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"ABSTRACTThe aim of this study is to determine, the comparison of absorption by aquatic plants Hydrilla verticillata and Water hyacinth (Eichhomia crassipes) of malathion insecticide residues in water and comparison of malathion concentrationin tissues of fish fed with of contaminated water plants(Water hyacinth) with tissuesof fish, which was not fedcontaminated water plant. The effect of heating the contaminatedfish tissue, on its level in tissues of rats that consume it.For the first experiment (aquarium filled with 3 litre of water +H. verticillata100 gr + Water hyacinth 100 gr + 20uci14C-labeled malathion); for the second experiment (the first aquarium filled with 3 litre of water + 30 tails of goldfish + 20 uci14C-labeled malathion; second aquarium filled with 3 litre of water + Water hyacinth 100 gr + 30 tail of goldfist + 20 uci 14C ?labeled malathion. For the third experiment (most of contaminated fish tissue in the secondexperiment was driedat room temperature and then given to 30 mice and partly heated and then given to another 30mice). Malathion levels were then analyzed by using a liquid scintillation counter LSC-753 (Aloka). The results of alltreatments were compared using the Student t-test. It can be concluded, H. verticillatawas more efficient compared tothe enceng gondok in absorbing the insecticide malathion residues in water; malathion concentration in the tissues offish fed Water hyacinth was higher than those of fish not fed Water hyacinth; contaminated fish tissue residues ofmalathion, although be heated, can not belowered significantly, levels in the tissue. "

"Penelitian ini bertujuan untuk mengetahui jalur (pathway) dari insektisida malathion dari lingkungan akuatik (air) ketumbuhan akuatik atau hewan akuatik di sekitarnya, kemudian dari hewan akuatik ke mammalia darat (tikus) denganmenggunakan malathion yang telah diberi label (malathion radioisotope 14C). Penelitian tingkat pertama, akan dicarijalur perjalanan malathion dari lingkungan perairan ke tumbuhan air (yaitu Hydrilla verticillata) dan hewan akuatik(yaitu ikan mas). Kemudian pada penelitian tingkat ke dua akan dilihat jalur perjalanan malathion dari hewan akuatik(ikan mas) ke mammalia darat (tikus). Penelitian tingkat ketiga, akan dipantau pengaruh negatif dari pencemaraninsektisida malathion 96 EC pada sayuran di Indonesia, terhadap organ tikus (hati dan otak). Hasil yang didapat darisemua hewan perlakuan dibandingkan dengan kontrol dengan menggunakan uji-t Student. Hasil penelitianmemperlihatkan bahwa residu insektisida malathion di perairan dapat diserap oleh tumbuhan air dan dapat memasukitubuh dan atau organ hewan akuatik atau melalui mata rantai makanan, dan masuk secara langsung melalui insang,sisik, kulit. Residu malathion juga dapat masuk ke dalam tubuh mammalia darat (tikus) melalui matarantai makanan,yaitu dengan konsumsi ikan atau tumbuhan air yang terkontaminasi. Penelitian ini juga membuktikan bahwa dosispencemaran insektisida malathion pada sayuran di Indonesia, bila dikonsumsi selama 60 hari berturut-turut dapatmenimbulkan kerusakan yang nyata pada hati, tetapi tidak secara nyata menimbulkan kerusakan pada otak tikus.Thisresearch was aimed to settle on the pathway of insecticide contamination in the aquatic environment forwarding towardaquatic plants and animals by using radioisotope 14C labelled malathion. Then by using the same labelled malathion, itspathway to the mammals, i.e. mice, was also determined. The first step of the research was aimed to detect the pathwayof malathion residues in water moving toward aquatic plants i.e. Hydrilla verticillata and aquatic animals i.e. fishes.Subsequently, in the second step of the research, the pathway of this labelled malathion from aquatic animals (fish) tomammals (mice). Then, in the third step of this research, the influence of polluting dose of malathion 96 EC, which wasfrequently found in vegetables in Indonesia, on the mammals? organ i.e. liver and brain of mice. All of the treatments?results were compared to the controls? using Student t-test. Analysis of the results showed that the residual insecticidecan be absorbed by the aquatic plans and then entered the fish body through food chain, and also through the gills, skin,scales. Furthermore, it was substantiated that the mammals obtained residual malathion through its food chain, that is,when the fishes were eaten by the mice or other mammals. The concentration of the insecticide observed, malathion,absorbed by water plants, fish organ and mice organ found to be different. This study also proved that the concentrationdose of malathion found in vegetables in Indonesia can cause abnormality in the livers of the mice, if it was takenconsecutively for 60 days. It was also shown in this study that the brains of the treated mice did not show anysignificant abnormality."