Hasil Pencarian  ::  Simpan CSV :: Kembali

Abstrak :
Benzene bersifat toksik dan karsinogenik yang ditemukan dalam proses operasional Kilang Paraxylene di PT. X. Dalam proses kerjanya, pekerja terpajan benzene sehingga dilakukan analisa pajanan benzene terhadap pekerja. Desain penelitian adalah analisa kuantitatif dengan metode potong lintang dari data sekunder perusahaan. Variabel penelitian meliputi konsentrasi personal benzene, kadar SpMA, usia, masa kerja, status gizi, kebiasaan merokok, konsumsi alkohol, shift kerja, durasi pajanan per hari dan penggunaan APP dari 64 pekerja. Konsentrasi personal benzene diukur pada breathing zone pekerja berkisar antara 0,02 sd 0,44 ppm. Sebanyak 28 pekerja (43,75%) memiliki kadar SpMA melebihi IPB ACGIH 2021 (25 µg/g kreatinin), UCL 1,95% di semua SEG melebihi IPB, berarti ada ketidakyakinan sebesar 95% bahwa kadar SpMA pekerja Kilang Paraxylene tidak melebihi IPB. Uji korelasi pearson menunjukkan tidak terdapat hubungan yang signifikan antara konsentrasi personal benzene dengan kadar SpMA, p=0,195. Hasil uji statistic menemukan adanya hubungan signifikan antara kadar SpMA dengan masa kerja, p=0,04. Kadar SpMA hanya menggambarkan metabolit di tubuh namun tidak dapat memberikan rute pajanan. Penelitian lanjutan diperlukan untuk menganalisa dampak pajanan benzene pada pekerja yang melebihi durasi aman pajanan benzene pada PT. X. ......Benzene is presence in routine operational activities of Paraxylene Refinery Unit in PT. X. The process exposed the worker to benzene. Hence, the need to analyze its exposure to the workers. The study design was quantitative analysis with cross sectional design by analyzing secondary data. The variables studied were personal benzene, SpMA level, age, length of work, BMI, smoking habit, alcohol consumption, shift/non shift, length of exposure per day, and use of PPE from the sampel of 64 workers. The result showed personal benzene concentrations measured in the breathing zone are below the recommended exposure limit (NAB Permenaker No 5/2018: 0,5 ppm), 28 respondents (43,75%) had SpMA level above the value of BEI ACGIH 2021 (25 µg/g kreatinin ), UCL 1,95% of all SEG is higher than BEI meaning there is 95% inconfident that benzene concentrations in the breathing zones are below the standard. There is no correlation between personal benzene concentrations and SpMA p=0,195. There is a significant correlation between length of work with SpMA level, p=0,04. SpMA is useful in determining benzene exposure even in low level exposure however it does not recognize where benzene is coming from. Implementation of work rotation and benzene awareness need to be improved. Further study should be conducted to analyze risk of cancer to worker who has been exposed to benzene longer than the safe duration of exposure in PT. X.

Abstrak :
Sejak penggunaan benzena, ditemukan juga dampak kesehatan akibat pemajanan dengan bahan kimia ini. Petugas operator pada pengisian BBM adalah salah satu populasi pekerja yang memiliki tingkat resiko pajanan benzena yang tinggi, terutama melalui jalur inhalasi dalam waktu pajanan yang kontinyu. Metode yang digunakan adalah analisis risiko kesehatan lingkungan, yaitu menghitung besar risiko individu dan populasi. Pada estimasi risiko individu, seluruh karyawan belum berisiko efek nonkarsinogenik, tetapi pada pajanan 3 tahun terdapat 1 karyawan yang berisiko efek kanker dan pada pajanan lifetime seluruh karyawan berisiko efek kanker. Seluruh populasi karyawan belum berisiko efek nonkarsinogenik pada semua durasi pajanan. Populasi operator pompa BBM berisiko efek karsinogenik pada durasi pajanan lifetime. Populasi karyawan bagian administrasi belum berisiko efek karsinogenik pada semua durasi pajanan. Disarankan bekerja tidak lebih dari 3 tahun, bekerja selama maksimal 6 jam/hari atau penggunaan APD yang tepat agar terlindung dari risiko kanker. ...... Since the use of benzene, was also found health effects due to exposure to these chemicals. Operators in charge of fuel is one of the working population who have high levels of benzene exposure is high risk, mainly through the inhalation pathway of exposure is continuous in time. The method used is the analysis of environmental health risks, namely large calculating individual and population risk. In the individual risk estimates, the employee has not at risk noncarsinogenic effect, but at 3 years of exposure there is an employee at risk of cancer and the effects on lifetime exposure to all employees at risk of cancer effects. The entire population of non-employee has not at risk of carcinogenic effects in all the duration of exposure. The population at risk of fuel pump operators carcinogenic effect on the duration of lifetime exposure. Populations at risk yet the administrative staff of a carcinogenic effect on all the duration of exposure. Advised to work no more than 3 years, working for a maximum of 6 hours / day or the use of appropriate PPE to protect them from the risk of cancer.

Abstrak :
Latar Belakang: Pria, 48 tahun, pekerja minyak dan gas bumi, didiagnosis dengan myelofibrosis, bagian dari myeloproliferatif neoplasma. Pasien bekerja sebagai operator selama 15 tahun, dimana salah satu hazardnya adalah paparan rendah benzen. Laporan kasus ini bertujuan untuk melihat hubungan antara paparan benzene dengan myeloproliferatif neoplasma pada pekerja minyak dan gas bumi.  Metode:  Analisis PICO digunakan untuk memformula pertanyaan klinik laporan kasus ini, populasi: pekerja, intervensi/paparan: benzen, komparasi: tidak terpapar benzen, hasil: myeloproliferatif neoplasm. Strategi pencarian literatur untuk menjawab pertanyaan klinis menggunakan data basis leektronik pada PubMed, Google Scholar dan daftar pustaka. Kriteria inklusi adalah penelitian etiologik dengan kriteria eksklusi adalah leukemia myeloid kronik dan trombositopenia esensial. Penelitian yang terpilih kemudian dilakukan penilaian kritis untuk menentukan apakah penelitian ini valid, bermakna, dan dapat diaplikasikan terhadap pasien menggunakan kriteria relevansi dari Ofxord Centre untuk kedokteran berbasis bukti pada penelitian etiologik. Hasil: Terdapat satu peneliltian terpilih yaitu penelitian kasus kontrol dari Glass dkk, 2014 (n= 30 kasus dengan n=124 dengan matched controls), hasil dari penelitian ini paparan kumulatif benzene memiliki OR 1.57 (95% CI 0.55-2.78) terhadap myelofibrosis, paparan benzene 2-20 tahun p 0.49 dan OR 4.4 (95% CI 1.29-15). Setelah dilakukan penilaian kritis terhadap penelitian ini dengan hasil poenelitian valid, memiliki kualitas yang tinggi pada pengukuran paparan benzene pada pekerjaan individu. Meskipun terdapat limitasi berupa confounder data seperti tidak tersedianya informasi mengenai kebiasaan merokok, penggunaan alkohol, paparan radiasi dan atau kerentanan genetik.  Kesimpulan: Berdasarkan analisis kasus 7 langkah diagnosis penyakit akibat kerja, dapat disimpulkan bahwa myelofibrosis dapat berhubungan dengan paparan benzen di tempat kerja. ......Background: A 48-years old male, oil and gas worker was diagnosed with myelofibrosis, part of myeloproliferative neoplasm. The patient worked as an operator for 15 years, where one of the hazards was low level of benzene exposure. Hence, this case report is aimed to find the association of benzene exposure with myeloproliferative neoplasm in oil and gas worker. Method:  The following is PICO analysis to formulate clinical question from this case report; Population: worker, intervention/exposure: benzene, comparison: not exposed to benzene, outcomes: myeloproliferative neoplasm. Literature searching strategies for answering the clinical question used electronic database in PubMed, Google Scholar, and list of references. The inclusion criteria is etiologic research study, while the exclusion criteria are chronic myeloid leukaemia and essential thrombocythemia. The selected papers were then critically appraised to determine whether the article is valid, meaningful, and applicable to the patient using relevant criteria bye the Oxford Centre for Evidence-based Medicine for etiological study. Result: Finally, one study was selected; a case control study by Glass et al, 2014 (n=30 cases with n=124 matched controls), the outcome of this study was OR of 1.57 (95% CI 0.55-2.78) for cumulative benzene exposure, p 0.49 and OR of 4.4 (95% CI 1.29-15) for a 2-20 years benzene exposure, p 0.018. After a critical appraisal, it was found that this article was valid, the study has high quality and precise benzene exposure metrics based on exposure of individual job. However, there were potential limitations on confounders data such as not available data on smoking habit, alcohol use, radiation exposure and/or genetic susceptibility. Conclusion: Based on the case analysis through 7 (seven) steps of occupational disease diagnosis and journal critical appraisal, it can be concluded that the myelofibrosis may be related to exposure to benzene at the workplace.