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Abstrak :
Ekstrak daun Garcinia hombroniana Pierre telah diketahui mengandung senyawa flavonoida, namun belum diketahui aktivitas antioksidan dan penghambatan aktivitas lipoksigenasenya. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dengan metode FRAP (Ferric Reducing Antioxidant Power) dan penghambatan aktivitas lipoksigenase dari ekstrak daun G. hombroniana menggunakan kontrol positif baikalein. Pada penelitian ini dilakukan juga penetapan kadar flavonoida total secara kuantitatif dengan metode kolorimetri AlCl3 pada ekstrak teraktif menggunakan kontrol positif kuersetin. Hasil uji menunjukkan bahwa ekstrak n-heksana, etil asetat dan metanol daun G. hombroniana Pierre memiliki aktivitas antioksidan dengan nilai EC50 berturut-turut yaitu 36,260; 2,969; dan 7,416 μg/mL dan dapat menghambat aktivitas lipoksigenase dengan nilai IC50 berturut-turut yaitu 2,052; 0,134; dan 1,314 μg/mL. Ekstrak etil asetat daun G. hombroniana Pierre memiliki aktivitas antioksidan dan penghambatan aktivitas lipoksigenase teraktif. Kadar flavonoida total ekstrak etil asetat daun G. hombroniana Pierre sebesar 42,004 mg QE/g sampel. Ekstrak daun Garcinia hombroniana Pierre memiliki aktivitas antioksidan dan dapat menghambat aktivitas lipoksigenase.

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Garcinia hombroniana Pierre leaves extract have been known to contain flavonoid compounds, but it has not been known yet for its antioxidant activity and inhibition of lipoxygenase activity. This study aims to determine antioxidant activity tested by using FRAP (Ferric Reducing Antioxidant Power) method and inhibition of lipoxygenase activity of G. Hombroniana leaves extract using baicalein as the positive control. Total flavonoid assay is also quantitatively done by AlCl3 colorimetric method on the most active extract using quercetin as the positive control. The test results showed that the n-hexane, ethyl acetate and methanol extract of G. hombroniana Pierre leaves have antioxidant activity which showed by EC50 value​​ consecutively are 36.260; 2.969; dan 7.416 μg/mL, and can inhibit lipoxygenase activity which showed by IC50 value consecutively are 2.052; 0.134; and 1.314 μg/mL. Ethyl acetate extract of G. hombroniana Pierre leaves has the most active antioxidant activity and inhibition of lipoxygenase activity. Total flavonoid content of ethyl acetate extract of G. hombroniana Pierre leaves is 42.004 mg QE/g sample. Garcinia hombroniana Pierre leaves extract has antioxidant activity and can inhibit lipoxygenase activity.

Abstrak :
ABSTRAK
Nama : Shinta MarlinProgram Studi : ApotekerJudul : Praktik Kerja Profesi di Apotek Atrika Periode Bulan Januari Tahun 2017 Apoteker memiliki peran penting dalam pelayanan kefarmasian di apotek. Praktik Kerja Profesi Apoteker di Apotek Atrika bertujuan untuk memahami tugas, fungsi dan peran manajerial apoteker di apotek, memberikan kesempatan bagi calon apoteker untuk beradaptasi dengan lingkungan kerja nyata di apotek, serta memahami sistem manajemen di Apotek Atrika. Praktik kerja profesi dilakukan selama satu bulan yang terdiri atas manajemen apotek dan pelayanan farmasi klinik, meliputi pelayanan swamedikasi, pelayanan resep dokter, dan pelayanan informasi obat. Pada pelaksanaan praktik kerja, terdapat tugas khusus berupa analisis rancangan klinik pratama kerjasama BPJS dengan waktu pelayanan kurang dari 24 jam dan apotek program rujuk balik.Kata kunci : Praktik Kerja Profesi, Apotek Atrika, ApotekerTugas umum : xii 36 halaman; 4 gambar; 1 tabel; 6 lampiranTugas khusus : v 19 halaman; 3 gambar; 6 tabel; 3 lampiranDaftar acuan tugas umum : 8 1997-2017 Daftar acuan tugas khusus : 10 2004-2015

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ABSTRACT
Name Shinta MarlinProgram Study ApotecharyTitle Internship at Apotek Atrika on January 2017 Pharmacist has an important role in pharmaceutical service in pharmacies. Pharmacist Profession Practice at Apotek Atrika aims to understand the duties, functions and managerial role of pharmacist in pharmacies, providing an opportunity for pharmacist to adapt to real working environment in pharmacies, as well as to understand the management system at Apotek Atrika. Pharmacist Profession Practice are undertaken for one month consisting of pharmacy management and clinical pharmacy services, including swamedication service, prescription service, and drug information service. In the implementation of profession practice, there is a special task in the form of analysis of pratama clinical design cooperation BPJS with service time less than 24 hours and pharmacy referral program. Keyword Internship, Apotek Atrika, ApotecharyGeneral assignment xii 36 pages 4 pictures 1 table 6 appendixSpecific assignment v 19 pages 3 pictures 6 tables 3 appendixBibliography of general assignment 8 1997 2017 Bibliography of specific assignment 10 2004 2015

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Nama : Shinta MarlinProgram Studi : ApotekerJudul : Praktik Kerja Profesi di Puskesmas Kecamatan Gambir Periode Bulan Februari Tahun 2017 Apoteker memiliki peran penting dalam pelayanan kefarmasian di puskesmas. Praktik Kerja Profesi Apoteker di Puskesmas Kecamatan Gambir bertujuan untuk memahami tugas, fungsi dan peran manajerial apoteker di puskesmas, memberikan kesempatan bagi calon apoteker untuk beradaptasi dengan lingkungan kerja nyata di puskesmas, serta memahami sistem manajemen di Puskesmas Kecamatan Gambir. Praktik kerja profesi dilakukan selama tiga minggu yang terdiri atas manajemen puskesmas dan pelayanan farmasi klinik. Pada pelaksanaan praktik kerja, terdapat tugas khusus berupa studi literatur tentang Amlodipin dan pembuatan leaflet terkait hipertensi. Kata kunci : Praktik Kerja Profesi, Puskesmas Kecamatan Gambir, ApotekerTugas umum : xii 41 halaman; 5 gambar; 1 tabel; 9 lampiranTugas khusus : iii 17 halaman; 1 gambar; 1 tabel; 1 lampiranDaftar acuan tugas umum : 5 2009-2017 Daftar acuan tugas khusus : 3 2006-2015

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ABSTRACT
Name Shinta MarlinProgram Study ApotecharyTitle Internship at Gambir Subdistrict Clinic on February 2017 Pharmacist has an important role in pharmaceutical service in pharmacies. The Pharmacist Profession Practice at Gambir Subdistrict Clinic aims to understand the duties, functions and managerial role of pharmacist in pharmacies, providing an opportunity for pharmacist to adapt to real working environment in pharmacies, as well as to understand the management system at Gambir Subdistrict Clinic. Professional work practices are undertaken for three weeks consisting of pharmacy management and clinical pharmacy services. In the implementation of work practices, there is a special task in the form of a study literature on Amlodipine and the manufacture of leaflet related to hypertension. Keyword Internship, Gambir Subdistrict Clinic, ApotecharyGeneral assignment xii 41 pages 5 pictures 1 table 9 appendixSpecific assignment iii 17 pages 1 pictures 1 table 1appendixBibliography of general assignment 5 2009 2017 Bibliography of specific assignment 3 2006 2015

Abstrak :
ABSTRAK
Nama : Shinta MarlinProgram Studi : ApotekerJudul : Praktik Kerja Profesi di RSUPN Dr. Cipto Mangunkusumo Periode Bulan April - Juni Tahun 2017 Apoteker memiliki peran penting dalam pelayanan kefarmasian di rumah sakit. Praktik Kerja Profesi Apoteker di RSUPN Dr. Cipto Mangunkusumo bertujuan untuk memahami tugas, fungsi dan peran manajerial apoteker di rumah sakit, memberikan kesempatan bagi calon apoteker untuk beradaptasi dengan lingkungan kerja nyata di rumah sakit, serta memahami sistem manajemen di RSUPN Dr. Cipto Mangunkusumo. Praktik kerja profesi dilakukan selama dua bulan yang terdiri atas manajemen rumah sakit dan pelayanan farmasi klinik. Pada pelaksanaan praktik kerja, terdapat tugas khusus berupa identifikasi sediaan farmasi sound alike dan analisa kesalahan pengobatan untuk meningkatkan keselamatan pasien di RSUPN Dr. Cipto Mangunkusumo. Kata kunci : Praktik Kerja Profesi, RSUPN Dr. Cipto Mangunkusumo, ApotekerTugas umum : xii 47 halaman; 2 tabel; 1 lampiranTugas khusus : iii 15 halaman; 1 gambar; 3 lampiranDaftar acuan tugas umum : 7 2009-2017 Daftar acuan tugas khusus : 4 2001-2017

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ABSTRACT
Name Shinta MarlinProgram Study ApotecharyTitle Internship at Dr. Cipto Mangunkusumo Hospital on April June 2017 Pharmacist has an important role in pharmaceutical service in pharmacies. The Pharmacist Profession Practice at Dr. Cipto Mangunkusumo Hospital aims to understand the duties, functions and managerial role of pharmacist in pharmacies, providing an opportunity for pharmacist to adapt to real working environment in pharmacies, as well as to understand the management system at Dr. Cipto Mangunkusumo Hospital. Professional work practices are undertaken for two months consisting of pharmacy management and clinical pharmacy services. In the implementation of work practices, there is a special task in the form of identification of sound alike pharmaceutical preparation and medication error analysis to improve patient safety at Dr. Cipto Mangunkusumo hospital. Keyword Internship, Dr. Cipto Mangunkusumo Hospital, ApotecharyGeneral assignment xii 47 pages 2 tables 1 appendixSpecific assignment iii 15 pages 1 picture 3 appendixBibliography of general assignment 7 2009 2017 Bibliography of specific assignment 4 2001 2017