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Abstrak :
Latar belakang: Gel ekstrak daun sirih memiliki kandungan tanin yang merupakan agen kromogenik yang dapat memberikan efek diskolorasi ekstrinsik pada email gigi. Tujuan: Mengetahui perbedaan pengaruh gel ekstrak daun sirih terhadap perubahan warna email gigi akibat. Metode: Delapan belas spesimen gigi premolar manusia dibagi menjadi tiga kelompok perlakuan, yaitu aplikasi gel ekstrak daun sirih konsentrasi 15% (n=6), 25% (n=6), dan 35% (n=6), serta pengukuran nilai warna dilakukan tiap 1 bulan (5 kali aplikasi), 3 bulan (15 kali aplikasi), dan 6 bulan (26 kali aplikasi) menggunakan VITA Easyshade®. Perhitungan perubahan warna dilakukan dengan rumus CIEL*a*b*. Hasil: Dari uji statistik Repeated ANOVA, terdapat perbedaan perubahan warna yang bermakna antar lamanya aplikasi gel ekstrak daun sirih 1, 3, dan 6 bulan. Kesimpulan: Pengaplikasian gel ekstrak daun sirih dapat meningkatkan perubahan warna email gigi seiring dengan lamanya aplikasi.

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Background: Gel with betel leaf extract contains tannin that a chromogenic agent which gives extrinsic discoloration effect on tooth enamel. Objectives: To determine the effect of gel with betel leaf extract to the color change of tooth enamel. Methods: Eighteen specimens of premolar teeth were divided into three groups, namely betel leaves extract gel application with concentrations of 15% (n=6), 25% (n=6), and 35% (n=6). The measurement of color value performed before application, 1 month (5 times of applications), 3 months (15 times of applications), and 6 months (26 times of applications) using VITA Easyshade®.The calculation of discoloration was calculated by the CIEL*a*b* formula. Result: From statistical test (Repeated ANOVA), there was a significant color change among length of betel leaf extract gel applications 1, 3, and 6 months. Conclusion : Application of betel leaf extract gel could increase the color change of tooth enamel along with the length of the application.

Abstrak :
Penelitian daun sirih hijau sebagai antibakteri penyakit mastitis sapi perah telah dilakukan. Penelitian bertujuan daun sirih dapat sebagai pengganti antibiotik terhadap penyakit mastitis. Sebanyak 144 sampel susu mastitis dikoleksi dari daerah peternakan dataran rendah 250 m dpl, menengah 450 m dpl dan tinggi 720 m dpl. Bakteri diidentifikasi, diisolasi dan diuji daya antibakteri menggunakan ekstrak daun sirih konsentrasi 6,25; 12,5; 25 dan 50 b/v secara in vitro. Hasil yang diperoleh menunjukkan efektivitas ekstrak daun sirih konsentrasi 50 dibandingkan antibiotika komersial Lactaclox adalah berturut-turut 63,94; 66,23 dan 80,89 di dataran rendah, menengah dan tinggi. Secara in vivo, ekstrak daun sirih signifikan dapat menurunkan jumlah bakteri P.

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Research an antibacterial green betel leaf of dairy cow against mastitis diseases have carried out. The aims of the study to examine the ability of extract leaf medicinal plant against bacterial mastitis at dairy farm in three level of altitudes lower 250 m, moderate 450 m and high land 720 m. Four concentrations of extract leaf were 6.25 12.5 25 , and 50 b v which be done in vitro. The results revealed that the effectiveness extract leaf high at 50 compare to the commercial antibiotics were 63.94 66.23 and 80.89 at low, moderate and high altitude, respectively. Moreover, in vivo study was resulted significantly different P.