"Ulser sering ditemukan di mukosa mulut. Rosella dilaporkan dapat mempercepat penyembuhan ulser.
Tujuan: Menganalisis efektivitas ekstrak etanol kelopak bunga rosella teridentifikasi 3.75%.
Metode: sebanyak 36 ekor tikus dibagi 3 kelompok paparan saline, triamcinolone acetonide, ekstrak rosella 3.75%. Tikus dikorbankan pada harike 2, 4, 8, dan 15. Spesimen difiksasi dan dilakukan skoring pada sediaan mikroskopik.
Hasil: Pemaparan saline menunjukkan skor radang 3; pemaparan triamcinolone acetonidepada dua ekor tikus menunjukkan skor radang 1, satu ekor tikus menunjukkan skor radang 2; pemaparan ekstrak rosella 3.75% menunjukkan skor radang 2.
Kesimpulan: Pemaparan ekstrak rosella 3.75% kurang efektif menyembuhkan ulser mukosa mulut.
Ulcers are often found in oral mucosa. Roselle has been reported to accelerate wound healing. Objectives: To analyze the effectiveness of identified ethanol extract of roselle calyx 3.75%. Methods: A total of 36 rats were divided into 3 groups of application, saline, triamcinolone acetonide, and roselle extract 3.75%. Rats were sacrificed on 2nd, 4th, 8th, and 15th days. Specimens were made and microscopic slide were scored. Results: Saline application showed inflammation score 3. Triamcinolone acetonide application showed inflammation score 1. Roselle extract application showed inflammation score 2. Conclusion: Application of roselle extract 3.75% less effective to accelerate wound healing."
Jakarta: Fakultas Kedokteran Gigi Universitas Indonesia, 2013
