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"T cell receptors covers biochemical, functional and genetic aspects of this key family of immunological molecules. It should be essential reading for all those interested in the TCR and its function in health and disease. It deals with the TCR protein, its functional interactions with the signal transduction machinery of the T cell and with the structure and organisation of the TCR genes. It is the only comprehensive volume on the TCR and is written by leaders in the field. Particularly useful is the tabulation and nomenclature of all the known TCR alpha and beta variable regions."

"Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International symposium on biochemical roles of eukaryotic cell surface macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell?matrix interaction."

"For the purposes of the present volume, cytokines are defined as secreted regulatory proteins that control the survival, growth, differentiation and effector function of tissue cells. Cytokines encompass those families of regulators variously known as growth factors, colony-stimulating factors, interleukins, lymphokines, monokines, and interferons. I have excluded most of the classical endocrine hormones because their general properties are different from those of the cytokines (see Table 1) and because they have been amply described in other texts. Nevertheless, there are no sharp boundaries that distinguish cytokines from other regulatory proteins and the selections in this book reflect my own bias."

"As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning.The entire illustration program has been greatly enhanced.Protein structures better illustrate structure?function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting ?What We Don?t Know,? introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system."

"Even the most experienced instructor can find teaching cell biology daunting, and most cell biology texts are bogged down in detail or background information. Lost in all the details are the more fascinating material and contemporary advances that represent this rapidly moving field. With so much to cover, creating a classroom around active learning may be difficult or nearly impossible. The Cell: A Molecular Approach endeavors to address those issues with succinct writing, incorporation of current research, a test bank that encourages critical thinking, and an active learning framework. With just enough detail for a one-semester, junior level course, the text presents fundamental concepts and current research, including chapters on genomics and transcriptional regulation and epigenetics, and new in-text boxed features on molecular medicine and key experiments. For instructors who want to flip their classrooms or just get students more engaged, The Cell: A Molecular Approach is the only cell biology text that is accompanied by an Active Learning Guide. This chapter-by-chapter playbook shows instructors how to create a dynamic learning environment with in-class exercises, clicker questions, and links to relevant media, animations, testing, and self-quizzing, all aligned with the new in-text learning objectives, wherever appropriate. This text provides the right level of detail, student engagement, and instructor support for the modern cell biology classroom"

"Describing in detail some of the key experimental findings, along with the original data and figures in the field, this text highlights information gained from cell research and uses it to illustrate the impact on current and future medical practice"

"Opening with a general introduction on chemokine function and chemokine receptor biology, the handbook goes on to cover the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including HIV/AIDS. The second half of the book systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners. Contributions in the first part of the book are mainly from academia, whereas the second part contains up-to-date reports from the pharmaceutical industry."