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Abstrak :
[ABSTRAK
Preeklampsia berat merupakan salah satu penyebab kematian ibu di Indonesia. Di RSUD Dr. H. Abdul Moeloek, preeklampsia berat merupakan penyebab kematian ibu tertinggi (47,25%). Penelitian ini bertujuan untuk mengetahui hubungan prediktor preeklampsi berat (PEB)yang dinilai dari tekanan darah sistolik, tekanan darah diastolik, proteiunuria, kejang, sindrom HELLP dan hubungan jumlah prediktor PEB dengan kematian ibu di RSUD Dr. H. Abdul Moeloek tahun 2010- 2014. Desain penelitian yang digunakan kasus kontrol dengan jumlah sampel 60 kasus dan 120 kontrol. Sindrom HELLP meningkatkan kematian ibu OR (Odds Ratio) 12,5 (95% CI= 2,9-53,7), eklampsi OR 12,1 (95% CI= 3,8-38,6). Tekanan darah diastolik 110-119 OR 7,4 (95% CI=1,8-29,2), tekanan darah diastolik ≥120 mmHg OR 5,5 (95%CI 1,1-23,1) setelah dikontrol oleh usia ibu, gravida, usia kehamilan, jenis persalinan,pemberian diasepam, pendidikan, tempat tinggal pekerjaan.Prediktor PEB berjumlah 4 atau 5meningkatkan risiko kematian OR 90 (95%CI=13,7-591,3), prediktor berjumlah 3 OR16 (95%CI=3,9-66,7) dan prediktor berjumlah 2 OR6,3 (95% CI= 1,4-22,2). Meningkatkan pelaksanaan auditmaternal untuk mengkaji kasus kematian ibu akibat preeklampsia berat.

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ABSTRACT
Severe preeclampsia is one of the causes of maternal mortality in Indonesia. At Province public hospitalDr. H. Abdul Moeloek, Severe preeclampsia is the highest cause of maternal mortality (47,25%). This research aimed to know the relation of predictor severe preeclampsiaassessed by systolic blood pressure, diastolic blood pressure, proteiunuria, eclampsia and HELLP syndromeand total predictor severe preeclampsiawith maternal mortality at public hospital Dr. H. Abdul Moeloek in the year of 2010-2014. The design used case control by using 60 samples for case and 120 for controlers. HELLP syndrome increase risk of maternal mortality with OR (odds ratio) of 12.5 (95%CI= 2.90 to 53.72), eclampsia OR 12.1 (95% CI = 3.80 to 38.65), diastolic blood pressure 110-119 OR 7,4 (95% CI=1,8-29,2), diastolic blood pressure ≥120 mmHg OR 5,5 (95%CI 1,1-23,1) after controlled by maternal age, gravida, gestational age, type of delivery, giving diazepam, residence, employment and education.Predictorswhichconsists of 4or5increase risk of maternal mortalityOR90(95 % CI = 13.7 to 591.3), predictors totaling 3 OR 16(95 % CI = 3.9 to 66.7) and predictors 2 OR 6.3 (95% CI = 1.4 to 22.2).Improve maternal audit to assess the implementation of maternal deaths due to severe preeclampsia;Severe preeclampsia is one of the causes of maternal mortality in Indonesia. At Province public hospitalDr. H. Abdul Moeloek, Severe preeclampsia is the highest cause of maternal mortality (47,25%). This research aimed to know the relation of predictor severe preeclampsiaassessed by systolic blood pressure, diastolic blood pressure, proteiunuria, eclampsia and HELLP syndromeand total predictor severe preeclampsiawith maternal mortality at public hospital Dr. H. Abdul Moeloek in the year of 2010-2014. The design used case control by using 60 samples for case and 120 for controlers. HELLP syndrome increase risk of maternal mortality with OR (odds ratio) of 12.5 (95%CI= 2.90 to 53.72), eclampsia OR 12.1 (95% CI = 3.80 to 38.65), diastolic blood pressure 110-119 OR 7,4 (95% CI=1,8-29,2), diastolic blood pressure ≥120 mmHg OR 5,5 (95%CI 1,1-23,1) after controlled by maternal age, gravida, gestational age, type of delivery, giving diazepam, residence, employment and education.Predictorswhichconsists of 4or5increase risk of maternal mortalityOR90(95 % CI = 13.7 to 591.3), predictors totaling 3 OR 16(95 % CI = 3.9 to 66.7) and predictors 2 OR 6.3 (95% CI = 1.4 to 22.2).Improve maternal audit to assess the implementation of maternal deaths due to severe preeclampsia, Severe preeclampsia is one of the causes of maternal mortality in Indonesia. At Province public hospitalDr. H. Abdul Moeloek, Severe preeclampsia is the highest cause of maternal mortality (47,25%). This research aimed to know the relation of predictor severe preeclampsiaassessed by systolic blood pressure, diastolic blood pressure, proteiunuria, eclampsia and HELLP syndromeand total predictor severe preeclampsiawith maternal mortality at public hospital Dr. H. Abdul Moeloek in the year of 2010-2014. The design used case control by using 60 samples for case and 120 for controlers. HELLP syndrome increase risk of maternal mortality with OR (odds ratio) of 12.5 (95%CI= 2.90 to 53.72), eclampsia OR 12.1 (95% CI = 3.80 to 38.65), diastolic blood pressure 110-119 OR 7,4 (95% CI=1,8-29,2), diastolic blood pressure ≥120 mmHg OR 5,5 (95%CI 1,1-23,1) after controlled by maternal age, gravida, gestational age, type of delivery, giving diazepam, residence, employment and education.Predictorswhichconsists of 4or5increase risk of maternal mortalityOR90(95 % CI = 13.7 to 591.3), predictors totaling 3 OR 16(95 % CI = 3.9 to 66.7) and predictors 2 OR 6.3 (95% CI = 1.4 to 22.2).Improve maternal audit to assess the implementation of maternal deaths due to severe preeclampsia]

Abstrak :
Pre-eklampsia berat, salah satu penyebab utama kematian ibu di Indonesia dan di RSUD Dr. H. Abdul Moeloek Lampung, merupakan penyebab kematian ibu nomor satu (47,25%). Penelitian ini bertujuan untuk mengetahui hubungan prediktor pre-eklampsi berat (PEB) yang dinilai dari tekanan darah sistolik, tekanan darah diastolik, proteiunuria, eklampsia, sindrom hemolysis, elevated liver enzymes, low platelets count (HELLP) dengan kematian ibu di RSUD Dr. H. Abdul Moeloek. Penelitian ini menggunakan desain kasus kontrol dengan jumlah sampel 60 kasus dan 120 kontrol. Data diolah dari rekam medis rumah sakit selama periode lima tahun (2010 ? 2014). Hasil penelitian ini memperlihatkan bahwa sindrom HELLP memiliki risiko kematian ibu 12 kali lebih tinggi (95%CI 2,9 - 53,7) dan eklampsia memiliki risiko 12,1 kali lebih tinggi (95%CI 3,8 - 38,6). Tekanan darah diastolik 110 - 119 mmHg memiliki risiko 7,4 kali lebih tinggi (95%CI 1,8 - 29,2), tekanan darah diastolik ³ 120 mmHg memiliki risiko 5,5 kali lebih tinggi (95%CI 1,1 - 23,1), tekanan darah sistolik > 190 mmHg memiliki risiko 2,1 kali lebih tinggi (95%CI 0,5 - 7,4), tekanan darah sistolik 170 - 190 mmHg memiliki risiko 1,6 kali lebih tinggi (95%CI 0,5 ? 4,5), proteinuria +3 memiliki risiko 4,2 kali lebih tinggi (95%CI 0,3 - 27,4), proteinuria +4 memiliki risiko 3,2 kali lebih tinggi (95%CI 0,5 - 31,7) setelah dikontrol oleh usia ibu, gravida, usia kehamilan, metode persalinan, pemberian diasepam, pendidikan, tempat tinggal, dan pekerjaan. Oleh karena itu, perlu meningkatkan deteksi dini komplikasi kehamilan dan penanganan yang baik kasus preeklampsia untuk mencegah kematian ibu akibat eklampsia dan sindrom HELLP.

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Severe preeclampsia, one of main causes of maternal death in Indonesia and at Dr. H. Abdul Moeloek Lampung Public Hospital, is the leading cause Pre-eklampsia Berat dan Kematian Ibu Severe Preeclampsia and Maternal Death Nova Muhani*, Besral** of maternal death (47.25%). This study aimed to determine relation of severe preeclampsia predictor as assessed from systolic blood pressure, diastolic blood pressure, proteiunuria, eclampsia and HELLP syndrome with maternal death at Dr. H. Abdul Moeloek Public Hospital. This study used case control design with 60 cases and 120 control total of sample. Data was managed from hospital medical records during five years period (2010 - 2014). Results of study showed HELLP syndrome had risk of maternal death 12 times higher (95%CI 2.9 - 53.7) and eclampsia had the risk 12.1 times higher (95%CI 3.8 - 38.6). Then diastolic blood pressure 110 - 119 mmHg had the risk 7.4 times higher (95%CI 1.8 - 29.2), diastolic blood pressure ³ 120 mmHg had the risk 5.5 times higher (95%CI 1.1 - 23.1), sistolic blood pressure > 190 mmHg had the risk 2.1 times higher (95%CI 0.5 - 7.4), sistolic blood pressure 170 - 190 mmHg had the risk 1.6 times higher (95%CI 0.5 - 4.5), proteinuria +3 had the risk 4.2 times higher (95%CI 0.3 - 27.4), proteinuria +4 had the risk 3.2 times higher (95%CI 0.5 - 31.7) after controlled by maternal age, gravida, pregnancy age, delivery method, diazepam provision, education, domicile and employment. Therefore, it needs to improve early detection of pregnancy complication and good management of preeclampsia case to prevent maternal death due to eclampsia and HELLP syndrome.