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Sidharta Kusuma Manggala
"[Latar Belakang: Posisi pasien selama tindakan anestesia spinal menentukan keberhasilan penempatan jarum spinal. Traditional sitting position (TSP) merupakan posisi standar untuk anestesia spinal, namun angka keberhasilannya masih cukup rendah. Crossed leg sitting position (CLSP) merupakan salah satu posisi alternatif dalam anestesia spinal yang memiliki kelebihan berupa derajat fleksi lumbal yang lebih besar. Penelitian ini bertujuan untuk membandingkan CLSP dan TSP terhadap keberhasilan penempatan jarum spinal pada pasien bedah urologi.
Metode: Penelitian ini adalah uji klinik acak tidak tersamar terhadap pasien yang menjalani anestesia spinal untuk prosedur urologi pada bulan Maret-April 2015 di RSUPN dr. Cipto Mangunkusumo. Setelah mendapatkan persetujuan izin etik dari Komite Etik Penelitian Kesehatan FKUI-RSCM, sebanyak 138 subjek dialokasikan ke dalam dua kelompok posisi penusukan jarum spinal yaitu kelompok CLSP dan TSP. Proporsi keberhasilan penempatan jarum spinal di rongga subarakhnoid, kemudahan perabaan landmark, dan jumlah needle-bone contact pada kedua kelompok kemudian dinilai.
Hasil: Enam subjek masuk kriteria pengeluaran berupa kegagalan penempatan jarum spinal setelah lebih dari sembilan kali percobaan. Tersisa 132 subjek, 67 subjek pada kelompok CLSP dan 65 subjek pada kelompok TSP, yang berhasil menyelesaikan penelitian. Keberhasilan penempatan jarum spinal secara one shot pada kelompok CLSP dan TSP tidak berbeda bermakna (64.2% vs 53.8%, p=0.227). Kemudahan perabaan landmark pada kelompok CLSP berbeda bermakna dengan TSP (94% vs 75%, p=0.003). Jumlah needle-bone contact pada kedua kelompok tidak berbeda bermakna (p=0.337).
Simpulan: Keberhasilan penempatan jarum spinal pada kelompok CLSP tidak berbeda bermakna dibandingkan dengan keberhasilan penempatan jarum spinal pada kelompok TSP pada pasien bedah urologi.;Background: Patient position during spinal anesthesia plays a major role in determining the success of spinal needle insertion to subarachnoid space. Traditional sitting position (TSP) is a standard position for spinal anesthesia, but the success rate for spinal anesthesia in TSP is still quite low. Crossed leg sitting position (CLSP) is one of the alternative positions in spinal anesthesia, which can increase the degree of lumbar flexion. This study aimed to compare CLSP and TSP to the successful insertion of spinal needle in urologic surgery patients.
Methods: This study was a non-blinded randomized controlled trial in patients undergoing spinal anesthesia for urologic procedures between March-April 2015 in RSUPN dr. Cipto Mangunkusumo. After obtaining approval from FKUI-RSCM Ethical Committee, 138 subjects were allocated into two groups, CLSP group and TSP group. The proportion of successful spinal needle insertion to the subarachnoid space, ease of landmark palpation, and the number of needle-bone contact in both groups were then analyzed and assessed.
Result: Six subjects met dropout criteria, which was failure of obtaining successful spinal needle insertion after nine consecutive redirections. The remaining 132 subjects, 67 subjects in the CLSP group and 65 subjects in TSP group, successfully completed the study. The proportion of successful spinal needle insertion in a one-time shot, was not significantly different between CLSP and TSP group (64.2% vs. 53.8%, p = 0227). Ease of landmark palpation in CLSP group was significantly different with TSP group (94% vs. 75%, p = 0.003). The number of needle-bone contact in both groups was not significantly different (p = 0337).
Conclusion: The proportion of successful spinal needle insertion in CLSP group was not significantly different compared to TSP group for urologic surgery patients.;Background: Patient position during spinal anesthesia plays a major role in determining the success of spinal needle insertion to subarachnoid space. Traditional sitting position (TSP) is a standard position for spinal anesthesia, but the success rate for spinal anesthesia in TSP is still quite low. Crossed leg sitting position (CLSP) is one of the alternative positions in spinal anesthesia, which can increase the degree of lumbar flexion. This study aimed to compare CLSP and TSP to the successful insertion of spinal needle in urologic surgery patients.
Methods: This study was a non-blinded randomized controlled trial in patients undergoing spinal anesthesia for urologic procedures between March-April 2015 in RSUPN dr. Cipto Mangunkusumo. After obtaining approval from FKUI-RSCM Ethical Committee, 138 subjects were allocated into two groups, CLSP group and TSP group. The proportion of successful spinal needle insertion to the subarachnoid space, ease of landmark palpation, and the number of needle-bone contact in both groups were then analyzed and assessed.
Result: Six subjects met dropout criteria, which was failure of obtaining successful spinal needle insertion after nine consecutive redirections. The remaining 132 subjects, 67 subjects in the CLSP group and 65 subjects in TSP group, successfully completed the study. The proportion of successful spinal needle insertion in a one-time shot, was not significantly different between CLSP and TSP group (64.2% vs. 53.8%, p = 0227). Ease of landmark palpation in CLSP group was significantly different with TSP group (94% vs. 75%, p = 0.003). The number of needle-bone contact in both groups was not significantly different (p = 0337).
Conclusion: The proportion of successful spinal needle insertion in CLSP group was not significantly different compared to TSP group for urologic surgery patients., Background: Patient position during spinal anesthesia plays a major role in determining the success of spinal needle insertion to subarachnoid space. Traditional sitting position (TSP) is a standard position for spinal anesthesia, but the success rate for spinal anesthesia in TSP is still quite low. Crossed leg sitting position (CLSP) is one of the alternative positions in spinal anesthesia, which can increase the degree of lumbar flexion. This study aimed to compare CLSP and TSP to the successful insertion of spinal needle in urologic surgery patients.
Methods: This study was a non-blinded randomized controlled trial in patients undergoing spinal anesthesia for urologic procedures between March-April 2015 in RSUPN dr. Cipto Mangunkusumo. After obtaining approval from FKUI-RSCM Ethical Committee, 138 subjects were allocated into two groups, CLSP group and TSP group. The proportion of successful spinal needle insertion to the subarachnoid space, ease of landmark palpation, and the number of needle-bone contact in both groups were then analyzed and assessed.
Result: Six subjects met dropout criteria, which was failure of obtaining successful spinal needle insertion after nine consecutive redirections. The remaining 132 subjects, 67 subjects in the CLSP group and 65 subjects in TSP group, successfully completed the study. The proportion of successful spinal needle insertion in a one-time shot, was not significantly different between CLSP and TSP group (64.2% vs. 53.8%, p = 0227). Ease of landmark palpation in CLSP group was significantly different with TSP group (94% vs. 75%, p = 0.003). The number of needle-bone contact in both groups was not significantly different (p = 0337).
Conclusion: The proportion of successful spinal needle insertion in CLSP group was not significantly different compared to TSP group for urologic surgery patients.]"
Fakultas Kedokteran Universitas Indonesia, 2015
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UI - Tugas Akhir  Universitas Indonesia Library
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Sidharta Kusuma Manggala
"Pembedahan abdomen atas berkaitan disfungsi diafragma. Disfungsi diafragma merupakan penyebab PPC (postoperative pulmonary complication). Terapi oksigen konvensional (TOK) merupakan terapi standar pada pasien pasca pembedahan abdomen atas. Terapi HFNC (high-flow nasal cannula) memiliki berbagai mekanisme yang berbeda dengan TOK dan dipikirkan dapat membantu fungsi diafragma pascapembedahan abdomen atas. Studi ini bertujuan untuk membandingkan kemampuan HFNC terhadap TOK dalam mempertahankan fungsi diafragma pascapembedahan abdomen atas. Studi ini dilakukan di RSUPN Dr. Cipto Mangunkusumo dari November 2018 – September 2019. Tujuh puluh satu pasien dibagi secara acak menjadi dua kelompok: kelompok TOK dan HFNC. Enam puluh enam pasien mendapat intervensi setelah ekstubasi di ICU (intensive care unit). Seluruh subjek dilakukan pencatatan nilai DTF (diaphragm thickening fraction) menggunakan ultrasonografi, ΔTIV (perubahan tidal impedance variance), ΔEELI-G dan ΔEELI-ROI (perubahan end expiratory lung impedance global dan region of interest) menggunakan EIT (electrical impedance tomography), PaO2 dan PaCO2 (tekanan parsial oksigen dan karbon dioksida arteri) secara berkala pada dua seri. Efek samping dan keluhan yang muncul dicatat dan ditatalaksana. Total 66 subjek disertakan dalam bivariat menggunakan t-test dan mann whitney, sedangkan analisis tren menggunakan general linear model atau generalized estimating equation. Durasi ventilasi mekanik di ICU, persentase prediksi mortalitas dan skor P-POSSUM antara kedua kelompok berbeda signifikan (p=0,003; 0,001; dan 0,019, secara berurutan). Tidak ada perbedaan tren yang ditemukan antarkelompok pada seri pertama parameter DTF, ΔTIV, ΔEELI-G, ΔEELI-ROI dan PaCO2 (p=0,951; 0,100; 0,935; 0,446; dan 0,705, secara berurutan) maupun pada seri kedua (p=0,556; 0,091; 0,429; 0,423; dan 0,687, secara berurutan). Tren PaO2 pada seri pertama dan kedua berbeda sangat signifikan (p<0,001) karena protokol pengaturan fraksi oksigen yang lebih tinggi pada kelompok TOK. Penggunaan HFNC tidak lebih baik daripada TOK dalam membantu mempertahankan fungsi diafragma pascapembedahan abdomen atas.

Upper abdominal surgery is related to diaphragmatic dysfunction. Diaphragmatic dysfunction is the main factors causing postoperative pulmonary complication (PPC). Conventional oxygen therapy (TOK) in the form of nasal cannula, is a standard therapy in post upper abdominal surgery patients. High-flow nasal cannula (HFNC) therapy has a variety of mechanisms that differ from TOK and is thought to be able to maintain diaphragm function in post upper abdominal surgery patients. This study aims to compare the ability of HFNC vs TOK in maintaining diaphragm function for post upper abdominal surgery patients. This study was conducted at RSUPN dr. Cipto Mangunkusumo from November 2018 - September 2019. Seventy-one patients were randomly divided into two groups: TOK and HFNC groups. Sixty-six patients received intervention after extubation in the intensive care unit (ICU). This given data were all collected periodically in 2 series; diaphragm thickening fraction (DTF) values using ultrasonography, changes in tidal impedance variance (ΔTIV), changes in global end expiratory lung impedance and region of interest (ΔEELI-G and ΔEELI-ROI) using electrical impedance tomography, arterial oxygen and carbon dioxide partial pressure (PaO2 and PaCO2). Side effects and complaints that arise were collected and managed. A total of 66 subjects were included in the bivariate using t-test and mann whitney test, while trends were analyzed by general linear models or generalized estimating equations. The baseline characteristics of mechanical ventilation duration in the ICU, the predicted mortality rate and P-POSSUM score between the two groups were significantly different (p = 0.003; 0.001; and 0.019, respectively). No trend differences were found between groups in the first series of DTF, ΔTIV, ΔEELI-G, ΔEELI-ROI and PaCO2 parameters (p = 0.951; 0.100; 0.935; 0.446; and 0.705, respectively) and in the second series (p = 0.556, 0.091, 0.429, 0.423 and 0.687, respectively). The PaO2 trends in the first and second series differed very significantly (p<0.001) due to the higher oxygen fraction regulation protocol in the COT group. The use of HFNC is no better than COT in maintaining diaphragm function for post upper abdominal surgery patients.
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Jakarta: Fakultas Kedokteran Universitas Indonesia, 2020
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UI - Tugas Akhir  Universitas Indonesia Library