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Romilda Rosseti
Potensi Biomineralisasi Siler Berbasis Kalsium Silikat terhadap Permukaan Dentin Saluran Akar = Biomineralization Potential of Calcium Silicate Based Sealer on Root Canal Dentine
"lingkungan kondusif untuk proses penyembuhan. Biological sealing dapat diperoleh melalui sifat bioaktivitas suatu material, salah satunya kemampuan biomineralisasi material, yaitu kemampuan material dalam membentuk apatite like layer pada permukaan ketika berkontak dengan cairan fisiologis. Karakteristik tersebut dapat diperoleh dari material bioaktif, seperti kalsium silikat. Siler berbasis kalsium silikat pre- mixed saat ini telah banyak berkembang, di antaranya adalah Ceraseal® (Metabiomed, Korea) dan AH Plus® Bioceramic (Dentsply, USA). Komposisi masing-masing siler yang bervariasi menghasilkan perbedaan karakteristik, salah satunya kemampuan biomineralisasi. Tujuan: Menganalisis potensi biomineralisasi antara siler berbasis kalsium silikat pada dentin saluran akar dengan perendaman phosphate buffered saline (PBS). Metode: Siler berbasis kalsium silikat Ceraseal® dan AH Plus® Bioceramic diaplikasikan ke dalam dentin saluran akar gigi premolar yang telah dilakukan prosedur preparasi saluran akar, dan dilanjutkan dengan perendaman dalam PBS selama 14 hari. Analisis biomineralisasi dilakukan dengan menganalisis pembentukan lapisan apatit setelah 14 hari perendaman melalui penghitungan ketebalan deposit lapisan apatit menggunaan Scanning Electron Microscope (SEM), serta peningkatan pH larutan yang dihitung pada waktu observasi hari-ke 0, 7 dan 14 menggunakan pH-meter. Hasil: Terdapat perbedaan deposisi apatit pada interfacial layer antara Ceraseal® dan AH Plus® Bioceramic dalam waktu observasi 14 hari. Terdapat perbedaan bermakna antara nilai pH Ceraseal® dan AH Plus® Bioceramic pada waktu observasi 7 dan 14 hari.
Background: Endodontic treatment currently refers to the concept of biological sealing to form an environment conducive to the healing process. Biological sealing can be obtained through the bioactivity properties of a material, one of which is its biomineralization ability to form an apatite-like layer on the surface when in contact with physiological fluids. This characteristic is present in bioactive materials like calcium silicate. There are currently many developed pre-mixed calcium silicate based sealers, including Ceraseal® (Metabiomed, Korea) and AH Plus® Bioceramic (Dentsply, USA). The variation in their composition results in different characteristics, including biomineralization ability. Objective: To analyze the biomineralization potential of calcium silicate-based sealers on root canal dentine by phosphate-buffered saline (PBS) immersion. Methods Calcium silicate based sealer Ceraseal® and AH Plus® Bioceramic were applied to the root canal dentin of premolar teeth that had undergone root canal preparation procedures. The samples were then immersed in PBS for 14 days. Biomineralization analysis was performed by measuring the apatite layer thickness formed after 14 days of immersion using a Scanning Electron Microscope (SEM). Additionally, the pH of the solution was measured at observation times of 0,7 and 14 days using a digital pH-meter. Results: There was a significant differences in in apatite deposition at the interfacial layer between Ceraseal® and AH Plus® Bioceramic during 14 days of observation. Furthermore, there was a significant difference in pH values between Ceraseal® and AH Plus® Bioceramic at 7 and 14 days of observation."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2023
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UI - Tugas Akhir  Universitas Indonesia Library
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Indira Larasputri
Perbedaan Kemampuan Adhesi Siler Berbasis Kalsium Silikat Dan Resin Epoksi Terhadap Permukaan Dentin Saluran Akar = A Comparative Analysis of Adhesion Abilities between Calcium Silicate and Epoxy Resin based Sealers on Root Canal Dentine Surfaces
"Latar Belakang: Kemampuan adhesi siler terhadap dentin merupakan faktor penting dalam kesuksesan perawatan endodontik. Siler resin epoksi sebagai gold standart memiliki kemampuan adhesi yang superior, tetapi tidak memiliki sifat bioaktif sehingga berkembang siler kalsium silikat. Tujuan: Membandingkan kekuatan push-out bond strength dan failure mode siler AH Plus® Bioceramic dan Ceraseal dengan siler AH Plus®. Metode: Tiga puluh gigi premolar dibagi menjadi tiga kelompok untuk preparasi dan pengisian saluran akar menggunakan siler AH Plus® Bioceramic (kelompok 1), Ceraseal (kelompok 2) dan siler AH Plus® (kelompok 3). Sampel diinkubasi selama tujuh hari pada suhu 37oC, kemudian dipotong pada area sepertiga apikal dan medial. Nilai push-out bond strength dan failure mode dianalisis. Hasil: AH Plus® Bioceramic memiliki perbedaan nilai push-out bond strength dan failure mode yang signifikan dibanding AH Plus® dan Ceraseal. Ceraseal dan AH Plus® tidak memiliki perbedaan nilai secara signifikan. Analisis gambaran failure mode oleh dua orang observer menunjukkan reliabilitas data yang tinggi. AH Plus® Bioceramic memiliki dominasi kegagalan campuran, sedangkan Ceraseal dan AH Plus® memiliki persentasi kegagalan campuran dan kohesif yang seimbang. Kesimpulan: Seluruh kelompok siler menunjukkan kemampuan adhesi yang baik terhadap permukaan dentin, meskipun nilai push-out bond strength siler AH Plus® Bioceramic paling rendah diantara seluruh kelompok.
Background: The adhesion of sealers to dentin is important for successful endodontic treatment. As the gold standard, epoxy resin sealers have superior adhesion, but lack bioactive properties, hence the development of calcium silicate sealers. Objective: To compare the push-out bond strength and failure mode of AH Plus® Bioceramic and Ceraseal sealers with AH Plus® Sealer. Methods: Thirty premolars were divided into three groups for root canal preparation and obturation with AH Plus® Bioceramic (group 1), Ceraseal (group 2), and AH Plus® (group 3). The samples were incubated at 37°C for seven days, then cut at the apical and medial third. Push-out bond strength and failure mode were analyzed. Results: AH Plus® Bioceramic demonstrated significant differences in push-out bond strength and failure mode values compared to AH Plus® and Ceraseal. Ceraseal and AH Plus® were not significantly different. Analysis of failure mode descriptions by two observers showed high data reliability. AH Plus® Bioceramic had a predominance of mixed failures, whereas Ceraseal and AH Plus® had equal percentages of mixed and cohesive failures. Conclusion: All sealer groups showed good adhesion to the dentin surface, although the push-out bond strength value of AH Plus® Bioceramic sealer was the lowest among the groups."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2023
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UI - Tugas Akhir  Universitas Indonesia Library
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Putri Masyitha Hilmanudin
Karakterisasi Breksi serta Hubungan terhadap Mineralisasi Desa Cihaur dan Sekitarnya, Kecamatan Simpenan, Kabupaten Sukabumi, Provinsi Jawa Barat = Characterization of Breccia and Relationship to Mineralization in Cihaur Village and Surroundings, Simpenan District, Sukabumi Regency, West Java
"Wilayah penelitian terletak di Desa Cihaur, Kecamatan Simpenan, Kabupaten Sukabumi. Desa Cihaur merupakan salah satu daerah yang memiliki potensi timbal-emas karena area tersebut dilalui oleh jalur mineralisasi Pegunungan Selatan. Formasi yang menyusun area penelitian adalah formasi Jampang. Pada area penelitian tersingkap batuan breksi yang secara genetik belum diketahui jenisnya. Oleh karena itu, dilakukan studi mengenai Karakteristik breksi untuk mengetahui jenis dan keterkaitannya terhadap mineralisasi sehingga potensi logam ekonomis dapat diketahui dan dijadikan bahan pertimbangan eksplorasi. Metode yang digunakan pada penelitian adalah analisis petrologi pada 18 titik lubang bor, analisis petrografi sebanyak 9 sampel, dan analisis mineragrafi sebanyak 7 sampel. Berdasarkan hasil analisis didapatkan bahwa terdapat 4 jenis breksi yang menyusun wilayah penelitian, yaitu breksi vulkanik, breksi hidrotermal, breksi magmagtik-hidrotermal, dan breksi tektonik. Jenis mineralisasi yang ditemukan terdiri dari kelompok sulfida dan oksida. Kehadiran mineralisasi cukup melimpah pada breksi hidrotermal. Keterkaitan antara breksi dengan mineralisasi terletak pada genesanya. Proses keterbentukan menentukan komposisi klast dan matriks, permeabilitas, dan komposisi fluida. Parameter-parameter tersebut juga menjadi kontrol alterasi dan mineralisasi.
The research area is located in Cihaur Village, Simpenan District, Sukabumi Regency. Cihaur Village is one of the areas that has lead-gold potential because the area is traversed by the Southern Mountains mineralization route. The formation that makes up the research area is the Jampang formation. In the research area, breccia rocks were exposed, the genetic type of which is unknown. Therefore, a study was carried out on the characteristics of breccia to determine the type and its relationship to mineralization so that the potential for economic metals can be known and used as exploration consideration. The methods used in the research were petrological analysis at 18 drill hole points, petrographic analysis of 9 samples, and mineragraphic analysis of 7 samples. Based on the analysis results, there are four types of breccia in the research area, namely volcanic breccia, hydrothermal breccia, magmagtic-hydrothermal breccia, and tectonic breccia. The type of mineralization found consists of sulfide and oxide groups. The presence of mineralization is quite abundant in hydrothermal breccia. The relationship between breccia and mineralization lies in its genesis. The formation process determines the clast and matrix composition, permeability, and fluid composition. These parameters also control alteration and mineralization."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2024
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UI - Skripsi Membership  Universitas Indonesia Library
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Swesty Mahardhini
Perbedaan Kekuatan Adhesi Pasak Fiber Pada Perawatan Saluran Akar Menggunakan Siler Berbasis Resin Epoksi Dan Kalsium Silikat = The Difference of Fiber Post Adhesion Strength in Endodontic Treatment Using Epoxy Resin and Calcium Silicate-based Root Canal Sealer
"Latar Belakang: Penggunaan bahan semen (siler) saluran akar dengan kandungan dan karakteristik berbeda diduga dapat memengaruhi retensi pasak fiber terhadap dinding saluran akar pasca perawatan endodontik. Tujuan : Mengetahui perbedaan kekuatan adhesi pasak fiber pada perawatan saluran akar yang menggunakan siler berbasis resin epoksi dan kalsium silikat. Metode: 30 gigi premolar bawah akar tunggal didekoronasi, dilakukan preparasi saluran akar, lalu dibagi menjadi 3 kelompok; Kelompok 1 (kontrol): gigi tanpa pengisian saluran akar, Kelompok 2: gigi yang menggunakan siler resin epoksi (AH-Plus), dan Kelompok 3: gigi yang menggunakan siler berbasis kalsium silikat (Ceraseal). Setelah pengisian saluran akar, preparasi, dan pemasangan pasak fiber. Selanjutnya gigi dipotong pada area sepertiga tengah akar setebal 2 mm kemudian dilakukan uji push-out bond strength menggunakan Universal Testing Machine. Data dianalisis dengan tes One-way Anova dan post hoc Bonferroni. Hasil: Terdapat perbedaan bermakna nilai push-out bond strength antar kelompok semen resin resin epoksi dan kalsium silikat. Kesimpulan: Gigi yang melalui perawatan saluran akar menggunakan siler resin epoksi memberikan kekuatan adhesi pasak fiber yang lebih baik dibandingkan gigi yang menggunakan siler kalsium silikat.
Background: The use of root canal sealers with different composition and characteristics is thought to effect the retention of fiber post in root canal walls after endodontic treatment. Objective: To evaluate the difference of the fiber post adhesion strength after endodontic treatment using epoxy resin and calcium silicate based root canal sealer. Methods: 30 samples of single-rooted lower premolar were decoronated, got the root canal prepared, then divided into 3 groups; Group 1 (the controls): samples without root canal filling, Group 2 and 3, the canals were filled with gutta percha using epoxy resin (AH-Plus), and calcium silicate (Ceraseal)-based root canal sealer. After root canal obturation, the gutta percha were partly removed, prepared for post space, and then cemented with the fiber posts. Then 2 mm thick disk were cut from the middle root section and subjected to a push-out bond strength test. Data were analysed using the one-way ANOVA and post hoc Bonferroni test. Result: There was a significant difference in the push-out bond strength value between the epoxy resin and calcium silicate-based root canal sealer groups. Conclusion: The endodontic treated tooth previously using epoxy resin root canal sealer gave better fiber post adhesion strength compared to tooth that used calcium silicate based root canal sealer."
Depok: Fakultas Kedokteran Gigi Universitas Indonesia, 2020
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UI - Tesis Membership  Universitas Indonesia Library
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Stefani Astari Dewi Aryani
Perbedaan Kerapatan Siler Biokeramik Berbasis Kalsium Silikat Dengan Aktivasi Ultrasonik Terhadap Dinding Saluran Akar (Analisis Mikro-CT) = Differences on Sealing Ability of Bio-ceramic Calcium Silicate-Based Sealer with Ultrasonic Activation (Micro-CT Analysis)
"Latar Belakang: Pengisian saluran akar dengan teknologi terbaru siler premixed kalsium silikat pozolan dengan aktivasi ultrasonik dapat mengurangi porositas pengisian saluran akar. Reaksi pozolan menghasilkan siler dengan daya alir yang lebih baik dengan waktu pengerasan yang lebih cepat, terlebih dengan aktivasi ultrasonik yang akan mengurangi terbentuknya porositas dan meningkatkan kerapatan siler terhadap dinding saluran akar. Tujuan: Menganalisis perbedaan kerapatan siler berbasis kalsium silikat dan siler berbasis kalsium silikat pozolan dengan aktivasi ultrasonik dan tanpa aktivasi ultrasonik terhadap dinding saluran akar. Metode: Evaluasi kerapatan siler berbasis kalsium silikat dan kalsium silikat pozolan dengan aktivasi ultrasonik dan tanpa aktivasi ultrasonik terhadap dinding saluran akar pada 32 gigi premolar rahang bawah yang sudah diekstraksi yang dilihat dari persentase volume porositas pengisian saluran akar menggunakan dengan teknologi 3 dimensi Mikro-CT. Hasil: Siler berbasis kalsium silkat pozolan yang diaktivasi ultrasonik menunjukkan kerapatan siler saluran akar terhadap dinding saluran akar terbaik. Kesimpulan: Kerapatan siler berbasis kalsium silikat pozolan terhadap dinding saluran akar lebih baik dibandingkan siler berbasis kalsium silikat. Kerapatan siler yang diaktivasi ultrasonik terhadap dinding saluran akar juga lebih baik dibandingkan dengan yang tidak diaktivasi ultrasonik.
The latest technology of premixed calcium silicate pozzolan sealer with ultrasonic activation can reduce the porosity of root canal filling. Pozzolan reaction allows the sealer with better flow capacity with faster hardening time, especially with ultrasonic activation which will reduce the formation of porosity and increase sealing ability of root canal filling. Objective: Analyzing differences in sealing ability of calcium silicate-based sealers and calcium silicate pozzolan-based sealers with ultrasonic activation and without ultrasonic activation with 3D Micro-CT analysis. Methods: 32 samples of single rooted lower premolar were given root canal filling using gutta percha and calcium silicate-based sealers and with or without ultrasonic activation. Sealing ability was evaluated by measuring total porosity of the root canal filling. Group 1: calcium silicate-based sealer without ultrasonic activation, group 2: calcium silicate-based sealer with ultrasonic activation, group 3: calcium silicate pozzolan-based sealer without ultrasonic activation, and group 4: calcium silicate pozzolan-based sealer with ultrasonic activation. Result: Ultrasonic activated calcium silicate pozzolan-based showed the best sealing ability with lowest porosity. Conclusion: Calcium silicate pozzolan-based sealers have better sealing ability compared to calcium silicate-based sealers. The ultrasonic activated sealer groups also showed better sealing ability compared to the one that was not activated by ultrasonic."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2019
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UI - Tugas Akhir  Universitas Indonesia Library
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Raissa Ardelia Ahimsa
Adaptasi Siler Berbahan Dasar Kalsium Silikat dan Resin Epoksi pada Sepertiga Tengah Dinding Saluran Akar = Adaptation of Calcium Silicate and Epoxy Resin Sealers in Middle Third of Root Canal Wall
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Latar Belakang: Siler kalsium silikat bersifat hidrofilik, berikatan secara kimia ke dentin,  membentuk hidroksiapatit, memiliki waktu kerja dan settingideal, dan tidak terjadi penyusutan. Siler resin epoksi yang banyak digunakan saat ini memiliki kekurangan berupa adanya penyusutan saat mengeras. Evaluasi adaptasi siler dapat menentukan kemampuan kerapatan suatu siler. Salah satu metode untuk mengevaluasi kemampuan kerapatan siler adalah dengan Scanning Electron Microscopy (SEM). Tujuan: Menganalisis perbedaan adaptasi siler pada sepertiga tengah dinding saluran akar antara siler berbahan dasar kalsium silikat dengan resin epoksi.Metode: Tiga puluh dua sampel gigi premolar mandibula dibagi menjadi dua kelompok, yaitu kelompok 1: siler resin epoksi dan kelompok 2: siler kalsium silikat. Sampel dipreparasi dan diobturasi dengan siler berbahan dasar kalsium silikat dan resin epoksi. Selanjutnya, gigi dipotong vertikal dan disiapkan untuk analisis adaptasi siler menggunakan SEM. Data tersebut dianalisis secara statistik dengan uji Chi-square. Hasil Penelitian: Tidak terdapat perbedaan bermakna antara adaptasi siler kalsium silikat dan resin epoksi secara statistik (p>0.05). Partikel resin epoksi secara keseluruhan tampak berukuran lebih besar dibandingkan dengan kalsium silikat. Kesimpulan: Tidak terdapat perbedaan adaptasi siler secara statistik antara siler berbahan dasar kalsium silikat dengan resin epoksi pada sepertiga tengah dinding saluran akar, namun secara klinis sampel siler kalsium silikat lebih sedikit menunjukkan gap/ celah dan lebih banyak yang berpenetrasi ke dalam tubuli dentin dinding saluran akar.

Background: Calcium silicate sealer is hydrophilic, chemically bonded to dentin, forms hydroxyapatite, has an ideal working and setting time, and does not shrink. The epoxy resin sealer that is widely used today has the disadvantage of shrinkage when hardening. Evaluation of the adaptation of the sealer can determine the sealing ability of a sealer. One of the method for evaluating the sealing ability of a sealer is Scanning Electron Microscopy (SEM). Objective: To analyze differences in the adaptation of sealers in middle third of root canal wall between the calcium silicate and epoxy resin based sealer. Methods: Thirty-two mandibular premolar teeth samples were divided into two groups, that are group 1: epoxy resin sealer and group 2: calcium silicate sealer. Samples were prepared and obturated with calcium silicate and epoxy resin based sealer. Next, the teeth were cut vertically and prepared for analysis of the sealer adaptation using SEM. The data was analyzed statistically by Chi-square test. Results: There was no significant difference between the adaptation of calcium silicate and epoxy resin sealer statistically (p> 0.05). Overall epoxy resin’s particles appear larger than calcium silicate. Conclusion: There was no statistical difference in the adaptation of sealers between calcium silicate and epoxy resin based sealer in middle third of root canal wall, but clinically fewer calcium silicate sealer samples showed gaps and more penetrated into dentinal tubules of root canal wall.

 

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Depok: Fakultas Kedokteran Gigi Universitas Indonesia , 2019
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UI - Skripsi Membership  Universitas Indonesia Library
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Yura Muharsya
Perbandingan sealing ability pengisian saluran akar dengan siler bioceramic dan resin-metakrilat = Comparison sealability of root canal obturation using bioceramic sealer and methacrylate-resin based sealer
"ABSTRAK
Latar belakang: Siler dapat meningkatkan sealing ability Tujuan: Menganalisis dan membandingkan sealing ability pengisian saluran akar dengan siler bioceramic dan resin metakrilat. Metode: Tiga puluh gigi dengan saluran akar tunggal, dipreparasi dengan ProTaper Next, dibagi dalam dua kelompok secara acak; Masing-masing grup diisi dengan gutaperca berlapis, untuk kelompok 1 menggunakan Siler Bioceramic SB dan kelompok 2 Siler Resin-Metakrilat SRM . Pengukuran kebocoran dengan tinta india pada daerah sepertiga apikal apeks yang dipotong secara melintang, kemudian dilihat dengan mikroskop stereo. Hasil: Kelompok siler bioceramic menunjukkan celah tepi yang lebih sedikit jika dibandingkan dengan siler resin-metakrilat. Kesimpulan: Sealing ability pengisian saluran akar menggunakan siler bioceramic SB lebih baik dibandingkan dengan siler resin-metakrilat SRM .
ABSTRAK
Background Sealer may increase sealing ability. Purpose To compare and analyze sealability of obturation using the bioceramic sealer and methacrylate resin based sealer. Methods thirty single rooted teeth were prepared using ProTaper Next and divided randomly into two groups the first group was obturated with Bioceramic Sealer SB while the second group was obturated with methacrylate resin based sealer SRM . Each group used coated gutta percha as a core material. Apical third marginal adaptation was evaluated by observing the dye penetration between the obturation material and the root canal walls on cross sectioned samples. Results SB Showed the least microleakage in the apical third marginal adaptation, followed by SRM. Conclusion Obturation of root canal using bioceramic sealer has the best sealing ability at the apical third, compared to SRM."
2017
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UI - Tugas Akhir  Universitas Indonesia Library
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Wees Kaolinni
Potensi semen hidraulik dikalsium silikat kalsium dari cangkang telur dan silika sekam padi terhadap remineralisasi dentin: analisis in vitro = Dentin remineralization potential of eggshell calcium and rice husk silica dicalcium silicate hydraulic cement: an in vitro analysis
"Latar Belakang: Semen hidraulik C2SCS merupakan salah satu bahan bioaktif yang disintesis dari bahan alami, yaitu cangkang telur dan sekam padi. Tujuan: Mengetahui efek semen C2SCS dari cangkang telur dan sekam padi terhadap peningkatan derajat kristalinitas hidroksiapatit dentin. Metode: 24 sampel gigi dibuat kavitas buatan dan dibagi menjadi 4 kelompok. Kelompok 1 (dentin normal) sebagai kontrol, kelompok 2 dentin demineralisasi, kelompok 3 dentin demineralisasi diaplikasi semen C2SCS dengan rasio pencampuran 1:1, kelompok 4 dentin demineralisasi diaplikasi semen C2SCS rasio 1:2. Seluruh sampel disimpan dalam shaking incubator pada suhu 37° C selama 14 hari. Kemudian sampel gigi tersebut diperiksa dengan XRD dan SEM untuk melihat peningkatan jumlah kristal hidroksiapatit dentin. Hasil: Terdapat peningkatan derajat kristalinitas hidroksiapatit dentin setelah aplikasi semen C2SCS rasio 1:1 yang nilainya berbeda bermakna dengan dentin demineralisasi, dan tidak berbeda bermakna dengan dentin sehat (kontrol positif). Semen C2SCS rasio 1:1 lebih berpotensi untuk meningkatkan pembentukan kristal hidroksiapatit pada dentin demineralisasi dibanding rasio 1:2 Kesimpulan: Semen C2SCS dari cangkang telur dan sekam padi memiliki potensi untuk meremineralisasi dentin. Semen C2SCS rasio 1:1 memiliki potensi remineralisasi dentin yang lebih tinggi dibanding kelompok lainnya.
Background: C2SCS cement is one of bioactive material synthesized from natural material, such as eggshell calcium and rice husk silica. Objective: To determine the effect of C2SCS cement made from eggshell and rice husk silica to the increase of degree of cristallinity of dentin hydroxyapatite. Methods: Artificial cavity was made in 24 tooth sample, which then divided into 4 groups. Group 1 is normal dentin as the positive control group. Group 2 is demineralized dentin. Group 3 is demineralized dentin applied with C2SCS cement in mixing ratio of 1:1. Group 4 is demineralized dentin applied with C2SCS cement in mixing ratio of 1:2. All samples are stored inside a shaking incubator at a temperature of 37 C. An examination using XRD was done to all samples to see the degree of cristallinity of dentin hydroxyapatite, and a SEM image is taken to see morphology and microstructure of hydroxyapatite. Result: There is a significant increase of degree of cristallinity of dentin hydroxyapatite after C2SCS cement application with 1:1 ratio compared to demineralized dentin, and insignificant difference with normal dentin. C2SCS cement in 1:1 ratio has more potential to increase the formation of hydroxyapatite crystal compared to 1:2 ratio. Conclusion: C2SCS cement made from eggshell and rice husk silica has the potential to remineralize dentin. C2SCS cement in 1:1 ratio has more remineralization potential compared to other groups."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2022
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UI - Tugas Akhir  Universitas Indonesia Library
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Nurina Anggraeni Pratiwi
Perbandingan kebocoran mikro antara pengisian saluran akar dengan siler resin epoksi dan polidimetilsiloksan generasi baru pada sepertiga apeks = The comparison of microleakage of obturation with epoxy resin based and new generation polydimethylsiloxane based root canal sealer in one third apical root canal
"Latar Belakang: Siler yang baik adalah yang memiliki tingkat kebocoran mikro yang rendah Penelitian ini bertujuan untuk menganalisis siler golongan resin SRE dan polidimetilsiloksan generasi baru SPGB
Metode: Tiga puluh dua gigi premolar bawah dibagi dua kelompok sama besar yaitu kelompok SRE dan SPGB Setelah pengisian saluran akar dengan teknik kondensasi lateral sampel diinkubasi 370C 24 jam mahkota dipotong menyisakan bagian akar 15 mm dilapis cat kuku kecuali 1 mm dari apeks lalu direndam dalam tinta India selama 7 X 24 jam Lalu sampel didekalsifikasi dengan asam nitrat 5 didehidrasi berturut turut dengan alkohol 80 90 dan 100 dan dibuat transparan dengan metil salisilat 100 Kedalaman penetrasi tinta dievaluasi dengan mikroskop stereo Skor 1 untuk penetrasi tinta 0 0 5 mm skor 2 untuk penetrasi tinta 0 51 1 mm dan skor 3 untuk penetrasi tinta 1 mm
Hasil: Distribusi proporsi kebocoran terbesar kelompok SRE terdapat pada skor 2 yaitu sebesar 56 3 Sedangkan distribusi proporsi kebocoran terbesar kelompok SPGB terdapat pada skor 1 yaitu sebesar 68 8 Dengan tes Kolmogorov Smirnov terdapat perbedaan bermakna antara kelompok SRE dan SPGB
Kesimpulan: Kebocoran mikro pengisiansaluran akar pada sepertiga apeks dengan siler polidimetilsiloksan generasi baru lebih rendah dibandingkan dengan siler resin epoksi
Background: An ideal root canal sealer should have good sealing ability The purpose of this study was to analyze the microleakage of obturation using epoxy resin based SRE and new generation polydimethylsiloxane based SPGB as root canal sealer
Methods: Thirty two mandibular first premolars were equally divided into two groups and obturated with lateral condensation technique The sealer used for Group I and Group II were SRE and SPGB respectively After obturation the specimens were incubated 370C 24 h decoronated sealed with nail polish except 1mm from apex immersed in Indian ink for 7 days decalcified with 5 nitric acid solution dehydrated with 80 90 and 100 alcohol consecutively and made transparent by immersing them in 100 methyl salicylate Dye penetration were evaluated under stereomicroscope and givenscore 1 3 Specimen with 0 0 5 mm dye penetration was given score 1 while 0 51 1 mm penetration was given score 2 and 1 mm was given score 3 The results were statistically analyzed with Kolmogorov Smirnov test
Results: The largest proportion distribution in SR group was score 2 56 3 whilst the largest proportion distribution in SPGB group was score 1 68 8 There was a significant difference between the microleakage of epoxy resin based and new generation polydimethylsiloxane based sealer observed from the one third apical leakage
Conclusion: The microleakage of new generation polydimethylsiloxanebasedsealer is lower than epoxy resin based sealer"
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2013
T32929
UI - Tesis Membership  Universitas Indonesia Library
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Ike Dwi Maharti
Potensi Novel Hibrida Biokeramik- Kitosan Larut Air sebagai Semen Biomimetik Saluran Akar = Potential Novel Hybrid Bioceramic- Water-Soluble Powder (WSP) Chitosan as Root Canal Biomimetic Sealer
"Latar Belakang: Siler biokeramik berbasis kalsium silikat diketahui memiliki biokompabilitas tinggi, mampu beradhesi dengan dinding saluran akar serta dapat menginduksi respon osteogenik, yang dikategorikan sebagai material biomimetik. Akan tetapi, siler biokeramik memiliki kekurangan pada sifat fisiknya. Kitosan larut air merupakan bentuk modifikasi kitosan yang memiliki keunggulan sebagai antioksidan, antibakteri, berperan dalam penyembuhan lesi dan regenerasi jaringan serta sebagai dapat memperbaiki sifat fisik semen. Perpaduan kedua bahan dapat menciptakan semen saluran akar biomimetik.
Tujuan: Melakukan uji karakteristik, sifat fisik dan biologis terhadap novel siler hibrida biokeramik-kitosan larut air (BCC) sebagai semen biomimetik saluran akar.
Metode: Novel siler hibrida BCC dimanipulasi dari semen biokeramik (BC) yang telah melalui proses ball-milling dan sintering, kemudian dicampur kitosan larut air dengan W/P 0,4. Empat variabel penelitian, yaitu semen biokeramik BC, novel siler hibrida BCC, siler biokeramik dan siler epoksi resin dilakukan uji karakterisasi (XRD, SEM/EDS), uji sifat fisik (setting time, daya alir, film thickness), serta uji biologis (sitotoksisitas dan bioaktivitas terhadap hPDLSCs).
Hasil: Novel siler hibrida BCC mengandung unsur dan puncak kristalin yang serupa dengan siler biokeramik (Sure-Seal Root™), memiliki bentuk partikel yang cenderung globular dan homogen dengan jarak antarpartikel lebih rapat serta ukuran partikel deskriptif yang lebih besar dibandingkan Sure-Seal Root™ dan AH Plus® tetapi lebih kecil dibandingkan semen biokeramik BC. Hanya semen biokeramik BC dan novel siler BCC yang memiliki rasio Ca/Si/P. Novel siler BCC menunjukkan perbedaan setting time, daya alir dan film thickness yang bermakna dengan semen biokeramik BC, Sure-Seal Root™ dan AH Plus®. Keempat kelompok menunjukkan sitotoksisitas rendah terhadap hPDLSCs. Bioaktivitas novel siler BCC relatif lebih tinggi dibandingkan semua kelompok perlakuan dan kontrol.
Kesimpulan: Novel siler hibrida BCC berpotensi memberikan implikasi klinis yang baik, menunjukkan sifat fisik yang mendekati standar semen saluran akar dan memiliki bioaktivitas sebagai semen biomimetik saluran akar.
Background: Currently, bioceramic sealers with calcium silicate based have been developed and show high biocompatibility, are able to adhere to root canal dentin and can induce an osteogenic response, which can be categorized as biomimetic materials. On the other hand, water-soluble particle (WSP) chitosan, one of chitosan derivatives, has advantages as an antioxidant, antibacterial, plays a role in wound healing and tissue regeneration as well as a thickening agent. The combination of these two materials can create a biomimetic endodontic sealer.
Objective: To examine the characteristics, physical and biological properties of novel bioceramic-chitosan hybrid sealer (BCC) as biomimetic endodontic sealer.
Methods: Novel BCC sealer were manipulated from bioceramic cement (BC) which had been synthesized through a ball-milling and sintering process, then mixed with WSP chitosan with a W/P of 0,4. Four variables, namely novel BCC sealer, BC bioceramic cement, bioceramic and epoxy resin sealer were tested characterization (XRD, SEM/EDS), physical properties (setting time, flow, film thickness), and biological tests (cytotoxicity and bioactivity on hPDLSCs).
Results: Novel BCC sealer showed bioceramic elements and crystalline peaks similar to bioceramic sealer (Sure-Seal Root™), had a particle shape that tends to be globular and homogeneous with descriptive particle size larger than Sure-Seal Root™ and AH Plus® but smaller compared to BC bioceramic cement. Only BC bioceramic cements and novel BCC sealer had Ca/Si/P ratios. Novel BCC sealer showed significant differences in setting time, flow, and film thickness with BC bioceramic cements, Sure-Seal Root™ and AH Plus®. The four groups showed low cytotoxicity to hPDLSCs. The bioactivity of novel BCC sealer was relatively higher among other groups and control group.
Conclusion: Novel BCC hybrid sealer has good clinical implications, exhibit physical properties close to standard root canal cements and have bioactivity as root canal biomimetic sealer."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2022
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