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"Abstract

The Effect of Vitamin C and E Suplementations on Serum CReaetive Protein Level in Moderate-Severe Bum Patients.

To study the effect of vitamin C 1000 mg i.v and E 400 mg oral supplementation on serum c-reactive protein level as parameter of inflammation in bum patients.

This study was a one group pre post test that gave i. v 1000 mg vitamin C and ond 400 mg vitamin E supplementations to thirteen moderate-severe bum patients, with percentage of bum less than 60%, in bum unit Cipto Mangunkusumo Hospital. Data were collected using questionnaire, medical record, anthropometric measurement, dietary assessment using fol.lf consecutive days food record. Laboratory test for serum vitamin C, E and serum c-reactivc protein levels were evaluated before and after supplementations. Differences in mean values were assessed by Wilcoxon for the not normal distribution.

Results Among thirteen subjects, seven (53.80%) subjects were female, median of age 35 (18-55) years. Body mass index in most subjects (69.2%) were categorized as normal. The median percentages of bum injury 22 (5-57}%, and the frequency of severe bum was 61.50%, while the most cause of bum was flame (76.9%). Level of vitamin C after treatment was increased, but not significant. Level of vitamin E after treatment was significantly increased (!Pi),OI6). Level of CRP after supplementation significantly increased (!Pi).04).

Conclusion There was significantly reduced of level serum CRP after four days vitamin CI 000 mg i. v dan E 400 mg ond supplementations."

"ABSTRACT

Objective : To study the eH`ect of vitamin C 1000 mg i.v and E 400 mg oral supplementation on serum c-reactive protein level as parameter of inflammation in burn patients.

Methods: This study was a one group pre post test that gave i.v 1000 mg vitamin C and oral 400 mg vitamin E supplementations to thirteen moderate-severe burn patients, with percentage of burn less than 60%, in burn unit Cipto Mangunkusumo Hospital. Data were collected using questionnaire, medical record, anthropometric measurement, dietary assessment using four consecutive days food record. Laboratory test for serum vitamin C, E and serum c-reactive protein levels- were evaluated before and after supplementations. Differences in mean values were assessed by Wilcoxon for the not normal distribution.

Results: Among thirteen subjects, Seven (53.80%) Subjects were female, median of age 35 (18-55) years. Body mass index in most subjects (69.2%) were categorized as normal. The median percentages of burn injury 22 (5~57)%, and the frequency of severe burn was 6l.50%, while the most cause of burn was flame (76.9%). Level of vitamin C after treatment was increased, but not significant. Level of vitamin E after treatment was significantly increased (p=0,016). Level of CRP after supplementation significantly increased (p=0.04).

Conclussion: There was significantly reduced of level serum CRP after four days vitamin C1000 mg i.v dan E 400 mg oral supplementations."

"Penyajian serial kasus ini bertujuan untuk menganalisis dukungan nutrisi optimal pada penderita paru-paru obstruktif kronis. Pemilihan kasus berdasarkan karakteristik yang terdapat pada pasien paru-paru obstruktif kronis, yaitu usia lansia, sedang mengalami eksaserbasi akut, terdapat komplikasi dan faktor komorbid, serta malnutrisi (underweight atau obesitas), yang dirawat di rumah sakit. Kebutuhan energi ditentukan dengan menggunakan perhitungan rumus Harris Benedict dan dikalikan dengan faktor stres yang sesuai. Komposisi protein 1,2–1,7 gr/kg BB/hari, lemak 25-30%, dan karbohidrat 50–60%. Hasil analisis dari dua kasus didapatkan rerata pencapaian asupan lebih dari 90% kebutuhan energi basal pada hari terakhir perawatan, satu kasus mencapai 70%, dan satu kasus lagi telah mencapai mencapai 85% kebutuhan energi total. Hanya satu kasus yang mendapat suplementasi mikronutrien lengkap dosis RDA. Monitoring dan evaluasi yang diberikan meliputi klinis, imbang cairan, toleransi asupan, dan analisis asupan. Dukungan nutrisi yang optimal, pemberian edukasi serta motivasi kepada pasien dan keluarganya, akan memberikan toleransi asupan yang baik disertai perbaikan klinis.

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The aim of this serial case is to analyze optimal nutritional support in patients with COPD. The cases selection based on the characteristics of COPD patients, i.e. older age, acute exacerbation, complications, and comorbidity factor, as well as malnutrition (underweight or obese), who were hospitalized. Basal energy requirement were determined by the Harris-Benedict equotion and was multiplied by stress factor to calculate total energy requirement. Macronutriens compositions for protein ranged from 1.2 - 1.7 g/kg bw /day, lipids 25-30%, and carbohydrate 50-60% of total calories requirement. Intake analysis from two cases showed a mean intake over 90% of basal energy needs on the last day of treatment, one case reached 70%, and other case reached up to 85% of total energy needs. Only one case received full-dose micronutrient supplementation equal to RDA. Monitoring and evaluation included clinical status, fluid balance, intake tolerance, and intake analysis. Optimal nutritional support, provision of education and motivation to patients and their families, will enhanced intake tolerance along with clinical improvement."