Hasil Pencarian  ::  Simpan CSV :: Kembali

"Rokok dianggap sebagai faktor risiko strok yang dapat dicegah, tetapi mekanisme rokok sebagai penyebab strok masih merupakan kontroversi. Beberapa penelitian menganggap bahwa rokok sangat erat kaitannya dengan kadar fibrinogen plasma. Maka penelitian ini dilakukan untuk menilai peranan rokok terhadap kadar fibrinogen pada penderita stroke iskemik akut perokok. Penelitian kasus kelola ini dilakukan dari Oktober 1995 sampai Jull 1996 di Bag. Neurologi RSUPN Cipto Mangunkusumo Jakarta dan sampel penderita dibagi dalam dua kelompok yaitu, kelompok I: strok perokok 35 penderita (kasus) , kelompok II: strok non perokok 35 penderita (kontrol). Pemeriksaan fibrinogen dilakukan paling lambat hari ke 5 setelah onset strole, dengan metode chromotimer.

---

Smoking has been considered to be one of the preventable risk factors of stroke but its mechanism causing stroke is still controversial. There were many studies showing that smoking were strongly related to high serum fibrinogen level in acute ischemic stroke patients. This case control study was conducted to asses the role of smoking on serum fibrinogen level in acute ischemic stroke patient hospitalized in Neurological ward Dr. Cipto Mangunkusumo hospital Jakarta from October 1995 until July 1996. We divided the subject into two categories as follows, group I: smokers with stroke 35 patients (cases), group II: non smokers with stroke 35 patients (control). Fibrinogen serum level measurements were done at least on the 5th day after stroke

onset with chromotimer methode."

"Merokok merupakan masalah kesehatan masyarakat di dunia, menurut World Health Organization (WHO 1988), kebiasaan merokok cenderung meningkat akhir-akhiir ini yaitu 50% pada laki-laki dan 8% pada wanita. Rokok adalah faktor risiko dari strok yang dapat dicegah (klasifikasi serebro vascular diasease III 1990), akan tetapi mekanisme rokok sebagai penyebab strok masih kontroversi. Barigarımenteria (1993) pada penelitianya menganggap rokok sebagai faktor risiko strok yang dapat menurunkan kadar protein S. Penelitian ini bertujuan untuk melihat pengaruh rokok terhadap penurunan kadar protein S pada strok iskemik fase akut. Penelitian dilakukan di Bagian Penyakit Saraf RSUPN-CM sejak bulan Mei 1996 sampai dengan Februari 1997 dengan disain kanıs kontrol pada 45 penderita strok iskemik akut perokok dan 45 penderita strok iskemik akut non perokok yang memenuhi kriteria inklusi. Semua penderita Paki-laki dengan rentang usia seluruh penderita 40 74 tahun. Pemeriksaan protein S dilakukan pada fase akut selambat-lambatnya hari keenam setelah serangan, menggunakan metode koagulometrik. Nilai standard protein 3 untuk orang Indonesia 76% 121,2%. Penilaian hasil aktifitas kadar protein S menurun bila nilai kurang dari 76%. Rerata usia pada kasus 57,2 ± 7,5, tahun dan rerata usia kontrol 56,9 ± 7,9 tidak terdapat perbedaan yang bermakna antara usia kasus dan kontrol (p=0,421). Rerata lama merokok 15,6 ± 8 talaan, 71% (32 orang) merokok lebih dari 10 tahun dan 28,8% (13 orang), merokok kurang dari 10 tahun, didapatkan perbedaan yang bermakna penurunan aktifitas protein S antara kasus dan kontrol (X 11,37, p- 0,0018; Ratio Odds 11,2). Rerata jumlah rokok yang dikonnanai perhari 15 ± 8 batang perhari, 35,5% (16 orang) merokok lebih dari 20 batang perhari, 64,4% (29 orang) merokok kurang dari 20 batang perhari (X²-4,45; p 0,0349, Ratio Odds-7,89). Semua penderita perokok kretek, 26,78% (12 orang) perokok kretek filter dan 73,3% (33 orang) perokok kretek non filter. Tidak didapatkan perbedaan bermakna perokok kretek filter dan non kretek filter (X=0,72; p = 0,403). Didapatkan penurunan aktifitas kadar protein S yang bermakna pada kasus dibanding dengan kontrol (Ratio Odds 14,3). Rata-rata aktifitas kadar protein S pada kasus 50,6% dan rata-rata pada kontrol 85,5%, terlihat perbedaan yang bermakna dengan uji t-test 7,5; p 0,0001. Tujub puluh lima persentil aktifitas kadar protein S menurun dibawah nilai standard normal pada kasus dan hanya lima belas persentil pada kontrol. Lama merokok dan jumlah rokok yang dikonsumsi setiap hari mempunyai pengaruh yang bermakna terhadap penurunan aktifitas kadar protein S (t-test-4,25; p- 0,0001; 95% CI 15,5-45,7) dan (t-test = 2,65; p=0,011; 95% CT 4,1-30,2.

---

Smoking is a public health problem in the world, according to the World Health Organization (WHO 1988), smoking habits tend to increase recently, namely 50% in men and 8% in women. Cigarettes are a risk factor for preventable stroke (cerebro vascular disease classification III 1990), however the mechanism of smoking as a cause of stroke is still controversial. Barigarımenteria (1993) in his research considered smoking as a risk factor for stroke which can reduce protein S levels. This study aims to see the effect of smoking on reducing protein S levels in the acute phase of ischemic stroke. The research was conducted in the Neurological Diseases Department of RSUPN-CM from May 1996 to February 1997 with a control design on 45 acute ischemic stroke sufferers who were smokers and 45 sufferers of acute ischemic stroke who were non-smokers who met the inclusion criteria. All Paki sufferers were male with an age range of 40 to 74 years. Protein S examination is carried out in the acute phase no later than the sixth day after the attack, using the coagulometric method. The standard value of protein 3 for Indonesians is 76% 121.2%. Assessment of activity results means S protein levels decrease if the value is less than 76%. The mean age of cases was 57.2 ± 7.5 years and the mean age of controls was 56.9 ± 7.9. There was no significant difference between the ages of cases and controls (p=0.421). The average number of cigarettes consumed per day was 15 ± 8 cigarettes per day, 35.5% (16 people) smoked more than 20 cigarettes per day, 64.4% (29 people) smoked less than 20 cigarettes per day (X²-4.45; p 0.0349, Odds Ratio-7.89). All sufferers were kretek smokers, 26.78% (12 people) were filter kretek smokers and 73.3% (33 people) were non-filter kretek smokers. There was no significant difference between filtered kretek and non-filtered kretek smokers (X=0.72; p = 0.403). There was a significant decrease in the activity of protein S levels in cases compared to controls (Odds Ratio 14.3). The average activity level of protein S in cases was 50.6% and the average in controls was 85.5%, showing a significant difference using the t-test of 7.5; p 0.0001. Seventy-fifth percentile activity levels of protein S decreased below normal standard values ​​in cases and only fifteen percentiles in controls. Length of smoking and the number of cigarettes consumed each day had a significant influence on reducing the activity of protein S levels (t-test-4.25; p-0.0001; 95% CI 15.5-45.7) and (t-test = 2.65; p=0.011; 95% CT 4.1-30.2."

"LATAR EELAKANGKejadian stroke menimbulkan kerusakan sel otak. Berbagai faktor risiko telah dikenal meliputi faktor risiko mayor dan minor. Kadar magnesium endogen sebagai salah satu faktor risiko kerusakan set otak masih belum banyak dianalisa dengan berbagai hasil penelitian yang masih kontroversial.METODEPenelitian ini merupakan penelitian prospektif longitudinal (retreated measurement design) dengan data printer diperoleh dari penderita stroke iskemik yang berobat ke RSCM yang memenuhi kriteria inklusi dan eksklusi. Diagnosis stroke iskemik dilakukan melalui pemeriksaan klinis dan CT Scan atau MRI kepala. Dilakukan pemeriksaan laboratorium darah, analisa urin, EKG, dan foto thoraks pada saat masuk. Dilakukan pemeriksaan magnesium serum, plasma, eritrosit pada hari ke-2, ke-4 dan ke-7 dan skor NIHSS pada hari dan saat yang sama.HASILJumlah objek penelitian 53 orang. Sebagian besar rerata magnesium serum dan plasma dalam batas normal (1,4-2,0 mmEq/l) pada tiap hari pengambilan (Mg serum 67,9% - 90,6%, Mg plasma 75-5% - 88,7%) sedangkan ditemukan hipoMg eritrosit pada hari ke-4 dan ke-7 onset stroke (81,1 % dan 73,6%). Ditemukan hubungan sangat bermakna antara Mg serum dengan Mg plasma pada tiap hari pengambilan (p=0,000) dan hubungan bermakna antara Mg serum dengan Mg eritrosit (p=0,02) dan Mg plasma dan Mg eritrosit (p=0,033) pada hari ke-4. Ditemukan hubungan bermakna independen antara Mg plasma hari ke-4 dengan NIHSS hari ke-4 (p=0,005) di samping faktor risiko riwayat stroke /TIA, aritmia jantung dan hiperkoleslerolemia dengan NIHSS.KESIMPULANPenderita iskemik serebral menunjukkan perubahan kadar Mg serum, plasma, eritrosit yang dipengaruhi berbagai faktor risiko lain dan hubungan bermakna antara kadar Mg plasma dan skor NIHSS hari ke-4.KATA KUNCI: Stroke iskemik, hipertensi, magnesium serum, plasma, eritrosit, NIHSS.

---

PREFACE

Stroke causes damage to brain cells. Many risk factors of stroke are known like mayor and minor risk factors. Endogen magnesium level as one of risk factor of brain cell damage is analyzed rarely with the controversially results of its studies.

METHOD

The design of this study was repeated measurement with its primary data were collected from ischemic stroke patients in Cipto Mangunkusumo hospital who fulfilled inclusion and exclusion criteria. Diagnosis of stroke was made by physical exam, CT scan or head MRI and completed by blood and urine analysis, echocardiography and chest photo. Serum, plasma and erythrocyte Mg were collected on the 2nd, 4th, aid 7th days after onset and compared with NIHSS scores at the same times.

RESULT

There are 53 persons of subjects studied. Almost all means of the serum Mg and plasma Mg were in normal limits (1,4-2,0 mEq/l) on every days of data collection (serum Mg : 67,6%-90,6%, plasma Mg : 75,5%-88,7%), but there were erythrocyte hipoMg on the 4th and 7th days of stroke onset (81,1% and 73,6%). There were very significant relationship between serum Mg with plasma Mg (p=0,000) on every days of data collection and significant relationship between serum Mg with erythrocyte Mg (p=0,02) and plasma Mg with erythrocyte Mg (p 1,033) on the 4th day onset. There were significant independent relationship between plasma Mg on the 4th day onset with NIHSS in the same day (p=0,005), besides between the history of stroke/TIA, aritmia and hypercholesterolemia with NIHSS.

CONCLUSION

Cerebral ischemic patients showed changes of serum, plasma and erythrocyte Mg levels which were influenced by other risk factors and there was significant relationship between plasma Mg and NIHSS score in the 4th day."

"Latar Belakang: Stroke merupakan penyakit yang memiliki perbedaan karakteristik antara pria dan wanita. Tujuan: Penelitian bertujuan untuk mengetahui hubungan jenis kelamin dengan fungsi kognitif yang dinilai menggunakan uji Montreal Cognitive Assesment versi Indonesia MoCA-Ina pada pasien stroke fase subakut dan kronik di Departemen Rehabilitasi Medik RSCM, dengan melakukan kontrol terhadap variabel perancu berupa tingkat pendidikan dan usia. Metode: Penelitian merupakan studi observasional analitik dengan desain potong lintang. Sampel penelitian sebanyak 34 subjek, diperoleh melalui teknik consecutive sampling. Analisis bivariat uji Mann-Whitney dan uji korelasi Pearson dilakukan untuk melihat hubungan antarvariabel, dan dilanjutkan dengan analisis multivariat regresi linier. Hasil: Berdasarkan uji Mann-Whitney diperoleh nilai p hubungan jenis kelamin dan tingkat pendidikan dengan skor MoCA-Ina sebesar 0,103 dan 0,076. Nilai korelasi hubungan usia dengan skor MoCA-Ina berdasarkan uji korelasi Pearson sebesar r=0,135 p=0,447 . Persamaan regresi skor MoCA-Ina=21,268-3,620 Wanita 3,762 Pendidikan Tinggi R2=8,6 . Perbedaan rerata skor MoCA-Ina antara pria dan wanita setelah dilakukan kontrol variabel tingkat pendidikan adalah sebesar -3,620 IK95 =-8,928-1,058 , namun secara statistik tidak bermakna p=0,125. Diskusi: Tidak ada perbedaan signifikan pada fungsi kognitif yang dinilai menggunakan MoCA-Ina antara pasien stroke sub-akut dan kronik pria dan wanita.

---

Background: Stroke is a disease with different characteristics between men and women.

Objective: This study aims to determine the age and level of education adjusted relationship between gender and cognitive function which is assessed by Montreal Cognitive Assessment in sub acute and chronic stroke patients in the Department of Rehabilitation Medicine RSCM.

Methods: This study is an analytic observational study with a cross sectional design. 34 subjects were selected as samples with consecutive sampling method. Mann Whitney test and Pearson's correlation test were used in to determine the bivariate relationships between the variables, proceeded by a multivariate linear regression analysis.

Results: Based on the Mann Whitney test, the p value of the relationship between gender and the level of education and MoCA Ina score were p 0,103 and p 0,076 respectively. Correlation value between age and MoCA Ina score was r 0,135 p 0,447. The regression equation generated was MoCA Ina score 21,268 3,620 Women 3,762 Higher Education R2 8,6. The mean difference of MoCA Ina score between men and women stroke patients after adjusting for age and level of education was 3,620 CI 95 8,928 1,058, but it was statistically insignificant p 0,125.

Discussion: There was no significant difference in the cognitive function which is assessed by MoCA Ina between the male and female sub acute and chronic stroke patients."

"[Latar belakang dan tujuan: Delapan puluh persen stroke merupakan stroke iskemik. Penatalaksanaan harus segera meliputi tindakan revaskularisasi dan pencegahan sekunder. Penelitian ini bertujuan menilai kesesuaian antara MRI sekuens DWI dan ADC dengan MRI sekuens konvensional pada stroke iskemik hiperakut dan akut, serta mendapatkan nilai ADC pada stroke iskemik hiperakut dan akut. Metode: Studi diagnostik cross-sectional pada pasien-pasien stroke yang menjalani pemeriksaan MRI sekuens konvensional serta MRI sekuens DWI dan ADC. Hasil pemeriksaan MRI tersebut lalu dibandingkan. Hasil: Pemeriksaan MRI konvensional: 3 populasi dinyatakan hiperakut, 31 akut dan 12 normal (p Mc Nemar < 0,05, analisa Kappa sebesar R=-0,369). Pada pemeriksaan MRI sekuens DWI: 14 populasi dinyatakan hiperakut dan 32 akut (p Mc Nemar > 0,05, analisa Kappa R=0,553). Nilai ADC stroke iskemik hiperakut adalah 0,57 x 103 mm2/detik, SD 0,091 x 103 mm2/detik; pada stroke iskemik akut sebesar 0,52 x 103 mm2/detik, SD 0,097 x 103 mm2/detik, hasil T test didapatkan p>0.05. Kesimpulan: MRI sekuens DWI dan ADC lebih unggul dalam menentukan onset stroke iskemik hiperakut dan akut dibandingkan MRI konvensional. Nilai ADC untuk stroke iskemik hiperakut memiliki kecenderungan lebih tinggi dibandingkan stroke iskemik akut., Background and Objectives: Eighty percent of strokes are ischemic strokes. Management of ischemic stroke including revascularization and secondary prevention should be done. This study aims to assess the appropriateness between DWI and ADC MRI sequences with conventional MRI sequences in hyper acute and acute ischemic stroke, as well as get ADC values in hyper acute and acute ischemic stroke. Methods: Cross sectional diagnostic approach in patients stroke who had been undergoing conventional MRI sequences, ADC and DWI MRI sequences. The results of the MRI examinations were compared. Results: In conventional MRI examination: 3 hyper acute, 31 acute and 12 normal(Mc Nemar p<0,05, Kappa analysis R=-0,369). DWI MRI sequences: 14 hyper acute and 32 acute(Mc Nemar p>0,05, Kappa analysis R = 0,553). ADC value hyper acute ischemic stroke is 0,57 x 103mm2/sec, SD 0,091 x 103 mm2/sec; in acute ischemic stroke is 0,52 x 103mm2/sec, SD 0,097 x 103mm2/sec, T test results obtained p>0,05. Conclusion: ADC and DWI MRI sequences are superior in determining the onset of hyper acute and acute ischemic stroke compared to conventional MRI. ADC value for hyper acute ischemic stroke have a higher tendency than acute ischemic stroke.]"

"Latar Belakang: Ankle Brachial Index (ABI) merupakan pemeriksaan noninvasif sederhana dan akurat untuk penyaring dan diagnostik Penyakit Arteri Perifer (PAP). Nilai ABI abnormal merupakan prediktor penting terjadi aterosklerosis sistemik yang menjadi penyebab stroke dan penyakit kardiovaskuler. Nilai ABI rendah berhubungan dengan telah tezjadi aterosklerosis sistemik atau PAP. Setelah lima tahun kemudian 25-35% penderita PAP akan mendenita stroke atau infark miokard. Faktor risiko stroke iskemik yang berhubungan dengan proses aterosklerosis adalah hipertensi, dislipidemia, homosisteinemia, merokok, infeksi dan hiperglikemia. Tujuan: Mengetahui gambaran nilai ankle brachial index pada penderita stroke iskemik di RSUPN Cipto Mangunkusumo Jakarta. Metode: Penelitian ini dilakukan menggunakan disain potong lintang deskriptif analitik pada 73 penderita stroke iskemik. Kemudian dilakukan anamnesis, pemeriksaan fisik umum, pemeriksaan neurologi rutin, pemeriksaan kadar total kolesterol darah, trigliserida, LDL, HDL, GDS, dan dilakukan pemeriksaan ABI. Pasien yang tidak memiliki CT scan / MRI kepala tidak masuk dalam penelitian. Hasil: Dari 73 subyek penelitian didapatkan sebaran umur terbanyak pada kelompok umur 55-64 tahun (42,5%) dan sebagian besar subyek (78.1%) memiliki hipertensi. Proporsi nilai ABI abnormal pada penderita stroke iskemik adalah 26,0 %. Faktor risiko yang bermakna Secara Statistik dengan analisis bivariat adalah kadar total kolesterol darah p=0,039 dan umur p=0,034. Seclangkan hasil analisis multivariate menunjukkan bahwa kelompok umur merupakan faktor risiko independen yang bermakna terhadap nilai ABI abnormal dengan p-value 0,023 (OR 2,556; IK 95% 1,136-5,752). Kesimpulan: Penderita stroke iskemik berumur lebih dari 55 tahun merupakan faktor risiko yang berhubungan terhadap kejadian nilai ABI abnormal. Sedangkan hiperkolesterolemia merupakan faktor risiko yang mempunyai hubungan yang bermakna dengan nilai ABI abnormal."

"Tesis ini disusun untuk menilai hubungan tingkat disabilitas pasien stroke dengan tingkat kualitas hidup pelaku rawat informal. Desain penelitian adalah studi potong lintang dengan menilai tingkat disabilitas pasien stroke menggunakan Indeks Barthel Modifikasi Shah dan tingkat kualitas hidup pelaku rawat informal dengan SF-36. Subjek penelitian adalah 50 orang pasien stroke kronis dan 50 orang pelaku rawat informal. Wawancara dilakukan melalui tatap muka langsung (23 orang pasien stroke dan 23 orang pelaku rawat informal) dan melalui tatap muka video call (27 orang pasien stroke dan 27 orang pelaku rawat informal). Penelitian ini mendapatkan bahwa nilai tengah tingkat disabilitas pasien stroke adalah 82,5 (16 – 100) dan nilai rerata tingkat kualitas hidup pelaku rawat informal adalah 69,69 + 20,32. Nilai subskala kualitas hidup pelaku rawat informal untuk komponen fisik adalah 73,7 (20,63 – 97,5) dan komponen mental adalah 69,8 + 21,93. Dilakukan uji korelasi Spearman antara Indeks Barthel Modifikasi Shah dan SF-36 dengan hasil yang didapatkan adalah korelasi positif sedang yang signifikan (r=0,6, p<0,001). Kesimpulan penelitian ini adalah terdapat hubungan korelasi positif sedang yang bermakna antara tingkat disabilitas pasien stroke dengan tingkat kualitas hidup pelaku rawat informal.

---

This thesis is designed to determine the correlation between disability level of stroke patient and quality of life of informal caregiver. The research design is a cross sectional study using Shah Modified Barthel Index to assess the disability level of stroke patient and SF-36 to assess quality of life of informal caregiver. Subjects of this study is 50 stroke patients and 50 informal caregivers. The interview was done by direct face to face setting (for 23 stroke patients and 23 informal caregivers) and indirect face to face setting using video call (for 27 stroke patients and 27 informal caregivers). The median score of disability level of stroke patient in this study is 82,5 (16 – 100) and mean score of quality of life of informal caregiver is 69,69 + 20,32. The score for the subscales of quality of life are 73,7 (20,63 – 97,5) for physical components and 69,8 + 21,93 for mental components. Spearman correlation test was done for disability level of stroke patient and quality of life of informal caregiver which resulted moderate positive correlation (r=0,6, p<0,001). This study concluded that there is moderate positive correlation between disability level of stroke patient and quality of life of informal caregiver."

"[ABSTRAKLATAR BELAKANG. Kelemahan otot yang terjadi pada 75% - 80% pasien stroke menyebabkan terbatasnya aktivitas pasien stroke. Cara pengukuran kekuatan otot yang mudah digunakan di klinis adalah dengan hand-held dinamometer, sedangkan untuk mengukur kemampuan berjalan yang cukup efektif pada pasien stroke adalah uji jalan 2 menit. Telah banyak penelitian yang mendapatkan adanya hubungan antara kekuatan otot sisi paresis dengan kemampuan berjalan pada pasien stroke, namun belum ada yang menghubungkan antara kekuatan otot tersebut dengan uji jalan 2 menit. Tujuan penelitian ini untuk mengetahui korelasi antara kekuatan otot sisi paresis dengan kemampuan berjalan pada pasien stroke kronik yang diukur dngan uji jalan 2 menit dan mengetahui kelompok otot yang paling berpengaruh terhadap kemampuan berjalan tersebut.METODE. Pada 28 subyek penelitian yang memenuhi kriteria dan bersedia mengikuti penelitian dilakukan pengukuran kekuatan otot tungkai sisi paresis, yaitu otot ekstensor panggul, fleksor panggul, ekstensor lutut, fleksor lutut, dorsifleksor pergelangan kaki, plantarfleksor pergelangan kaki, dengan hand-held dinamometer, kemudian dilakukan uji jalan 2 menit. Data demografis dan klinis pasien dikumpulkan dan dicatat.HASIL. Diperoleh korelasi positif yang bermakna antara kekuatan otot tungkai sisi paresis yaitu otot ekstensor panggul, fleksor panggul, ekstensor lutut, fleksor lutut, dorsifleksor pergelangan kaki, dan plantarfleksor pergelangan kaki dengan jarak tempuh berjalan yang diuji dengan uji jalan 2 menit (r= 0,410 hingga r = 0,645) . Diperoleh korelasi positif yang bermakna antara kekuatan otot tungkai sisi paresis yaitu otot ekstensor panggul, fleksor panggul, ekstensor lutut, fleksor lutut, dorsifleksor pergelangan kaki, dan plantarfleksor pergelangan kaki dengan kecepatan berjalan yang diuji dengan uji jalan 2 menit (r= 0,409 hingga r = 0,641). Otot yang paling berpengaruh terhadap kemampuan berjalan pada pasien stroke kronik dengan nilai r tertinggi dan p terendah adalah otot plantarfleksor pergelangan kaki, diikuti dorsifleksor pergelangan kaki, fleksor panggul, fleksor lutut, ekstensor lutut, dan terakhir ekstensor panggul.KESIMPULAN. Terdapat korelasi positif antara kekuatan otot tungkai sisi paresis dengan kemampuan berjalan pada pasien stroke kronik, dengan otot yang paling berpengaruh terhadap kemampuan berjalan yaitu otot plantarfleksor pergelangan kaki.

---

ABSTRACTBACKGROUND. Muscle weakness that occurs in 75% - 80% of stroke patients causing limited activity of stroke patients. The easy way to measure muscle strength in clinical is by using a hand-held dynamometer, whereas the effective way to measure the ability to walk in stroke patients is using a 2-minute walk test. Previous studies said that there was relationship between muscle strength in paretic side with walking ability in stroke patients, but there is still no study about correlation between the muscle strength with a 2 minute walk test. The purpose of this study to determine the correlation between muscle strength of the lower extremity of the paretic side with walking ability in patients with chronic stroke using 2 minutes walk test, and determine which muscle groups that has the best correlation with the ability of walking.METHOD. There were 28 subjects who were eligible and willing to participate in the research. They got measurements of lower extremity muscle strength of the paretic side (hip extensor muscles, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, ankle plantarflexor) using hand-held dynamometer, then 2 minutes walk test. Patient demographic and clinical data were collected and recorded.THE RESULTS. There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with the length of 2-minute walk test (r = 0.410 - r = 0.645). There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with walking speed of the 2-minute walk test (r = 0.409 - r = 0,641). The muscles with the best correlation with the ability of walking in patients with chronic stroke are the muscles with the highest r and the lowest p, plantarflexor ankle muscles, followed by dorsiflexor ankle muscles, hip flexors muscles, knee flexors muscles, knee extensor muscles, and hip extensor muscles.CONCLUSION. There are positive correlation between the strength of the lower extremity muscles of the paretic side with walking ability in patients with chronic stroke, and the muscles with the best correlation with the ability of walking are plantarflexor ankle muscles. ;BACKGROUND. Muscle weakness that occurs in 75% - 80% of stroke patients causing limited activity of stroke patients. The easy way to measure muscle strength in clinical is by using a hand-held dynamometer, whereas the effective way to measure the ability to walk in stroke patients is using a 2-minute walk test. Previous studies said that there was relationship between muscle strength in paretic side with walking ability in stroke patients, but there is still no study about correlation between the muscle strength with a 2 minute walk test. The purpose of this study to determine the correlation between muscle strength of the lower extremity of the paretic side with walking ability in patients with chronic stroke using 2 minutes walk test, and determine which muscle groups that has the best correlation with the ability of walking.METHOD. There were 28 subjects who were eligible and willing to participate in the research. They got measurements of lower extremity muscle strength of the paretic side (hip extensor muscles, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, ankle plantarflexor) using hand-held dynamometer, then 2 minutes walk test. Patient demographic and clinical data were collected and recorded.THE RESULTS. There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with the length of 2-minute walk test (r = 0.410 - r = 0.645). There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with walking speed of the 2-minute walk test (r = 0.409 - r = 0,641). The muscles with the best correlation with the ability of walking in patients with chronic stroke are the muscles with the highest r and the lowest p, plantarflexor ankle muscles, followed by dorsiflexor ankle muscles, hip flexors muscles, knee flexors muscles, knee extensor muscles, and hip extensor muscles.CONCLUSION. There are positive correlation between the strength of the lower extremity muscles of the paretic side with walking ability in patients with chronic stroke, and the muscles with the best correlation with the ability of walking are plantarflexor ankle muscles. , BACKGROUND. Muscle weakness that occurs in 75% - 80% of stroke patients causing limited activity of stroke patients. The easy way to measure muscle strength in clinical is by using a hand-held dynamometer, whereas the effective way to measure the ability to walk in stroke patients is using a 2-minute walk test. Previous studies said that there was relationship between muscle strength in paretic side with walking ability in stroke patients, but there is still no study about correlation between the muscle strength with a 2 minute walk test. The purpose of this study to determine the correlation between muscle strength of the lower extremity of the paretic side with walking ability in patients with chronic stroke using 2 minutes walk test, and determine which muscle groups that has the best correlation with the ability of walking.METHOD. There were 28 subjects who were eligible and willing to participate in the research. They got measurements of lower extremity muscle strength of the paretic side (hip extensor muscles, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, ankle plantarflexor) using hand-held dynamometer, then 2 minutes walk test. Patient demographic and clinical data were collected and recorded.THE RESULTS. There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with the length of 2-minute walk test (r = 0.410 - r = 0.645). There are significant positive correlation between the strength of the lower extremity muscles of the paretic side (hip extensor, hip flexors, knee extensors, knee flexors, ankle dorsiflexor, and ankle plantarflexor muscles) with walking speed of the 2-minute walk test (r = 0.409 - r = 0,641). The muscles with the best correlation with the ability of walking in patients with chronic stroke are the muscles with the highest r and the lowest p, plantarflexor ankle muscles, followed by dorsiflexor ankle muscles, hip flexors muscles, knee flexors muscles, knee extensor muscles, and hip extensor muscles.CONCLUSION. There are positive correlation between the strength of the lower extremity muscles of the paretic side with walking ability in patients with chronic stroke, and the muscles with the best correlation with the ability of walking are plantarflexor ankle muscles. ]"

"Tujuan Kadar plasminogen activator inhibitor-1 (PAI-1) yang tinggi menyebabkan penurunan aktivitas sistem fibrinolisis. Saat ini kadar PAI-1 yang tinggi diketahui merupakan faktor risiko penyakit jantung iskemik tetapi pada penderita stroke iskemik hal ini masih belum jelas. Pada penelitian ini ingin diketahui hubungan antara kadar PAI-1 dengan stroke iskemik. Metode Dengan menggunakan desain kasus kontrol, kami melibatkan 38 subjek penderita stroke iskemik dan 38 subjek kontrol yang memenuhi kriteria penelitian. Kadar PAI-1 diperiksa dengan metode ELISA menggunakan reagen Asserachrom PAI-1 dari Stago. Hasil Kadar PAI-1 yang tinggi ditemukan lebih sering pada penderita stroke iskemik daripada subjek kontrol (21.1% vs. 7.9 % dengan OR 3.1; 95 % CI 0.757 ? 12.790). Analisa terhadap semua subjek yang diteliti menunjukkan adanya hubungan negatif yang lemah namun bermakna antara kadar PAI-1 dengan usia (r = - 0.4; P = 0.000). Kadar PAI-1 yang tinggi ditemukan lebih sering pada subjek berusia muda (40 ? 58 tahun) daripada subjek berusia lebih tua ( 60 ? 84 tahun) (20 vs. 9.8 %) (P = 0.004). Kesimpulan Dari hasil penelitian pendahuluan ini diduga ada hubungan antara kadar PAI-1 dengan stroke iskemik pada usia muda. Penelitan lebih lanjut dengan jumlah subjek yang lebih besar diperlukan untuk memastikan keadaan ini.

---

AbstractAim Recently, increased plasminogen activator inhibitor-1 (PAI-1) has been known a risk factor for ischemic heart disease. However, the association of increased PAI-1 level with ischemic stroke remains unclear. The aim of this study was to analyze the association of PAI-1 level with ischemic stroke. Methods By case control design we involved 38 ischemic stroke and 38 risky-matched control subjects who fulfilled the criteria. The PAI-1 level was determined by ELISA method using Asserachrom PAI-1 from Stago. Results High PAI-1 level was found more frequent in ischemic stroke subjects than in control subjects (21.1% vs. 7.9 % with OR 3.1; 95 % CI 0.757 ? 12.790). The analysis of all studied subjects showed that there was a weak negative correlation between PAI-1 level and age (r = -0.4; P = 0.000). High PAI-1 level was found more frequent in younger (40 ? 58 years old) than in the older subjects (60 ? 84 years old) (20% vs. 9.8 %) (p=0.004). Conclusion The result of this preliminary study suggested an association between PAI-1 level and ischemic stroke in younger age. Further study with larger subjects is recommended to confirm this association."

"Stroke merupakan kondisi emergency yang terjadi karena iskemi serebral, dengan penurunanaliran darah dan oksigen ke jaringan serebral yang dapat menyebabkan kerusakan otak yangpermanen bahkan sampai dengan kematian. Latar belakang dalam pengambilan kasusStroke dikarenakan terdapat 15 juta orang yang mengalami stroke setiap tahun danmerupakan penyebab kematian kedua diatas usia 60 tahun dan penyebab kematian kelimapada usia 15-59 tahun. Tujuan penelitian ini untuk mengetahui hubungan antara karakteristik,tingkat kecemasan dan ketergantungan dengan penerimaan diri pasien keterbatasan gerakakibat stroke. Hasil penelitian didapatkan terdapat hubungan karakteristik usia dan tingkatkecemasan dengan penerimaan diri pasien keterbatasan gerak akibat stroke. Hasil penelitian merekomendasikan Rumah Sakit umum sebagai pemberi layanan kesehatanyang berfokus pada pelayanan kesehatan fisik hendaknya juga meningkatkan layanankesehatan jiwa dalam memberika asuhan keperawatan yang komperhensif.

---

Stroke is an emergency condition that occured as the cerebral ischemic, with decreased inblood flow and oxygen to the cerebral tissues that can caused permanent brain damaged andeven up to death, basic in decision Stroke cased because there are 15 million people whosuffered stroke each year and the second leading caused of death above the age of 60 yearsand the fifth leading caused of death at the age of 15 59 years.

The purpose of this study todetermine the relationship between the characteristics, the level of anxiety and selfacceptancedependence with reduced mobility as stroke patients.

The results showed there arerelation characteristics of the age and level of anxiety with self acceptance limitation ofmotion in stroke patient.

The results of the study recommended to general hospital as thehealth care provider that focuses on physical health services should be also improving mentalhealth services in providing a comprehensive nursing care. "