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"Dalam kurun waktu Juni 2003 sampai dengan Juni 2004, pasien-pasien yang menderita adenomiosis berdasarkan ultrasonografi transvaginal dan memiliki keluhan menorhagia, dismenore, mcmpun nyeri pelvis diikulsertakan dalam penelitian. Randomisasi dilakukan untuk mengalokasikan subjek ke dalam kelompok reseksi dan kelompok miolisis. Semua pasien dan kedua kelompok mendapal GnRH analog 3 siklus pasca-laparnskopi operatif. Penilaian dilakukan dalam jangka waktu 6 bulan, baik secara subjektif melalui kuesioner maupun secara objektif melalui evaluasi volume adenomiosis per ultrasonografi transvaginal di akhir semester. Terdapat 20 pasien yang menjalani pembedahan, 10 dalam kelompok reseksi dan JO dalam kelompok miolisis. Komplikasi bermakna tidak ditemukan pada kedua kelompok. Evaluasi subyektif dapat dilakukun pada semua pasien sedangkan evaluasi objektif hanya dapal dilakukan pada 17pasien. Tidak didapatkan perbedaan bermakna antar-kelompok dalam penentuan skor keluhan menorhagia (p = 0.399) dan dismenorea (p=0.213). Tidak ditemukan perbedaan bermakna dalam median penambahan volume adenomiosis (p = 0.630) antara kelompok reseksi (medicui= +15,35% (-100 - 159)) dengan kelompok miolisis (median=+48,43% (-100 - 553)). Lima pasien hamil, 3 dari kelompok reseksi, 2 dari kelompok miolisis, dengan satu kasus ruptur uteri pada usia kehamilan 8 bulan pada kelompok miolisis. Efektifitas reseksi adenomiosis per laparoskopi tidak berbeda bermakna dengan miolisis adenomiosis per laparoskopi dalam penataksanaan adenomiosis bergejala. Miolisis tidak disarankan bagi wanitayang masih ingin hamil. (Med J Indones 2006; 15:9-17).

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Effective therapy preserving reproductive function in adenomyosis is warranted. From June 2003 to June 2004, patients diagnosed as having adenomyosis by transvuginal ultrasound and had symptoms of menorrhagta, dysmenorrhea, and pelvic pain were randomly allocated to either receive laparoscopic resection or myolysis. GnRH analog was given for 3 cycles after surgery. Within 6 months, symptoms were evaluated using questionnaires and at the end of follow up, adenomyosis volume was assessed by transvaginal ultrasound. There were 20 patients included, 10 patients had resection and the rest underwent myolysis. Both procedures did not yield significant complications. Subjective evaluation by questionnaires was done in all patients. Three patients could not be evaluated objectively by transvaginal ultrasound, 2 patients resigned and I was pregnant. There was no significant difference in menorrhagia and dysmenorrhea reduction score between the 2 groups (p=0.399 and 0.213, respectively). In both groups, dysmenorrhea was reduced significantly after treatment. No significant statistical difference was found in median adenomyosis volume increment (p=0.630) between the resection (median= + !5.35% (-100-159)) and myolysis groups (median=+48.43% (-100-553)). Five patients were pregnant, 3 from the resection group and 2 from the myolysis group. Uterine rupture was found in I patient (from the myolysis group) at the age of 8 months of pregnancy. The effectiveness of laparoscopic adenomyosis resection was not significantly different compared with la-parascopic myolysis as an alternative conservative surgery in treating symptomatic adenomyosis. Myolysis was not recommended for women who wish to be pregnant. (MedJ Indones 2006; 15:9-17)"

"[Ureteropelvic junction obstruction (UPJO) merupakan salah satu kelainan kongenital traktus urinarius dengan insidensi 5/100.000 per tahun. Tindakan bedah yang minimal invasif dapat memberikan waktu operasi yang lebih singkat, morbiditas minimal, penurunan kebutuhan analgesia pascaoperasi, waktu rawat yang lebih singkat, dan penyembuhan yang lebih cepat daripada operasi terbuka. Meskipun demikian, tatalaksana optimal ureteropelvic junction obstruction masih dalam perdebatan. Banyak studi yang membandingkan endopielotomi dan pieloplasti per laparoskopi. Angka kesuksesan endopielotomi dan pieloplasti dilaporkan bervariasi dalam berbagai studi.TujuanUntuk mengidentifikasi tatalaksana optimal dari ureteropelvic junction obstruction.MetodeMeta-analisis dari studi kohor yang dipublikasi sebelum Februari 2014 dilakukan dengan menggunakan data Medline. Kriteria inklusi adalah tatalaksana ureteropelvic junction obstruction dengan endopielolitotomi (antegrad dan atau retrograd) dan pieloplasti per laparoskopi (transperitoneal atau retroperitoneal). Kriteria eksklusi adalah perbaikan UPJO sekunder dan fungsi ginjal yang buruk. Kriteria sukses didefinisikan sebagai tidak adanya gejala klinis dan dikombinasikan dengan penurunan hidronefrosis secara signifikan yang ditunjukkan dengan diuretic IVU atau ultrasonografi dan tidak ada tanda obstruksi pada diuretic IVU atau renografi diuretik atau tes Whitaker. Random-effect model dengan metode DerSirmonian-Laird digunakan untuk menghitung risk ratio (RR) dan 95% interval kepercayaan (IK) gabungan. Heterogenitas dinilai dengan menggunakan statistik I2. Semua analisis dilakukan dengan menggunakan Stata statistical software, versi 12.0 (StataCorp).HasilKami menganalisa 4 studi kohor. Angka kesuksesan dari 479 pasien (233 pieloplasti per laparoskopi, 246 endopielotomi), 21 bulan pascaoperasi, adalah 92.3% (215/233) setelah pieloplasti per laparoskopi, 63.8% (157/246) setelah endopielotomi. Berdasarkan angka keberhasilan tatalaksana UPJO, pieloplasti lebih baik daripada endopielotomi (risk ratio keseluruhan adalah 1.35 (95% CI 0.97 hingga 1.88); p<0.0001 dan I2=90.6 %).KesimpulanPieloplasti per laparoskopi memiliki angka keberhasilan yang lebih tinggi daripada endopielotomi. Metaanalisis ini dapat membantu ahli urologi sebelum memulai tindakan terapi UPJO., The ureteropelvic junction obstruction (UPJO) is one of the most common congenital abnormalities of the urinary tract with a reported incidence of 5/100,000 annually. Minimal invasive surgeries have emerged giving short operative time, minimal morbidity, decreased postoperative analgesic requirements, shorter hospitalization, and early recovery and convalescence compared to open surgery. Yet, the optimal management of ureteropelvic junction obstruction is still in debate. Many studies have been conducted comparing endopyelotomy and laparoscopic pyeloplasty. The success rates of endopyelotomy and pyeloplasty are reported in various success rate in many studies.ObjectiveTo identify the optimal management of ureteropelvic junction obstruction .MethodA meta-analysis of cohort study published before February 2014 was performed using Medline databases. Management of ureteropelvic junction obstruction treatment using endopyelolitotomy (anterograde and or retrograde) and laparoscopic pyeloplasty (transperitoneal or retroperitoneal) were included. Publication using secondary UPJO repair, poor functioning kidney were excluded. Success was defined as absence of any clinical symptoms and combined with significant reduction of hydronephrosis showed with on diuretic IVU or ultrasonography result, and no sign of obstruction on diuretic IVU or diuretic renography or Whitaker test. A random-effects model with DerSirmonian-Laird method was used to calculate the pooled Risk Ratio (RRs) and 95% Confidence Interval (CI). We assessed the heterogeneity by calculating the I2 statistic. All analyses were performed with Stata statistical software, version 12.0 (StataCorp).Result We analized 4 cohort studies. The success rate from 479 patients (233 laparoscopic pyeloplasty, 246 endopyelotomy), 21 months postoperatively, was 92.3% (215/233) after laparoscopic pyeloplasty, 63.8% (157/246) after endopyelotomy. Based on success rate in ureteropelvic junction obstruction management, laparoscopic pyeloplasty is better than endopyelotomy (overall risk ratio was 1.35 (95% CI 0.97 to 1.88); p<0.0001 and I2=90.6 %).]"

"ABSTRACTPurposeTo compare the time-course change in the postoperative anorectal function between laparoscopic intersphincteric resection (ISR) and low anterior resection (LAR).MethodsThis is a single-institution observational study. We evaluated the time-course change in the anorectal function using functional questionnaires before and at 6, 12, and 24 months after laparoscopic ISR or LAR.ResultsSixty-two patients answered the functional questionnaires (28 in the ISR group and 34 in the LAR group). In the ISR group, the Wexner scores at 6, 12, and 24 months postoperatively were significantly higher than preoperatively. Importantly, the Wexner score at 24 months postoperatively was significantly lower than that at 6 months postoperatively. The low GIFO scores at 6 and 12 months postoperatively tended to be recovered to some extent at 24 months postoperatively. In the LAR group, Wexner score at 6 months postoperatively was significantly higher than that preoperatively. Notably, the Wexner score at 12 months postoperatively was recovered to almost the same as that preoperatively. The GIFO scores at 12 months postoperatively were mostly recovered to the same levels as those preoperatively.ConclusionsLaparoscopic ISR exhibits different time-course changes in the anorectal function from laparoscopic LAR."

"Tujuan tulisan ini adalah mendiskusikan tatalaksana teknisi pengobatan endometriosis, dengan penekanan pada peran laparoskopi operatif dan pengobatan medikamatosa"

"Tujuan tulisan ini adalah mendiskusikan tatalaksana terkini pengobatan endometriosis dengan penekanan pada peran laparoskopi operatif dan pengobatan medikamatosa. Ketepatan mendiagnosis endometriosis tanpa Laparoskopi sangat lemah, dengan positif palsu 44 % dan negatif palsu 19 %. Tersangka endometriosis yang didiagnosis tanpa laparoskopi akan ditemukan 81 % secara laparoskopi, sisanya 19 % bukan endometriosis. Disimpulkan bahwa laparoskopi sangat dibutuhkan untitk mendiagnosis dan mengobati endometriosis. Pengobalun medikamentosa efektifdalam hal merendahkan progresifitas endometriosis. (MedJ Indones 2006; 15:121-4)

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The objective of this paper is to discuss the current guidelines for treatment of endometriosis, emphasis on the role of laparoscopic surgery and medical treatment. The accuracy of diagnosis ofendometriosis without laparoscopy is very low, as a false negative rate of 19 % and a false positive rate of 44 %, when a diagnosis was made pre iaparoscopy, 81 % had the diagnosis can confirmed on laparoscopy, while 19 % did not have endometriosis. It is concluded that laparoscopy is required for evaluation ami treatment of endometriosis. Medical therapy is effective in reducing progression of endometriosis score. (MedJ Indones 2006; 15:121-4)"

"Tulisan ini membahas dan melaporkan ruptura uteri saat kehamilan dan persalinan pada kasus pasca miomektomi perlaparoskopi. Laporan kasus kejadian ruptur uterus pada pasien yang sebelumnya mengalami laparoskopi operatif miomektomi miom intramural Æ 3.5 cm, yang 6 bulan kemudian mengalami kehamilan. Tidak ada gejala ke arah ruptura uteri saat kehamilan namun pada saat usia gestasi 34 minggu, pasien mengalami gejala ruptura uteri. Pada saat laparotomi; ditemukan fetus 2100 gram mati, dan robekan jaringan 5 cm pada sikatriks bekas miomektomi. Pada pasien yang mengalami miomektomi per laparoskopi khususnya miom intramural mempunyai risiko ruptura uteri pada saat persalinan. (Med J Indones 2004; 14: 113-6)

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Following laparoscopic myomectomy, uterine rupture during pregnancy or delivery in the area of the scar is a very rare but dangerous complication. Individual cases of uterine rupture during pregnancy are described in the literature. Case report of uterine rupture during delivery in a patient who had previously undergone laparoscopic myomectomy. In the case presented here, the patient conceived 6 months after an 3.5 cm intramural myoma, had been laparoscopically removed. No symptoms suggesting uterine rupture were observed during the pregnancy, but in the first stage of delivery the condition of the patient deteriorated and symptoms of oligaemic shock developed. A laparotomy was performed, which showed the presence of 2100 gr fresh dead fetus in the abdominal cavity and ruptured uterine muscle in the scarred area about 5 cm. In patients who have previously undergone a laparoscopic myomectomy, there is some risk of uterine rupture at delivery. This is also the case where unappropriate suturing of the uterine muscle had been required. (Med J Indones 2004; 14: 113-6)"

"ABSTRACTLow anterior resection syndrome (LARS) commonly develops after an anal sphincter-preserving operation (SPO). The etiology of LARS is not well understood, as the anatomical components and physiological function of normal defecation, which may be damaged during the SPO, are not well established. SPOs may damage components of the anal canal (such as the internal anal sphincter, longitudinal conjoint muscle, or hiatal ligament), either mechanically or via injury to the nerves that supply these organs. The function of the rectum is substantially impaired by resection of the rectum, division of the rectococcygeus muscle, and/or injury of the nervous supply. When the remnant rectum is small and does not function properly, an important functional role may be played by the neorectum, which is usually constructed from the left side of the colon. Hypermotility of the remnant colon may affect the manifestation of urge fecal incontinence. To develop an SPO that minimizes the risk of LARS, the anatomy and physiology of the structures involved in normal defecation need to be understood better. LARS is managed similarly to fecal incontinence. In particular, management should focus on reducing colonic motility when urge fecal incontinence is the dominant symptom."