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"Seorang apoteker yang profesional harus mampu menerapkan ilmu pengetahuan yang telah diperoleh selama masa studi dalam melaksanakan pekerjaan kefarmasian. Sebagai upaya untuk meningkatkan pengetahuan dan keterampilan calon apoteker mengenai peran, fungsi, dan tanggung jawab apoteker serta mendapatkan gambaran pekerjaan kefarmasian, calon apoteker perlu melaksanakan Praktik Kerja Profesi Apoteker terlebih dahulu sebelum memasuki dunia kerja. Praktik Kerja Profesi Apoteker dilakukan di Apotek Roxy Jatikramat pada periode Januari 2022, PT. CKD OTTO Pharmaceuticals pada periode Maret – Mei 2022, dan Puskesmas Kecamatan Pasar Minggu pada periode Mei 2022. Setelah pelaksanaan Praktik Kerja Profesi Apoteker di apotek, industri farmasi, dan puskesmas tersebut, calon apoteker diharapkan dapat memiliki wawasan, pengetahuan, keterampilan, dan pengalaman yang cukup sehingga siap untuk memasuki dunia kerja sebagai apoteker yang kompeten dan profesional.

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A professional pharmacist must be able to apply the knowledge that has been obtained during the study period in carrying out pharmaceutical work. As an effort to improve the knowledge and skills of prospective pharmacists regarding the roles, functions, and responsibilities of pharmacists as well as to get an overview of pharmaceutical work, prospective pharmacists need to carry out the Pharmacist Professional Work Practice before entering the working world. The Pharmacist Professional Work Practice was carried out at the Roxy Jatikramat Pharmacy in the period January 2022, PT. CKD OTTO Pharmaceuticals in the period March – May 2022, and Pasar Minggu Public Medical Center in the period May 2022. After the implementation of the Pharmacist Professional Work Practice in pharmacy, pharmaceutical industry, and public medical center, prospective pharmacists are expected to have sufficient insight, knowledge, skills, and experience so that they are ready to enter the working world as competent and professional pharmacists."

"Hiperglikemia menginduksi pembentukan spesies oksigen reaktif (ROS) yang dapat meningkatkan stres oksidatif pada patogenesis diabetes nefropati. Ekstrak etanol kulit batang pulosari (Alyxia reinwardtii) diketahui mengandung pulosariosida, skopoletin, flavonoid, alkaloid, tanin, dan saponin yang memiliki efek antidiabetes dan antioksidan. Penelitian ini dilakukan untuk mengetahui efek ekstrak etanol kulit batang pulosari pada tikus diabetes yang diinduksi oleh pakan tinggi lemak dan streptozotocin dosis rendah. Pada penelitian ini, 24 ekor tikus jantan galur Wistar dibagi menjadi enam kelompok (n = 4), yaitu kelompok normal (CMC Na 0,5%), kelompok negatif (induksi + CMC Na 0,5%), kelompok positif (induksi + Metformin 90 mg/200 g BB), kelompok dosis 1 (induksi + ekstrak 30 mg/200 g BB), dosis 2 (induksi + ekstrak 60 mg/200 g BB), dan dosis 3 (induksi + ekstrak 120 mg/200 g BB). Tikus diinduksi dengan pemberian pakan tinggi lemak yang mengandung 50% pakan standar, 20% tallow, 20% sukrosa, dan 10% mentega selama 28 hari. Kemudian, diberi injeksi streptozotocin 40 mg/kg BB dan nikotinamid 110 mg/kg BB sebanyak dua kali. Setelah kadar glukosa darah mencapai ≥ 280 mg/dL dan stabil selama 3 hari, dilanjutkan dengan pemberian ekstrak selama 21 hari. Parameter kreatinin, urea, 8-OHdG, dan MDA diukur saat sebelum dan sesudah pemberian ekstrak. Kadar kreatinin dan urea diukur menggunakan spektrofotometer UVVis, sedangkan kadar 8-OHdG dan MDA diukur menggunakan ELISA. Ekstrak pulosari secara signifikan dapat menurunkan kadar kreatinin, urea, 8-OHdG, dan MDA (p < 0,05) dan kemampuannya serupa dengan metformin.

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Hyperglycemia induces the formation of reactive oxygen species (ROS) which can increase oxidative stress in the pathogenesis of diabetic nephropathy. The ethanol extract of pulosari (Alyxia reinwardtii) bark is known to contain pulosarioside, scopoletin, flavonoids, alkaloids, tannins, and saponins which have antidiabetic and antioxidant effects. This study was conducted to determine the effect of pulosari bark ethanol extract on diabetic rats induced by high-fat diet and low-dose streptozotocin. In this study, 24 male Wistar rats were divided into six groups (n = 4), namely the normal group (CMC Na 0.5%), negative group (induction + CMC Na 0.5%), positive group (induction + Metformin 90 mg/200 g BW), dose group 1 (induction + extract 30 mg/200 g BW), dose 2 (induction + extract 60 mg/200 g BW), and dose 3 (induction + extract 120 mg/200 g BW). Rats were induced by feeding high-fat diet containing 50% standar feed, 20% tallow, 20% sucrose, and 10% butter for 28 days. Then, given injection of streptozotocin 40 mg/kg BW and nicotinamide 110 mg/kg BW twice. After the blood glucose level reached ≥ 280 mg/dL and was stable for 3 days, then the extract is given for 21 days. Creatinine, urea, 8-OHdG, and MDA parameters were measured before and after administration of the extract. Creatinine and urea levels were measured using UV-Vis spectrophotometer, while 8-OHdG and MDA levels were measured using ELISA. Pulosari extract significantly reduced creatinine, urea, 8-OHdG, and MDA levels (p < 0.05) and its ability is similar to metformin. "