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Alida Widiawaty
"[ABSTRAK
Latar belakang dan tujuan: Akne vulgaris (AV) adalah penyakit peradangan menahun unit pilosebasea yang bersifat swasirna, ditandai dengan lesi pleomorfik berupa papul, komedo, pustul, dan nodul. Pengobatan AV memerlukan waktu yang cukup lama. Penyakit menahun dengan waktu pengobatan yang lama, berdampak terhadap kepatuhan pasien. Kepatuhan pengobatan topikal lebih rendah daripada sistemik. Hanya akne vulgaris ringan (AVR) yang diterapi menggunakan obat-obatan topikal saja. Layanan pesan singkat merupakan salah satu cara yang praktis dan efisien dalam upaya meningkatkan kepatuhan pengobatan AV, dengan pertimbangan prevalensi AV lebih banyak pada usia remaja dan dewasa muda yang merupakan pengguna terbanyak layanan tersebut. Dengan layanan ini, diharapkan pasien tidak lupa menggunakan obat topikal pada AVR. Penelitian ini dilakukan untuk mengetahui efektivitas penggunaan pesan singkat elektronik terhadap kepatuhan pengobatan AVR.
Metode: Studi eksperimen dengan desain randomized controlled trial (RCT) terhadap pasien AVR usia 15-25 tahun yang berobat ke Poliklinik Ilmu Kesehatan Kulit dan Kelamin (IKKK) Rumah Sakit dr. Cipto Mangunkusumo (RSCM). Penelitian ini melibatkan 2 kelompok, yaitu: kelompok intervensi yang mendapat pesan singkat elektronik dan kelompok kontrol. Kedua kelompok diberi pengobatan tretinoin krim 0,05% dan/atau klindamisin gel 1,2% selama 6 minggu.
Hasil: Tidak terdapat perbedaan bermakna antara kepatuhan pengobatan AVR kelompok kontrol dengan kelompok intervensi pada minggu kedua (p=0,376) dan keempat (p=0,432). Namun pada minggu keenam, kelompok intervensi secara bermakna lebih patuh daripada kelompok kontrol (p=0,032).
Kesimpulan: Pesan singkat elektronik meningkatkan kepatuhan pengobatan AVR terutama pada minggu keenam di Poliklinik IKKK RSCM.

ABSTRACT
Background and objectives: Acne vulgaris (AV) is a self limited, chronic inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a long duration of treatment. Chronic disease with a long duration of therapy usually has an impact on adherence. Topical therapy adherence is lower than systemic. Only mild AV is treated with topical medications. Electronic text messaging is a practical and efficient method in order to improve adherence to AV therapy, with a consideration of the AV prevalence are more on teens and young adults who are the majority users of electronic text messaging service. With this method, patients are expected not to forget the use of medication. This study was conducted to determine the effectiveness of electronic text messaging to improve adherence of mild AV therapy.
Methods: Experimental study, randomized controlled trial (RCT) to mild AV patients, age 15-25 years old who came to Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention group who received electronic text messaging, and the contrary is the control group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin 1,2% gel for six weeks.
Results: There were no significant differences in adherence of mild AV therapy between both groups in the second (p = 0.376) and fourth week (p = 0.432). The intervention group was significantly higher in terms of adherence than the control group in the sixth week (p = 0.032).
Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronic
inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions
consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a
long duration of treatment. Chronic disease with a long duration of therapy
usually has an impact on adherence. Topical therapy adherence is lower than
systemic. Only mild AV is treated with topical medications. Electronic text
messaging is a practical and efficient method in order to improve adherence to
AV therapy, with a consideration of the AV prevalence are more on teens and
young adults who are the majority users of electronic text messaging service.
With this method, patients are expected not to forget the use of medication. This
study was conducted to determine the effectiveness of electronic text messaging
to improve adherence of mild AV therapy.
Methods: Experimental study, randomized controlled trial (RCT) to mild AV
patients, age 15-25 years old who came to Dermatology and Venereology Clinic
dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention
group who received electronic text messaging, and the contrary is the control
group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin
1,2% gel for six weeks.
Results: There were no significant differences in adherence of mild AV therapy
between both groups in the second (p = 0.376) and fourth week (p = 0.432). The
intervention group was significantly higher in terms of adherence than the control
group in the sixth week (p = 0.032).
Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.;Background and objectives: Acne vulgaris (AV) is a self limited, chronic
inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions
consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a
long duration of treatment. Chronic disease with a long duration of therapy
usually has an impact on adherence. Topical therapy adherence is lower than
systemic. Only mild AV is treated with topical medications. Electronic text
messaging is a practical and efficient method in order to improve adherence to
AV therapy, with a consideration of the AV prevalence are more on teens and
young adults who are the majority users of electronic text messaging service.
With this method, patients are expected not to forget the use of medication. This
study was conducted to determine the effectiveness of electronic text messaging
to improve adherence of mild AV therapy.
Methods: Experimental study, randomized controlled trial (RCT) to mild AV
patients, age 15-25 years old who came to Dermatology and Venereology Clinic
dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention
group who received electronic text messaging, and the contrary is the control
group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin
1,2% gel for six weeks.
Results: There were no significant differences in adherence of mild AV therapy
between both groups in the second (p = 0.376) and fourth week (p = 0.432). The
intervention group was significantly higher in terms of adherence than the control
group in the sixth week (p = 0.032).
Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital., Background and objectives: Acne vulgaris (AV) is a self limited, chronic
inflammatory disease of pilosebaceous unit, characterized by pleomorphic lesions
consist of papules, comedones, pustules, and nodules. Acne vulgaris requires a
long duration of treatment. Chronic disease with a long duration of therapy
usually has an impact on adherence. Topical therapy adherence is lower than
systemic. Only mild AV is treated with topical medications. Electronic text
messaging is a practical and efficient method in order to improve adherence to
AV therapy, with a consideration of the AV prevalence are more on teens and
young adults who are the majority users of electronic text messaging service.
With this method, patients are expected not to forget the use of medication. This
study was conducted to determine the effectiveness of electronic text messaging
to improve adherence of mild AV therapy.
Methods: Experimental study, randomized controlled trial (RCT) to mild AV
patients, age 15-25 years old who came to Dermatology and Venereology Clinic
dr. Cipto Mangunkusumo Hospital. This study involved two groups: intervention
group who received electronic text messaging, and the contrary is the control
group. Both groups were prescribed tretinoin 0,05% cream and/or clindamycin
1,2% gel for six weeks.
Results: There were no significant differences in adherence of mild AV therapy
between both groups in the second (p = 0.376) and fourth week (p = 0.432). The
intervention group was significantly higher in terms of adherence than the control
group in the sixth week (p = 0.032).
Conclusions: Electronic text messaging improve adherence of mild AV therapy especially in the sixth week at Dermatology and Venereology Clinic dr. Cipto Mangunkusumo Hospital.]"
Jakarta: Fakultas Kedokteran Universitas Indonesia, 2015
T58825
UI - Tesis Membership  Universitas Indonesia Library
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Candra Damis Widiawaty
"Riset ini bertujuan melakukan analisis prosedur desain dan redesain alat penukar kalor tipe shell and tube dengan CFD pada reboiler turbin mikro bioenergi proto x-2 dan CO2 stripper reboiler PT Pupuk Iskandar Muda. Metode desain dimulai dari kalkulasi manual metode Kern dan konstrain desain pressuredrop di sisi tube harus di bawah 277 Pa. Kemudian dilakukan simulasi 1 fasa SolidWork 2010 dan 2 fasa dengan sofware CFDSof. Metode redesain diawali dari analisis kondisi terpasang dilanjutkan dengan redesain dengan 3 model. Fokus redesain adalah untuk menganalisis korosi pendidihan dengan CFD dan perubahan desain untuk mengurangi fraksi uap.
Eksperimen reboiler turbin dan hasil simulasi menunjukkan peningkatan temperatur pada titik ukur 1 lebih cepat dibandingkan dengan titik ukur 2, sehingga uap lebih dulu terbentuk pada titik ukur 1. Hasil simulasi menunjukkan pembentukan uap mulai terjadi pada jarak 85 mm dari tubesheet. Berdasarkan simulasi 2 fasa, model redesain 2 yaitu posisi outlet shell 880 mm dari tubesheet adalah yang terbaik karena proses pendidihan lebih sedikit yang direpresentasikan oleh pembentukan fraksi uap tertinggi hanya 0,0002. Dengan mengunakan simulasi CFD, desain reboiler CO2 stripper reboiler lebih baik dibandingkan desain reboiler turbin, karena pada reboiler CO2 stripper reboiler penguapan terjadi mendekati outlet sehingga uap lebih lebih mudah keluar.
......The aimed of this researched is analized procedure of design and redesign shell and tube heat exchanger used CFD for micro bioenergy gas turbine proto x-2 and CO2 stripper reboiler?s PT Pupuk Iskandar Muda. The design method was started with manual calculation using Kern method and the constrain was pressuredrop exhaust gas must be under 277 Pa. The next step was simulated the model with SolidWork 2010 for one phase and CFDSof for two phase. The method of redesign was previously analized the existing condition and then continued with changed the original model with 3 redesign model which is produced less vapor fraction.
The experiment and simulation of turbine reboiler showed that the temperature of water increasing faster at measuring point 1 than measuring point 2 therefore water vapor started at 85 mm from inlet of exhaust gas. The redesign 2 which is the distance outlet 880 mm from tubesheet was the best design because it's produced the lowest vapor fraction 0,0002. On all the CFD could showed the pendidihan process for both of the reboiler, it showed that the CO2 stripper reboiler design was better than the turbine reboiler because the vaporation was started near the outlet."
Depok: Fakultas Teknik Universitas Indonesia, 2012
T31064
UI - Tesis Open  Universitas Indonesia Library