Hasil Pencarian  ::  Simpan CSV :: Kembali

"Di Indonesia, pengembangan produksi braket ortodonti dalam negeri sedang dikerjakan dan dibutuhkan studi lebih lanjut untuk mengetahui desain rumus bangun geometri dasar braket yang memiliki retensi terbaik. Braket ortodonti metal dapat melekat pada gigi mengandalkan retensi mekanis pada dasar braket. Analisis finite element suatu analisis dengan menggunakan model tiga dimensi untuk mempelajari dan menilai distribusi stress yang terjadi akibat aplikasi gaya geser dengan besaran dan arah tertentu. Letak konsentrasi stress yang besar diprediksi berisiko terjadi deformitas atau kegagalan. Penelitian ini menggunakan tiga jenis braket ortodonti metal insisif pertama rahang atas dengan tipe dasar braket non mesh yang ada di pasaran. Pembentukan model tiga dimensi berupa gigi insisif pertama rahang atas dengan blok tulang, tiga tipe braket, dan adhesif ortodonti. Proses simulasi dengan aplikasi gaya geser mesio-distal dan serviko-insisal sebesar 1 N. Hasil analisis finite element menunjukkan adanya perbedaan distribusi stress dari gaya geser mesio-distal dan serviko-insisal pada tiga jenis rumus bangun dasar braket di permukaan dasar braket, lapisan adhesif ortodonti, permukaan email, dan jaringan periodontal.

---

In Indonesia, the development of domestic production of orthodontic brackets is underway and further studies are needed to find out the design of the basic bracket geometry formula that has the best retention. Metal orthodontic bracket can adhere to teeth surface by relying on mechanical retention in the base of the brackets. Finite element analysis is an analysis using three dimensional model to asses the stress distribution that occurs due to application of shear forces with certain magnitude and direction. The stress concentration and the distribution can be predicted and assumed to be the potential risk of deformity or failure. This study used three types of metal orthodontic brackets which available on the market. Three maxillary first incisors brackets with different bases, maxillary right incisor with periodontal tissue ,bone block, and orthodontic adhesive were construct using a software as a three dimensional model. The model were simulated with the application of shear stress mesio-distal and cervical- incisal one Newton each. Finite element analysis showed there are difference in stress distribution of mesio-distal and cervical-incisal shear stress on three types of different geometry of bracket base on the bracket base surface, orthodontic adhesive layer, enamel surface, and periodontal tissue."

"Polimorfisme genetik MTHFR C677T adalah faktor resiko orofacial cleft (OFC). Dalam mengetahui distribusi genotip dan hubungan polimorfisme MTHFR C677T dengan orofacial cleft, maka diikutsertakan grup OFC dan grup kontrol sebanyak 24 dan 47 sampel ekstraksi DNA dari Laboratorium Biologi Oral FKG UI. Identifikasi molekuler dengan teknik PCR-RFLP. Kedua grup berada dalam Hardy-Weinberg equilibrium. Grup OFC, frekuensi alel C 89.6% dan alel T 10.4% serta tidak ditemukan genotip homozigot variant (TT). Grup kontrol ditemukan 2 individu bergenotip TT, frekuensi alel C 75.5 % dan alel T 24.4 %. Hasil uji Chi-square, polimorfisme MTHFR C677T berhubungan dengan orofacial cleft (p<0.05).

---

MTHFR C677T polymorphism is a possible risk factor for orofacial cleft. In assessing the genotype distribution of MTHFR C677T polymorphism and its relation to orofacial cleft, 24 OFC samples and 47 control samples were included and provided by Oral Biology Laboratory Faculty of Dentistry University of Indonesia. PCR-RFLP technique was used for genotyping. Allelic frequencies in OFC group were 89.6% (C allele) and 10.4% (T allele) while in control group were 75.5% (C allele) and 24.4% (T allele). Genotyping showed two individuals of TT genotype in control group. Polymorphism MTHFR C677T in two groups were in Hardy-Weinberg equilibrium and showed a significant association with orofacial cleft (p<0.05)."