Hasil Pencarian  ::  Simpan CSV :: Kembali

"Angka kematian meningitis tidak mengalami epnurunan walaupun terdapat penurunan angka kejadian meningitis dan berkembangnya penemuan antibiotik."

"Latar Belakang. Gangguan memori merupakan konsekuensi epilepsi lobus temporal (ELT) dan salah satu acuan penentuan zona epileptogenik, disesuaikan semiologi kejang, EEG iktal serta neuroimaging. Hal ini diharapkan dapat meningkatkan keberhasilan tatalaksana komprehensif termasuk terapi pembedahan dan meningkatkan kualitas hidup pasien. Tujuan. Mengetahui gambaran gangguan memori penyandang ELT di RSCM. Metode. Desain penelitian berupa studi potong lintang. Subyek adalah penyandang ELT kiri atau kanan, diperoleh secara konsekutif, kemudian dilakukan pemeriksaan Rey Auditory Verbal Learning Test (RAVLT) dan Rey Osterrieth Complex Figure Test (ROCFT) .Hasil. Diperoleh 85 subyek, 63.5% menderita gangguan memori. Dari 24 subyek gangguan memori visual, 29.6% dengan fokus kanan, dan 14.8% dari kiri. Dari 16 subyek gangguan memori auditorik, 25.9% dari fokus kiri dan 3.7% dari kanan. Gangguan memori visual dan auditorik pada 14 orang, dengan fokus kiri 11.1% dan kanan 14.8%. Fokus cetusan kanan berhubungan signifikan dengan gangguan memori visual dan kiri berhubungan signifikan dengan memori auditorik (p=0.001). Penggunaan OAE (p<0.10, OR 2.300,IK 95% 0.874,6.050) mempengaruhi gangguan memori secara umum. Lama menderita epilepsi (p<0.10;OR2.953;IK 95%0.863,10.110), penggunaan OAE (p<0.10;OR9.253;IK 95%1.355,63.168) dan fokus cetusan (p<0.10;OR 19.620; IK 95% 2.012,191,312) mempengaruhi gangguan memori auditorik. Onset bangkitan awal (p<0.10;OR 3.043,IK95%,0.110, 1.136) mempengaruhi gangguan memori visual. Lama menderita epilepsi (p<0.10;OR 2.383; IK95% 0.899,6.318) mempengaruhi gangguan memori visual dan auditorik.Kesimpulan. Sebagian besar penyandang ELT menderita gangguan memori. Gangguan memori visual atau auditorik menunjukkan efek lateralisasi yang signifikan. Penggunaan OAE, lama menderita epilepsi, usia saat bangkitan awal dan fokus cetusan dapat mempengaruhi gangguan memori.

---

Background. Memory impairment was a consequence of temporal lobe epilepsy (TLE). Memory impairment with semiology, ictal EEG and neuroimaging were used in determining the epileptogenic zone of TLE, so we could improve the comprehensive management of TLE, and improve patient?s quality of life. Objectives.To determine the proportion of memory impairment in people with TLE in RSCM. Methods A cross-sectional study, subjects were those with left or right TLE. The memory function were assessed using Rey Osterrieth Complex Fugure Test (ROCFT) and Rey Auditory Verbal Learning Test (RAVLT). Results. There were 85 eligible subjects. Memory impairment was found in 63.5% subjects. Visual memory impairment were found in 24 subjects, 29.6% with right focus and 14.8% left focus. Auditory memory impairment were found in 16 subjects, 25.9% with left focus and 3.7% right focus. Visual and auditory memory impairment were 14 people, 11.1% with left focus and 14.8% were right. The right sided focus was associated with visual memory impairment and auditory memory impairment was associated with leftfocus (p = 0.001). The use of Anti Epileptic Drugs (AED) (p <0,10; OR 2.300; 95% CI 0.874; 6.050) affected memory impairment in general. Duration of epilepsy (p <0.10; OR 2.953;95% CI 0.863;10.110) , the use of AED (p <0.10; OR 9.253; 95% CI 1.355;63.168) and focal discharges (p <0.10; OR 19,620; 95% CI 2.012;191,312) affected the auditory memory impairment. Early seizure onset (p <0.10; OR 3.043; 95% CI 0.110; 1136) affected visual memory impairment. Duration of epilepsy (p <0.10; OR 2,383; 95%CI 0.899;6.318) affected visual and auditory memory impairment. Conclusion. Most of subjects were suffering from memory impairment. Subjects with visual or auditory memory impairment showed significantly effects of lateralization. The use of AEDs, duration of epilepsy, early onset of seizure affected memory impairment."

"Latar Belakang :Event-related potensial (ERP), terutama P300, merupakan perubahan potensial otak yang menggambarkan proses pengolahan stimulus yang diterima. Pemeriksaan ERP merupakan salah satu tekhnik neurofisiologis yang non-invasive, tetapi objektif, yang sexing digunakan untuk mengevaluasi aktivitas kognitif seseorang, terutama yang berkaitan dengan atensi, persepsi memori, fungsi eksekutif, dan kontrol perilaku.Metode :Pemeriksaan ERP auditorik diskriminasi 2 nada dilakukan pada 81 anak asimptomatik yang memenuhi kriteria inklusi dari 3 sekolah dasar swasta di Jakarta. Rerata performa motorik (kecepatan reaksi, hits, dan commission error) serta iatensi dan amplitude komponen-komponen ERP (N I00, N200, dan P300) yang timbul terhadap nada target direkam dan dianalisa berdasarkan faktor usia dan jenis kelamin.Basil :Kecepatan reaksi, hits, dan latensi P300 secara statistik berbeda bermakna berdasarkan faktor usia. Terdapat korelasi negatif dengan kekuatan sedang antara faktor umur dan kecepatan reaksi dan latensi P300 (p<0.0l). Sedangkan faktor usia dan hits berkorelasi secara positif dengan kekuatan sedang. Tidal( didapatkan perbedaan yang bermakna secara statistik antara performa motorik maupun latensi dan amplitudo P300 terhadap faktor jenis kelamin.Kesimpulan :Perkembangan fungsi kognitif anak tampaknya berkaitan dengan maturasi otak sejalan dengan pertambahan usia, dan tidak berkaitan dengan faktor jenis kelamin. Perneriksaan ERP auditorik diskriminasi 2 nada dapat digunakan untuk menilai perkembangan fungsi kognitif anak.

---

Background :

Event Related Potentials (ERPs), especially P300, are electrical changes generated in the brain in association with stimuli processing. They can provide a non-invasive but objective means to evaluate the activity of human brain associated with attention, perception, memory, decision making, and control of behavior.

Methods:

Auditory ERP two-tone discrimination (`oddball ) paradigm was presented to 81 healthy asymtomatic school aged children of three private elementary schools in Jakarta. Motor performances (reaction time, hits, and commission error) and latency and amptlitude of ERP components (N100, N200, and P300) elicited to target stimuli were recorded and analyzed for between group difference (age and sex).

Results:

Reaction times, hits, and P300 latency were significantly different between age groups (pcO.01). There were also moderately negative correlation between age groups and reaction limes and P300 latencies (p<0.01). Moderately positive correlation were noted between hits and age (p <0 01). None of motor performances nor latencies and amplitudes of P300 were different between sex groups (p>0.05).

Conclusions:

Maturation of cognitive brain functions in children are related to age development despite of sex gender. Auditory ERP two-tone discrimination ERPs are excellent tools for the study of cognitive brain functions in humans and the developmental time course of these functions in childhood."

"Angka kematian meningitis tidak mengalami penurunan walaupun terdapat penurunan angka kejadian meningitis dan berkembangnya penemuan antibiotik baru. Tujuan penelitian ini adalah melaporkan pola kematian meningitis dan niengetahui faktor yang berhubungan dengan kematian akibat meningitis pada penderita yang dirawat. Penelitian potong lintang menggunakan data rekam medis penderita meningitis yang dirawat di bangsal Neurologi RS Cipto Mangunkusumo Jakarta dari Januari 1997 - Desember 2005. Data dilaporkan dalam bentuk tekstular dan table, dan kemudian dilakukan analisis mcnggunakan Chi-kuadrat untuk data kategorik dan Student's "t" rest untnk data numerical. Analisis menggunakan program SPSS v 13 for Windows. Penelitian ini mengikutsertakan 273 penderita, yang terdiri dari 81 wanila dan 192 pria, dengan usia antara 12 sampai 78 tahun. Seratuis empat belas penderita meninggal dan 159 hidup. Penurunan kesadaran, terutama sopor (OR 10.44, p 0.000) dun koma (OR 53.333, p 0.000), dan adanya himaparesis (OR 2.068, p 0.009) berhubungan dengan keluaran. Angka kematian meningitis masih tinggi (41.8%). Dari penelitian ini didapatkan tingkat kesadaran dan heiniparesis berhubungan dengan angka kematian. (Med J Indones 2006; 15:236-41).

---

Mortality rate of meningitis is not decreased even though there is decreasing meningitis rate and advanced development of antibiotics. The purpose of this study is to find out meningitis mortality pattern and to evaluate factors related to meningitis mortality in hospitalized patients. Study was done using retrospective data from medical records of the patients administered in llte Neurology ward of Cipto Mangunkusumo hospital from January 1997 - December 2005. Data were reported descriptively in text* and tables, and analyzed with Chi-square for categorical data and Student's "t" test for numerical data, then for final model using multinomial logistic regression analysis. Two hundred and seventy three patients were included in this study, consisted of 81 female patients and 192 male patients age between 12 to 78 years old. A hundred and fourteen patients died during am! 159 patients lived. Decreased level of consciousness, especially stupor (OR 10.44, p 0.000) and coma (OR 53.333, p 0.000), and presence of motor weakness (OR 2.068, p 0.009) had relationship with outcome. Mortality rate of meningitis is still high (41.8%) because there are some factors that affect its prognosis. From this study, onset, level of consciousness, and motor weakness are predictors for meningitis death. (Med J Indones 2006; 15:236-41)."

"From neurology to methodology and back offers a translational study of neurology and technology from both sides. The fundamental topics covered range from basic concepts such as sampling and simple statistical measures via Fourier analysis to source localization. Providing clinically relevant context and introduce technical concepts, the neurological diseases presented range from epilepsy, brain tumors and cerebrovascular diseases to tremor, MS and neuromuscular diseases. All topics are presented in a true clinical neuroengineering approach.Each chapter begins with one or more patient cases for inspiration. Each case is then presented to illustrate a working example of a distinct neurodiagnostic technique, and the mathematical and physical principles underlying these techniques are explained. Finally, the author returns to the patient, and examines how the presented technology can help provide a diagnosis for each case."