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"Tesis ini disusun untuk mengetahui gambaran kualitas hidup pasien adolescence idiopathic scoliosis (AIS). Desain penelitian merupakan studi potong pada 100 pasien AIS yang berusia di atas 13 tahun dengan menggunakan kuesioner Scoliosis Research Society 30 (SRS-30) sebagai alat ukur kualitas hidup. Dilakukan analisis faktor-faktor yang berhubungan yang meliputi faktor penyakit (usia terdiagnosis, derajat keparahan kurva, tipe kurva) faktor terapi (exercise, brace, operasi) dan faktor sosiodemografik (kelompok usia, jenis kelamin, body mass index). Hasil penelitian didapatkan skor total yaitu 3.42 ± 0.46. Didapatkan skor tertinggi pada domain nyeri yaitu 3.66 (2-5), serta skor terendah pada domain citra diri yaitu 3.33 ± 0,9. Pada faktor penyakit, didapatkan skor domain kepuasan terhadap manajemen yang lebih tinggi secara bermakna pada kurva derajat ringan. Pada faktor terapi, didapatkan skor total dan skor domain fungsi yang lebih tinggi secara bermakna pada kelompok exercise, skor domain citra diri dan kepuasan terhadap manajemen yang lebih rendah secara bermakna pada kelompok brace, serta skor domain citra diri yang lebih tinggi, tetapi skor domain fungsi dan kepuasan terhadap manajemen yang lebih rendah secara bermakna pada kelompok operasi. Tidak didapatkan perbedaan skor yang bermakna pada faktor sosiodemografi (usia, jenis kelamin, body mass index).......This thesis aimed to determine the quality of life of patients with adolescent idiopathic scoliosis (AIS). The study design was a cross-sectional study of 100 AIS patients aged over 13 years using the Scoliosis Research Society 30 (SRS-30) questionnaire as a measurement tool of quality of life. Analysis of related factors including disease factors (age at diagnosis, degree of curve severity, type of curve), therapeutic factors (exercise, brace, surgery), and sociodemographic factors (age group, sex, body mass index) was performed. The results showed a total score of 3.42 ± 0.46. The highest score was in the pain domain (3.66 (2-5)), and the lowest score was in the self-image domain (3.33 ± 0.9). In the disease factors, a significantly higher score of satisfaction for management was found in mild degree curve. In the therapeutic factors, a significantly higher total score and function domain score was found in the exercise group, a significantly lower in self-image and satisfaction with management domain score in the brace group, and a significantly higher self-image domain score but lower in function and satisfaction with management domain score was found in the operating group. There were no significant differences in sociodemographic factors (age, gender, body mass index)."

"Pendahuluan : Adolescent Idiopathic Scoliosis (AIS) adalah jenis skoliosis yang paling umum terjadi pada populasi pediatrik, mencakup 80% dari total kasus, dan seringkali mengakibatkan morbiditas serta hendaya kepada penderitanya. Parameter evaluasi Health Related Quality of Life (HRQL) menjadi penting karena AIS mempengaruhi kondisi klinis, sosial, dan psikologis penderitanya. Salah satu kuesioner evaluasi HRQL yang populer adalah Short Form-36 (SF-36), yang bersifat general dan telah diadaptasikan ke bahasa Indonesia. Namun, kuesioner ini tidak spesifik untuk skoliosis. Scoliosis Research Society (SRS) telah mengembangkan kuesioner HRQL spesifik untuk skoliosis, yaitu SRS-22r, yang terdiri dari 5 domain penilaian. Kuesioner ini telah diadaptasi ke berbagai bahasa, tetapi belum ada versi berbahasa Indonesia yang terdaftar di SRS. Oleh karena itu, peneliti berupaya melakukan adaptasi lintas budaya kuesioner SRS-22r agar dapat diaplikasikan pada praktik klinis di Indonesia.Metode : Penelitian ini merupakan studi potong lintang untuk adaptasi lintas budaya, uji validitas dan reliabilitas kuesioner SRS-22r berbahasa Indonesia (SRS-22r INA) pada pasien dengan Adolescence Idiopathic Scoliosis. Penelitian ini menggunakan metode consecutive sampling hingga terpenuhinya kuota sampel, berdasarkan perhitungan besar sampel untuk adaptasi kuesioner menggunakan sampel minimal untuk uji pra final, uji validitas dan uji reliabilitas.Hasil : Terdapat 50 responden perempuan (75.8%) dan 16 responden laki-laki (24.2%). Kurva utama yang paling umum adalah thorasic (75.8%), sedangkan yang paling jarang ditemukan adalah thoracolumbar (3.0%). Sebanyak 69.7% responden dikategorikan sebagai skoliosis dengan sudut berat (Cobb angle >450). Nilai rerata kurva utama adalah 57.33, dengan nilai minimum 10.7 dan maksimum 100.2. Standar deviasi yang relatif tinggi (22.73) menunjukkan besarnya variabilitas data. Kelima domain kuesioner SRS- 22r INA tidak terkena floor effect dan ceiling effect lebih dari 15%. Uji validitas konstruksi menunjukkan bahwa domain SRS-22r INA memiliki korelasi yang tinggi dengan domain SF-36 INA. Hasil Chronbach’s alpha menunjukkan bahwa butir pertanyaan pada domain SRS-22r INA sangat reliabel.Kesimpulan : Berdasarkan hasil adaptasi lintas budaya, uji validitas dan uji reliabilitas kuesioner, SRS-22r INA merupakan kuesioner yang valid dan reliabel. Kuesioner ini dapat digunakan sebagai parameter HRQL untuk evaluasi penderita AIS di Indonesia.......Introduction : Adolescent Idiopathic Scoliosis (AIS) is the predominant form of scoliosis observed in the pediatric patient, constituting approximately 80% of all reported cases, this condition frequently leads to adverse health outcomes and functional impairments among affected patient. The assessment of Health Related Quality of Life (HRQL) is paramount due to the impact of AIS on the clinical, social, and psychological aspects of affected patient. The Short Form-36 (SF-36) is a widely used questionnaire for evaluating HRQL. It is a comprehensive tool that has been developed for use in various populations, including the Indonesian population. Nevertheless, this questionnaire lacks specificity in relation to scoliosis. The Scoliosis Research Society (SRS) has devised a dedicated HRQL survey for scoliosis, known as the SRS-22r. This questionnaire encompasses five distinct domains for evaluation. The present questionnaire has been modified and translated into other languages; nevertheless, it is worth noting that an Indonesian version is not yet included in the SRS. This study aims to conduct a cross-cultural adaptation of the SRS- 22r questionnaire to facilitate its implementation in therapeutic settings within Indonesia. Method : This study aims to achieve cultural adaptation, validity and reliability evaluation of the SRS-22r INA questionnaire in patients with Adolescence Idiopathic Scoliosis through a cross-sectional design. The present study employs the consecutive sampling technique to achieve the desired sample size, as determined by sample size calculations. The questionnaire is adapted through a preliminary testing phase followed by validity and reliability test. In addition, inclusion and exclusion criteria are established to choose participants for the study.Result : There were 50 female respondents (75.8%) and 16 male respondents (24.2%). The most common main curve was thoracic (75.8%), while the least common was thoracolumbar (3.0%). A total of 69.7% of respondents were categorized as scoliosis with a severe angle. The average value of the main curve was 57.33, with a minimum value of 10.70 and a maximum value of 100.20. A relatively high standard deviation (22.73) indicates the amount of data variability. The five domains of the SRS-22r INA questionnaire were not affected by the floor effect and ceiling effect of more than 15%. The construct validity test showed that the SRS-22r INA domain had high correlation with the SF-36 INA domain. Chronbach’s alpha results showed that the question items in the SRS-22r INA domain were highly reliable.Conclusion : Based cross cultural adaptation, validity testing and reliability testing, SRS- 22r INA questionnaire is valid and reliable. This questionnaire can be used as an HRQL parameter for AIS patient in Indonesia."

"Hipertensi adalah peningkatan tekanan darah dan menetap diatas dari batas normal, sebagai akibat terjadinya gangguan sistem sirkulasi darah. Hasil Riset Kesehatan Dasar (Riskesdas 2007) secara nasional, diketemukan prevalensi hipertensi sebesar 31,7 % pada kelompok umur 18 tahun atau lebih serta mulai banyak dijumpai pada kelompok usia muda 15 ? 17 tahun (8,3%). Hasil Riskesdas 2013 hipertensi turun menjadi 25,8 persen tetapi terjadi peningkatan prevalensi hipertensi berdasarkan wawancara (apakah pernah didiagnosis nakes dan minum obat hipertensi) dari 7,6 persen tahun 2007 menjadi 9,5 persen tahun 2013. Tekanan darah remaja bervariasi karena banyak faktor mempengaruhinya. Tujuan penelitian ini adalah untuk mengetahui faktor faktor yang berhubungan dengan terjadinya hipertensi pada kelompok remaja umur 15 ? 24 tahun di Indonesia. Penelitian ini menggunakan rancangan cross sectional dan analisis statistik dilakukan dengan menggunakan regresi logistik berganda. Hasil penelitian menunjukkan bahwa sebanyak 12,2 % remaja mengalami hipertensi. Berdasarkan hasil analisis multivariat dapat diketahui bahwa faktor yang berpengaruh besar terhadap kejadian hipertensi pada remaja adalah obesitas dan umur dengan OR 2,83 dengan 95% CI 2,63 ? 3,03. Umur mempunyai OR 0,42 dengan 95% CI 0,40 ? 0,45. Tidak terdapat interaksi antara obesitas dan umur pada analisis interaksi. Diperlukan upaya dan peran serta berbagai pihak untuk menurunkan prevalensi hipertensi remaja di Indonesia. ......Hypertension is the increase in blood pressure and settled above the normal limit, as a result of impaired blood circulation system. Result basic health Research (Riskesdas 2007), found the prevalence of hypertension of 31.7% in the group aged 18 years or older as well as many found in young age groups 15% u2013 17 years (8.3 percent). Results Riskesdas 2013 hypertension dropped to 25,8 percent but an increase in the prevalence of hypertension based on interviews (if ever diagnosed hypertension drugs and drinking nakes) from 7.6 percent in 2007 to 9.5 percent by 2013. Teen's blood pressure varies due to many factors affected it. The purpose of this research is to know the factors associated with the occurrence of hypertension in adolescent age group 15 - 24 years in Indonesia. This research uses the draft cross sectional and statistical analysis is carried out using multiple logistic regression. The results showed that as much as of teens experiencing 42,70 hypertension. Based on the results of the multivariate analysis can be aware that factors that influence the incidence of hypertension in adolescents is obese and aged with OR 2.83 with 95% CI 2.63 - 3.03. Age have OR 0.42 with 95% CI 0.40 - 0.45. There was no interaction between obesity and age analysis of interaction. It takes effort and involvement of various parties to lower the prevalence of hypertension of teenagers in Indonesia."

"Tujuan dari penelitian ini adalah mengetahui faktor-faktor yang berhubungan dengan perilaku menstruasi pada siswi SMPN 87 Jakarta Selatan tahun 2014. Penelitian ini menggunakan desain cross sectional dengan sampel 252 siswi yang menstruasi dan kuesioner sebagai alat ukur penelitian.Hasil penelitian ini menunjukkan bahwa 64,3% responden telah memiliki perilaku menstruasi yang baik. Berdasarkan uji chi-square, variabel pengetahuan memiliki hubungan dengan perilaku menstruasi (p-value =0,002). Sekolah dapat memanfaatkan mata ajaran Bimbingan Konseling dan kegiatan PMR sebagai wadah pemberian informasi mengenai perilaku menstruasi ataupun membuat pelatihan peer educator. Pelatihan peer educator dapat dilakukan melalui kerjasama dengan pihak yang bergerak di bidang kesehatan reproduksi remaja. Selain itu perlu adanya peningkatan kualitas sarana dan prasarana sekolah terutama ketersediaan sumber air yang lancar dan sabun.

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The purpose of this study was to determine the factors associated with menstruation behaviors of female students in SMPN 87 South Jakarta Year 2014. This study used cross-sectional design with a sample taken are 252 students who has had menstruation and the questionnaire as a measure of research.The results of this study showed that 64,3% of respondents have a good menstruation behaviors. Based on statistical tests with chi-square test, variabel that has a significant association with menstruation behaviors is knowledge (p-value =0,002). This School can use BK and PMR activities to provide information of menstruation behaviours and also training for peer educators. Peer educator trainings can be done through cooperation with organisations operating in adolescent reproductive health fields. Furthermore, quality of school facilities and infrastructures requires improvement, especially in clean running water and soap."

"Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions. "