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Abstrak :
This new title to the best-selling Lippincott's Illustrated Reviews series will present essential coverage of cell and molecular biology focusing on topics related to human health and disease. LIR Cell and Molecular Biology will include the popular features of the series: abundance of full-color, annotated illustrations; expanded outline format; chapter summaries; review questions; and case studies that link basic science to real-life clinical situations. The book can be used as a review text for a stand-alone cell biology course in medical, health professions, and upper-level undergraduate programs or in conjunction with LIR Biochemistry and/or LIR Physiology for integrated courses. A companion website features the fully searchable online text, an interactive Question Bank for students, and an Image Bank for instructors to use to create PowerPoint presentations.

Abstrak :
Over the past 40 years the field of molecular simulations has evolved from picosecond studies of isolated macromolecules in vacuum to studies of complex, chemically heterogeneous biological systems consisting of millions of atoms, with the simulation time scales spanning up to milliseconds. In Biomolecular Simulations: Methods and Protocols, expert researchers illustrate many of the methods commonly used in molecular modelling of biological systems, including methods for electronic structure calculations, classical molecular dynamics simulations and coarse-grained techniques. A selection of advanced techniques and recent methodological developments, which rarely find coverage in traditional textbooks, is also introduced. Written in the highly successful Methods in Molecular Biology series format, chapters include general introductions to well-established computational methodologies, applications to real-world biological systems, as well as practical tips and general protocols on carrying out biomolecular simulations. Special emphasis is placed on simulations of proteins, lipids, nucleic acids, and carbohydrates. Authoritative and practical, Biomolecular Simulations: Methods and Protocols seeks to aid scientists in further simulation studies of biological systems.

Abstrak :
Cell surface molecules are critically important in regulating cell structure and function. Recent advances on the functional role of cell surface molecules, particularly glycoconjugates are presented in this book. Comprising of 22 chapters from the 2011 International symposium on biochemical roles of eukaryotic cell surface macromolecules, it covers topics on the analysis of glycome, biophysical approaches to study cell surface molecules, glycoconjugate metabolism and its dysregulation, and molecular mechanisms involved in cell-cell and cell?matrix interaction.