Ditemukan 1 dokumen yang sesuai dengan query
Silman E.
"The aim of this study was to investigate the increase in neutrophil count and the decrease in both phagocytosis and neutrophil oxidative burst (formation of radical oxygen) among type 2 diabetes mellitus (DM) patients and the normal range of phagocytosis function and oxidative burst in neutrophil from Non-DM control subjects. The aim of this study is also to investigate the factors that influence neutrophil count, phagocytosis function and neutrophil oxidative burst among type 2 diabetes mellitus (DM) patients. The examination was conducted using a flow cytometry. The study subjects were 142 type 2 DM patients and 65 Non-DM control subjects. Statistical analysis was performed using the Mann Whitney test and linear regression analysis. The results of this study indicated that there is impaired neutrophil function among type 2 DM patients. The results of this study also showed a correlation between Hemoglobin level, age, platelet count, and SGPT vs. neutrophil phagocytosis function, as well as a correlation between HDL cholesterol and (fMLP-stimulated) neutrophil oxidative burst. The study also showed a correlation between sex and stroke and (S. sureus-stimulated) neutrophil radical oxygen formation, a correlation between neutrophil count and platelet count, a correlation offibAlc and fasting blood glucose level and (fMLP-stimulated) neutrophil radical oxygen formation. In a multivariate analysis, when adjusted to age and sex, there was a correlation between triglyceride and (baseline) neutrophil radical oxygen formation and between HDL cholesterol and (fMLP-stimulated) neutrophil radical oxygen formation."
2003
AMIN-XXXV-4-OktDes2003-184
Artikel Jurnal Universitas Indonesia Library