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Soesilowati S.R.
"Diabetic neuropathy is a complication of diabetes mellitus that is often overlooked, since there are often no subjective complaints during initial stages, and sensory deficit is often only found after objective examination.
Diabetic neuropathy is defined by the San Antonio Concensus of 1988 as "clinical or subclinical neural disturbance that occurs in diabetes mellitus, with no signs of other peripheral neuropathy. Neuropathy may manifest on the somatic, peripheral, as well as autonomicic nervous systems."
The incidence rate of diabetic neuropathy is reported to be 10-90%. Such high variation is due to differences in the diagnostic criteria or method to establish the diagnosis.
Reports of peripheral neuropathy from various hospitals in Indonesia are as follows: Cipto Mangunkusumo Hospital / Jakarta (1989) 68.16%, Hasan Sadikin Hospital (1989) 12.2%, Dr. Sutomo Hospital / Surabaya (1990) 52.21%, Dr. Pirngadi Hospital / Medan (1996) 18.05%, Dr. Wahidin Sudirohusodo Hospital / Ujung Pandang (1997) 57.81%. Asril Bahar, Jakarta (1985), reported an incidence rate for parasympathetic autonomicic neuropathy of 11.9%, while Harsinen Sanusi, Ujung Pandang (1989) reported an incidence rate of 66.7%.
"
2003
AMIN-XXXV-1-JanMarc2003-27
Artikel Jurnal  Universitas Indonesia Library
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Taufik Rizkian Asir
"Latar belakang: Diabetes melitus merupakan faktor risiko penting terjadinya
aterosklerosis, aterosklerosis merupakan penyakit sistemik yang bisa terjadi di seluruh
pembuluh darah baik pada mikrovaskular maupun makrovaskular. Adanya bukti
iskemia akibat stenosis yang disebabkan aterosklerosis pada salah satu pembuluh darah,
mengharuskan kita lebih waspada akan adanya proses aterosklerosis di tempat lain.
NPD di kaki terjadi akibat komplikasi diabetes pada mikrovaskular yang akhirnya
mengakibatkan kerusakan pada persarafan di kaki. Maka perlu mewaspadai proses
ateroslerosis di tempat lain, baik pada pembuluh arteri makro maupun mikrovaskular di
kaki. Pemeriksaan non invasif untuk melihat adanya ganguan makrovaskular di kaki
menggunakan ABI dan TBI sedangkan untuk gangguan mikrovaskular dengan TcPO2.
Penelitian ini dilakukan untuk dapat menilai hubungan derajat neuropati perifer diabetik
yang dinilai dengan TCSS dengan proses ateroskerosis dipembuluh darah kaki, baik
yang makrovaskular dengan ABI dan TBI maupun mikrovaskular TcPo2 pada pasien
DM tipe 2.
Metode: Penelitian potong lintang dilakukan pada pasien DM tipe 2 dengan NPD
dengan nilai TCSS >5 di Poliklinik Pelayanan Jantung Terpadu, poliklinik Endokrin
dan Metabolik dan Poliklinik Ilmu Penyakit Dalam Umum RSCM. Data diperoleh dari
wawancara, rekam medik, pemeriksaan ABI, TBI dan TcPO2. Variabel penelitian
berupa derajat neuropati perifer, ABI, TBI dan TcPO2. Analisis bivariat terhadap
masing-masing variable dengan menggunakan uji Spearman.
Hasil: Sebanyak 36 subjek yang memenuhi kriteria pemilihan diikutkan dalam
penelitian, rerata usia 62 tahun dengan 20 (55,6%) di antaranya perempuan dan median
lama diabetes 12 tahun. Berdasarkan analisa bivariat dengan uji spearman penelitian ini
mendapatkan korelasi negatif yang bermakna secara statistik dengan koefisien korelasi
sedang antara derajat neuropati perifer diabetik yang dinilai dengan TCSS dengan ABI
(r = -0,475, p = 0,003) dan TBI (r = -0,421, p = 0,010). Dan pada pemeriksaan TcPO2
juga di dapatkan korelasi negatif yang bermakna secara statistik dengan koefisien
korelasi sedang ( r = -0,399, p = 0,016)
Simpulan : Terdapat korelasi negatif yang bermaksa secara statistik antara derajat
neuropati perifer diabetik dengan ABI, TBI dan TcPO2.

Background: Diabetes mellitus is important risk factor of atherosclerosis.
Atherosclerosis is systemic disease that can occur in all blood vessels both
microvascular and macrovascular. There is evidence of ischemia due to stenosis caused
by atherosclerosis in one blood vessel, which requires us to be more aware with the
process of atherosclerosis in other places. Diabetic peripheral neuropathy (DPN) in the
lower extremity results from complications of diabetes in the microvascular which can
damage nerve in the lower extremity. Then it is necessary to be aware of the process of
aterosclerosis elsewhere, both in the macro and microvascular arteries in the lower
extremity. Non-invasive examination to look macrovascular disorders in the lower
extremity are using ankle brachial index (ABI) and toe brachial index (TBI) while for
microvascular disorders with TcPO2. This study was conducted to assess the
association of the degree of diabetic peripheral neuropathy assessed by toronto clinical
scoring system (TCSS) with the process of atherosclerosis in the blood vessels of the
lower extremity, both macrovascular with ABI and TBI as well as microvascular TcPo2
in Patients with type 2 diabetes mellitus (DM)
Methods: Cross-sectional study was carried out in patients with type 2 DM with DPN
with TCSS values> 5 in the Integrated Cardiac Polyclinic, Endocrine and Metabolic
Polyclinic, and Internal Medicine Polyclinics at RSCM. The Data were obtained from
interviews, medical records, ABI, TBI and TcPO2 examinations. The research variables
are the degree of peripheral neuropathy, ABI, TBI and TcPO2. Bivariate analysis of
each variable was used the Spearman test.
Results: Total of 36 subjects who met the selection criteria were included in the study,
the average age was 62 years with 20 (55.6%) of whom were women and the median
duration of diabetes was 12 years. Based on bivariate analysis with the Spearman test,
this study found a statistically significant negative correlation with moderate correlation
coefficient between the degree of diabetic peripheral neuropathy assessed by TCSS with
ABI (r = -0.475, p = 0.003) and TBI (r = -0.421, p = 0.010) . The TcPO2 examination
also found a statistically significant negative correlation with moderate correlation
coefficient (r = -0.399, p = 0.016)
Conclusion : There is a statistically significant negative correlation between the degree of diabetic peripheral neuropathy with ABI, TBI and TcPO2 examinations.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Nurul Fadli
"Pendahuluan: Neuropati diabetik merupakan komplikasi diabetes yang paling sering ditemukan dalam praktik sehari-hari. Gejala terutama dikeluhkan rasa nyeri atau baal pada kedua tungkai. Penyakit arteri perifer (PAP) juga merupakan komplikasi diabetes dengan manifestasi nyeri pada tungkai. Adanya neuropati dan PAP akan mempengaruhi gejala satu sama lain sehingga umumnya pasien akan datang dalam keadaan yang lebih berat. Penelitian ini bertujuan untuk mengetahui gambaran klinis dan hasil pemeriksaan elektrodiagnostik neuropati diabetik dengan atau tanpa PAP.
Metode: Studi ini bersifat deskriptif dengan metode potong lintang pada pasien diabetes melitus tipe 2 dengan neuropati berdasarakan Toronto clinical neuropathy score (TCNS). Pasien kemudian dilakukan pemeriksaan elektrofisiologi (Kecepatan hantar saraf (KHS) dan sympathetic skin response (SSR)) untuk membuktikan adanya neuropati serta pemeriksaan ankle brachial index (ABI) dan toe brachial index (TBI) untuk mendiagnosis adanya PAP.
Hasil: Sebanyak 46 subjek penelitian yang terdiri dari 22 laki-laki dan 24 perempuan. Rerata usia subjek penelitian adalah 63,09 (±9,98) tahun dengan rerata lama menderita diabetes 13,57 (±10,43) tahun. Kebanyakan pasien memiliki kontrol glikemik yang kurang baik dengan median HbA1C of 7,35 (min-max: 5,6-12,2). Didapatkan sebanyak 22 orang terdiagnosis PAP berdasarkan pemeriksaan TBI. Berdasarkan analisis bivariat didapatkan kemaknaan secara statistik antara adanya keluhan nyeri, rasa kram, lokasi nyeri, klaudikasio intermiten serta riwayat penyakit jantung koroner dengan adanya PAP (masing-masing p < 0,05).
Kesimpulan: Adanya keluhan nyeri, rasa kram, lokasi nyeri, klaudikasio intermiten, serta riwayat penyakit jantung koroner dapat menunjukkan adanya kemungkinan PAP pada pasien neuropati diabetik.
Kata kunci: neuropati diabetik, penyakit arteri perifer, kecepatan hantar saraf, respon kulit simpatetik

Background: Diabetic neuropathy (DN) is a common complication of diabetes. Symptoms can be tingling, pain or numbness in the leg.(1) Peripheral arterial disease (PAD) is also a complication of diabetes which can cause pain in the leg. The presence of DN and PAD affect each other, resulting in worse patient condition. The aim of this study to evaluate clinical characteristics and electrodiagnostic findings in diabetic neuropathy with and without PAD.
Method: a descriptive cross-sectional study in type 2 diabetes mellitus patient with neuropathy based on Toronto clinical neuropathy score (TCNS). Patients were evaluated with electrodiagnostic study (nerve conduction study (NCS) and sympathetic skin response (SSR)) to confirm neuropathy and also ankle brachial index (ABI) and toe brachial index (TBI) to evaluate PAD.
Results: a total of 46 subjects consisted of 22 male and 24 females include in this study. The mean age of the study population was 63,09 years (±9,98). The mean duration of diabetes in the study population was 13,57 years (±10,43). Most of the patients had poorly controlled diabetes with a median HbA1C of 7,35 (min-max: 5,6-12,2). Ten patients have PAD based on TBI examination. From bivariate analysis, there is statistically significant association between pain, cramp, pain location, intermittent claudication, and history of coronary arterial disease with the presence of PAD (p < 0,05).
Kesimpulan: The presence of pain, cramp, pain location, intermittent claudication, and history of coronary arterial disease can predict the presence of PAD in DN patients.
Keywords: diabetic neuropathy, peripheral arterial disease, nerve conduction study, sympathetic skin response"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Dian Anggraini
"ABSTRAK
Deformitas kaki dapat menyebabkan perubahan mobilitas sendi, luas kontak kaki ke permukaan, kemampuan neuromuskular untuk menstabilkan kaki serta mempertahankan posisi berdiri tegak. Perubahan ini akan berdampak pada penurunan fungsi ekstremitas bawah. Tujuan dari penelitian ini adalah untuk mengatahui hubungan deformitas kaki dengan fungsi ekstremitas bawah pada pasien neuropati diabetik. Desain penelitian ini adalah penelitian kuantitatif dengan pendekatan studi cross-sectional dengan jumlah sampel 105 orang responden yang mengalami neuropati diabetik dengan deformitas kaki. Analisis data menggunakan Chi Square, Anova, dan regresi logistik etiologik. Hasil penelitian menunjukkan adanya hubungan antara deformitas kaki dengan fungsi ekstremitas bawah p = 0,000, OR = 10,857 . Penelitian ini diharapkan dapat dijadikan acuan bagi perawat dalam melakukan pengkajian keperawatan untuk memprediksi penurunan fungsi ekstremitas bawah pada pasien neuropati diabetik dengan deformitas kaki sehingga bisa mencegah terjadinya resiko cedera atau jatuh pada pasien.

ABSTRACT
Foot deformity can cause various of changes in joint mobility, extent of foot contact to the surface, neuromuscular ability to stabilize the legs and maintain an upright standing position. These changes will have an impact on lower limb function. The purpose of this study was to determine the correlation of foot deformities with the lower extremity functions in diabetic neuropathy patients. The design of this study was a quantitative research with a cross sectional study approach with sample size of 105 respondents who has foot deformity with diabetic neuropathy. Data were analysed using a Chi Square, Anova, and etiologic logistic regression. The results showed a significant correlation between foot deformities with lower extremity function p 0,000, OR 10,857 . This study is expected to be used as a reference for nurses in conducting nursing assessments to predict lower extremity function in diabetic neuropathy patients with foot deformities in order to prevent the risk of injuries or falls in patients."
2017
T48515
UI - Tesis Membership  Universitas Indonesia Library
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West Sussex: John Wiley & Sons, 2003
R 616.462 ATL
Buku Referensi  Universitas Indonesia Library
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Rini Sulastiwaty
"ABSTRAK
Tujuan
Untuk membandingkan efektivitas intravitreal triamcinolone acetonide (IVTA) dan
Bevacizumab (IVB) dalam mengurangi ketebalan makula sentral (CMT) pada edema
makular diabetik (EMD) tipe kistoid dan difus
Metode
Studi ini adalah sebuah uji klinis acak tersamar tunggal. Sebanyak 24 subyek (28
mata) dengan non-proliferatif diabetic retinopathy (NPDR) yang belum pernah
menerima terapi apapun sebelumnya akan dibagi menjadi 2 kelompok berdasarkan
gambaran OCT, yaitu tipe difus dan kistoid. Subyek dalam setiap kelompok akan
diacak untuk menerima IVTA atau IVB. Evaluasi akan dilakukan pada 1 hari, 1
minggu dan 2 minggu setelah injeksi. Penilaian perubahan ketebalan makula sentral
(KMS) akan dinilai dengan Optical Coherence Tomography (OCT) lagi pada minggu
pertama dan minggu kedua.
Hasil
Penurunan KMS kelompok kistoid setelah injeksi IVTA dan IVB berbeda secara
signifikan dengan p <0,05 pada 1 minggu setelah injeksi (256,14 ± 146.58 vs 20.00 ±
110,00) dan juga 2 minggu setelah injeksi (294,86 ± 154,93 vs 98,71 ± 124,44). Pada
tipe difus, penurunan KMS setelah injeksi IVTA atau IVB tidak berbeda secara
statistik (p> 0,05), namun penurunan tersebut secara klinis kami nilai signifikan
berdasarkan hasil OCT (KMS 1 minggu setelah injeksi adalah 111,57 ± 49,72 vs
32,43 ± 37,23 dan 2 minggu setelah injeksi 135,86 ± 68.42 vs 31.86 ± 35.96)
Kesimpulan
Injeksi intravitreal triamcinolone acetonide merupakan terapi yang lebih tepat untuk
edema makula diabetik tipe kistoid

ABSTRACT
Objectives
To compare the effectiveness of intravitreal Triamcinolone Acetonide (IVTA) and
Bevacizumab (IVB) in reducing central macular thickness (CMT) of diffuse type and
cystoid type diabetic macular edema (DME)
Methods
This is a prospective, single blind, randomized clinical trial. A total of 24 subjects (28
eyes) with non-proliferative diabetic retinopathy who had never received any prior
therapy, was divided into 2 groups based on the description of the Optical Coherence
Tomography (OCT) to differentiate the type of diffuse and cystoid. Subjects in each
group were randomized to receive IVTA or IVB. Follow up was conducted at day 1,
week 1 and week 2 after injection. CMT were reassesed with OCT on follow up week
1 and week 2.
Result
CMT decrease in the cystoid group after IVTA and IVB were significantly different
with p<0.05 (256.14±146.58 vs 20.00±110.00) and also week 2 (294.86±154.93 vs
98.71±124.44). There were no different statistically (p>0.05 ) in CMT decrease
between IVTA and IVB, but the decrease were still clinically significant in our OCT
findings (in week 1 CMT were 111.57±49.72 vs 32.43±37.23 and in week 2 were
135.86 ±68.42 vs 31.86±35.96)
Conclusion
Intravitreal injection of triamcinolone acetonide is more proper therapy for cystoid
type diabetic macular edema."
Fakultas Kedokteran Universitas Indonesia, 2013
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Ahmad Affandi
"Diabetes melitus merupakan penyakit kronik dengan tingkat morbiditas dan mortalitas yang tinggi. Salah satu komplikasi yang ditakuti adalah kaki diabetik. Berdasarkan data di RSCM pada tahun 2011 sebanyak 1,3% dari pasien kaki diabetik harus menjalani amputasi. Borkosky dkk (2013) menunjukkan tingginya insidens re-amputasi pada pasien kaki diabetik sebesar 19,8%. Amputasi berulang membutuhkan biaya pengobatan yang tidak murah, selain itu dapat meningkatkan morbiditas dan mortalitas pasien. Oleh karena itu diperlukan suatu penelitian untuk mengetahui faktor-faktor risiko terjadinya re-amputasi pada pasien kaki diabetik.
Penelitian ini adalah deskriptif analitik, didapatkan adanya kecenderungan penurunan jumlah kasus amputasi kaki diabetik di RSCM dari tahun 2009-2015. Level amputasi terbanyak yang dilakukan pada pasien kaki diabetik adalah amputasi minor pada level Ray. Trauma, neuropati perifer, nilai ABI ≤0,9, dan kadar HbA1c ≥7% merupakan faktor risiko terjadinya re-amputasi pada pasien kaki diabetik. trauma merupakan faktor risiko terbesar terjadinya reamputasi pada pasien kaki diabetik (p=0,000; OR 73,842; 95%CI 19,236-283,457). Jika semua faktor risiko tersebut dimiliki oleh pasien maka risiko kumulatif untuk dilakukan re-amputasi sebesar 100%.

Diabetic mellitus is one of chronic diseases with high morbidity and mortality. One of complications of diabetic mellitus is foot diabetic. Based on data in Cipto Mangunkusumo General hospital, in 2011, prevalence of amputation for foot diabetic patients was 1,3%. Borkosky et al (2013) showed high incidence of reamputation among foot diabetic patients 19,8%. Re-amputation is highly cost and can increase morbidity and mortality in diabetic patients. Thus research needs to be done to find out risk factors of re-amputation among foot diabetic patients.
This research showed that foot diabetic amputation cases in RSCM had been decreased from 2009-2015. The most common amputation level was Ray amputation. Foot trauma, peripheral neuropathy, ABI score ≤0,9 and HbA1c level ≥7% are risk factors for re-amputation in foot diabetic patients. Foot trauma was the biggest risk factor for re-amputation in foot diabetic patients (p=0,000; OR 73,842; 95% CI 19,236-283,457). The cummulative risk factor for re-amputation for those who have all the risk factors is 100%.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2016
T-Pdf
UI - Tesis Membership  Universitas Indonesia Library
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Suyanto
"[ABSTRAK
Penderita neuropati perifer diabetik yang mengalami penurunan sensasi kaki dapat
berakibat terjadinya luka diabetik. Penelitian ini bertujuan mengetahui efektivitas
kombinasi senam kaki diabetik dan terapi SPA terhadap peningkatan sensasi kaki
pada pasien dengan neuropati perifer diabetik. Penelitian ini menggunakan kuasi
experimental pretest-posttest design with control group dengan jumlah sample 35
orang yang didapat dengan tehnik purposive sampling. Pengukuran sensasi kaki
dilakukan pada hari pertama minggu ke-1 dan hari terakhir minggu ke-4 perlakuan.
Sampel penelitian yaitu pasien neuropati perifer diabetik dengan skor sensasi kaki
maksimal 8. Hasil uji mann whitney menunjukkan ada perbedaan rerata
peningkatan sensasi kaki yang diberikan kombinasi senam kaki diabetik dan terapi
SPA dibandingkan hanya diberikan tindakan senam kaki diabetik (p value < 0.05).
Tindakan kombinasi senam kaki diabetik dan terapi SPA lebih efektif dalam
meningkatkan sensasi kaki yang akan berpengaruh terhadap menurunnya resiko
luka pada pasien DM.

ABSTRACT
Diabetic peripheral neuropathy patients with decreasing in foot sensation will
impact on diabetic ulcers. This study aims to explore the effect of combination
between diabetic legs exercise and SPA therapy on foot sensitivity escalation
among patients with diabetic peripheral neuropathy. This study used quasiexperimental
pretest-posttest design with control group with 35 respondents and
recruited by purposive sampling methode. Data were collected from patients with
peripheral diabetic neuropathy and had 8 maximum score of foot sensitivity.. Foot
sensitivity was measured on the 1st day of intervention and end day of intervention.
Mann whitney test analysis showed significant differences on foot sensitivity with
combination of diabetic legs exercise and SPA therapy compare to diabetic legs
exercise only (p value < 0.05). It can be inferred that combination of diabetic legs
exercise and SPA therapy are more effective to increase legs sensitivity. Therefore,
combined effect of those therapies may eventually decrease diabetic ulcers risk., Diabetic peripheral neuropathy patients with decreasing in foot sensation will
impact on diabetic ulcers. This study aims to explore the effect of combination
between diabetic legs exercise and SPA therapy on foot sensitivity escalation
among patients with diabetic peripheral neuropathy. This study used quasiexperimental
pretest-posttest design with control group with 35 respondents and
recruited by purposive sampling methode. Data were collected from patients with
peripheral diabetic neuropathy and had 8 maximum score of foot sensitivity.. Foot
sensitivity was measured on the 1st day of intervention and end day of intervention.
Mann whitney test analysis showed significant differences on foot sensitivity with
combination of diabetic legs exercise and SPA therapy compare to diabetic legs
exercise only (p value < 0.05). It can be inferred that combination of diabetic legs
exercise and SPA therapy are more effective to increase legs sensitivity. Therefore,
combined effect of those therapies may eventually decrease diabetic ulcers risk.]"
2015
T43551
UI - Tesis Membership  Universitas Indonesia Library
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Simbolon, Prabowo Wirjodigdo
"Latar belakang: Diperkirakan sekitar 15% penderita diabetes akan mengalami diabetic foot ulcer (DFU) dalam masa hidupnya. Negative Pressure Wound Therapy (NPWT) terbukti lebih efektif dibandingkan dengan perawatan konvensional. NPWT menciptakan lingkungan luka yang lembab, peningkatan aliran darah lokal dan merangsang jaringan granulasi sehingga mempercepat penyembuhan luka. Penelitian ini dilakukan untuk mengetahui faktor risiko yang memengaruhi lama rawat DFU dengan NPWT.
Metode Penelitian: Penelitian ini merupakan studi retrospektif dengan desain cross sectional analitik pada 105 subjek yang dirawat pada Januari 2016 sampai Desember 2018 di RS dr. Cipto Mangunkusumo. Karakteristik dan demografi pasien dan faktor risiko diambil dari rekam medik. Durasi perawatan dari aplikasi pertama NPWT hingga luaran sebagai hasil, kemudian dianalisis terhadap faktor risiko yang memengaruhinya.
Hasil Penelitian: Lama rawat DFU dengan NPWT adalah 19,9 ± 19,3 hari. Faktor risiko yang mempengaruhi lama rawat adalah riwayat ulkus (r = 0,01; p = 0,034), kedalaman luka (r = 0,292; p = 0.003), Hb (r = 0,05; p = 0,039), HbA1c (r = 0,06; p = 0,033), albumin (r = 0,06; p = 0,017), PCT (r = 0,10; p = 0,035), dan lama menderita DM (r = 0,193; p = 0,009).
Kesimpulan: Penelitian ini menunjukkan bahwa lama rawat DFU dengan NPWT dipengaruhi oleh faktor sitemik (lama menderita DM, Hb, HbA1c, albumin, dan PCT) dan faktor lokal (riwayat ulkus sebelumnya dan kedalaman luka). Kedalaman luka merupakan faktor yang paling berhubungan positif terhadap lama perawatan DFU pasca NPWT (r = 0,292, p = 0,003). Intervensi pada faktor risiko yang dapat diperbaiki sebelum penggunaan NPWT patut dilakukan untuk memaksimalkan penggunaan NPWT dan mengurangi lama perawatan.

Background: It is estimated that around 15% of diabetic patients will experience diabetic foot ulcer (DFU) in their lifetime. Negative Pressure Wound Therapy (NPWT) is proven to be more effective than conventional treatments. NPWT creates a moist wound environment, increases local blood flow and stimulates tissue granulation thereby accelerating wound healing. This study was conducted to determine the risk factors that affect the length of stay of DFU with NPWT. Knowing this risk factors may be helpful for optimizing management strategy.
Methods: This research is a retrospective study with a cross-sectional analytic design in 105 subjects treated in January 2016 to December 2018 at RS. dr. Cipto Mangunkusumo. Patient characteristics, demographics and risk factors were taken from medical records. The length of stay of the patient from the first application of NPWT to its outcomes was the main result, then the correlation to the risk factors that influence it was analyzed.
Results: The length of stay of DFU with NPWT was 19.9 ± 19.3 days. Risk factors affecting the length of stay were history of ulcers (r = 0.01; p = 0.034), wound depth (r = 0.292; p = 0.003), Hb (r = 0.05; p = 0.039), HbA1c (r = 0.06; p = 0.033), albumin (r = 0.06; p = 0.017), PCT (r = 0.10; p = 0.035), and duration of DM (r = 0.193; p = 0.009).
Conclusions: This study showed that the length of stay of DFU with NPWT was influenced by systemic factors (duration of DM, Hb, HbA1c, albumin, and PCT) and local factors (history of previous ulcers and wound depth). The depth of the wound was the most positively related factor to the length of stay in DFU post NPWT (r = 0.292; p = 0.003). Interventions on the risk factors that can be corrected before the application of NPWT may amplify the result of NPWT and reduce the length of treatment.
"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2019
SP-pdf
UI - Tugas Akhir  Universitas Indonesia Library
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Ria Desnita
"Perubahan bentuk kaki pada pasien neuropati diabetik mempengaruhi fungsi kaki sebagai landasan penopang dalam mempertahankan keseimbangan tubuh. Penelitian ini bertujuan untuk mengetahui hubungan bentuk kaki dengan keseimbangan fungsional pada pasien neuropati diabetik. Desain penelitian ini adalah analitik cross sectional dengan jumlah sampel 132 pasien neuropati diabetik. Analisis data menggunakan Chi Square, Pooled T-test, dan regresi logistik berganda. Hasil penelitian menunjukkan adanya hubungan antara bentuk kaki dengan keseimbangan fungsional pada pasien neuropati diabetik, dengan kekuatan hubungan sedang dan arah hubungan positif (p= 0,001; α= 0,05; r= 0,352). Penelitian ini merekomendasikan perawat untuk melakukan deteksi dini dan mencegah resiko jatuh pada pasien neuropati diabetik terkait perubahan bentuk kaki dan keseimbangan fungsional.

Changes in foot posture in diabetic neuropathy patients affects the function of the legs as the base of support in maintaining body balance. The study aimed to determine the correlation of foot posture with functional balance in diabetic neuropathy patients. This study design was analytic cross sectional, recruited 132 diabetic neuropathy patients. Statistical analysis used Chi Square, Pooled T-test, and multiple logistic regression. The results showed a significant correlation between foot posture and functional balance in diabetic neuropathy patients the power of correlation is moderate and positive direction (p= 0.001; α= 0.05; r= 0.352). This study suggests the nurse to perform early detection and prevention of the risk of falls in diabetic neuropathy patients related to changes in foot posture and functional balance.
"
Depok: Fakultas Ilmu Keperawatan Universitas Indonesia, 2016
T46400
UI - Tesis Membership  Universitas Indonesia Library
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