced an unprovoked seizure in child neurology clinic Cipto Mangunkusumo Subjects aged 6 months to 17 years QT interval was measured by ECG and assessed with Bazzet rsquo s formula Results One hundred and forty six patients with seizures were followed in this study The age sex and seizure rsquo s type of subject distributed evenly In this study we found some disorder along with seizure such as sensorineural deafness autism global developmental delay intellectual disability and Rett syndrome A total of 20 6 had intractable epilepsy We didn rsquo t find subject with physical activity and emotional stress as the trigger of seizure and only 2 7 had a family history of sudden death QTc assessment results in all subjects were under 0 44 seconds The shortest QTc values was 0 333 seconds and the longest QTc value was 0 437 seconds This value is still within the normal range QTc in children Conclusion In this study we concluded that we found no QTc prolongation in patients with seizures ]"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Ari Fahrial Syam
"Coronavirus disease 19 (COVID-19) which is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), has been a problem worldwide, particularly due to the high rate of transmission and wide range of clinical manifestations. Acute respiratory distress syndrome (ARDS) and multiorgan failure are the most common events observed in severe cases and can be fatal. Cytokine storm syndrome emerges as one of the possibilities for the development of ARDS and multiorgan failure in severe cases of COVID-19. This case report describes a case of a 53-year-old male patient who has been diagnosed with COVID-19. Further evaluation in this patient showed that there was a marked increase in IL-6 level in blood accompanied with hyperferritinemia, which was in accordance with the characteristic of cytokine storm syndrome. Patient was treated with tocilizumab, a monoclonal antibody and is an antagonist to IL-6 receptor. The binding between tocilizumab and IL-6 receptors effectively inhibit and manage cytokine storm syndrome. Although this case report reported the efficacy of tocilizumab in managing cytokine storm syndrome, tocilizumab has several adverse effects requiring close monitoring. Further clinical randomized control trial is required to evaluate the efficacy and safety of tocilizumab administration in participants with various clinical characteristics and greater number of subjects. "
Jakarta: University of Indonesia. Faculty of Medicine, 2021
610 UI-IJIM 53:2 (2021)
Artikel Jurnal  Universitas Indonesia Library
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Dalheimer, Matthias Kalle
Cambridge, UK: O'Reilly, 1999
005.428 DAL p
Buku Teks SO  Universitas Indonesia Library
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Agoes Kooshartoro
"Latar Belakang : Indonesia memiliki angka kematian karena penyakit kardiovaskular yang semakin meningkat, dengan angka kematian diperkirakan sebanyak 17,3 juta kematian. Mengingat tingkat mortalitas yang sangat tinggi pada pasien dengan sindrom koroner akut SKA, maka diperlukan sebuah prediktor Major Adverse Cardiac Event MACE yang objektif dan terukur untuk manajemen pasien SKA dalam jangka panjang. Pada SKA dapat ditemukan heterogenitas repolarisasi ventrikel yang dapat dilihat pada elektrokardiografi EKG sebagai QTmax-QTmin, atau dapat disebut sebagai QTD.QTD disinyalir dapat dijadikan penanda untuk risiko MACE pada pasien SKA.
Tujuan : Mengetahui peran dispersi QT dan QTcD sebagai prediktor MACE pada pasien sindrom koroner akut SKA.
Metode : Penelitian ini merupakan studi kohort retrospektif pada 230 rekam medis pasien SKA yang dirawat di ICCU RSCM dalam rentang waktu Januari 2016 hingga November 2017. EKG standar 12 sadapan saat serangan dianalisis dan dilakukan pengukuran interval QTmax dan QTmin yang kemudian dihitung QTd. Selanjutnya dikoreksi dengan frekuensi nadi menggunakan rumus Bazett QTcD.
Hasil : Pemanjangan QTD lebih dari 100mdet dapat menjadi prediktor MACE pada pasien dengan SKA OR 1,25 IK95 0,17 ndash; 2,71 . Setelah dikoreksi dengan frekuensi nadi menggunakan rumus Bazett, pemanjangan QTcD juga dapat menjadi prediktor MACE pada pasien SKA 1,89 IK95 0,05 ndash; 67,37.
Kesimpulan : Pemanjangan QTD lebih dari 100mdet atau QTcD lebih dari 12,72mdet dapat menjadi prediktor MACE.

Background: In Indonesia, the number of death due to cardiovascular disease is rapidly rising and it was approximated to have resulted in 17,3 million deaths. Due to this steadily increasing cases, it is necessary to find a predictor for Major Adverse Cardiac Event MACE that is objective and standardized for long term care of patients with acute coronary syndrome ACS. In ACS, one of the underlying mechanisms is the presence of heterogeneity in ventricle repolarization that is seen on ECG machine as QTmax ndash QTmin, or what is identified as QTD. QTD is hypothesized to have role as marker in patients with MACE in ACS.
Aim: Identify the role of QTD and QTcD as MACE predictor in patients with acute coronary syndrome.
Methods: This study is a retrospective cohort with the subject of 230 ACS patients that was hospitalised on RSCM ICCU among January 2016 to November 2017. Data was taken from medical record and 12 lead ECG during attack were taken and analysed manually to calculate QTmax and QTmin and substraction of both into QTD. Followed by correction using the heart rate with Bazett formula QTcD.
Result: QTD prolongation of more than 100ms in patients with ACS may lead to MACE OR 1,25 IK95 0,17 ndash 2,71 . Following correction with Bazett formula, QTcD prolongation is also predictor 1,89 IK95 0,05 ndash 67,37.
Conclusion: QTD prolongation of more than 100ms or QTcD of more than 12.72ms might lead to MACE
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2018
T59198
UI - Tesis Membership  Universitas Indonesia Library
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Bahrullah Akbar
Jakarta: IPKN (Institut Pemeriksa Keuangan Negara), 2021
352.439 BAH l
Buku Teks  Universitas Indonesia Library
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Hutagalung, Errol Untung
"Periosteal osteosarkoma merupakan tumor ganas tulang yang jarang didapat, dibentuk dari sarkoma tulang dengan didominasi komponen tulang rawan yang berdiferensiasi dan tumbuh pada permukaan tulang. Penelusuran kepustakaan tidak banyak menyebutkan mengenai kasus ini. Laporan kasus ini terakhir dilaporkan oleh Klinik Mayo tahun 1999. Kami laporkan satu kasus periosteal osteosarkoma pada penderita laki-laki berusia 17 tahun. Penderita menjalani tindakan pembedahan berupa prosedur ?limb salvage?, dengan pra dan pasca bedah penderita mendapat kemoterapi (neo-ajuvan dan ajuvan). Tidak ditemukan rekurensi lokal dan metastasis di paru, pada follow up sampai dengan 14 bulan pasca bedah. (Med J Indones 2003; 12: 166-70)

Periosteal osteosarcoma is a rare type of malignant bone neoplasm, with predominantly cartilaginous component and arising on the bone surface. Reports of the case in the literature were rare. Last case was reported by Mayo Clinic in 1999. We report a case of periosteal osteosarcoma in a 17-year-old male, who was treated surgically with a limb salvage procedure, neoadjuvant and adjuvant chemotherapy were also given to the patient. There was no local recurrence and lung metastases up to 14 months after surgery. (Med J Indones 2003; 12: 166-70)"
2003
MJIN-12-3-JulSep2003-166
Artikel Jurnal  Universitas Indonesia Library
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Lubis, Andri Maruli Tua
"Penganiayaan anak merupakan masalah sosial dan masalah medis yang penting dan dapat menyebabkan kecacatan dan kematian pada anak. Angka kejadian penganiayaan anak dalam setahun diperkirakan sekitar 15 sampai 42 kasus diantara 1000 anak dan terdapat kecenderungan peningkatan. Patah tulang merupakan tanda klinis kedua terbanyak yang ditemukan setelah lesi kulit, dan sekitar sepertiga anak yang teraniaya akan mendatangi ahli bedah tulang. Kami melaporkan seorang anak laki-laki berusia 7 bulan yang diduga mengalami penganiyaan anak. Diagnosis kami didasarkan pada temuan patah tulang multiple, keterlambatan dalam mencari pertolongan medis dan perbedaan antara riwayat perjalanan penyakit dengan temuan klinis. Anak tersebut mengalami patah tulang multipel dengan proses penyembuhan yang bervariasi, termasuk patah tulang pada suprakondilar humerus kiri, radius dan ulna kiri, radius dan ulna kanan, kedua tulang femur, tibia kanan serta tibia dan fibula kiri. Pemeriksaan radiologis merupakan modalitas yang penting dalam menegakkan kemungkinan adanya penganiayaan pada anak tersebut. Anak tersebut telah mendapatkan penanganan medis, proteksi, kelompok konsultasi untuk kedua orang tua dan sedang dalam penyelidikan pihak kepolisian. (Med J Indones 2004; 13: 59-65)

Child abuse is a pervasive social and medical problem that remains a major cause of disability and death among children. The annual incidence of abuse is estimated to be 15 to 42 cases per 1,000 children and appears to be increasing. Fractures are the second most common presentation of physical abuse after skin lesions, and approximately one third of abused children will eventually be seen by an orthopedic surgeon. We report a 7-month-old boy who was suspected to be abused. Our diagnosis was based on findings of multiple fractures, delay in seeking medical treatment and discrepancy between the history of illness and the clinical findings. He sustained multiple fractures in variety of healing, namely fractures on left supracondylar humeri, left radius and ulna, right radius and ulna, both femora, right tibia, and left tibia and fibula. Radiological examination was an important modality in revealing the possibility of abuse on this child. He had received medical treatment, protection, consultation team for the parents and an underway police investigation. (Med J Indones 2004; 13: 59-65)."
2004
MJIN-13-1-JanMar2004-59
Artikel Jurnal  Universitas Indonesia Library
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Jovita Krisita
"Penyakit jantung koroner merupakan salah satu penyakit kardiovaskular yang paling umum ditemukan pada populasi pekerja dengan salah satu faktor risiko adalah jam kerja yang panjang terutama pada laki-laki. Tinjauan literatur ini bertujuan untuk mengevaluasi hubungan antara jam kerja yang panjang dan peningkatan risiko penyakit jantung koroner pada pria dewasa. Metode pencarian literatur yang digunakan adalah melalui pencarian daring sesuai dengan pedoman PRISMA di PubMed dan Scopus dari awal hingga 15 Mei 2020 dengan istilah pencarian berikut: 'pria', 'jam kerja panjang', 'lembur', dan 'risiko penyakit jantung koroner' di Medis Subject Heading Terms (MeSH Terms), judul, kata teks, abstrak, dan semua bidang. Pencarian manual dilakukan dengan mencari bagian referensi dari semua makalah yang diambil sebagai sumber potensial artikel relevan yang memiliki populasi yang tumpang tindih (n=4). Pada akhir proses pencarian literatur, sebuah artikel penelitian dipilih untuk proses penilaian kritis dan ditemukan valid dan penting bagi pasien kami. Peningkatan risiko Infark Miokard Akut sebanyak dua kali lipat ditemukan pada pria dengan jam kerja tambahan sama dengan atau lebih dari 3 jam per hari. Rekomendasi tempat kerja dapat berupa penilaian kembali bekerja, program rehabilitasi, termasuk penilaian beban kerja dan modifikasi jam kerja. Studi intervensi lanjutan diperlukan untuk mendapatkan tingkat bukti yang lebih tinggi. 

Coronary heart disease is one of the most common cardiovascular diseases in worker population and may have resulted from long working hours especially in male population. This review aims to evaluate the relationship between long working hours and increased risk of coronary heart disease in adult males. We did online search in accordance with the PRISMA guidelines in PubMed and Scopus from inception to May 15th, 2020 with the following search terms: 'male', 'long working hours', ‘overtime’, and ‘coronary heart disease risk' in Medical Subject Heading Terms (MeSH Terms), title, textword, abstracts and all fields. Manual search was done by hand-searched the reference sections of all the retrieved papers as a potential source of relevant articles that have overlapping population (n=4). At the end of searching process, one study was chosen for critical appraisal process  that is valid and substantial for our patient. We found Acute Myocardial Infraction risk in male (additional work hours equal to or more than 3 hours per day) increased twofold. Workplace reccomendations that can be made for this patient are return to work assessment, rehabilitation program, work load assessment and modified- working hours. Further intervention studies required to gain higher evidence. "
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2022
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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