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Wahyu Edy Wibowo
Abstrak :
[Telah dilakukan penelitian dalam mengevaluasi pengaruh material homogen dan inhomogen pada teknik IMRT (Intensity Modulated Radiotherapy) menggunakan modalitas Fan Beam CT (FBCT) dan Cone Beam CT (CBCT) terhadap Gamma Index (GI). Perencanaan ulang dilakukan untuk 5 pasien kanker paru kanan pada modalitas FBCT dan CBCT menggunakan TPS Phillips Pinnacle energi foton 6 MV. Menggunakan Teknik IMRT 30 segmen, 50 segmen, dan 70 segmen untuk perencanan terapi. Calculation Grid Resolution (CGR) 0.2 cm dan 0.4 cm digunakan sebagai resolusi dalam perhitungan dosis. Serta kalibrasi bilangan CT (KBC) FBCT, CBCT, dan linear dipergunakan sebagai koreksi CT density number. Pengukuran plannar dose untuk evaluasi Gamma Index (DD 2% / DTA 2 mm, passing rate 90%) dilakukan pada SAD 100 cm dengan material homogen dan inhomogen pada kedalaman 1.5 cm, 5 cm, dan 10 cm. Didapatkan deviasi nilai rata-­‐rata GI antara CGR 0.2 cm dengan 0.4 cm material homogen modalitas FBCT dan CBCT berturut-­‐tutut ≤1.46% dan ≤ 1.13%. Serta deviasi pada material inhomogen sebesar ≤ 2.54% (FBCT) dan ≤ 1.74% (CBCT). Deviasi Nilai rata-­rata GI antara FBCT dengan CBCT dengan CGR 0.2 cm berturut-­turut ≤ 1.95% (homogen) dan ≤ 2.36% (inhomogen). Dan deviasi Nilai rata-­‐rata GI antara material homogen dan material ekuivalen homogen sebesar ≤ 0.80%. Dari hasil penelitian yang didapat, bahwa evaluasi Gamma Index dapat dipengaruhi oleh jumlah segmen, modalitas CT, kalibrasi bilangan CT, Calculation Grid Resolution, dan kedalaman material. ......These Studies have been carried out to evaluate the effect of a homogeneous and inhomogeneous material on IMRT Technique (Intensity Modulated Radiotherapy) using Fan Beam CT (FBCT) and Cone Beam CT (CBCT) for the Gamma Index (GI). The Phillips Pinnacle treatment plan was used to replan 5 patients on right side of lung cancer. Photon 6 MV was applied to this technique with 30 segments, 50 segments, and 70 segments, repectively. Using Calculation Grid Resolution (CGR) 0.2 cm and 0.4 cm for resolution in the calculation of the dose. As well as the calibration of CT numbers (CCN) FBCT, CBCT, and the linear density are used as a correction CT number. The planar measurement for the evaluation of Gamma Index (DD 2% / DTA 2 mm, the passing rate of 90%) carried out at 100 cm SAD with the homogeneous and inhomogeneous material at a depth of 1.5 cm, 5 cm, and 10 cm, respectively. We obtained deviation average value of GI between CGR 0.2 cm and 0.4 cm using the homogeneous material on FBCT and CBCT modality ≤1.46% and ≤ 1:13%, respectively. As well as the material inhomogeneous deviation of ≤ 2.54% (FBCT) and ≤ 1.74% (CBCT). The deviation of the average GI value between FBCT with CBCT with CGR 0.2 cm respectively ≤ 1.95% (homogeneous) and ≤ 2.36% (inhomogeneous). Finally, the deviation of the average GI value between homogeneous and equivalent of homogeneous material is ≤ 0.80%. From the results obtained, that the Gamma Index can be influenced by the number of segments, modalities of CT, calibration of CT numbers, calculation grid resolution and depth of material. , These Studies have been carried out to evaluate the effect of a homogeneous and inhomogeneous material on IMRT Technique (Intensity Modulated Radiotherapy) using Fan Beam CT (FBCT) and Cone Beam CT (CBCT) for the Gamma Index (GI). The Phillips Pinnacle treatment plan was used to replan 5 patients on right side of lung cancer. Photon 6 MV was applied to this technique with 30 segments, 50 segments, and 70 segments, repectively. Using Calculation Grid Resolution (CGR) 0.2 cm and 0.4 cm for resolution in the calculation of the dose. As well as the calibration of CT numbers (CCN) FBCT, CBCT, and the linear density are used as a correction CT number. The planar measurement for the evaluation of Gamma Index (DD 2% / DTA 2 mm, the passing rate of 90%) carried out at 100 cm SAD with the homogeneous and inhomogeneous material at a depth of 1.5 cm, 5 cm, and 10 cm, respectively. We obtained deviation average value of GI between CGR 0.2 cm and 0.4 cm using the homogeneous material on FBCT and CBCT modality ≤1.46% and ≤ 1:13%, respectively. As well as the material inhomogeneous deviation of ≤ 2.54% (FBCT) and ≤ 1.74% (CBCT). The deviation of the average GI value between FBCT with CBCT with CGR 0.2 cm respectively ≤ 1.95% (homogeneous) and ≤ 2.36% (inhomogeneous). Finally, the deviation of the average GI value between homogeneous and equivalent of homogeneous material is ≤ 0.80%. From the results obtained, that the Gamma Index can be influenced by the number of segments, modalities of CT, calibration of CT numbers, calculation grid resolution and depth of material. Key words : Calculation Grid Resolution, Calibration of CT Numbers, Cone]
Depok: Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Indonesia, 2016
T45207
UI - Tesis Membership  Universitas Indonesia Library
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Wahyu Edy Wibowo
Abstrak :
Berkendara dalam kegiatan operasional PT XYZ merupakan kejadian utama kecelakaan. Setiap tahun bahkan cenderung mengalamai kenaikan rate kecelakaan. Belajar dari kejadian kecelakaan berkendara di tahun 2016 dan 2017, PT XYZ berkewajiban untuk menurunkan tingkat rate kecelakaan, oleh karena itu di tahun 2018 diperkenalkan sebuah program Journey Management System (JMS) yang bertujuan untuk membentuk karakter pengemudi yang selamat guna mencapai penurunan jumlah kecelakaan berkendara di PT XYZ. Desain penelitian ini adalah survei menggunakan metode penelitian deskriptif dengan pendekatan semikuantitatif. Tujuannya adalah untuk mengetahui hubungan antara penerapan JMS dan jumlah kecelakaan sekaligus menilai perubahan perilaku pengemudi sebelum dan sesudah penerapan JMS ini. Aplikasi pengolahan data statistik (Statistical Product and Service Solution/ SPSS) dengan metode Correlation untuk mengetahui hubungan antara implementasi JMS dan perilaku mengemudi dan jumlah kecelakaan berkendara. Dari hasil penelitian ini disimpulkan bahwa JMS memiliki hubungan dengan perilaku mengemudi di PT XYZ, Akan tetapi JMS tidak memiliki hubungan dengan jumlah kecelakaan berkendara di PT XYZ. ......Driving in PT XYZ's operational activities is the main incident of accidents. Every year it even tends to experience an increase in the accident rate. Learning from the incidents of driving accidents in 2016 and 2017, PT XYZ is obliged to reduce the rate of accidents, therefore in 2018 a Journey Management System (JMS) program was introduced which aims to shape the character of safe drivers to achieve a reduction in the number of driving accidents in PT XYZ. The research design was a survey using descriptive research methods with a semi-quantitative approach. The aim is to determine the relationship between the implementation of the JMS and the number of accidents as well as to assess changes in driver behavior before and after the implementation of this JMS. Statistical data processing application (Statistical Product and Service Solution / SPSS) with the Correlation method to determine the relationship between JMS implementation and driving behavior and the number of driving accidents. From the results of this study it is concluded that JMS has a relationship with driving behavior at PT XYZ, however JMS has no relationship with the number of driving accidents at PT XYZ.
Depok: Fakultas Kesehatan Masyarakat Universitas Indonesia, 2020
T-pdf
UI - Tesis Membership  Universitas Indonesia Library
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Wahyu Edy Wibowo
Abstrak :
Telah dilakukan simulasi radioterapi paru-paru untuk verifikasi dosis kalkulasi TPS dengan pengukuran. fantom IMRT CIRS yang terdiri dari material jaringan lunak, paru-paru, dan tulang belakang digunakan sebagai objek dalam simulasi ini. Dosimeter yang digunakan dalam pengukuran adalah, bilik ionisasi Farmer tipe PTW 30013 dan NE 2571, serta Thermoluminisence Dosimeter (TLD). Fantom diradiasi menggunakan sinar-X 10 MV, ukuran lapangan 15 x 15 cm2 dengan 2 lapangan plane parallel metode Anterior-Posterior dan Posterior-Anterior (AP/PA) dan oblig Medio-Lateral dan Lateral-Medial (ML/LM) teknik SAD (Source to Axis Distance) 100 cm. Dosis pada jaringan lunak, paru-paru, dan tulang belakang dikalkulasi mengikuti protokol IAEA TRS 277 khusus untuk pengukuran dengan bilik ionisasi, sedangkan untuk pengukuran dengan TLD kalkulasi dosis pada ketiga medium menggunakan hasil kalibrasi. Dari 27 data deviasi antara hasil pengukuran dan kalkulasi TPS yang dievaluasi, untuk metode AP/PA diperoleh 18 data (66,67%) berada pada daerah antara -4 % sampai 6% dan 9 data (33,33%) berada diluarnya. Sedangkan untuk metode ML/LM, 20 data (74,07%) mempunyai deviasi berada dalam daerah ±6%, selebihnya 7 data (25,93%) memiliki deviasi lebih dari ±6%. Dalam penelitian ini, diperkirakan faktor koreksi ketidakhomogenan pada TPS kurang akurat terutama untuk jaringan paru.
A radiotherapy simulation of the lung for TPS verification dosage has been conducted by measurement. An IMRT CIRS phantom, that consisted of soft tissue, lung, and spine material, was used for this simulation. The dosimetry that were used in measurements are 30013 PTW Farmer-type and NE 2571 ionization chamber and also Thermoluminisence Dosimeter (TLD). Phantom was irradiated using a 10 MV X-ray with plane dimensions of 15 x 15 cm2 using 2 plane parallel field Anterior-Posterior method and oblique Lateral-Medial (ML/LM) technique where SAD (Source to Axis Distance) is 100 cm. Dosage at soft tissue, lung, and spine were calculated following the IAEA TRS 277 protocol specifically for ionization chamber measurement while measurements using TLD, dosage for those three areas was calculated using calibration result. Out of 27 deviation datas regarding the evaluation of measurements and TPS calculation, for AP/PA method 18 datas (66.67%) were between -4% and 6%, while 9 datas (33,33%) were beyond it. Whereas for ML/LM method, 20 data (74,07%) have deviation between ±6%, remainder 7 data (25,93%) deviation have more than ±6%. In this study it is estimated that inhomogeneity correction factor for the TPS is not accurate especially for lung tissue.
Depok: Universitas Indonesia, 2008
S28837
UI - Skripsi Open  Universitas Indonesia Library