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Ditemukan 6164 dokumen yang sesuai dengan query
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Rosenbaum, Michael E
"Demonstrates how nutritional supplements can aid weight loss; boost sexual energy."
New York: Signet, 1989
613.282 ROS s
Buku Teks SO  Universitas Indonesia Library
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Heinerman, John
"Heinerman "reveals the wellness-enhancing properties of scores of vitamins and minerals, points you toward their best food sources, and gives you easy preparation tips and recipes." Includes information on hydrogen, oxygen and nitrogen"
New York: Prentice Hall, Paramus, N.J., 1998
613.286 HEI h
Buku Teks SO  Universitas Indonesia Library
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Murray, Michael T.
New York: Three Rivers Press, 1996
612.39 MUR e
Buku Teks SO  Universitas Indonesia Library
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White Plains: ConsumerLab.com, 2003
613.28 CON
Buku Teks SO  Universitas Indonesia Library
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White Plains: ConsumerLab.com, 2003
613.28 CON
Buku Teks SO  Universitas Indonesia Library
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Ria Andreinie
"Latar belakang: Indonesia dihadapkan pada masalah stunting yang cukup tinggi. Anak yang menderita stunting memiliki konsentrasi asam amino esensial yang lebih rendah. Mechanistic Target of Rapamycin Complex 1 (mTORC1) sebagai jalur utama regulasi pertumbuhan yang sensitif terhadap asam amino, mempromosikan sintesis protein melalui S6K1 dan 4EBP1. Penelitian ini bertujuan menganalisis keterlibatan asam amino esensial pada kadar mTORC1, S6K1, dan 4EBP1 dan korelasinya dengan kejadian stunting. Metode: Desain penelitian adalah kasus-kontrol. Anak berusia 6-24 bulan di Provinsi Sumatera Selatan diambil secara cluster random sampling berjumlah 137 orang. Pengumpulan data menggunakan kuesioner dan pengukuran antropometri. Pemeriksaan feses secara makroskopis dan mikroskopis, pemeriksaan darah dengan teknik LC-MS dan ELISA. Hasil: Terdapat perbedaan bermakna dalam hal usia anak, panjang badan lahir, BB/U, dan LK/U. Tidak ditemukan perbedaan makroskopis dan mikroskopis feses di antara kedua kelompok. Asam amino triptofan berbeda bermakna (p=0,004) dan berhubungan dengan kejadian stunting (p=0,045). Kadar mTORC1 dengan S6K1 dan 4EBP1 tidak berbeda pada kedua kelompok. Kadar mTORC1 tidak berhubungan dengan kejadian stunting. Kadar asam amino lisin berhubungan bermakna dengan kadar mTORC1 (p=0,003). Kadar mTORC1 berhubungan bermakna dengan kadar S6K1 dan 4EBP1 (masing-masing p<0,001). Simpulan: Asam amino esensial berimplikasi pada kejadian stunting dan kadar mTORC1, mTORC1 memengaruhi kadar S6K1 dan 4EBP1 anak.

Background: Indonesia is faced with a fairly high stunting problem. Children who suffer from stunting have lower concentrations of essential amino acids. The Mechanistic Target of Rapamycin Complex 1 (mTORC1) as the main pathway of growth regulation that is sensitive to amino acids, promotes protein synthesis through S6K1 and 4EBP1. This study aims to analyze the involvement of essential amino acids in mTORC1, S6K1, and 4EBP1 levels and their correlation with stunting. Methods: The study design was a case-control study. Children aged 6-24 months in South Sumatra Province were taken using cluster random sampling totaling 137 people. Data collection used questionnaires and anthropometric measurements. Macroscopic and microscopic examination of feces, and blood examination using LC-MS and ELISA techniques. Results: Significant differences were in child age, birth length, BB/A, and LK/A. There were no macroscopic and microscopic differences in feces between the two groups. Tryptophan amino acids were significantly different (p=0.004) and associated with stunting (p=0.045). mTORC1 levels with S6K1 and 4EBP1 were not different in both groups. mTORC1 levels were not associated with stunting. Lysine amino acid levels were significantly associated with mTORC1 levels (p=0.003). mTORC1 levels were significantly associated with S6K1 and 4EBP1 levels (each p<0.001). Conclusion: Essential amino acids are implicated in stunting and mTORC1 levels, and mTORC1 affects children's S6K1 and 4EBP1 levels."
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2025
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UI - Disertasi Membership  Universitas Indonesia Library
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Lingga Yudistira Abral
"Latar Belakang: Intrauterine Growth Restriction (IUGR) merupakan masalah yang sangat lazim pada kehamilan di dunia. Selain insufisiensi plasenta, penyebab lain adalah defisiensi nutrisi. Pada negara berkembang seperti Indonesia, konsumsi karbohidrat tetap tinggi sedangkan protein masih rendah. Asam amino sebagai komponen dasar dari setiap protein sangat berperan dalam pertumbuhan janin. Defisiensi asam amino pada akhirnya akan meningkatkan prevalensi IUGR. Namun, hanya ada beberapa penelitian tentang dampak masing-masing asam amino pada IUGR. Penelitian ini bertujuan untuk mengetahui kadar asam amino serum ibu pada IUGR dan kehamilan normal.
Metode: Penelitian observasional analitik dengan desain cross sectional dilakukan pada ibu hamil tunggal yang menjalani pemeriksaan kehamilan trimester III di RSUD dr. Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo, Indonesia selama periode September 2019 sampai Januari 2020. Subyek dengan IUGR atau kehamilan normal dimasukkan. Subyek dengan preeklamsia, diabetes gestasional, intervensi nutrisi, infeksi kronis, perokok, atau kelainan kongenital janin dieksklusikan. Berbagai kadar asam amino esensial dan non esensial ditentukan dari masing-masing subjek.
Hasil: Sebanyak 50 subjek (30 normal dan 20 IUGR) direkrut untuk penelitian. Tingkat asam amino ibu yang lebih tinggi pada kehamilan IUGR diamati pada valin, metionin, isoleusin, leusin, dan sistein (p <0,05) sedangkan tingkat yang lebih rendah diamati pada arginin, aspartat, dan serin (p <0,05).
Kesimpulan: Beberapa asam amino esensial kecuali arginin lebih tinggi pada IUGR, sedangkan asam amino non-esensial kecuali sistein lebih rendah pada IUGR.

Background: Intrauterine growth restriction (IUGR) is a highly prevalent problem on pregnancies in the world. Besides placental insufficiency, other etiology is nutritional deficiency. On developing countries such as Indonesia, consumption of carbohydrate remains high while protein remains low. Amino acid as the basic component of every protein highly contributes to fetal growth. Deficiency of amino acids would eventually increase the prevalence of IUGR. However, there is only a few studies on the impact of each amino acids on IUGR. This study aims to determine the level of maternal serum amino acids on IUGR and normal pregnancy.
Methods: An analytic observational study using cross sectional design was done on women with singleton pregnancy who was having third trimester antenatal care at dr. Cipto Mangunkusumo National General Hospital, Indonesia during the period of September 2019 to January 2020. Subjects with IUGR or normal pregnancy were included. Subjects with preeclampsia, gestational diabetes, nutrition intervention, chronic infections, smoker, or fetal congenital anomaly were excluded. Various essential and non-essential amino acids level were determined from each subject.
Results: A total of 50 subjects (30 normal and 20 IUGR) was recruited to the study. Higher maternal amino acids level in IUGR pregnancy was observed on valine, methionine, isoleucine, leucine, and cysteine (p < 0.05) while lower level was observed on arginine, aspartate, and serine (p < 0.05).
Conclusion: Some amino acids essential except arginine were higher in IUGR, whereas non-essential amino acids except cysteine was lower in IUGR.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2021
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UI - Tugas Akhir  Universitas Indonesia Library
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Dupont, Anton
"The statement contained in the motto cited above, made as early as the year 1906, still has lost nothing of its value for the present time. Although innumerable investigations have been carried out on proteins, and much insight was gained from this, a lot of problems connected with the proteins, remain to be solved. As is well known, proteins are found in nature in the animal and vegetable kingdoms. The differences between these two groups of proteins are situated in the number and the amount of the various acids present in these proteins.
Up to comparatively recent years, however, the knowledge of the requirement for the amino acids in the diet was limited to in-formation obtained with the young rat. This animal was able to grow when receiving only nine amino acids: namely histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine; and grew significantly better when arginine was also provided. These ten amino acids were called "essential" for the growing rat, the remaining amino acids were called "non essential". However, there was no implication that the dietetically non-essential amino acids are of little or no value. In spite of the cautions issued, there has been a general tendency to assume, that the above classification has a very broad application. The investigations made by Rose et all. (1,2,3,4,5), have revealed that for adult man only eight amino acids are essential, namely, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine. Moreover in these investigations, it was demonstrated, that only foods with sufficient caloric and nitrogen supply and adequate amounts of these eight amino acids simultaneously are able to main﷓ thin a nitrogen balance. This fact is of far reaching importance, because, from this it follows, that the nutritive value of a meal, with respect to the proteins, is determined by the total amount of essential amino acids - in the proper proportions - present in the constituents of the meal. In Indonesia, rice is the most important constituent of a meal. However rice contains such a small amount of some essential amino acids, that even larger use is not sufficient to meet the requirements of man. Therefore, other foods, which complete this shortage, must be used in combination with rice.
In general, in Indonesia, foods containing animal protein are relatively scarce; therefore, it is necessary to replace these with foods containing vegetable protein. An important source of plant protein is found in the soybean. As a general rule, the soybean yields fair crops, without asking too much care. Botanically, the soybean has been referred to as Glycine hispida (Moench) Max. Recent studies indicate that the correct botanical name should be Glycine max (L.) Merril according to international botanical rules (6).
The early history of the soybean, like that of most important food crops, is lost in obscurity. In the Far East story tellers for centuries have related, tales of the remarkable history of the soybean. Ancient Chinese literature reveals that the soybean was extensively cultivated and highly valued as a food. There it is said to be one of the grains planted by one of the gods of agriculture, named Hou Tsi. The first written record of the plant is contained in the books Pen Tsao Kong Mu, a materia medica written by Emperor Sheng Nung in 2838. B.C.
In many of the early writings advice of agricultural experts is given on soil preferences, proper time of planting, methods and rates of planting, the best varieties to plant under different conditions and for different uses, time to harvest, methods of storage, and utilization of the many varieties for different purposes. Some of this expert advice goes as far back as 2207 B.C. The soybean was included in the second class of drugs, and was regarded as having many medicinal virtues; it was regarded as a specific remedy for the propel functioning of the heart, and other organs."
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 1954
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UI - Disertasi Membership  Universitas Indonesia Library
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