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Abstrak :
Tujuan penelitian ini adalah untuk mengetahui distribusi chronotype dan prevalensi mengantuk berlebihan pada mahasiswa Fakultas Kedokteran Universitas Indonesia FKUI, serta mengetahui hubungan antara chronotype dan mengantuk berlebihan. Pada studi case-control ini, 149 orang mahasiswa mengisi 2 kuesioner yaitu Reduced Morningness-Eveningness Questionnaire dan Epworth Sleepiness Scale. Kemudian data dianalisis menggunakan Chi-square test. Tidak ditemukan hubungan bermakna antara chronotype dan mengantuk berlebihan. Kebanyakan mahasiswa tidak termasuk chronotype manapun 54.4, terdapat lebih banyak tipe pagi 26.2 dibanding tipe malam 19.5. Prevalensi mengantuk berlebihan sangat tinggi 57. Penelitian ini tidak menemukan hubungan bermakna antara chronotype dan mengantuk berlebihan. Juga didapatkan bahwa prevalensi mengantuk berlebihan sangat tinggi, terutama pada mahasiswa tingkat pertama dan berusia lebih muda. ......The objective of this study is to observe the distribution of chronotypes and prevalence of daytime sleepiness in medical students in Fakultas Kedokteran Universitas Indonesia FKUI, and to observe the relationship between chronotype and daytime sleepiness. In this case control study, 149 students answered two different questionnaires the Reduced Morningness Eveningness Questionnaire and Epworth Sleepiness Scale. The data was analyzed using a Chi square test. There was no statistical significance between chronotype and daytime sleepiness. Most students were neither chronotype 54.4, and there were more morning type 26.2 compared to evening type 19.5. The prevalence of excessive daytime sleepiness is high 57. This study did not find a significant association between chronotype and daytime sleepiness. This study also observed a higher prevalence of excessive daytime sleepiness, especially among the first year and younger students.

Abstrak :
ABSTRAK
Background: Community-acquired pneumonia is an acute infection of the lung parenchyma transmitted from the community with a high mortality rate. Predictors of mortality include the Pneumonia Severity Index (PSI) and CURB-65, and the biomarkers procalcitonin and D-dimers. Prealbumin (also known as transthyretin) is a biomarker for protein calorie malnutrition and has shown a positive correlation to negative patient outcomes in several different conditions. This study aims to study how prealbumin can be used as a predictor of mortality in CAP. Method: Articles were identified by searching 4 databases and screened for eligibility; 2 articles were eligible for this study. Assessment was done using the Quality in Prognosis Studies (QUIPS) tools and the Prognosis Critical Appraisal form. Result: The two articles assessed in this study have found that prealbumin is correlated with negative outcomes, particularly mortality. The studies have found that the patients who died had low serum prealbumin levels at admission. Conclusion: Serum prealbumin concentration is the preferred biomarker for protein calorie malnutrition as it is more sensitive compared to other biomarkers. There is a strong correlation between low serum prealbumin concentration upon admission with negative patient outcomes for patients with CAP. Further studies should include a wider range of subjects, specifically in age, and investigate the role of prealbumin as a predictor of malnutrition or inflammation and how it correlates to negative patient outcomes.